PubHawk
April 2018 PMID 29695481

Anticholinergic drugs and risk of dementia: case-control study.

Kathryn Richardson, Chris Fox, Ian Maidment, Nicholas Steel, Yoon K Loke, Antony Arthur, Phyo K Myint, Carlota M Grossi, Katharina Mattishent, Kathleen Bennett, Noll L Campbell, Malaz Boustani, Louise Robinson, Carol Brayne, Fiona E Matthews

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Mentions

142
Peak: 3 in Jun 2019
across 7 sources since Apr 2018

Extended reach

168,647
potential audience

Total likes

12

Video views

1,388

Mentions per month

Apr 2018 – Jul 2025

Where it's discussed

  • News64 articles
  • Facebook42 posts
  • Blogs16 articles
  • X / Twitter14 posts
  • Reddit3 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Many posts express agreement by referencing other studies and emphasizing the significance of long-term risks, such as one user mentioning risk factors identified '15-20 years before dementia symptoms.' The tone ranges from supportive to analytical, with detailed references to research methods and implications, indicating both high interest and meaningful engagement.

AgreementModerate agreement

Many discussions show support for the study’s findings, referencing other research that confirms the risks associated with anticholinergic drugs, indicating general agreement.

InterestHigh interest

Posts display a high level of curiosity, with users actively discussing various aspects of the research, including drug classes and timing of use, reflecting strong interest.

EngagementModerate engagement

Some posts delve into specifics, citing related studies and debating implications, showing deeper engagement beyond surface-level reactions.

ImpactModerate impact

The discussions highlight the potential influence of this research on medical practice and public awareness, suggesting it could inform both policy and individual decisions.

Abstract in brief

  • This study analyzed how different levels and durations of anticholinergic drug use are linked to the risk of developing dementia, finding a significant association especially with antidepressants, urological, and antiparkinson drugs with high anticholinergic activity.
  • The research involved a large number of UK patients and controls from the Clinical Practice Research Datalink, comparing those diagnosed with dementia to those without, with exposure assessed up to 20 years before diagnosis.
  • Results suggest that increased use of certain anticholinergic drugs may raise dementia risk, but further studies are needed to see if this is due to the drugs causing early dementia symptoms or other factors specific to certain drug classes.
Read the full abstract

Top posts

Most liked on X and Bluesky
Graham Stretch
@GrahamStretch · X

Interesting responses:I wouldn’t say ‘mixed’ https://t.co/polB9QJq3O Evidence of risk with ACB drugs used ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (Richardson, @maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’, score not dose https://t.co/iXOGCgPjQI

Apr 26, 2022 · 3 likes · 1 share · 9,222 followers View post →
Agingdoc
@agingdoc1 · X

Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults https://t.co/NSQ6PWFxpc & Anticholinergic drugs and risk of dementia: case-control study https://t.co/FTdtAnbl30 * Meclizine

Jul 8, 2022 · 1 like · 1 share · 42,542 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults https://…

Jul 8, 2022 · 1 share · 42,542 followers View post →
Agingdoc
@agingdoc1 · X

Anticholinergic drugs and risk of dementia: case-control study (pdf RT) https://t.co/0QNYiQRsNS

Jul 8, 2022 · 42,542 followers View post →
Graham Stretch
@GrahamStretch · X

@p3pharmacy Interesting responses: I wouldn’t say ‘mixed’… Evidence of risk with ACB drugs used in ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (@maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’,score not dose https://t.co/ffIWlRVllF https://t.co/krRHlBHmkh

Apr 26, 2022 · 9,222 followers View post →
Graham Stretch
@GrahamStretch · X

Interesting responses:I wouldn’t say ‘mixed’ @p3pharmacy … Evidence of risk with ACB drugs used ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (Richardson, @maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’, score (ACB 3) not dose https://t.co/RMWNjjRXK7 https://t.co/PkJiMNUKPk

Apr 26, 2022 · 9,222 followers View post →

All mentions

Agingdoc
@agingdoc1 · X

Anticholinergic drugs and risk of dementia: case-control study (pdf RT) https://t.co/0QNYiQRsNS

Jul 8, 2022 · 42,542 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults https://…

Jul 8, 2022 · 1 share · 42,542 followers View post →
Agingdoc
@agingdoc1 · X

Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults https://t.co/NSQ6PWFxpc & Anticholinergic drugs and risk of dementia: case-control study https://t.co/FTdtAnbl30 * Meclizine

Jul 8, 2022 · 1 like · 1 share · 42,542 followers View post →
Graham Stretch
@GrahamStretch · X

Interesting responses:I wouldn’t say ‘mixed’ @p3pharmacy … Evidence of risk with ACB drugs used ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (Richardson, @maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’, score (ACB 3) not dose https://t.co/RMWNjjRXK7 https://t.co/PkJiMNUKPk

Apr 26, 2022 · 9,222 followers View post →
Graham Stretch
@GrahamStretch · X

@p3pharmacy Interesting responses: I wouldn’t say ‘mixed’… Evidence of risk with ACB drugs used in ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (@maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’,score not dose https://t.co/ffIWlRVllF https://t.co/krRHlBHmkh

Apr 26, 2022 · 9,222 followers View post →
Graham Stretch
@GrahamStretch · X

Interesting responses:I wouldn’t say ‘mixed’ https://t.co/polB9QJq3O Evidence of risk with ACB drugs used ‘midlife’ (Chuang et al doi:10.1016/j.trci.2017.06.004) & 15-20yr before dementia Sx (Richardson, @maidment_dr et al doi:10.1136/bmj.k1315) - not ‘elderly’, score not dose https://t.co/iXOGCgPjQI

Apr 26, 2022 · 3 likes · 1 share · 9,222 followers View post →
Aia May
@AiaMay3 · X

@Moonrise1014 @benzosarebad @Wigglyworm8 @kennedy6110 @SameiHuda @lareinedejade @RealJesseLuke https://t.co/f2QaJR4Z7d https://t.co/DBPJXAcn0n https://t.co/8S59nYfi0G you can look up the rest yourself.

Jun 12, 2020 · 49 followers View post →
MedsOptADRD
@MedsOptADRD · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/eRStZwUH28

Sep 8, 2019 · 99 followers View post →
ボソすば
@BoSoBoSoSan · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/mqou0GBy9Q

Aug 15, 2019 · 225 followers View post →
Leah Hansen
@hansen_leah · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/Ni5P4L4lnY

Jul 19, 2019 · 158 followers View post →
♦️Tonya Tanner♦️
@ArkDiamond · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/gelMwNARET

Jun 29, 2019 · 714 followers View post →
Teri (she/her)
@teriwishart · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/Guvl8suRHM

Jun 25, 2019 · 291 followers View post →
BattlefieldsOfHlywd
@BattlefieldHlwd · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/lov3yC6UET

Jun 24, 2019 · 6,093 followers View post →
Sean Ninan
@sean9n · X

Anticholinergic drugs and risk of dementia: case-control study https://t.co/Aei2tUBIxO

May 28, 2019 · 4,333 followers View post →
Yasser Ad-Dab'bagh ياسر الدباغ
@yasseraddabbagh.bsky.social · Bluesky

Anticholinergic drugs and risk of dementia: case-control study https://www.bmj.com/content/361/bmj.k1315

Apr 28, 2018 View post →