May 2018 PMID 29575374

Gene therapy clinical trials worldwide to 2017: An update.

Samantha L Ginn, Anais K Amaya, Ian E Alexander, Michael Edelstein, Mohammad R Abedi

Mentions

19
Peak: 2 in Dec 2022
across 4 sources since Oct 2018

Extended reach

124,600
potential audience

Total likes

1,079

Video views

40,670

Mentions per month

Oct 2018 – Oct 2024

Where it's discussed

  • News9 articles
  • X / Twitter6 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions highlight key points like the increase in trial numbers and shifts in vector types, with phrases like 'super cool' and questions about US trial counts showing curiosity and enthusiasm. The tone, marked by interest and inquiry, underscores a high regard for the article's insights and relevance.

AgreementModerate agreement

Most discussions acknowledge the significance of the publication, especially noting the growth and evolving trends in gene therapy trials.

InterestHigh interest

Posts indicate strong interest, with mentions of comparisons over time and curiosity about geographic and methodological shifts.

EngagementModerate engagement

Some users engage by questioning specific data points and elaborating on trends, reflecting thoughtful engagement.

ImpactModerate impact

The discussions suggest recognition of the article’s influence in understanding the development and future of gene therapy research.

Abstract in brief

  • As of late 2017, nearly 2,600 gene therapy clinical trials have been completed, are ongoing, or approved worldwide, involving 38 countries and a variety of disease targets.
  • The analysis covers trial details such as geographic distribution, disease indications, types of vectors used, and transferred genes, with data compiled from multiple sources like databases, publications, and investigators.
  • Recent key trends include the growing use of chimeric antigen receptor T cells for cancer treatment and advances in genome editing technologies, which could significantly impact the future of gene therapy.

Top posts

Most liked on X and Bluesky
DoctorRay
@DrNoMask · X

Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Jun 17, 2021 · 4 likes · 4 shares · 31,380 followers View post →
Tyler J Ford
@TyFordFever · X

For those interested in the clinical landscape for #GeneTherapy - this article is super cool. It's from 2017, but it's interesting to look back at the 2012 version and see how things have changed (down w/ retro/plasmid/AdV up w/ AAV/lenti) https://t.co/T1hUfvp9jh

Mar 20, 2019 · 2 likes · 1,137 followers View post →
DoctorRay
@DrNoMask · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Dec 14, 2022 · 4 shares · 31,380 followers View post →
Zach Brennan
@ZacharyBrennan · X

@AlecGaffney is the chart on the number of trials just active US? Worldwide numbers looks like a whole lot more https://t.co/m48JRCIucQ

Oct 1, 2019 · 11,007 followers View post →
IP4PI
@IP4PI · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Nov 15, 2021 · 4 shares · 7,420 followers View post →
Marcie Renee
@MarcieRenee1 · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Dec 14, 2022 · 4 shares · 1,465 followers View post →

All mentions

Marcie Renee
@MarcieRenee1 · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Dec 14, 2022 · 4 shares · 1,465 followers View post →
DoctorRay
@DrNoMask · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Dec 14, 2022 · 4 shares · 31,380 followers View post →
IP4PI
@IP4PI · X

RT @DrNoMask: Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Nov 15, 2021 · 4 shares · 7,420 followers View post →
DoctorRay
@DrNoMask · X

Gene therapy clinical trials worldwide to 2017: An update https://t.co/DIYXNwCl7B

Jun 17, 2021 · 4 likes · 4 shares · 31,380 followers View post →
Zach Brennan
@ZacharyBrennan · X

@AlecGaffney is the chart on the number of trials just active US? Worldwide numbers looks like a whole lot more https://t.co/m48JRCIucQ

Oct 1, 2019 · 11,007 followers View post →
Tyler J Ford
@TyFordFever · X

For those interested in the clinical landscape for #GeneTherapy - this article is super cool. It's from 2017, but it's interesting to look back at the 2012 version and see how things have changed (down w/ retro/plasmid/AdV up w/ AAV/lenti) https://t.co/T1hUfvp9jh

Mar 20, 2019 · 2 likes · 1,137 followers View post →
The Role Viral Vectors Play in Current Gene Therapy Development
News

2018 May;20(5):e3015. doi: 10.1002/jgm.3015. Epub 2018 Apr 19. Neukirch L, Kirkegaard Nielsen T, Laursen H, Daradoumis J, Thirion C, Holst PJ. Adenovirus ...

Dec 13, 2025 View →
Gene Therapy Clinical Trials Worldwide To 2017 An Update | PDF ...
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2018;20:e3015. wileyonlinelibrary.com/journal/jgm Copyright © 2018 John Wiley & Sons, Ltd. 1 of 16 https://doi.org/10.1002/jgm.3015 2 of 16 GINN ET AL. the ...

Dec 13, 2025 View →
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org/10.1002/jgm.3015 (3) State-of-the-art gene-based therapies: The road ahead. Nature Reviews Genetics - https://doi. org/10.1038/nrg2971 (4) Gene therapy ...

Dec 13, 2025 View →
Streamlining AAV Production for Gene Therapy | Technology Networks
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20(5) 2018: e3015; https://doi. org/10.1002/jgm.3015. 4 Lloyd I, et al. Pharma R&D Annual Review. Pharmaprojects: London, UK, February 2017 ...

Oct 4, 2024 View →
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org/10.1002/jgm.3015 (3) State-of-the-art gene-based therapies: The road ahead. Nature Reviews Genetics - https://doi. org/10.1038/nrg2971 ...

Sep 19, 2024 View →
Gene Therapy, DNA's Past, RNA's Future: A New Wave Of Hope
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2018;e3015. https://doi.org/ 10.1002/jgm.3015. In 2012, Glybera became the first-ever gene therapy approved in the European Union. This ...

Apr 11, 2024 View →
Exploring the Landscape of Gene Therapy | Pharmacy Times
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2018;20(5):e3015. doi:10.1002/jgm.3015. 4. Arabi F, Mansouri V, Ahmadbeigi N. Gene therapy clinical trials, where do we go? an overview ...

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Viral Clearance in AAV Purification: Case Study - BioProcess ...
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J. Gene Med. 20(5) 2018: e3015; https://doi.org/10.1002/jgm.3015.

Apr 16, 2021 View →
Opportunities and Challenges in Cell and Gene Therapy ...
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Ginn S et al, Gene therapy clinical trials worldwide to 2017: An update, Journal of Gene Medicine: doi.org/10.1002/jgm.3015, 2018. *(Article ...

Nov 1, 2019 View →
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5 (May 2018), https://onlinelibrary.wiley.com/doi/abs/10.1002/jgm.3015. [11] Center for Genetics and Society, "Human Germline Modification ...

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