A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice.

Haixia Yang, Weicang Wang, Kymberleigh A Romano, Min Gu, Katherine Z Sanidad, Daeyoung Kim, Jun Yang, Birgitta Schmidt, Dipak Panigrahy, Ruisong Pei, Derek A Martin, E Ilker Ozay, Yuxin Wang, Mingyue Song, Bradley W Bolling

May 2018 Sci Transl Med

Synopsis of Social media discussions

Most discussions express concern about the health risks associated with antimicrobial additives, citing the study’s findings about increased inflammation and tumors. The tone and choice of words like 'danger' and 'warning' underscore a sense of urgency and impact, reflecting a collective interest in the implications for human health and safety regulations.

A
Agreement
 Moderate agreement

Many discussions highlight concerns about antimicrobial additives' negative effects, showing general agreement on the study's importance.

I
Interest
 Moderate level of interest

Posts show moderate interest, often questioning or warning about health implications related to antimicrobial use.

E
Engagement
 Moderate level of engagement

Several discussions reference specific details about gut health and microbiota, indicating engagement with the topic.

I
Impact
 Moderate level of impact

The conversations emphasize potential health risks and regulatory concerns, suggesting a perceived moderate to high impact.

Social Mentions

YouTube

3 Videos

Facebook

11 Posts

Twitter

17 Posts

Blogs

4 Articles

News

100 Articles

Reddit

2 Posts

Metrics

Video Views

88,733

Total Likes

2,021

Extended Reach

112,321

Social Features

137

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Impact of Antimicrobial Additives on Colonic Inflammation and Cancer Risk

Impact of Antimicrobial Additives on Colonic Inflammation and Cancer Risk

Triclosan, a common antimicrobial in consumer products, can cause low-grade colonic inflammation, worsen colitis, and increase colon tumor risk in mice. It alters gut microbiota and activates TLR4 signaling, suggesting potential human health risks.

うわさのゆっくり解説【18時30更新】

September 16, 2022

87,639 views

Triclosan's Impact on Gut Health and Disease Risk

Triclosan's Impact on Gut Health and Disease Risk

Triclosan, a common antimicrobial found in consumer products, can cause low-grade inflammation in the colon, worsen colitis, and increase colon tumor risk in mice. This highlights potential health concerns and the need for regulatory reassessment.

Daniel Rizzo

December 27, 2023

899 views

Impact of Triclosan on Colonic Inflammation and Cancer Risk

Impact of Triclosan on Colonic Inflammation and Cancer Risk

A common antimicrobial additive increases colonic inflammation and colon tumorigenesis in mice. Triclosan exposure causes low-grade inflammation, alters gut microbiota, and activates inflammatory pathways, potentially raising colon cancer risk in humans.

Guodong Zhang

May 31, 2018

195 views

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Abstract Synopsis

  • Triclosan (TCS), a common antimicrobial found in many consumer products, can cause low-grade inflammation in the colon, worsen colitis, and increase the risk of colon tumors in mice.
  • TCS exposure leads to changes in gut microbiota and activates TLR4 signaling, which contributes to inflammation; these effects are lessened in germ-free mice, indicating the microbiota's role.
  • The study suggests that TCS may negatively impact human health by promoting intestinal inflammation and cancer risk, calling for a reevaluation of its safety regulations.]