October 2018 PMID 29909109

Effects of Statins on Coronary Atherosclerotic Plaques: The PARADIGM Study.

Sang-Eun Lee, Hyuk-Jae Chang, Ji Min Sung, Hyung-Bok Park, Ran Heo, Asim Rizvi, Fay Y Lin, Amit Kumar, Martin Hadamitzky, Yong Jin Kim, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J Budoff, Ilan Gottlieb

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Mentions

Peak: 2 in Dec 2023

across 4 sources since Sep 2020

Extended reach

69,221

potential audience

Total likes

1,011

Video views

25,434

Mentions per month

Sep 2020 – May 2025

Where it's discussed

X / Twitter5 posts
Facebook5 posts
News5 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions show high interest by referencing specific research articles and authors, such as Lee et al., and express moderate engagement through comments about the study’s implications for plaque stabilization and heart disease prevention, using precise terminology and emphasizing the study's clinical relevance.

AgreementModerate agreement

Most discussions recognize the positive findings of the study, indicating general support for the conclusions about statins' effects.

InterestHigh interest

The posts express high interest, referencing specific studies, authors, and clinical implications, showing engagement with the research details.

EngagementModerate engagement

Some posters cite the article directly with comments on its significance, reflecting a moderate level of detailed engagement.

ImpactModerate impact

Although the discussion emphasizes the importance of the study, it remains mostly within academic and clinical contexts without discussing broader societal implications.

Abstract in brief

This study investigated how statins affect the growth and characteristics of coronary artery plaques in patients without prior heart disease, showing that statins slow down the overall buildup of atherosclerosis and reduce the development of high-risk plaques.
Patients taking statins experienced a slower increase in the overall plaque volume but a faster increase in calcified plaques, indicating that statins might promote plaque stabilization by encouraging calcification.
Overall, statins were linked to a significant reduction in the progression of dangerous plaques, suggesting they help reduce the risk of future heart problems by altering plaque composition and growth.

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All mentions

Understanding Heart Disease and Plaque Risks in Coronary Artery Disease

Join Dr. McDougall as he explains heart disease, ruptured volatile plaque, and their risks, supported by insights from the SCOT-HEART study on plaque features and adverse heart events.

Dr. McDougall Health & Medical Center · Dec 4, 2023 16,341 views

Understanding Heart Disease Risks and the Hidden Dangers of Plaque Rupture

Join Dr. McDougall as he explains heart diseases, particularly the risks associated with volatile plaque rupture and how specific plaque features can predict adverse heart events over five years.

Dr. McDougall Health & Medical Center · Dec 9, 2023 9,093 views

Steven Kaplan

@ROIdude · X

@Barrington47875 @ValerieAnne1970 https://t.co/AMPqLfCrGF? https://t.co/qzp1dLo9rl https://t.co/kBOVvQPbH6

May 3, 2025 · 6,134 followers View post →

Casey

@Casey9275883939 · X

@crazieyfox @DrNadolsky There are numerous studies that prove statins prevent heart disease. The internet will help you find them but here you go https://t.co/FGmdrwc5Z3.

Apr 12, 2025 · 1 like · 4 followers View post →

Austin Dudzinski, PharmD, BCACP

@ApoDudz · X

@vintage_worlds https://t.co/FHjNwFevtg https://t.co/5wpruvXYhd

Feb 24, 2025 · 1 like · 985 followers View post →

Dr. Ozan Ünlü

@DrOzanUnlu · X

May 6, 2024 · 4 likes · 36,623 followers View post →

LARABA Chafik

@ChafikLaraba · X

@SBRInvestor @ISeropianMD @DLBHATTMD @RonBlankstein @BudoffMd @Heart_SCCT Interesting paper for statin effect seen by CCTA : Lee S-E, Chang H-J, Sung JM, et al. Effects of statins on coronary atherosclerotic plaques: the PARADIGM study. J Am Coll Cardiol Img 2018;11:1475–84.

Sep 14, 2020 · 41 followers View post →