iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications.

Jingxing Ou, John M Ball, Yizhao Luan, Tantai Zhao, Kiyoharu J Miyagishima, Yufeng Xu, Huizhi Zhou, Jinguo Chen, Dana K Merriman, Zhi Xie, Barbara S Mallon, Wei Li

May 2018

Synopsis of Social media discussions

Several posts demonstrate interest in the research's potential, such as referencing the unique cold adaptation mechanisms of ground squirrels and the prospects for biomedical advances. The tone conveys curiosity and optimism, with mentions of the publication offering 'new perspectives' and 'potential medical breakthroughs,' illustrating both enthusiasm and recognition of its broader impact.

A
Agreement
 Moderate agreement

Most discussions acknowledge the significance of the research, especially highlighting the potential medical benefits and the importance of understanding hibernation mechanisms.

I
Interest
 High level of interest

Posts express high interest, referencing specific details in the publication and emphasizing the novelty of using hibernator-derived iPSCs for medical applications.

E
Engagement
 Moderate level of engagement

Discussions include mentions of cellular pathways, species-specific adaptations, and potential translational research, indicating active engagement.

I
Impact
 Moderate level of impact

Participants suggest that this research could lead to major advances in medicine, such as improved organ preservation or new therapies for cold-related injuries.

Social Mentions

YouTube

2 Videos

Facebook

34 Posts

Twitter

3 Posts

TikTok

6 Posts

News

3 Articles

Metrics

Video Views

59

Total Likes

4

Extended Reach

2,344

Social Features

48

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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Hibernator-derived iPSCs for Cold Adaptation and Medical Research

Hibernator-derived iPSCs for Cold Adaptation and Medical Research

This video explains how stem cells from hibernating mammals, like ground squirrels, can help study cold tolerance and improve medical applications such as organ preservation and transplantation.

Ramon Chv

December 11, 2020

5 views

  • Rodrigo Maldonado
    @microsfeno (Twitter)

    RT @NicolasRohner: Wei Li @NIH Ground squirrel not only hibernate but they are one of the few mammals that have a cone dominated and cold a…
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    September 20, 2019

    1

  • Nicolas Rohner
    @NicolasRohner (Twitter)

    Wei Li @NIH Ground squirrel not only hibernate but they are one of the few mammals that have a cone dominated and cold adapted retina. Here is the paper: https://t.co/g7eaYZ1Pdl #nonstandard2019
    view full post

    September 20, 2019

    3

    1

  • T.H.
    @THmicroqbio (Twitter)

    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications https://t.co/Jh7fWDnv9t
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    February 20, 2019

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Abstract Synopsis

  • Hibernating mammals, like the 13-lined ground squirrel, can survive extremely low temperatures without cellular damage, presenting possible medical benefits.
  • Researchers identified key cellular pathways that help these mammals tolerate cold, particularly by comparing their stem cells to human ones.
  • Adjusting these cold resistance pathways in human cells and rat cells demonstrated improved cellular stability and could potentially enhance organ transplant preservation.