How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i explore in this weeks video --> https://t.co/1IDIKkBqlH #circadianrhythm #circadianclocks #scicomm #AcademicYouTube @LongevityTech https://t.co/pLuuL1V06u
Universal method for robust detection of circadian state from gene expression.
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Jun 2020 – May 2023Where it's discussed
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News74 articles
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X / Twitter12 posts
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Facebook12 posts
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Blogs12 articles
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Reddit3 posts
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YouTube2 videos
AI synopsis
What people are saying
The discussions reflect a positive reception, with posts emphasizing the method's robust and universal nature, like the mention of TimeSignature's performance across datasets. The tone combines curiosity about biological clocks, with some posts exploring practical implications for aging and medicine, demonstrating both interest and recognition of potential significance.
Most discussions acknowledge the significance of the new method, with comments highlighting TimeSignature's advantages over existing techniques.
Posts demonstrate strong curiosity about circadian rhythms and their relation to aging, showing active engagement with the topic.
Comments include references to specific studies and viewers engaging with the biological implications, indicating moderate thoughtful interaction.
Posts imply the research could influence future circadian studies and clinical applications, but real-world impact remains to be fully seen.
Abstract in brief
- The study introduces TimeSignature, a new algorithm that accurately determines a person's circadian (biological) time based on gene expression data, even across different measurement platforms and datasets.
- TimeSignature outperforms existing methods by consistently estimating circadian time within 2 hours for most samples, and it can be applied to new data without the need for re-training or data normalization.
- This approach overcomes a major challenge in biomarker development by providing a universal, reliable tool for assessing circadian rhythms, which can improve diagnosis and treatment timing for sleep and health disorders.]
Top posts
Most liked on X and Bluesky"High-accuracy determination of internal circadian time from a single blood sample" Nicole Wittenbrink et al. https://t.co/p4WCYIbTGv "Universal method for robust detection of circadian state from gene expression" Rosemary Braun et al. https://t.co/RORXL7XJXC -->
@ProfKantermann @SleepAndSports I agree DLMO is tricky, but 1-to-2 sample blood tests – there is also TimeSignature by Allada and colleauges https://t.co/mkCo8vbbMs – are not (as far as I know) as well characterized across different conditions/populations (?) (first validation in their JCI study was in n=28)
|・ω・`)フムフム "Circadian rhythms and aging." on YouTube - https://t.co/wwGlb4BaNd
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
All mentions
Understanding Chronotypes and Circadian Rhythms in Humans
Discover your circadian rhythm and why some people function better at different times of the day. The video explains chronotypes, the scientific basis of biological clocks, and introduces TimeSignature, an innovative…
The Role of Circadian Rhythms in Aging and Metabolic Health
The circadian rhythm is a natural cycle that regulates metabolic, physiological, behavioral, and cellular activities over 24 hours. Disruptions to this rhythm are linked to diseases and aging. Understanding this…
@ProfKantermann @SleepAndSports I agree DLMO is tricky, but 1-to-2 sample blood tests – there is also TimeSignature by Allada and colleauges https://t.co/mkCo8vbbMs – are not (as far as I know) as well characterized across different conditions/populations (?) (first validation in their JCI study was in n=28)
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
Circadian rhythms and aging. https://t.co/uFk0grVkdX via @YouTube
|・ω・`)フムフム "Circadian rhythms and aging." on YouTube - https://t.co/wwGlb4BaNd
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
RT @EleanorSheekey: How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i e…
How are circadian rhythms connected with #aging and can this knowledge be exploited for circadian medicine? Well, i explore in this weeks video --> https://t.co/1IDIKkBqlH #circadianrhythm #circadianclocks #scicomm #AcademicYouTube @LongevityTech https://t.co/pLuuL1V06u
"High-accuracy determination of internal circadian time from a single blood sample" Nicole Wittenbrink et al. https://t.co/p4WCYIbTGv "Universal method for robust detection of circadian state from gene expression" Rosemary Braun et al. https://t.co/RORXL7XJXC -->
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