Front Immunol September 2019 PMID 30105028

Innate Immunity of Neonates and Infants.

Jack C Yu, Hesam Khodadadi, Aneeq Malik, Brea Davidson, Évila da Silva Lopes Salles, Jatinder Bhatia, Vanessa L Hale, Babak Baban

Mentions

15
Peak: 2 in Apr 2022
across 4 sources since Feb 2020

Extended reach

118,146
potential audience

Total likes

98

Video views

2,015

Mentions per month

Feb 2020 – Sep 2025

Where it's discussed

  • X / Twitter9 posts
  • YouTube2 videos
  • Facebook2 posts
  • News2 articles

AI synopsis

What people are saying

The discussion reflects a balanced recognition of innate immunity's role in neonates, with comments like 'Science would disagree. It's what humans rely on...' indicating a nuanced debate about immune development. The tone ranges from supportive to skeptical, affecting the overall moderate scores, and references to complement levels and immune mechanisms suggest an engaging but not deeply investigative dialogue.

AgreementModerate agreement

Most discussions acknowledge the importance of innate immunity in neonates, with some challenging the idea that neonates lack innate immune responses, supporting the publication's perspective.

InterestModerate interest

The posts demonstrate moderate curiosity, with commenters referencing specific immune mechanisms and developmental details, showing some engagement but not intense enthusiasm.

EngagementNeutral engagement

While some participants question or elaborate on immune functions, the overall dialogue remains rather superficial without deep analysis or extensive evidence sharing.

ImpactModerate impact

The conversations highlight the significance of neonatal immune development and suggest the topic influences understanding of infant health, indicating moderate impact in scientific or health-related contexts.

Abstract in brief

  • The birth process subjects a neonate to a drastically different environment, requiring the development and adaptation of its immune system to effectively interact with various organisms.
  • The neonatal immune system is particularly tolerant and adaptable due to experiences during gestation and significant exposure to new antigens, functioning under a "quiescent mode" that supports early life.
  • Innate lymphoid cells (ILCs) are especially active during infancy compared to adulthood, highlighting their potential role in influencing health conditions throughout a person’s life, and the review draws parallels between immune functions and national defense strategies.

Top posts

Most liked on X and Bluesky
La Jefita
@soylajefita · X

Apr 26, 2022 · 41 likes · 1 share · 78,738 followers View post →
Oliver Slay
@oliverslay · X

@AkleSebastian @Salahud33nMirza @StevePittelli @doctorveera Do levels of C4 in dried neonatal blood spots correlate with post-synaptic density concentrations of C4 in the brain throughout the first 14 years of life? Complement system is still in development at birth (reviewed in doi:10.3389/fimmu.2018.01759)

Nov 16, 2022 · 2 likes · 238 followers View post →
Michael Lin, MD PhD
@michaelzlin · X

@theBianLiu It seems infants are similarly protected as other children <10yo (https://t.co/t8MOKvSFeS). Certain innate immune mechanisms are weaker infants, but some are stronger (https://t.co/68pVa7EW5C). Apparently on balance it works okay.

Dec 1, 2020 · 1 like · 28,101 followers View post →
Hypoautonomic
@hypoautonomic · X

@DrMBrandt @19joho @AlastairMcA30 "Infants do not have innate immunity." embarrassing https://t.co/e55mrXrE8Y https://t.co/hNo3cs2dSF

Feb 2, 2023 · 1 like · 771 followers View post →
TruthSeeker
@VeritasEver · X

RT @mcfunny: @_aconscioussoul @KristenJayne1 @KatLaRue7 @MomUrich @runhack @jkellyca @RogueTrader84 @Just4TheCause @provaxtexan @MsTrixter…

Feb 23, 2020 · 1 share · 4,608 followers View post →
kaiser
@Kaiserofl06 · X

RT @soylajefita:

Apr 26, 2022 · 1 share · 2,699 followers View post →

All mentions

知今実布人(プローブ)
@probeFrom2019 · X

新生児と乳児の自然免疫力 https://t.co/G9LFWMx29u

May 9, 2025 · 76 followers View post →
mumzles
@mumzles1 · X

@RiverIsMee @SieviePacem @AngryCitizenxx Science would disagree. It’s what humans rely on until adaptive immunity develops. If it wasn’t strong in neonates, our species would not be here. https://t.co/3ZXonRyHnO

Jan 31, 2025 · 201 followers View post →
Eastaquarian
@eastaquarian · X

@Sal_Robins @Ind3pendent7 @RobynGrauer https://t.co/TgozoaDs8b

Jul 6, 2023 · 694 followers View post →
Hypoautonomic
@hypoautonomic · X

@DrMBrandt @19joho @AlastairMcA30 "Infants do not have innate immunity." embarrassing https://t.co/e55mrXrE8Y https://t.co/hNo3cs2dSF

Feb 2, 2023 · 1 like · 771 followers View post →
Oliver Slay
@oliverslay · X

@AkleSebastian @Salahud33nMirza @StevePittelli @doctorveera Do levels of C4 in dried neonatal blood spots correlate with post-synaptic density concentrations of C4 in the brain throughout the first 14 years of life? Complement system is still in development at birth (reviewed in doi:10.3389/fimmu.2018.01759)

Nov 16, 2022 · 2 likes · 238 followers View post →
kaiser
@Kaiserofl06 · X

RT @soylajefita:

Apr 26, 2022 · 1 share · 2,699 followers View post →
La Jefita
@soylajefita · X

Apr 26, 2022 · 41 likes · 1 share · 78,738 followers View post →
Michael Lin, MD PhD
@michaelzlin · X

@theBianLiu It seems infants are similarly protected as other children <10yo (https://t.co/t8MOKvSFeS). Certain innate immune mechanisms are weaker infants, but some are stronger (https://t.co/68pVa7EW5C). Apparently on balance it works okay.

Dec 1, 2020 · 1 like · 28,101 followers View post →
TruthSeeker
@VeritasEver · X

RT @mcfunny: @_aconscioussoul @KristenJayne1 @KatLaRue7 @MomUrich @runhack @jkellyca @RogueTrader84 @Just4TheCause @provaxtexan @MsTrixter…

Feb 23, 2020 · 1 share · 4,608 followers View post →