Nutrients July 2018 PMID 30029482

l-Citrulline Supplementation: Impact on Cardiometabolic Health.

Timothy D Allerton, David N Proctor, Jacqueline M Stephens, Tammy R Dugas, Guillaume Spielmann, Brian A Irving

Mentions

65
Peak: 6 in May 2021
across 6 sources since Apr 2019

Extended reach

434,772
potential audience

Total likes

392

Video views

25,971

Mentions per month

Apr 2019 – Aug 2025

Where it's discussed

  • News29 articles
  • X / Twitter25 posts
  • Facebook5 posts
  • YouTube3 videos
  • Blogs2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Overall, this collection of discussions reflects a positive attitude toward the research findings, with many highlighting the potential health benefits of citrulline, such as blood vessel support and blood pressure regulation, using enthusiastic language like 'consistently increases' and 'reminder to get your watermelons.' The tone and choice of words convey curiosity, support, and a recognition of the supplement's promise, which influences the moderate impact score.

AgreementModerate agreement

Most discussions support the positive effects and potential benefits of citrulline supplementation, emphasizing improvements in blood vessel function and cardiovascular health.

InterestHigh interest

The topic appears highly relevant, attracting curiosity and personal health implications, especially among those interested in fitness and aging, as seen in mentions of watermelon, blood pressure, and well-being.

EngagementModerate engagement

Participants frequently reference specific effects like increased NO bioavailability, blood flow improvements, and practical applications, indicating meaningful engagement with the scientific content.

ImpactModerate impact

While some discussions suggest citrulline could have significant health benefits, most responses seem exploratory or supportive rather than documenting transformative impacts, reflecting moderate perceived influence.

Abstract in brief

  • Citrulline, found in watermelon, is more effective than L-arginine at increasing nitric oxide levels because it is better absorbed in the gut and used to recycle L-arginine, which supports blood vessel health and blood pressure regulation.
  • Supplementing with citrulline has shown potential benefits, such as lowering blood pressure in prehypertensive adults and protecting blood vessels from disease, especially in older populations.
  • Ongoing research explores how citrulline might improve overall cardiovascular and metabolic health through its effects on blood vessels and other pathways, highlighting its promise as a therapy for age-related health issues.]

Top posts

Most liked on X and Bluesky
Rene Sugar
@renesugar · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation consistently increases plasma and tissue levels of l-arginine and NO bioavailability" https://t.co/XuxD4fqU6z

Apr 17, 2022 · 25 likes · 6 shares · 3,973 followers View post →
Ronita De, PhD
@dronita_de · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 13, 2021 · 7 likes · 5 shares · 1,503 followers View post →
Rene Sugar
@renesugar · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/lwAKHeAIkR

Aug 16, 2024 · 2 likes · 3,973 followers View post →
Rene Sugar
@renesugar.bsky.social · Bluesky

L-Citrulline Supplementation: Impact on Cardiometabolic Health #citrulline #MECFS #LongCovid www.ncbi.nlm.nih.gov/pmc/articles... "However, in patients with vasospastic angina, 8 weeks of l-citrulline (800 mg/day) was sufficient to improve l-arginine/ADMA levels and FMD."

Feb 22, 2025 · 2 likes · 2 shares View post →
Rene Sugar
@renesugar · X

L-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHs1LSs

Sep 18, 2023 · 1 like · 1 share · 3,973 followers View post →
Ahmad Zahar
@Kuahmd · X

Citrulline extract Buah Tembikai. (Watermelon) Abstrak: Ketersediaan hayati nitrit oksida (NO) yang berkurang, molekul pemberi sinyal gas yang terlibat dalam pengaturan berbagai fungsi biologis vital, berkontribusi pada pengembangan... https://t.co/8vMC9zhj3X

Apr 4, 2019 · 1 like · 790 followers View post →

All mentions

Amarelowbr
@amarelowbr · X

RT @renesugar: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation…

Aug 23, 2025 · 6 shares · 845 followers View post →
Rene Sugar
@renesugar.bsky.social · Bluesky

L-Citrulline Supplementation: Impact on Cardiometabolic Health #citrulline #MECFS #LongCovid www.ncbi.nlm.nih.gov/pmc/articles... "However, in patients with vasospastic angina, 8 weeks of l-citrulline (800 mg/day) was sufficient to improve l-arginine/ADMA levels and FMD."

Feb 22, 2025 · 2 likes · 2 shares View post →
萌st Of Eden
@moe_the_2D · X

シトルリンの血管拡張作用の方が期待持てそう(有望としか書いてないみたいだけど)。アルギニンの経口摂取はほとんど効果無いぞとも書いてあるな。 https://t.co/JHmFGti1Xu https://t.co/7CLraDnguA

Feb 17, 2025 · 565 followers View post →
Rene Sugar
@renesugar · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/lwAKHeAIkR

Aug 16, 2024 · 2 likes · 3,973 followers View post →
Yurii
@Yurii08720681 · X

RT @renesugar: L-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHs1LSs

Sep 18, 2023 · 1 share · 36 followers View post →
Rene Sugar
@renesugar · X

L-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHs1LSs

Sep 18, 2023 · 1 like · 1 share · 3,973 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation…

Mar 16, 2023 · 6 shares · 3,973 followers View post →
Woody Nist
@Woodynist · X

L-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/m8NTIeJq8g

Dec 6, 2022 · 1,307 followers View post →
htw
@heniek_htw · X

RT @renesugar: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation…

Apr 25, 2022 · 6 shares · 11,284 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @renesugar: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation…

Apr 25, 2022 · 6 shares · 133,844 followers View post →
Rene Sugar
@renesugar · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/rbwiHsiOUs "oral l-citrulline supplementation consistently increases plasma and tissue levels of l-arginine and NO bioavailability" https://t.co/XuxD4fqU6z

Apr 17, 2022 · 25 likes · 6 shares · 3,973 followers View post →
Juan
@JuanOcampo44 · X

Daily reminder to get your L-citrulline in…Who doesn’t like watermelon? l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/RGaPGcYFao #mdpinutrients via @Nutrients_MDPI

Nov 13, 2021 · 1 like · 77 followers View post →
Slawomir
@Slawomi18369321 · X

RT @dronita_de: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 14, 2021 · 5 shares · 84 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @dronita_de: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 14, 2021 · 5 shares · 124,002 followers View post →
Dr. Rajeev K. Singla
@RajeevKSingla · X

RT @dronita_de: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 14, 2021 · 5 shares · 2,579 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @dronita_de: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 14, 2021 · 5 shares · 2,882 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @dronita_de: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 13, 2021 · 5 shares · 10,289 followers View post →
Ronita De, PhD
@dronita_de · X

l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/g4d7Z7Ynst #INPST #NPMND

May 13, 2021 · 7 likes · 5 shares · 1,503 followers View post →
Don’t take us for fuels #SaveGaza
@6Sally7 · X

RT @6Sally7: Interesting

Dec 1, 2020 · 1 share · 3,319 followers View post →
Don’t take us for fuels #SaveGaza
@6Sally7 · X

Interesting

Dec 1, 2020 · 1 share · 3,319 followers View post →
Don’t take us for fuels #SaveGaza
@6Sally7 · X

@Cov19longtail Supplemental Citrulline (commonly used by body builders ) may help you: https://t.co/bs4ew8PQgp

Oct 9, 2020 · 3,319 followers View post →
abdul ghani qiq
@cintaforex · X

https://t.co/VbaoPwOyZY

Mar 30, 2020 · 74,700 followers View post →
Dragan Dexter #blm (parody account)
@BeckySamson7 · X

"l-Citrulline Supplementation: Impact on Cardiometabolic Health" https://t.co/3qh9Nms2NE "l-Citrulline Supplementation: Impact on Cardiometabolic Health" https://t.co/3qh9Nms2NE

Dec 7, 2019 · 362 followers View post →
#HelpYouGetGAINS
@helpYOUgetGAINS · X

Study: l-Citrulline Supplementation: Impact on Cardiometabolic Health https://t.co/dAXkz7OVzX

Sep 28, 2019 · 16,881 followers View post →
Ahmad Zahar
@Kuahmd · X

Citrulline extract Buah Tembikai. (Watermelon) Abstrak: Ketersediaan hayati nitrit oksida (NO) yang berkurang, molekul pemberi sinyal gas yang terlibat dalam pengaturan berbagai fungsi biologis vital, berkontribusi pada pengembangan... https://t.co/8vMC9zhj3X

Apr 4, 2019 · 1 like · 790 followers View post →
Ahmad Zahar
@Kuahmd · X

Citrulline. Abstrak: Ketersediaan hayati nitrit oksida (NO) yang berkurang, molekul pemberi sinyal gas yang terlibat dalam pengaturan berbagai fungsi biologis vital, berkontribusi pada pengembangan dan perkembangan berbagai... https://t.co/8vMC9zhj3X

Apr 4, 2019 · 790 followers View post →