Cell Metab April 2018 PMID 29617642

The Science and Translation of Lactate Shuttle Theory.

George A Brooks

Mentions

98
Peak: 9 in Feb 2019
across 5 sources since Feb 2019

Extended reach

264,554
potential audience

Total likes

661

Video views

26,777

Mentions per month

Feb 2019 – Aug 2024

Where it's discussed

  • News44 articles
  • X / Twitter33 posts
  • Facebook11 posts
  • YouTube6 videos
  • Blogs4 articles

AI synopsis

What people are saying

The overall sentiment shows strong agreement with the publication, as many posts praise its comprehensive review and highlight how it challenges old beliefs about lactate, including references to Brooks' work and statements like 'lactate is now known to form continuously under aerobic conditions.' The tone often uses words like 'excellent,' 'wild,' and 'game changer,' which convey excitement and highlight its transformative impact on metabolic understanding.

AgreementStrong agreement

Most discussions emphasize the importance of the article, supporting the idea that lactate is a continuously produced and functional molecule, aligning with the article's main points.

InterestModerate interest

The posts show a moderate interest, with some expressing excitement about the topic being 'wild' or 'interesting,' but others mostly referencing the research summaries without deep enthusiasm.

EngagementHigh engagement

Many comments reference specific concepts, publications, and authors like George Brooks, indicating deep engagement and familiarity with the scientific discourse.

ImpactHigh impact

The discussions reflect recognition of a paradigm shift in understanding lactate, with users acknowledging its significant role in metabolism and signaling, thus highlighting high impact.

Abstract in brief

  • Lactate is recognized as a continuous byproduct of both anaerobic and aerobic metabolism, serving multiple crucial roles in the body.
  • It acts as a significant energy source, a precursor for gluconeogenesis (the creation of glucose), and plays a role in cell signaling through concepts known as the "lactate shuttle."
  • Elevated blood lactate levels, traditionally seen as a sign of stress during illness or injury, are now being understood as an indicator of strain and are being explored in clinical settings for their potential therapeutic benefits.

Top posts

Most liked on X and Bluesky
Bob Alejo
@Coach_Alejo · X

George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic metabolism lactate is now known to form continuously under aerobic conditions. 1-major energy source, 2-major gluconeogenic precursor, and 3-signaling molecule.

Feb 5, 2019 · 30 likes · 5 shares · 9,352 followers View post →
Robert Seaborne
@RobbySeaborne · X

@stevemagness @washingtonpost Not to mention that perhaps lactic acid/lactate isn’t as bad as first thought. Important review from Brooks recently, https://t.co/LF9Ze4VBiD

May 2, 2019 · 16 likes · 2 shares · 1,552 followers View post →
Gareth Sandford
@Gareth_Sandford · X

Full text: https://t.co/EBlck9KH6s

Jun 21, 2024 · 14 likes · 22,239 followers View post →
Power Lift Sports Science
@Power_LiftSport · X

From George Brooks' The Science and Translation of Lactate Shuttle Theory review: Once thought to be a waste product of anaerobic metabolism, lactate is now known to form continuously under aerobic conditions. Lactatemia seen as ‘‘strain’’ and not a ‘‘stress’’ biomarker to some

Feb 5, 2019 · 9 likes · 2 shares · 1,806 followers View post →
Felipe Isidro
@felipeisidro13 · X

En el músculo en reposo, la glucosa que ingresa a la célula pasa a piruvato y se transporta a las mitocondrias como acetil-CoA para su uso en el ciclo de Krebs. La glucosa que no está completamente oxidada entra en la glucólisis y produce lactato. https://t.co/ArZUEPLSnK

Nov 29, 2023 · 6 likes · 16,770 followers View post →
Soil Symbiont
@ainesanapulla · X

@no_earthquake Honestly just read this abstract, it lays out the basics https://t.co/FXfJPeha3X Also lactate in brain is wild https://t.co/bb0cFOqUnM

Aug 3, 2024 · 5 likes · 1 share · 209 followers View post →

All mentions

no earthquake (is back)
@no_earthquake · X

RT @ainesanapulla: @no_earthquake Honestly just read this abstract, it lays out the basics https://t.co/FXfJPeha3X Also lactate in brain i…

Aug 3, 2024 · 1 share · 10,378 followers View post →
Soil Symbiont
@ainesanapulla · X

@no_earthquake Honestly just read this abstract, it lays out the basics https://t.co/FXfJPeha3X Also lactate in brain is wild https://t.co/bb0cFOqUnM

Aug 3, 2024 · 5 likes · 1 share · 209 followers View post →
Gareth Sandford
@Gareth_Sandford · X

Full text: https://t.co/EBlck9KH6s

Jun 21, 2024 · 14 likes · 22,239 followers View post →
Mike Vivier
@MyEscape2022 · X

@drcourtneyhunt https://t.co/u2zy9jaJm8

Apr 27, 2024 · 642 followers View post →
Felipe Isidro
@felipeisidro13 · X

En el músculo en reposo, la glucosa que ingresa a la célula pasa a piruvato y se transporta a las mitocondrias como acetil-CoA para su uso en el ciclo de Krebs. La glucosa que no está completamente oxidada entra en la glucólisis y produce lactato. https://t.co/ArZUEPLSnK

Nov 29, 2023 · 6 likes · 16,770 followers View post →
Chris Masterjohn
@ChrisMasterjohn · X

@Mithreu @michaelmantzmd @RDValerie No that is not at all how lactate feeds neurons. Not at all. Something by Brooks on lactate shuttles might help you: https://t.co/XSX3i3Efnn

Jul 5, 2023 · 1 like · 68,638 followers View post →
Henning Wackerhage
@HeWaHippo · X

@Stew_CoachUK @GeorgeABrooks3 This is one of the many excellent reviews on lactate published by George Brooks https://t.co/a7mD2AX3k4

Jul 5, 2022 · 1 like · 3,955 followers View post →
Raúl Celdrán
@NTSAcademia · X

@AndyTurner132 Start with this

May 29, 2022 · 2 likes · 3,025 followers View post →
土橋祥平 Shohei Dobashi
@shoheidobashi · X

@sakuma33110207 同姓同名である可能性も否定できませんが、所属も名前も一致しているので、おそらくあの有名なBrooksだと思います。 https://t.co/CtKRmCP3Y5

Mar 7, 2022 · 1 like · 793 followers View post →
GaetYgoMad
@GaetYgoMad · X

@dr_a90zl @Trippin_0_ @ApresLaPub @Tanchouxx Brooks GA. The Science and Translation of Lactate Shuttle Theory. Cell Metab. 2018 Apr 3;27(4):757-785. doi: 10.1016/j.cmet.2018.03.008. PMID: 29617642.

Mar 1, 2022 · 398 followers View post →
Maxx Systems
@MaxxSystems · X

@ck_eternity_ https://t.co/WAIeis20Mj

May 1, 2021 · 1 like · 939 followers View post →
Deena Blacking
@DeenaBlacking · X

Closely followed by reading this in George Brooks' 2018 paper, The Science and Translation of Lactate Shuttle Theory: "An example of how loose usage of terminology leads to misunderstanding is illustrated by this (incorrect) Wikipedia entry [on fermentation]."

Oct 28, 2020 · 1 like · 437 followers View post →
Matías Monsalves-Álvarez
@profemonsalves · X

RT @D_Morales_Alamo: Completely agree... "The Science and Translation of Lactate Shuttle Theory" excellent review published by Prof. George…

Jul 18, 2020 · 2 shares · 1,511 followers View post →
Pablo Martínez
@ElretoMartinez · X

RT @D_Morales_Alamo: Completely agree... "The Science and Translation of Lactate Shuttle Theory" excellent review published by Prof. George…

Jul 18, 2020 · 2 shares · 376 followers View post →
Bryan Jasker PT, DPT
@oval_MetFlex · X

@JeroenSwart @TLexercise @iljukov Also see The Science and Translation of Lactate Shuttle Theory, Brooks, 2018. First paragraph: "lactate formed and utilized continuously in diverse cells under fully aerobic conditions"

Apr 3, 2020 · 609 followers View post →
Bob Poehling
@bobpoehling · X

Always love a good lactate paper. "O2 availability was classically considered to be a primary driver of lactate production, although there are numerous reasons to reconsider this simplistic view." The Science and Translation of Lactate Shuttle Theory https://t.co/svrLKHqTzc

Mar 2, 2020 · 204 followers View post →
Shaun Scott
@upyrbike · X

“The Science and Translation of Lactate Shuttle Theory” #lactateshuttle https://t.co/0BRdP3kmlf

Feb 25, 2020 · 2 likes · 1,437 followers View post →
Greg Grandgeorge
@T2MCoach · X

The Science and Translation of Lactate Shuttle Theory - ScienceDirect https://t.co/lVKVcb0gOh

Feb 3, 2020 · 257 followers View post →
Adrian Goate
@AquaAthleteSA · X

RT @RodrigoZacca: The Science and Translation of Lactate Shuttle Theory https://t.co/qncAdCN2KX

Sep 4, 2019 · 1 share · 155 followers View post →
Rodrigo Zacca
@RodrigoZacca · X

The Science and Translation of Lactate Shuttle Theory https://t.co/qncAdCN2KX

Sep 3, 2019 · 4 likes · 1 share · 1,717 followers View post →
Daniel Knebel
@DanielKnebel · X

Laktat hemmt die Leistung?

Aug 31, 2019 · 84 followers View post →
Ramzy Ross
@DrRamzyRoss · X

RT @RobbySeaborne: @stevemagness @washingtonpost Not to mention that perhaps lactic acid/lactate isn’t as bad as first thought. Important r…

May 3, 2019 · 2 shares · 1,279 followers View post →
Lopez-Grueso,R (PhD)
@LopezGrueso_R · X

RT @RobbySeaborne: @stevemagness @washingtonpost Not to mention that perhaps lactic acid/lactate isn’t as bad as first thought. Important r…

May 3, 2019 · 2 shares · 682 followers View post →
Robert Seaborne
@RobbySeaborne · X

@stevemagness @washingtonpost Not to mention that perhaps lactic acid/lactate isn’t as bad as first thought. Important review from Brooks recently, https://t.co/LF9Ze4VBiD

May 2, 2019 · 16 likes · 2 shares · 1,552 followers View post →
bkellylimerick@gmail.com
@brucelkelly · X

RT @Coach_Alejo: George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic meta…

Feb 6, 2019 · 5 shares · 323 followers View post →
Dave Champion
@davechampo · X

RT @Coach_Alejo: George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic meta…

Feb 6, 2019 · 5 shares · 833 followers View post →
Mike Young, PhD
@MikeYoung · X

RT @Coach_Alejo: George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic meta…

Feb 6, 2019 · 5 shares · 63,662 followers View post →
Coach P
@ChristianPolega · X

RT @Coach_Alejo: George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic meta…

Feb 5, 2019 · 5 shares · 685 followers View post →
Nick J. Siekirk, Ph.D., M.S., CSCS
@nsiekirk · X

RT @Coach_Alejo: George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic meta…

Feb 5, 2019 · 5 shares · 505 followers View post →
Coach Santiago
@kinescoach · X

RT @Power_LiftSport: From George Brooks' The Science and Translation of Lactate Shuttle Theory review: Once thought to be a waste product o…

Feb 5, 2019 · 2 shares · 55 followers View post →
Bob Alejo
@Coach_Alejo · X

George Brooks, The Science and Translation of Lactate Shuttle Theory: Once thought to be a waste product of anaerobic metabolism lactate is now known to form continuously under aerobic conditions. 1-major energy source, 2-major gluconeogenic precursor, and 3-signaling molecule.

Feb 5, 2019 · 30 likes · 5 shares · 9,352 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

RT @Power_LiftSport: From George Brooks' The Science and Translation of Lactate Shuttle Theory review: Once thought to be a waste product o…

Feb 5, 2019 · 2 shares · 22,172 followers View post →
Power Lift Sports Science
@Power_LiftSport · X

From George Brooks' The Science and Translation of Lactate Shuttle Theory review: Once thought to be a waste product of anaerobic metabolism, lactate is now known to form continuously under aerobic conditions. Lactatemia seen as ‘‘strain’’ and not a ‘‘stress’’ biomarker to some

Feb 5, 2019 · 9 likes · 2 shares · 1,806 followers View post →