July 2018 PMID 29852083

Endogenous and Exogenous Opioids in Pain.

Gregory Corder, Daniel C Castro, Michael R Bruchas, Grégory Scherrer

Mentions

20
Peak: 3 in Jan 2021
across 3 sources since Nov 2018

Extended reach

669,328
potential audience

Total likes

5,465

Video views

655,641

Mentions per month

Nov 2018 – Aug 2025

Where it's discussed

  • X / Twitter12 posts
  • YouTube5 videos
  • Facebook3 posts

AI synopsis

What people are saying

The social discussions highlight the significance of the article by sharing informative videos and promoting upcoming talks, using words like 'brilliant' and 'get informed,' which reflect enthusiasm and recognition of its educational impact. The tone and brevity aim to inform rather than critique, supporting a moderate engagement level and recognition of its relevance to pain management and neuroscience.

AgreementModerate agreement

Most discussions acknowledge the importance of understanding opioid mechanisms, showing general support for the article's focus.

InterestHigh interest

The discussions display high interest, especially with mentions of videos explaining the neuroscience and upcoming talks on pain interventions.

EngagementModerate engagement

Engagement is moderate; posts include sharing videos and brief reviews, but lack deep analytical discussions.

ImpactModerate impact

The discussions suggest the publication has some influence, especially in informing viewers about neuroscience and pain management, though direct clinical implications are not fully explored.

Abstract in brief

  • Opioids, which are key for treating severe pain, act on the body's endogenous opioid system involving specific receptors and peptides, but their use is now scrutinized due to abuse and overdose concerns.
  • The review covers the organization and pharmacology of this system, detailing how opioids influence neuronal function and neurotransmission through signaling mechanisms.
  • It also explores where opioids exert their pain-relieving effects along peripheral and central pathways, highlighting their role in reducing both the sensory and emotional aspects of pain.]

Top posts

Most liked on X and Bluesky
LePubScientifique
@LePubScientifiq · X

A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to interventions for pain relief & opioid reduction at #lepub next Weds - come & join us Endogenous and Exogenous Opioids in Pain https://t.co/jGySrCjaRe #opioids #pain

Jan 14, 2021 · 5 likes · 2 shares · 2,236 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/WR07JmLteh

Feb 19, 2022 · 1 like · 86 followers View post →
Laura Rathbone
@laurarathbone · X

RT @LePubScientifiq: A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to intervent…

Jan 14, 2021 · 2 shares · 4,221 followers View post →
Dr. Daniel Castro
@FlanBrain · X

RT @FlyBottleEscape: Happy to share the open e-print of our @AnnualReviews Neuroscience article, Endogenous and Exogenous Opioids in Pain.…

Jul 3, 2023 · 33 shares · 3,618 followers View post →
Rosaura Brisuela @roswitta.bsky.social
@Roswitamind · X

Endogenous and Exogenous Opioids in Pain:https://t.co/9dnIhRNfT6 https://t.co/tOiKRpEQ2w

Jun 26, 2019 · 1,284 followers View post →
Niki
@Fizzbw · X

RT @LePubScientifiq: A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to intervent…

Jan 14, 2021 · 2 shares · 1,255 followers View post →

All mentions

Dr. Daniel Castro
@FlanBrain · X

RT @FlyBottleEscape: Happy to share the open e-print of our @AnnualReviews Neuroscience article, Endogenous and Exogenous Opioids in Pain.…

Jul 3, 2023 · 33 shares · 3,618 followers View post →
Dan Christoffel
@DoctorDanPhD · X

RT @FlyBottleEscape: Happy to share the open e-print of our @AnnualReviews Neuroscience article, Endogenous and Exogenous Opioids in Pain.…

Jul 3, 2023 · 33 shares · 495 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/ColJjql34p

Mar 31, 2022 · 86 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/WR07JmLteh

Feb 19, 2022 · 1 like · 86 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/3UYjOwYIAj

Feb 15, 2022 · 86 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/6TUISkqWWT

Jan 30, 2022 · 86 followers View post →
Safe Rx Mendocino
@SafeRxMendocino · X

Here is a two minute video on the Neuroscience of Opioids #Mendocino #Overcomingaddiction https://t.co/1QsVxndOiB https://t.co/m4p9KaVg9w

Dec 15, 2021 · 86 followers View post →
Laura Rathbone
@laurarathbone · X

RT @LePubScientifiq: A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to intervent…

Jan 14, 2021 · 2 shares · 4,221 followers View post →
Niki
@Fizzbw · X

RT @LePubScientifiq: A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to intervent…

Jan 14, 2021 · 2 shares · 1,255 followers View post →
LePubScientifique
@LePubScientifiq · X

A brief review to get informed before listening to the brilliant @BethDarnall talk about improving access to interventions for pain relief & opioid reduction at #lepub next Weds - come & join us Endogenous and Exogenous Opioids in Pain https://t.co/jGySrCjaRe #opioids #pain

Jan 14, 2021 · 5 likes · 2 shares · 2,236 followers View post →
ken
@ken_______7 · X

https://t.co/oJsVx08d8d

Jan 1, 2020 · 6 followers View post →
Rosaura Brisuela @roswitta.bsky.social
@Roswitamind · X

Endogenous and Exogenous Opioids in Pain:https://t.co/9dnIhRNfT6 https://t.co/tOiKRpEQ2w

Jun 26, 2019 · 1,284 followers View post →