@manojpandey66 @tpchaturvedibhu @sankha_shubhra @DrVNMishraa Menthol युक्त एक्सटर्नल यूज़ के तमाम प्रोडक्ट के पर कुछ कार्य हुआ है। जैसे https://t.co/GDdGh0QYfv परंतु ब्रेन के स्नायुतंतुओं पर सीधे असर डाल कर neural degeneration/cerebral atrophy (नसों के कमजोर होने का यही अर्थ लगाया हूँ) कैसे करता है, इसको जानने का प्रयास कर रहा हूँ।
The role and mechanism of action of menthol in topical analgesic products.
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Mar 2020 – Jul 2025Where it's discussed
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News59 articles
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X / Twitter4 posts
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YouTube3 videos
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Discussions reflect a balanced curiosity about menthol’s molecular actions, such as its activation of TRPM8 channels, and its potential to develop new nonopioid pain medications. The tone varies from technical to speculative, demonstrating both interest and recognition of the research’s significance.
Most posts acknowledge the scientific findings, with some expressing support for the implications of menthol's mechanisms.
Discussions show moderate curiosity about menthol’s molecular effects and potential applications.
Posts touch upon detailed mechanisms like TRPM8 channels and debates about its therapeutic impact, indicating a certain level of engagement.
Participants consider the research important, suggesting it could influence future pain relief strategies or medical treatments.
Abstract in brief
- Menthol has been used as a nonopioid pain reliever throughout history, and recent research highlights its action on TRPM8 channels, which are involved in sensing cold and pain.
- It works as a counterirritant by creating a cooling sensation, initially stimulating nociceptors (pain sensors) and then desensitizing them, which helps reduce pain.
- Understanding menthol's molecular mechanism may help develop new nonopioid pain medications, especially topical treatments, as an alternative to opioids for managing pain.]
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Most liked on X and Bluesky#Menthol is a selective activator of transient #receptor potential #melastatin_8 (#TRPM8) channels & a vasoactive compound. It acts as a counter‐irritant by imparting a cooling effect and by initially stimulating #nociceptors and then desensitizing them. [https://t.co/8F3W3jZEF0] https://t.co/3lLVrLaT5p
The role and mechanism of action of #menthol in topical analgesic products https://t.co/8SAeVwYapv
https://t.co/GTsm7ZU7Kz @Trump @DonaldJTrumpJr @EricTrump @GovernorPerry @EmenoguPhillip1 @jaredkushner
All mentions
Review of Topical Menthol-Based Pain Relief Products for Muscle and Joint Pain
Dr. David reviews four Icy Hot products, discussing their active ingredients and their use for muscle and joint pain relief, particularly in arthritis. Insights on menthol's role as a counterirritant and its molecular…
Evaluating Hempvana Arthritis Relief Gel and Menthol's Pain Relief Role
Dr. David reviews Hempvana Arthritis Relief Gel, highlighting its menthol-based cooling effect and hemp seed oil's moisturizing properties. The video discusses its use for joint pain and explores menthol's mechanism as…
Analysis of AleveX Topical Pain Relief and Menthol Mechanism of Action
AleveX Pain Relieving Lotion and Spray are naturally based topical products that do not contain naproxen. Dr. David explains their active ingredients, camphor and menthol, and discusses their use for joint arthritis…
https://t.co/GTsm7ZU7Kz @Trump @DonaldJTrumpJr @EricTrump @GovernorPerry @EmenoguPhillip1 @jaredkushner
@manojpandey66 @tpchaturvedibhu @sankha_shubhra @DrVNMishraa Menthol युक्त एक्सटर्नल यूज़ के तमाम प्रोडक्ट के पर कुछ कार्य हुआ है। जैसे https://t.co/GDdGh0QYfv परंतु ब्रेन के स्नायुतंतुओं पर सीधे असर डाल कर neural degeneration/cerebral atrophy (नसों के कमजोर होने का यही अर्थ लगाया हूँ) कैसे करता है, इसको जानने का प्रयास कर रहा हूँ।
The role and mechanism of action of #menthol in topical analgesic products https://t.co/8SAeVwYapv
#Menthol is a selective activator of transient #receptor potential #melastatin_8 (#TRPM8) channels & a vasoactive compound. It acts as a counter‐irritant by imparting a cooling effect and by initially stimulating #nociceptors and then desensitizing them. [https://t.co/8F3W3jZEF0] https://t.co/3lLVrLaT5p