Commençons donc. Premier intervenant à la barre "Morgane Levine" qui propose un test nommé "Horvath-Levine"... Il s'appuie sur une publication qu'elle a faite sous la direction de Steve Horvath : https://t.co/hYo0MYn31M ⬇️ https://t.co/rHeXEtTcYr
An epigenetic biomarker of aging for lifespan and healthspan.
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Jan 2019 – Jun 2026Where it's discussed
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Several discussions highlight the novel insights provided by the DNAm PhenoAge biomarker compared to past markers, with terms like 'outperforms' and 'strong correlation' being commonly mentioned. Additionally, phrases such as 'important 2018 paper' and references to specific blood tests enhance the discourse by applying a sense of urgency and highlighting the clinical relevance, indicating that contributors are both informed and engaged with the research.
Many discussions show general support for the findings of the paper, indicating respect for its contributions.
The tone reflects strong curiosity around the implications of the new biomarker, highlighting its significance in understanding aging.
There are references to detailed aspects of the methodology and comparisons to previous biomarkers, showing a moderate level of engagement.
Participants express that this publication could greatly influence future research and practical applications in the field of aging.
Abstract in brief
- The study identifies a new epigenetic biomarker of aging called DNAm PhenoAge, which is more effective than previous markers in predicting aging-related outcomes like mortality, cancer, and Alzheimer's disease.
- This biomarker incorporates clinical measures of phenotypic age alongside chronological age, enabling a more comprehensive understanding of biological aging.
- It is linked to specific biological pathways, such as proinflammatory responses and mitochondrial function, suggesting that it can reveal significant insights into the mechanisms of aging across various tissues.
Top posts
Most liked on X and Bluesky#2 Scientific Tweet for @BioProtocol and @Aubrai_ "An epigenetic biomarker of aging for lifespan and healthspan" - DNAm PhenoAge, a DNA methylation (DNAm)-based biomarker that outperforms nearly all previous measures (Horvath, Hannum) in predicting morbidity and mortality https://t.co/MxwjBhIqHQ https://t.co/MWb41hlybM
Proud to have our paper on CUDC-907 as a new senolytic as one of @AgingJrnl's Top 10 Papers in 2023 https://t.co/4WPb3WuQlh
An epigenetic biomarker of aging for lifespan and healthspan (2018) https://t.co/gHH7SSbjha
@foundmyfitness GrimmAge esp. (Horvath pub) shows promise: https://t.co/1o2JVX1nF3 but the best clock will depend on precisely what this surrogate variable is targeting. @DrMorganLevine is doing some great comparative work here as well: https://t.co/yg4kslhS9C https://t.co/gHH7SSbjha -@agingdoc1
Join us daily as we count down the 10 most popular Aging papers in 2023 (based on Crossref resolutions). #2023YearinReview #2: "An epigenetic biomarker of aging for lifespan and healthspan" DOI: https://t.co/xYPTdJ83Qw https://t.co/1JpCQ30QyN
All mentions
Innovative Aging Clocks: Understanding Biological Age Measurement
In this video, we will discuss aging clocks, which measure not just chronological age but biological age derived from various biomarkers. We will explore methods like the BiT age clock that enhance accuracy in…
Understanding the DNAm PhenoAge Biomarker for Health and Longevity
This video explores a new epigenetic biomarker of aging known as DNAm PhenoAge. It surpasses previous markers in predicting age-related outcomes such as mortality, cancer, and Alzheimer's disease, linking biological…
DNA Methylation GrimAge Predicts Lifespan and Age-Related Health Risks
Dr. Steve Horvath revisits key research on DNA methylation and aging, highlighting how DNAm GrimAge predicts lifespan and healthspan. The biomarker outperforms other clocks in assessing risks of death, heart disease…
El Reloj Epigenético: Dos Edades, una que no miente
Overview of the epigenetic clock predicting biological age from DNA methylation. Historical development, clocks PhenoAge and GrimAge, and a small 8-week study showing lifestyle changes may modestly lower clock readings.
O Relojo Epigenético: Duas Idades, Uma que Não Mente
Explains the epigenetic clock estimating biological age from DNA methylation. Covers Horvath clock origins, PhenoAge and GrimAge, plus a small trial where lifestyle changes reduced the clock reading.
El Reloj Epigenético: Dos Edades, y una No Miente
Describes epigenetic clock based on DNA methylation; Horvath clock and subsequent models PhenoAge/GrimAge. Highlights a small trial where diet, sleep, exercise, and relaxation lowered clock readings.
Metformin's Potential Role in Aging and Longevity Mechanisms
This study explores how metformin may influence aging and lifespan through changes in DNA methylation, an epigenetic process. DNA methylation data from patients suggests links to longevity, AMPK, and inflammation…
Psychological Factors Significantly Influence Biological Aging in Older Adults
Psychological factors such as loneliness and unhappiness contribute up to 1.65 years to biological age, highlighting their role alongside physical health in the aging process. The study uses deep learning to measure…
The Epigenetic Clock: You Have Two Ages, and One Lies
Overview of DNA methylation clocks, Horvath’s clock and newer models predicting lifespan. Includes a small trial where lifestyle changes lowered clock readings and calls for larger studies, plus a landmark mouse…
#2 Scientific Tweet for @BioProtocol and @Aubrai_ "An epigenetic biomarker of aging for lifespan and healthspan" - DNAm PhenoAge, a DNA methylation (DNAm)-based biomarker that outperforms nearly all previous measures (Horvath, Hannum) in predicting morbidity and mortality https://t.co/MxwjBhIqHQ https://t.co/MWb41hlybM
2.Levine M. et al. (2018). “An epigenetic biomarker of aging for lifespan and healthspan.” Aging (Albany NY). ・血中DNAメチル化に基づく新たな老化指標「DNAm PhenoAge」を開発した研究(第2世代エピジェネティッククロック)。 https://t.co/tyH2MOspXa
An epigenetic biomarker of aging for lifespan and healthspan - PMC https://t.co/5yFv2IIT52
its based on a paper from 2018 where they found strong correlation between these standard markers and all cause mortality. paper -> https://t.co/9FijKbP82q
RT @hernangraffe: https://t.co/EtX99cWdil
https://t.co/EtX99cWdil
RT @gglinskii: An epigenetic biomarker of aging for lifespan and healthspan https://t.co/WX95Jz5ZcG
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/WX95Jz5ZcG
Proud to have our paper on CUDC-907 as a new senolytic as one of @AgingJrnl's Top 10 Papers in 2023 https://t.co/4WPb3WuQlh
Watch an #agingshort video of Aging's top 10 #papers in 2023, based on the number of times a DOI is successfully resolved (Crossref data). https://t.co/D6XfiHlBQZ #aging #oa #research #publication #lifespan #healthspan #gerontology #longevity #countdown #list #top10 #youtube
RT @AgingJrnl: Join us daily as we count down the 10 most popular Aging papers in 2023 (based on Crossref resolutions). #2023YearinReview…
RT @AgingJrnl: Join us daily as we count down the 10 most popular Aging papers in 2023 (based on Crossref resolutions). #2023YearinReview…
RT @AgingJrnl: Join us daily as we count down the 10 most popular Aging papers in 2023 (based on Crossref resolutions). #2023YearinReview…
Join us daily as we count down the 10 most popular Aging papers in 2023 (based on Crossref resolutions). #2023YearinReview #2: "An epigenetic biomarker of aging for lifespan and healthspan" DOI: https://t.co/xYPTdJ83Qw https://t.co/1JpCQ30QyN
RT @AlexSamTG: Commençons donc. Premier intervenant à la barre "Morgane Levine" qui propose un test nommé "Horvath-Levine"... Il s'appuie s…
RT @hernangraffe: https://t.co/EtX99cVFsN
https://t.co/EtX99cVFsN
RT @agingdoc1: Obviously there are tradeoffs WRT predictive value vs. other desirable aging biomarker attributes
RT @agingdoc1: Obviously there are tradeoffs WRT predictive value vs. other desirable aging biomarker attributes
Obviously there are tradeoffs WRT predictive value vs. other desirable aging biomarker attributes
Papers reporting each of the clocks are here: https://t.co/81qRT9HD23 https://t.co/twaRXLdCiX https://t.co/39AYUr8VV8
I’ve seen this ‘focus on a single measure’ in some biohackers. eg @DrMorganLevine et al. made this clock by finding blood tests that predict biological age first. This means you can calculate your bio age just with (fairly standard) test results… https://t.co/M3xEu9QK7J
"An epigenetic biomarker of aging for lifespan and healthspan" Important 2018 paper by @DrMorganLevine & colleagues in @AgingJrnl https://t.co/CJIdtm8wfH #aging https://t.co/cWfIFcM4WY
RT @AlexSamTG: Commençons donc. Premier intervenant à la barre "Morgane Levine" qui propose un test nommé "Horvath-Levine"... Il s'appuie s…
RT @AlexSamTG: Commençons donc. Premier intervenant à la barre "Morgane Levine" qui propose un test nommé "Horvath-Levine"... Il s'appuie s…
Commençons donc. Premier intervenant à la barre "Morgane Levine" qui propose un test nommé "Horvath-Levine"... Il s'appuie sur une publication qu'elle a faite sous la direction de Steve Horvath : https://t.co/hYo0MYn31M ⬇️ https://t.co/rHeXEtTcYr
https://t.co/coXb4W3DdW
RT @ZaneKoch6: Biological clocks, a la PhenoAge (@DrMorganLevine) and GrimAge, are more accurate predictors of age-related deterioration a…
Biological clocks, a la PhenoAge (@DrMorganLevine) and GrimAge, are more accurate predictors of age-related deterioration and offer more interpretable predictions. For clinical applications these are the way forward. phenoAge: 10.18632/aging.101414 grimAge: 10.18632/aging.101684
9 blood measures to estimate biological age https://t.co/tiPT6JP2Q1 https://t.co/IWa4vZL1sB https://t.co/aEu9PiLr9z https://t.co/yTM6dWPE1u
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/CZ1l3QdzSn
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/vHCkLETw8e
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/y5rG3LpaDl
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/mnoQpQLlrR
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/PssIUO5EAb
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/Dpm37hdGa1
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/RYyQocqxq5
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/Voly097Q6z
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/KZjoaXSGuY
RT @agingdoc1: An epigenetic biomarker of aging for lifespan and healthspan (2018) https://t.co/gHH7SSbjha
RT @agingdoc1: An epigenetic biomarker of aging for lifespan and healthspan (2018) https://t.co/gHH7SSbjha
RT @agingdoc1: An epigenetic biomarker of aging for lifespan and healthspan (2018) https://t.co/gHH7SSbjha
An epigenetic biomarker of aging for lifespan and healthspan (2018) https://t.co/gHH7SSbjha
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/Qslf2JQpMo
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/uV4aiNXJR3
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/jThIYUpvcM
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/hXkRLpJBFx
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/RflQ5VenMW
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/jgFdf4Jwpv
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/XmxXikZs4N
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/gsnuIaeLAk
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/shVneMh231
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/zEFNlBhNmq
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/OqUddNQ4d3
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/U6wsiJnQWH
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/oa4JgQOe8N
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/1SNfFKexaE
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/GnmgIaT4Z3
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/b1TK4EtjU2
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/JzkFeDTwBE
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/gDpwRrPaqF
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/eFgbJMf5UW
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/rfWojlu3cg
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/SgPcIcFNRJ
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/a44Sz5UqPM
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/PmDR33X4hi
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/pu5YvBAbEA
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An epigenetic biomarker of aging for lifespan and healthspan https://t.co/bXCvIPEW3N
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@Alex_HPL @davidasinclair @DrAdamBat @DrCaseysKitchen @hubermanlab @PeterAttiaMD @agingdoc1 Big fan of Steve Horvath’s work on epigenetic aging https://t.co/7tYI3z8AQR
@elonmusk Suggested changes to your tweet, Elon: Let’s set a (biological) age limit after which you can’t run for political office, perhaps a number just below (62). Ref: An epigenetic biomarker of aging for lifespan and healthspan Aging (Albany NY). April 17, 2018. https://t.co/sLuUV8IJ7S
@richcollins @mike_lustgarten CMP + CBC + hsCRP, based on "An epigenetic biomarker of aging for lifespan and healthspan", Aging (Albany NY) 10(4) 573-591 (2018 Apr 18).
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/aUApRZsogQ
@Jess67335463 @davidasinclair Here's the paper from Morgan Levine An epigenetic biomarker of aging for lifespan and healthspan https://t.co/pnZ3PS77CY Ageless RX calculator is based on this.
Envejecimiento | Un biomarcador epigenético del envejecimiento para la vida y la esperanza de salud - Texto Completo https://t.co/5CHi9gAm0y
Very cool, epigenetic biomarkers of Aging: https://t.co/z8q2lQ5xX0
RT @agingdoc1: @foundmyfitness GrimmAge esp. (Horvath pub) shows promise: https://t.co/1o2JVX1nF3 but the best clock will depend on precise…
@foundmyfitness GrimmAge esp. (Horvath pub) shows promise: https://t.co/1o2JVX1nF3 but the best clock will depend on precisely what this surrogate variable is targeting. @DrMorganLevine is doing some great comparative work here as well: https://t.co/yg4kslhS9C https://t.co/gHH7SSbjha -@agingdoc1
@GuruAnaerobic 100%, but there are far better approaches An epigenetic biomarker of aging for lifespan and healthspan https://t.co/WDb8L7G67r
An epigenetic biomarker of aging for lifespan and healthspan https://t.co/5I4E1DjhV6
RT @biorxiv_pubd: An epigenetic biomarker of aging for lifespan and healthspan published as: https://t.co/3sRTrPm2vO @AgingJrnl #biorxiv
RT @biorxiv_pubd: An epigenetic biomarker of aging for lifespan and healthspan published as: https://t.co/3sRTrPm2vO @AgingJrnl #biorxiv
An epigenetic biomarker of aging for lifespan and healthspan published as: https://t.co/3sRTrPm2vO @AgingJrnl #biorxiv
RT @LifeboatHQ: Morgan E. Levine, coauthor of “An epigenetic biomarker of aging for lifespan and healthspan”, joins our Life Extension Boar…
Morgan E. Levine, coauthor of “An epigenetic biomarker of aging for lifespan and healthspan”, joins our Life Extension Board. https://t.co/rljMWzhWQ6 https://t.co/Z0VRpwXh7Z
Chcesz wiedzieć w jakim tempie starzeje się Twój organizm? Zapytaj genetyka. Analiza 513 cytozyn w genomie człowieka daje precyzyjną informację o tempie starzenia się organizmu i tak zwanym wieku fenotypowym. https://t.co/aouM8LDAer
An epigenetic biomarker of aging for lifespan and healthspan. - PubMed - NCBI https://t.co/IzHIRSTAMH
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