Discussions demonstrate strong interest, with posts highlighting molecular geometry and its role in drug development, exemplified by phrases like 'fun geometric molecules' and 'explore medicinal chemistry,' indicating enthusiasm. Engagement is evidenced by sharing resource links and debating future applications, showing users are invested in understanding and discussing the potential impact of cubanes in pharmaceuticals.
AgreementModerate agreement
Most discussions acknowledge the significance of cubanes in medicinal chemistry, with some showing enthusiasm for their potential applications.
InterestHigh interest
The topic sparks high curiosity, as evidenced by exchanges emphasizing the intriguing geometry and chemical properties of cubanes.
EngagementModerate engagement
Posts reflect active engagement through sharing links, commenting on the structural features, and discussing their synthesis and therapeutic potential.
ImpactModerate impact
The collective tone suggests that this research is viewed as an important development, though not universally regarded as a revolutionary breakthrough yet.
Abstract in brief
Cubane is a highly strained but stable hydrocarbon molecule that has gained interest in medicinal chemistry because of its unique structure and low toxicity.
Its structure allows chemists to modify each carbon atom, creating complex molecules that can be used to study and target biological active sites in pharmaceuticals.
The text discusses how chemists synthesize various functionalized cubanes, their applications in drug development, and future challenges and opportunities in this research area.]
من الوارد جداً أن نشاهد مستقبلاً مركبات معتمدة للاستعمال الدوائي وتحتوي على هذا المكعب ولكن العائق حالياً هو صعوبة إجراء تفاعلات لهذا النوع من المركبات
ولمن أراد معرفة المزيد عن هذه المركبات فيمكنه الرجوع لهذين البحثين:
https://t.co/dmgL4M7CQK
https://t.co/DdQhyzA1lE
May 20, 2020 · 9 likes · 4,936 followersView post →
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Chemspace
@Chem_space · X
Some fun geometric molecules this weekend! Explore the medicinal chemistry and our selected set of cubanes by this link: https://t.co/6VzhSwt22M
.
#chemspace #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals https://t.co/6HUlVFbHpu
Cubanes are a unique class of molecules explored for their potential in medicinal chemistry. In this video, we discuss their use as a substitute for Benzene rings in new drug candidates and highlight various Cubane…
Cubane is a highly strained but stable hydrocarbon molecule gaining interest in medicinal chemistry because of its unique structure and low toxicity. This video discusses its synthesis, applications in drug development…
Some fun geometric molecules this weekend! Explore the medicinal chemistry and our selected set of cubanes by this link: https://t.co/6VzhSwt22M
.
#chemspace #organicchemistry #drugsynthesis #science #openscience #research #drugdiscovery #chemicals https://t.co/6HUlVFbHpu
من الوارد جداً أن نشاهد مستقبلاً مركبات معتمدة للاستعمال الدوائي وتحتوي على هذا المكعب ولكن العائق حالياً هو صعوبة إجراء تفاعلات لهذا النوع من المركبات
ولمن أراد معرفة المزيد عن هذه المركبات فيمكنه الرجوع لهذين البحثين:
https://t.co/dmgL4M7CQK
https://t.co/DdQhyzA1lE
May 20, 2020 · 9 likes · 4,936 followersView post →
SU
Scientific Update
@SciUp · X
Cubanes in Medicinal Chemistry https://t.co/7gcMcwYGW1
Beilstein J Org Chem-20-859 | PDF | Ester | Chemical Reactions
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Funding J. Med. Chem. 2019, 62, 1078–1095. We wish to acknowledge the Georg-August-Universität doi:10.1021/acs.jmedchem.8b00888 18. Dragovich, P. S.; Prins ...
Cubane to COT: Synthesis Insights | PDF | Ketone | Organic Chemistry
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Kassiou, J. Med. Chem. DOI: https://doi.org/10.1021/acs.jmed- Littler, D. A. Winkler, P. V. Bernhardt, C. Pasay, J. J. De Voss, J. McCarthy, chem.8b00888; c ...
From thiol-subtilisin to omniligase: Design and structure of a broadly ...
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Link to the paper on the ACS Biochemistry website: https://pubs.acs.org/doi/pdf/10.1021/acs.biochem. 8b00888 ... J.Med.Chem ... About a month ago a ...
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