June 2019 PMID 29572676

Winter cholecalciferol supplementation at 55°N has little effect on markers of innate immune defense in healthy children aged 4-8 years: a secondary analysis from a randomized controlled trial.

Hanne Hauger, Christian Ritz, Charlotte Mortensen, Christian Mølgaard, Stine Broeng Metzdorff, Hanne Frøkiær, Camilla Trab Damsgaard

Download social card

Mentions

4
Peak: 2 in Jun 2025
across 2 sources since Dec 2020

Extended reach

87,516
potential audience

Total likes

1,034

Video views

31,562

Mentions per month

Dec 2020 – Jul 2025

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect an understanding of the nuanced findings, with posts citing that correct dosing can reduce sick days, which contrasts with the study's conclusion of limited overall effects. The tone balances skepticism and interest, highlighted by phrases like 'When Dosed Correctly' and references to specific dosage effects, indicating that participants are engaging thoughtfully with the research but recognize its limited impact on broad health outcomes.

AgreementModerate agreement

Most discussions acknowledge that the study found limited effects of winter vitamin D supplementation on immune markers, aligning with the publication's results.

InterestModerate interest

Posts show moderate curiosity, with some emphasizing the potential benefits of proper dosing, like the mention that vitamin D 'cuts sick days by 17%', indicating interest but not overwhelming curiosity.

EngagementModerate engagement

Participants reference specific details such as dosage effects and infection rates, demonstrating a reasonable level of engagement and analysis.

ImpactNeutral impact

While some posts reflect on the practical implications, like vitamin D's role in health, overall discussions do not suggest a profound shift in understanding or practice, leading to a neutral impact score.

Abstract in brief

  • This study examined whether taking vitamin D supplements during winter affects immune system markers in healthy children aged 4 to 8 years, finding that higher doses (20 µg/day) somewhat prevented declines in certain immune markers but overall had little impact on respiratory infections or most immune responses.
  • Children receiving 10 µg/day of vitamin D showed no significant changes in immune markers, while those taking 20 µg/day maintained some immune functions better than the placebo group, suggesting a dose-dependent effect of vitamin D on innate immunity.
  • Despite these effects on specific markers, vitamin D supplementation did not significantly reduce respiratory infections in these children, indicating that the immune benefits of winter vitamin D may be limited or require additional factors to influence infection rates.]

Top posts

Most liked on X and Bluesky
Jeff Robinson, CEO and Chairman of $MRES and $RLAB
@contrariansmind · X

When Dosed Correctly, Vitamin D Cuts Sick Days by 17% https://t.co/nCwBEFYOU2 via @YouTube @m2bio

Jun 3, 2025 · 1 like · 55,779 followers View post →
Documents Delivered, LLC
@DocsDel · X

Winter cholecalciferol supplementation at 55°N has little effect on markers of innate immune defense in healthy children aged 4-8 years: a secondary analysis from a randomized controlled trial https://t.co/MZPvQYTAeN

Dec 30, 2020 · 176 followers View post →

All mentions

Jeff Robinson, CEO and Chairman of $MRES and $RLAB
@contrariansmind · X

When Dosed Correctly, Vitamin D Cuts Sick Days by 17% https://t.co/nCwBEFYOU2 via @YouTube @m2bio

Jun 3, 2025 · 1 like · 55,779 followers View post →
Documents Delivered, LLC
@DocsDel · X

Winter cholecalciferol supplementation at 55°N has little effect on markers of innate immune defense in healthy children aged 4-8 years: a secondary analysis from a randomized controlled trial https://t.co/MZPvQYTAeN

Dec 30, 2020 · 176 followers View post →