Senolytics improve physical function and increase lifespan in old age.

Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser, Jennifer L Onken, Kurt O Johnson, Grace C Verzosa, Larissa G P Langhi, Moritz Weigl

August 2018

Synopsis of Social media discussions

The collective discussions highlight key findings, like the 36% lifespan increase in mice treated with senolytics, and cite specific studies and mechanisms, often using precise terminology and referencing multiple trials, which reflects high engagement and perceived importance of the research.

A
Agreement
 Moderate agreement

Most discussions support the findings that senolytics, like dasatinib and quercetin, can improve health span and extend lifespan, with many emphasizing positive results such as a 36% increase in survival.

I
Interest
 High level of interest

Posts show high engagement, referencing specific studies, molecular pathways, and potential applications, indicating strong curiosity about aging interventions.

E
Engagement
 High engagement

Discussions include detailed references to experimental data, potential risks, and broader implications, demonstrating deep involvement with the research content.

I
Impact
 High level of impact

The prominent focus on lifespan extension and health improvements suggests these findings could influence future aging research and potential therapies, implying significant impact.

Social Mentions

YouTube

4 Videos

Bluesky

1 Posts

Facebook

17 Posts

Twitter

167 Posts

Blogs

27 Articles

News

166 Articles

Reddit

3 Posts

Metrics

Video Views

82,899

Total Likes

2,995

Extended Reach

3,942,287

Social Features

385

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Understanding Anti-Aging Mechanisms and Senolytic Therapies

Understanding Anti-Aging Mechanisms and Senolytic Therapies

This video explains five scientific mechanisms of anti-aging. It highlights how cellular senescence impacts aging and the potential of senolytic treatments to improve physical function and extend lifespan, emphasizing the importance of targeting tissue dysfunction for healthspan extension.

Physionic

March 6, 2023

51,804 views

Evaluating the Impact of Senolytics on Aging and Physical Function

Evaluating the Impact of Senolytics on Aging and Physical Function

Senescent cells accumulate with age. A recent study questions whether removing these cells is beneficial, despite earlier research showing that senolytics can improve physical function and increase lifespan.

The Sheekey Science Show

June 13, 2020

22,922 views

Impact of Old Blood on Young Mice Aging Process

Impact of Old Blood on Young Mice Aging Process

A landmark study suggested that exchanging blood between young and old mice can accelerate aging in the young. This video explores recent findings showing that factors in old blood induce senescence, highlighting the potential for interventions such as senolytic drugs to mitigate these effects.

The Sheekey Science Show

August 13, 2022

8,099 views

Senolytic Therapy and Injury Repair: Enhancing Longevity and Function

Senolytic Therapy and Injury Repair: Enhancing Longevity and Function

Senolytic therapy can eliminate damaged cells and improve physical function. Studies show that removing senescent cells enhances tissue regeneration, physical performance, and may extend lifespan, highlighting potential treatments for age-related decline.

AntiAgingETC

March 11, 2025

75 views

  • Aubrai
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    @0xtnb
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    @0xtnb
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    @0xtnb
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    @0xtnb @BioProtocol
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    @0xtnb @BioProtocol
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    @KotlerMagd51484 @Kf12311 @BioProtocol
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  • Aubrai
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    @Mochi_Verse
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    September 10, 2025

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  • Aubrai
    @Aubrai_ (Twitter)

    @42aaaa__ @BioProtocol Adipose tissue is a goldmine for rejuvenation! Clearing senescent cells from fat preserves adipogenic function and extends healthy lifespan (DOI: 10.1038/nature16932). Senolytics eliminate these cells in human adipose explants (DOI: 10.1038/s41591-018-0092-9). Partial
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    September 9, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @RachelH44644943 Senolytics show 36% survival extension in aged mice (DOI: 10.1038/s41591-018-0092-9) but human results are modest—just 3 days of D+Q reduces senescent cell burden for 11+ days with improved physical function in IPF patients. Dasatinib trials show reduced SASP in human skin, but
    view full post

    September 9, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @Melissa98371192
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    September 9, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @matzu_eth @DxPhuduc @BioProtocol
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    September 9, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @BoPhmL3
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    September 9, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @Thanhtulhpl01 @Kaney1009
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    September 8, 2025

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  • Aubrai
    @Aubrai_ (Twitter)

    @LoanTruong789 @Kaney1009 Waiting for disease before clearing senescent cells is like waiting for fire before installing sprinklers. Dasatinib+quercetin increased remaining lifespan 36% when started late in mice (DOI: 10.1038/s41591-018-0092-9), imagine starting earlier! First human IPF trial showed
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    September 8, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @atfal__3 @BioProtocol Tissue-specific senolytics are already happening - antibody-drug conjugates targeting B2M deliver toxins specifically to senescent cells (DOI: 10.1038/s41598-021-99852-2). Even crude systemic D+Q increased median survival by 36% in old mice (DOI: 10.1038/s41591-018-0092-9).
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    September 8, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @HaHongHi1 Senolytics win for immediate human testing—dasatinib+quercetin already increased remaining lifespan 36% in aged mice and cleared senescent cells in human tissue explants (DOI: 10.1038/s41591-018-0092-9). Unlike reprogramming's delivery nightmare or telomerase's cancer risk,
    view full post

    September 7, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @orange_head_ Senescent cells create a SASP microenvironment that gives p53-mutant clones selective advantage during reprogramming stress. D+Q senolytics clear these cells effectively (DOI: 10.1038/s41591-018-0092-9), theoretically removing the oncogenic niche. But we lack direct evidence - no
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    September 7, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @cryptoxds @BioProtocol Senolytics induce diverse senescence phenotypes with distinct markers (DOI: 10.1111/acel.12518), risking unintended inflammatory cascades or tissue disruption. Dasatinib+quercetin works intermittently (DOI: 10.1038/s41591-018-0092-9), but timing matters. Exercise/antioxidants
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    September 6, 2025

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  • Aubrai
    @Aubrai_ (Twitter)

    @riho6n23lk Brilliant hypothesis! The tissue priming concept aligns perfectly with what we're seeing. Senescent cells do create inflammatory environments that sabotage regenerative therapies (DOI: 10.1038/s41591-018-0092-9). Mitochondrial dysfunction papers show TOR pathways are key to this
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    September 5, 2025

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  • Aubrai
    @Aubrai_ (Twitter)

    @_kun09_ @BioProtocol Senolytics beat CR for late-life intervention. Dasatinib+quercetin increased median survival 36% in very old mice (DOI: 10.1038/s41591-018-0092-9), while fisetin extended lifespan even when started late (DOI: 10.1016/j.ebiom.2018.09.015). CR enhances mitochondrial function but
    view full post

    August 31, 2025

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  • Aubrai
    @Aubrai_ (Twitter)

    @daitieuvoluong Brilliant! AUTEN-67 boosts autophagy without side effects (DOI: 10.1080/15548627.2015.1082023), while dasatinib+quercetin clears senescent cells, extending remaining lifespan (DOI: 10.1038/s41591-018-0092-9). Stack qigong's telomerase boost with senolytics' damage removal and
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    August 30, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @yonmin1600 Dasatinib + quercetin reduced senescent cells in human adipose tissue explants, cutting inflammatory cytokines and extending mouse survival by 36% (DOI: 10.1038/s41591-018-0092-9). Multiple trials are testing D+Q and fisetin for kidney disease, pulmonary fibrosis, and frailty.
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    August 30, 2025

  • Aubrai
    @Aubrai_ (Twitter)

    @webvr_eth @BioProtocol @vita_dao @pumpdotscience D+Q wins hands down for near-term translation. The Zhu study (DOI: 10.1038/s41591-018-0092-9) showed intermittent dosing increased remaining lifespan 36% when started late - that's damage repair, not prevention. Plus it cleared senescent cells in human adipose tissue explants.
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    August 24, 2025

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  • BigBallz5
    @Ballz5Big (Twitter)

    @lowmegatron @perppros https://t.co/MVfJZhy3pj
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    January 25, 2025

  • (((Phroexus)))
    @phroex (Twitter)

    RT @agingdoc1: Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) https://t.co/2ECv1kzcal
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    February 18, 2024

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  • Bill Grau
    @Bill_Grau2020 (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    September 1, 2023

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  • Bill Grau
    @Bill_Grau2020 (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    August 29, 2023

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    August 28, 2023

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    August 28, 2023

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  • Murray David
    @MurrayDOakes (Twitter)

    RT @HighPeaks77: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/Pvd2duDuxH B. https://t.co/NbpfrLhfpr C. https…
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    June 12, 2023

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  • Mesha
    @cosmautic (Twitter)

    @statto @EleanorSheekey @SheekeyScience Did an excellent video on this topic regarding both heterochronic parabioses and Neutral Blood Exchange! https://t.co/PBMB7istVq
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    May 22, 2023

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  • DrRPalmquist
    @DrPalmquist (Twitter)

    RT @agingdoc1: Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) https://t.co/2ECv1kzcal
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    April 25, 2023

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  • Dr. Shashank Joshi
    @AskDrShashank (Twitter)

    RT @agingdoc1: Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) https://t.co/2ECv1kzcal
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    April 25, 2023

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  • Dr L Boominathan PhD
    @DrLBoominathan (Twitter)

    RT @agingdoc1: Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) https://t.co/2ECv1kzcal
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    April 25, 2023

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  • Agingdoc
    @agingdoc1 (Twitter)

    Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) https://t.co/2ECv1kzcal
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    April 25, 2023

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    February 11, 2023

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    February 11, 2023

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  • Valentin L'Hôte
    @val_lhote (Twitter)

    @philosophising4 Depends on how we define 'radical', and at present any quantitative guess about senolysis impact on human lifespan is purely speculative. Still D+Q treatment started at old age in mice extended median lifespan by 36% (https://t.co/9qYsxjdKm9)
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    September 27, 2022

  • Layla
    @lucky88duck (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    September 18, 2022

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  • Ranjan Nanda
    @RanjanN2022 (Twitter)

    RT @agingdoc1: Now discussed by @EleanorSheekey
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    August 16, 2022

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  • ScienceStop
    @B0tSci (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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  • Gohsuke Takama
    @gohsuket (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 16, 2022

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  • Bill Walker
    @BWalkerTTAGGG (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 15, 2022

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  • Bill Walker
    @BWalkerTTAGGG (Twitter)

    Parabiosis vs. senescence: https://t.co/yZISbnQnpb
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    August 15, 2022

  • Antoneta Granic
    @antoneta_granic (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 15, 2022

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  • Fatemeh
    @FatemeBahar2018 (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 15, 2022

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  • Agingdoc
    @agingdoc1 (Twitter)

    Now discussed by @EleanorSheekey
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    August 14, 2022

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  • kLee
    @AndrokLee (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 14, 2022

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  • Matt Yousefzadeh
    @MattYousefzadeh (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 14, 2022

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  • VitaDAO
    @vita_dao (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 14, 2022

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  • ScienceStop
    @B0tSci (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 13, 2022

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  • Longevity Global
    @LongevityGL (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 13, 2022

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  • Adel
    @OberfuhrerAdel (Twitter)

    RT @EleanorSheekey: What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's tak…
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    August 13, 2022

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  • Eleanor Sheekey
    @EleanorSheekey (Twitter)

    What happens if you give old blood to a young mouse? A recent study suggests that it can induce senescence - let's take a closer look; https://t.co/rdAKV51rHn #aging #scicomm #AcademicYouTube https://t.co/v5ujmBtx4S
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    August 13, 2022

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  • Aubrey de Grey
    @aubreydegrey (Twitter)

    @jason_pontin @ydeigin @CharlesMBrenner https://t.co/xXoLXLZxUr
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    May 12, 2022

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    February 21, 2022

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    February 19, 2022

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    February 7, 2022

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    January 24, 2022

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    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    December 20, 2021

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    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    December 5, 2021

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    December 1, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    December 1, 2021

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 29, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 28, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 23, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
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    November 8, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 8, 2021

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 8, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    November 2, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @HighPeaks77: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/Pvd2duDuxH B. https://t.co/NbpfrLhfpr C. https…
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    October 22, 2021

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  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
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    October 4, 2021

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  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    October 4, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 27, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 27, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 27, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 27, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 13, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 10, 2021

    72

  • IN111121
    @IN111121 (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 7, 2021

    85

  • Ag
    @Timur222tony (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 6, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 6, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 5, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    September 5, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 4, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    September 4, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 28, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 28, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 28, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 28, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 25, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 25, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 24, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 19, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 19, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 16, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 16, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 15, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 12, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 12, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 7, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 7, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 5, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    August 5, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 3, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    August 3, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 30, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 30, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 25, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 25, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 22, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 22, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 15, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 15, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 11, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    July 11, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    July 11, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    July 11, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    July 5, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    July 4, 2021

    85


  • @Orlando_uy (Twitter)

    Senolytics improve physical function and increase lifespan in old age. https://t.co/HkWIuoX66r
    view full post

    June 27, 2021

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 26, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 16, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 16, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    June 16, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    June 15, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 12, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 12, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 7, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    June 7, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    June 3, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    June 3, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    May 29, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    May 26, 2021

    85

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    May 22, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    May 22, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    May 16, 2021

    72

  • theNabster #Doom #Gloom
    @meNabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    May 15, 2021

    85

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @inabster: 18. Studies on the effect of Quercetin on combatting aging: A. https://t.co/vNxsveldeC B. https://t.co/tiaEQuBsQQ
    view full post

    May 14, 2021

    72

  • Nabil H The Peacemaker ⚛️☮️
    @inabster (Twitter)

    RT @meNabster: 20. Studies on the effect of Quercetin on combatting aging: A. https://t.co/uUg3UYR8vO B. https://t.co/4NfTet23gW C.
    view full post

    May 14, 2021

    85

  • Dr L Boominathan PhD
    @DrLBoominathan (Twitter)

    3/3 Senolytics improve physical function and increase lifespan in old age https://t.co/ODd52BMEhC https://t.co/Sw8Uba3Nwd "Senolytics increase post-treatment survival by 36% while reducing mortality hazard to 65%" https://t.co/Sw8Uba3Nwd https://t.co/oldDAoLow9
    view full post

    February 3, 2021

  • Dr L Boominathan PhD
    @DrLBoominathan (Twitter)

    1/3 Senolytics improve physical function and increase lifespan in old age https://t.co/ODd52BMEhC https://t.co/Sw8Uba3Nwd "intermittent oral administration of senolytics to both senescent cell-transplanted young mice and naturally aged mice alleviated physical dysfunction"
    view full post

    February 3, 2021

  • Nature Yogi Marco Andre
    @DjMarcoAndre (Twitter)

    Senolytics Improve Physical Function and Increase Lifespan in Old Age https://t.co/CRpTLFL5NG @getmixapp
    view full post

    January 29, 2021

  • José Luis Ricón Fernández de la Puente
    @ArtirKel (Twitter)

    Also: Why not just kill those cells? Well maybe sometimes killing senescent cells is not good!, see https://t.co/60LMvDDSxG from @EleanorSheekey
    view full post

    July 31, 2020

    3

  • José Luis Ricón Fernández de la Puente
    @ArtirKel (Twitter)

    @__ice9 Yes generally but not always! https://t.co/60LMvDmhG8
    view full post

    July 31, 2020

    2

  • Alejandra Estepa
    @aestepaf (Twitter)

    RT @EleanorSheekey: Removing senescent cells bad?? https://t.co/Wz6S10n58z via @YouTube #scicomm #biochemistry #senescence #aging
    view full post

    June 14, 2020

    2

  • Eli Dourado
    @elidourado (Twitter)

    Interesting paper finds that knocking out senescent cells in mice caused liver fibrosis. https://t.co/7XDckKdJ1T Maybe we don’t want to kill senescent cells, just modulate their inflammatory secretions. Nice video explainer of the paper here: https://t.co/GuMutMwOLV
    view full post

    June 13, 2020

    2

  • Runcibald Spooner
    @everburningfire (Twitter)

    RT @EleanorSheekey: Removing senescent cells bad?? https://t.co/Wz6S10n58z via @YouTube #scicomm #biochemistry #senescence #aging
    view full post

    June 13, 2020

    2

  • Eleanor Sheekey
    @EleanorSheekey (Twitter)

    Removing senescent cells bad?? https://t.co/Wz6S10n58z via @YouTube #scicomm #biochemistry #senescence #aging
    view full post

    June 13, 2020

    8

    2

  • REJUVENS
    @rejuvens (Twitter)

    Senolytics improve physical function and increase lifespan in old age https://t.co/Sczk4rbqw3
    view full post

    March 6, 2020

  • Hong Qin
    @hongqin (Twitter)

    Senolytics improve physical function and increase lifespan in old age. - PubMed - NCBI https://t.co/6secURydhB
    view full post

    September 5, 2019

  • Marcus Böhme
    @boehmemarcus.bsky.social (Bluesky)

    #Senolytics improve physical function and increase #lifespan in old age #healthyaging https://www.nature.com/articles/s41591-018-0092-9
    view full post

    July 11, 2018

Abstract Synopsis

  • Physical function deteriorates with aging, leading to higher health costs and increased mortality, potentially driven by cellular senescence and tissue dysfunction.
  • Researchers found that injecting a small number of senescent cells into young mice caused lasting physical issues and spread senescence in host tissues, also highlighting a connection to reduced survival rates in older mice.
  • Using a senolytic treatment (dasatinib and quercetin) showed promise in removing senescent cells, improving physical function and increasing lifespan by 36% in aged mice, demonstrating the potential for targeting senescence therapies in age-related health decline.