PubHawk
J Neuroimmune Pharmacol December 2018 PMID 29556883

Cannabis Addiction and the Brain: a Review.

Amna Zehra, Jamie Burns, Christopher Kure Liu, Peter Manza, Corinde E Wiers, Nora D Volkow, Gene-Jack Wang

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Mentions

164
Peak: 63 in Mar 2022
across 5 sources since Jan 2019

Extended reach

1,120,787
potential audience

Total likes

5,232

Video views

58,026

Mentions per month

Jan 2019 – Oct 2025

Where it's discussed

  • X / Twitter99 posts
  • News53 articles
  • Facebook6 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

Overall, people are strongly acknowledging the neurobiological evidence presented in the review, citing examples like the DSM5's recognition of withdrawal syndrome and referencing numerous scientific articles that confirm cannabis's addictive potential. The tone combines scientific referencing with debates about the nature of dependence, reflecting deep engagement and concern over impacts on public health and perceptions.

AgreementModerate agreement

Most discussions support the conclusion that cannabis can be addictive, referencing scientific reviews and epidemiological data.

InterestHigh interest

The discussions show a high level of interest, with participants referencing multiple scientific studies, models of addiction, and debates on the nature of cannabis dependence.

EngagementModerate engagement

Users engage actively by citing research articles, discussing neurobiological models, and debating the addictive potential, indicating thoughtful and in-depth engagement.

ImpactModerate impact

The social discussions could influence perceptions about cannabis use and policy, emphasizing the importance of scientific evidence in shaping opinions.

Abstract in brief

  • Cannabis is the most used illegal substance in the U.S. after alcohol and tobacco, and recent trends show increasing cannabis use disorder (CUD) and decreasing perceived risks.
  • The review uses Koob and Volkow's neurobiological model of addiction, which describes three stages of brain changes caused by repeated substance use that sustain addiction.
  • Research indicates that cannabis-related addiction follows this three-stage framework similarly to other drugs, but with some differences, emphasizing the need for further studies on brain changes in humans with CUD.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Bheatrix
@BheatrixB · X

e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oPPoffnvSI / https://t.co/Oi0OJmDcP2

Mar 22, 2022 · 4,046 likes · 105 shares · 8,366 followers View post →
Amir Grinstein מחקרהתנהגותי#
@AmirGrinstein · X

אתם מציעים שאלות #מחקריות ואני מנסה למצוא מחקרים רלבנטיים. בהקשר של קנאביס, מחקרים חדשים מדברים על 9-10% ממשתמשי קנאביס שהופכים למכורים. https://t.co/DdAYsK4r7c ויש מגוון השפעות על המוח. מאמר אחד עושה סיכום של כל מה שהתחלנו ללמוד על הנושא החדש הזה: https://t.co/ppIw9btUCX https://t.co/9ssuh8RHpB https://t.co/KTYNn4EAu2

Nov 7, 2024 · 2 likes · 6,472 followers View post →
AjiLimo
@sebastialegre · X

@didialcoser @lisrebeldia @AmaliaAlcoser https://t.co/Hm1XllVIuX

Jan 13, 2021 · 2 likes · 179 followers View post →
The Crypto Dog
@TheCryptoDog · X

@eklectic101 @Kyle32775753 If you'd like to learn more, this review is good reference https://t.co/7iArHyUoCh

Aug 5, 2022 · 1 like · 858,814 followers View post →
Dr. Jessica Giddens DNP (nurse)
@DrJGiddensRN · X

@JohnFKtweets @HDVGemstones https://t.co/Nsfo07AhKu

Aug 26, 2020 · 1 like · 2,752 followers View post →
Dr. Bilardo
@drbilardo_ · X

@SrVelcro @Dr_GaIIardo @pagina12 Por eso te digo, y me manejo con medicina basada en la evidencia. Te dejo el articulo, croto adicto. https://t.co/qEuqhUi10M

Jul 20, 2023 · 1 like · 1,492 followers View post →

All mentions

Chris Breadon
@chrisbreadon · X

@kynohy @ClarkeMicah @182_DuncH Slowly but slowly addiction and marijuana as a reaity ...banzai Cannabis Addiction and the Brain: a Review https://t.co/b7vv4PFxLh

Oct 13, 2025 · 204 followers View post →
Chris Breadon
@chrisbreadon · X

@kynohy @no_smoking_1970 @ClarkeMicah @gurprinderdeep Peter drip data feeds at particularly narrow area of the problem with cannabis use and avoids addiction . Yet it's treatment surely must be addressed. along with criminalisation. Cannabis Addiction and the Brain: a Review https://t.co/b7vv4PEZVJ

Oct 12, 2025 · 204 followers View post →
Nero Yana
@heewirh · X

« Non addictif » : C’est contredit par une revue de la littérature de 2018, qui confirme au contraire que l’usage du cannabis coche toutes les cases de l’addictogénicité. https://t.co/hRxS3siSwt https://t.co/8EsXlkiaxm

Mar 22, 2025 · 186 followers View post →
Giga Boloss
@Gigaboloss · X

@MalinHecto65384 @ExhoPapa @JValchamp @collectifPCP OK Hector. https://t.co/W0pvGDtzjc Addiction. https://t.co/nWf6pf668y Mortalité. https://t.co/PFWhhfsoha Mortalité x2 https://t.co/MhmzAJzjIi "Guérison du cancer."

Mar 22, 2025 · 55 followers View post →
Amir Grinstein מחקרהתנהגותי#
@AmirGrinstein · X

אתם מציעים שאלות #מחקריות ואני מנסה למצוא מחקרים רלבנטיים. בהקשר של קנאביס, מחקרים חדשים מדברים על 9-10% ממשתמשי קנאביס שהופכים למכורים. https://t.co/DdAYsK4r7c ויש מגוון השפעות על המוח. מאמר אחד עושה סיכום של כל מה שהתחלנו ללמוד על הנושא החדש הזה: https://t.co/ppIw9btUCX https://t.co/9ssuh8RHpB https://t.co/KTYNn4EAu2

Nov 7, 2024 · 2 likes · 6,472 followers View post →
Trevor
@trevor_______ · X

@rocknrolldr74 @02_reu Fake news. https://t.co/zXeIrrKgBd https://t.co/uIwSouBGg3

Mar 4, 2024 · 370 followers View post →
schnillgritzel
@schnillgritzel · X

@David75Pink @SchleimStephan @hanfverband https://t.co/Ec2ZAxExxu

Feb 12, 2024 · 1,429 followers View post →
schnillgritzel
@schnillgritzel · X

@SchleimStephan @hanfverband https://t.co/AA3mckXmmj

Feb 12, 2024 · 1,429 followers View post →
Devon Wallace
@DevWallace1 · X

@BryVen54 @thehill The original lead researcher of the New Zealand study, Meier, later explored alternative explanations for the association. A 2018 review examines this and other follow-up studies. It found that cannabis did not cause the IQ decline: [Zehra et al. 2018] https://t.co/lyAkiWwMyU

Sep 1, 2023 · 423 followers View post →
Dr. Bilardo
@drbilardo_ · X

@SrVelcro @Dr_GaIIardo @pagina12 Por eso te digo, y me manejo con medicina basada en la evidencia. Te dejo el articulo, croto adicto. https://t.co/qEuqhUi10M

Jul 20, 2023 · 1 like · 1,492 followers View post →
Professora do BRICS
@profa_analucia · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Jan 15, 2023 · 105 shares · 3,579 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

Cannabis Addiction and the Brain: a Review https://t.co/SlWpCWtmcQ

Oct 24, 2022 · 9,038 followers View post →
PattyK.
@xontrikaiasximi · X

@KakosLykos3 @polikoarkoudi @KostasVL @mariaSS9999 Στο DSM5 υπάρχει πλέον το cannabis withdrawal syndrome. Ένα σχετικά προσφατο review για τους μηχανισμούς εξάρτησης: https://t.co/6KF287U96L

Sep 24, 2022 · 614 followers View post →
The Crypto Dog
@TheCryptoDog · X

@eklectic101 @Kyle32775753 If you'd like to learn more, this review is good reference https://t.co/7iArHyUoCh

Aug 5, 2022 · 1 like · 858,814 followers View post →
DGSM
@DGSchlafmedizin · X

(7/7) Quellen: ***Amna Zehra, Jamie Burns, Christopher Kure Liu, Peter Manza, Corinde E. Wiers, Nora D. Volkow, Gene-Jack Wang: Cannabis Addiction and the Brain: a Review. Journal of Neuroimmune Pharmacology (2018) 13:438–452 https://t.co/nFFj22uIgX).

Apr 20, 2022 · 1,083 followers View post →
Bheatrix
@BheatrixB · X

@castaing_jorge + o segundo é uma revisão que analisou mais de 100 estudos sobre o tema, e o terceiro é um estudo longitudinal feito com uma amostra de 1989 gêmeos. 1) https://t.co/oPPoffnvSI 2) https://t.co/V3EENvWKGm 3) https://t.co/lPAFLTsxzm

Mar 30, 2022 · 8,366 followers View post →
Vic
@vicribx · X

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Mar 25, 2022 · 105 shares · 35 followers View post →
K-Boy
@Willyhr · X

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Mar 25, 2022 · 105 shares · 302 followers View post →
Bibi
@beatriistee · X

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Mar 24, 2022 · 105 shares · 357 followers View post →
rose
@langdonspirit · X

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helena.
@lrhelenarl · X

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snaKami, porque the life snak3.
@pervit_in · X

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Cogumelo
@omjr90 · X

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Mar 24, 2022 · 105 shares · 21 followers View post →
.
@eduardavicx · X

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Dora Cachaceira
@eusouanavaleria · X

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Iris - a Deusa Grega, não a Egípcia!
@IrisMaria_Lac · X

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jessica |
@sramalisorn · X

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Victor Van Grogh
@marmotapotiguar · X

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miranda
@carlosmirandd · X

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coelhoformentim
@coelhoformentim · X

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miri
@cloretodio · X

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the bitch is back
@fckeginger · X

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@Arvoresss · X

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@SociaisAmorim · X

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manic pixie dream girl
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Bya
@PropriaBarbie · X

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@malvadonacrf · X

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lena
@writersmile · X

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sky
@bluepinkbook · X

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@Bmar_cos · X

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@ar_adriano · X

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nalu ✨
@nalu1ara · X

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Tio Dani
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sarinha⁷
@tygirlcrf · X

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R.
@raphaelrocker · X

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@liamarques223 · X

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@anturiae · X

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@meiocentro · X

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Kah - A guerra da Papoula
@RainhaJudeD · X

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@vyllckart · X

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@RicaRPResende · X

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@israelsmattos · X

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@EnzoJay4 · X

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this barbie regenerated into David Tennant
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bagriel bera
@garoto_gab · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 23, 2022 · 105 shares · 465 followers View post →
La Isa Bonita
@iggk_ · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 23, 2022 · 105 shares · 79 followers View post →
ツ LYZIN, THE BLOBFISH ツ #ArteViva
@morto_so · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 23, 2022 · 105 shares · 861 followers View post →
jvdojockey3
@jvdojockey3 · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 23, 2022 · 105 shares · 964 followers View post →
Romulo Cardoso
@ro_mulera · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 22, 2022 · 105 shares · 259 followers View post →
Nada consta
@gorgonbacaxi · X

RT @BheatrixB: e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oP…

Mar 22, 2022 · 105 shares · 830 followers View post →
Bheatrix
@BheatrixB · X

e pra quem pediu fontes, segue alguns artigos científicos de revisão sobre o tema: https://t.co/YpM1pU3lSA / https://t.co/oPPoffnvSI / https://t.co/Oi0OJmDcP2

Mar 22, 2022 · 4,046 likes · 105 shares · 8,366 followers View post →
83221n4ndr34
@83221n4ndr34 · X

@mattegeo @annak65649009 @acino2020 @vundegesa non ho voglia di mettermi a parlare degli effetti negativi della cannabis ti posto una systematic review sugli effetti al cervello https://t.co/n6yCBje9Sb uno sui problemi nel dormire perché mi pare interessante https://t.co/7RrH3gicJT.

Jan 24, 2022 · 1,311 followers View post →
Devon Wallace
@DevWallace1 · X

@samhsagov 2nd step: stop using refuted propaganda. The original lead researcher of the New Zealand study, Meier, explored alternative explanations for the association. A 2018 review examines this. It found that cannabis did not cause the IQ decline: https://t.co/lyAkiWwMyU

Jan 12, 2022 · 423 followers View post →
ApexMachina
@apex_machina · X

@TheRightsWriter @realDailyWire Here. This supports that less than 10% rate of addiction and that seems to only apply to chronic use. It also talks about how any addiction is neurological and not chemical. A person can be addicted to McDonalds on a neurological level. https://t.co/UAsuegwMU3

Oct 28, 2021 · 204 followers View post →
REACHING_GNOSIS
@REACHING_GNOSIS · X

https://t.co/JUkeeHgFmG https://t.co/xRnV4tEBcT most cannabis studies now ive seen just outright refer to it as an addiction instead of furthering the pointless debate

Oct 17, 2021 · 1 like · 308 followers View post →
Greenthumb_one
@Greenthumb_one · X

Interesting data... Cannabis Addiction and the Brain: a Review https://t.co/AlolrNVlAi https://t.co/O1UTs24O1V https://t.co/1qLUkVQm6o

Oct 10, 2021 · 4,511 followers View post →
ArdenWeald
@ArdenWeald · X

@Nicochoco6 @Jahlen69 @GDarmanin En bref, si tu veux prouver que le cannabis est inoffensif, tu vas de voir infirmer ces 3 études parues dans des revues scientifiques reconnues mondialement. Bonne chance. https://t.co/odsomtwlyO https://t.co/Sh9tRRXpWu https://t.co/4nOFAOGe80

Aug 24, 2021 · 1 like · 33 followers View post →
Brooke
@BrookeAshh21 · X

@_brymalv_ @OJIBAJO @GEMMALINAAAAA @SERENEHAUGHTY @moisturizednerd https://t.co/F4PEArlamJ "With a recent increase in the rates of cannabis use disorder (CUD) and a decrease in the perceived risk of cannabis use, it is imperative to assess the addictive potential of cannabis." https://t.co/wjQsm9951h https://t.co/Ls7T9CHTg1 All support :)

Jun 5, 2021 · 84 followers View post →
François Booream
@BooraemFrancois · X

https://t.co/AvIrLqWChf

Mar 31, 2021 · 717 followers View post →
I’m the problem, it’s me
@StefBeta · X

(PDF) Cannabis Addiction and the Brain: a Review para los que dicen que no genera adicción, si lo hace solo que no es física, es psicológica. No está bien que la consuman para absolutamente todo, infórmense y chequen si ya son dependientes https://t.co/C0TZBxLaGW

Feb 15, 2021 · 1 like · 297 followers View post →
AjiLimo
@sebastialegre · X

@didialcoser @lisrebeldia @AmaliaAlcoser https://t.co/Hm1XllVIuX

Jan 13, 2021 · 2 likes · 179 followers View post →
Dr. Jessica Giddens DNP (nurse)
@DrJGiddensRN · X

@JohnFKtweets @HDVGemstones https://t.co/Nsfo07AhKu

Aug 26, 2020 · 1 like · 2,752 followers View post →
Dr. Jonathan N. Stea
@jonathanstea · X

@melrod42 @drpaolandmd @AubreeAdams4 @RyanMarino @CaulfieldTim @DrLindaMD @StephenHupp @psychunseen @drjessigold @TheSGEM @DrKathrynGordon @drninashapiro @DrvanTilburg There are different scientific models of addiction that rest upon a wealth of evidence. E.g., As we’ve discussed cannabis in the past, this one discusses a neurobiological model in context of cannabis: - https://t.co/gNrmmzRyPU - another model: https://t.co/PCDfXqX9l9

Jul 16, 2020 · 48,501 followers View post →
blanco y viciado
@II05713735 · X

@GoldenTriumph @jorgevargascub @mafezamorasm @NESTORPAZPOLO @AlbertoBelaunde https://t.co/Wik43AyEHZ es un review de research papers. Hasta donde se sabe es adictivo. https://t.co/3Nrek0Mrnk

Jun 26, 2020 · 178 followers View post →
Pensador Argentino
@Argpensador · X

@eldocto201 @MarcePCsolution @DeAcaEnMas951 @Metro951 @SabinaFrederic @PatoBullrich Es altamente adictiva. Sobre estas cosas hay que leer en Pubmed que es el sitio donde están casi todos los papers (investigaciones) médicas serias del mundo. No en la revista thc hecha por faloperos de cuarta. https://t.co/UPZv2sFwmT

Dec 24, 2019 · 4,318 followers View post →
Mrs.Bang
@ninakooh · X

RT @ploypotter: ใครสนใจเรื่องกัญชาว่าคืออะไร เสพติดได้หรือไม่อย่างไร ลองอ่านดู~ FAQ เกี่ยวกับกัญชา โดย National Institute on Drug Abuse (…

Dec 11, 2019 · 1 share · 452 followers View post →
Milani
@ChefMilzzy · X

RT @bonkers_bee: Cannabis Addiction and the Brain: a Review | SpringerLink ⁦@JrManqoba⁩ https://t.co/gxBmqIci3G

Jul 8, 2019 · 1 share · 8,827 followers View post →
Bongi
@bonkers_bee · X

Cannabis Addiction and the Brain: a Review | SpringerLink ⁦@JrManqoba⁩ https://t.co/gxBmqIci3G

Jul 8, 2019 · 1 share · 5,148 followers View post →
anmuy
@gojogil · X

RT @agneseka94: @TEPOQQ @dhil_with_it @tubirfess Yep, trus long-term use juga bisa bikin lost memories juga. Kemungkinan banyak efek yg mun…

Apr 1, 2019 · 1 share · 141 followers View post →
Agnes
@imnyez · X

@TEPOQQ @dhil_with_it @tubirfess Yep, trus long-term use juga bisa bikin lost memories juga. Kemungkinan banyak efek yg muncul dari kecanduan ganja. https://t.co/2QxmjyScRt

Apr 1, 2019 · 1 share · 265 followers View post →
Air Force Pam
@airforcepam · X

@JaneStanley64 Another cannabis addiction article https://t.co/h5Q9TfOvdq

Mar 12, 2019 · 4,140 followers View post →
Sietkavy Pryvid
@netnazgul · X

@112by @Motolko https://t.co/IyWDN2aDBL

Jan 23, 2019 · 1 like · 94 followers View post →