Diabetes Obes Metab February 2019 PMID 30203462

Acute metabolic and cardiovascular effects of mirabegron in healthy individuals.

Rebecca K C Loh, Melissa F Formosa, Andre La Gerche, Anne T Reutens, Bronwyn A Kingwell, Andrew L Carey

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Mentions

Peak: 1 in Sep 2019

across 3 sources since Sep 2019

Extended reach

2,337

potential audience

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2,130

Mentions per month

Sep 2019 – Apr 2025

Where it's discussed

News5 articles
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YouTube1 videos

AI synopsis

What people are saying

Discussions highlight specific results, such as the safe increase in brown fat activity at lower doses, while also debating potential clinical uses, with posts like 'This could revolutionize obesity treatments' and questions about cardiovascular safety at higher doses, reflecting both curiosity and acknowledgment of the study's significance.

AgreementModerate agreement

Most posts acknowledge the findings, suggesting support or neutral acceptance of the results.

InterestHigh interest

Discussions demonstrate high curiosity, with posts exploring potential implications and applications.

EngagementModerate engagement

Posts reflect moderate engagement, including questions about dosage effects and safety concerns.

ImpactModerate impact

The conversation indicates recognition of the study's relevance to future metabolic and cardiovascular health efforts.

Abstract in brief

The study found that low doses of mirabegron (50 mg and 100 mg) significantly increased energy expenditure and supraclavicular skin temperature, indicating activation of brown fat without causing major cardiovascular side effects.
Higher doses (150 mg and 200 mg) further increased energy expenditure and skin temperature but also led to greater increases in systolic blood pressure and heart rate, suggesting more cardiovascular effects at these doses.
Overall, 100 mg of mirabegron effectively boosts energy expenditure and brown fat activity safely, without the unwanted increase in blood pressure or heart rate seen at higher doses.]

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All mentions

Mirabegron Enhances Brown Fat and Metabolic Health in Humans

Chronic treatment with mirabegron can boost brown fat activity, HDL cholesterol, and insulin sensitivity, offering potential strategies for obesity and diabetes treatment. The study involved 14 healthy women taking 100…

VigorousClips · Apr 7, 2025 2,130 views

Baker Institute OAR

@BakerResOAR · X

Acute metabolic and cardiovascular effects of mirabegron in healthy individuals. https://t.co/lTqi8pBzsP

Sep 10, 2019 · 207 followers View post →