Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does it work? Fisetin binds and removes iron https://t.co/M460sol44b
Fisetin is a senotherapeutic that extends health and lifespan.
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Oct 2018 – Nov 2025Where it's discussed
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What people are saying
The discussions widely agree on fisetin's efficacy, with posts citing studies showing its ability to reduce senescence, extend lifespan, and improve tissue health in animals. The tone ranges from scientific detail to speculation on human benefits, indicating strong interest and perceived significance of the research findings.
Most discussions strongly support the findings, emphasizing fisetin's potent senolytic effects and its potential to extend health and lifespan.
Participants show high curiosity, referencing multiple studies, mechanisms, food sources, and potential clinical applications of fisetin.
Many users delve into technical details, such as mechanisms of action, cell-type specificity, and lifespan data, indicating deep engagement.
The collective tone suggests these discussions could influence health practices and research directions, highlighting fisetin's transformative potential.
Abstract in brief
- Senescence is a protective mechanism in cells that prevents the replication of damaged DNA, contributing to aging and diseases; the study explored flavonoids, particularly fisetin, as potential senolytic agents to combat age-related conditions.
- Fisetin was identified as the most effective flavonoid, significantly reducing senescence markers in progeroid and aging mice, and showing cell-type specificity in human adipose tissue, indicating its targeted impact on aging cells.
- Administration of fisetin in older mice improved tissue health, decreased aging-related diseases, and extended lifespan, suggesting its potential for human clinical applications in promoting health during aging.
Top posts
Most liked on X and Bluesky- 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と寿命を延ばす老化治療薬であるhttps://t.co/oN8Z2k0l8k
Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
#BioPSI #ingredient #highlight : #FISETIN - Research shows Fisetin is a senotherapeutic that extends #health and #lifespan #nootropics #longevity #brain #antiaging #senolytic https://t.co/C37rbFgi8h
2️⃣ FISETINA:
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/h0UrmczrBh
All mentions
Senolytic Drugs Reduce Aging-related Cell Aging and Improve Metabolic Health
Senolytic drugs dasatinib and quercetin reduce cell senescence and inflammation in fat tissue of older mice, leading to improved metabolic functions such as blood glucose regulation and lowered blood fats.
Fisetin's Senolytic Potential and Impact on Aging and Health
This video explores fisetin's ability to activate SIR1, its senolytic potential, safety profile, bioavailability, and clinical trials, comparing it to quercetin. Fisetin shows promise as a senotherapeutic to extend…
Fisetin Extends Lifespan and Improves Health in Aged Mice
Researchers show that Fisetin, a natural compound found in fruits and vegetables, reduces senescent cells, improves tissue health, and extends lifespan in aged mice, highlighting its potential as a senotherapeutic for…
Optimizing Sleep Posture for Brain Waste Clearance and Longevity
This video discusses how body posture during sleep impacts the brain's glymphatic system, which clears waste like amyloid. Lateral sleep positions promote faster waste removal, potentially influencing aging and…
Fisetin as a Senolytic Agent to Extend Healthspan and Lifespan
What if aging isn't inevitable but treatable? This exploration highlights fisetin, a natural flavonoid, as a promising senolytic agent that reduces cellular senescence, improves tissue health, and potentially extends…
などを食べる https://t.co/nNZwiwY8Tr 2006年の実験 フィセチンでマウスの記憶力がアップした https://t.co/XJ4tZVZKnD #自分用メモ
RT @Lordnewsbrasil: 2️⃣ FISETINA:
2️⃣ FISETINA:
@hangduong9390
@_kun09_ @BioProtocol Senolytics beat CR for late-life intervention. Dasatinib+quercetin increased median survival 36% in very old mice (DOI: 10.1038/s41591-018-0092-9), while fisetin extended lifespan even when started late (DOI: 10.1016/j.ebiom.2018.09.015). CR enhances mitochondrial function but
@troyberlin Many already take Fisetin because they saw it increases longevity in animals. Most would think that's a good thing. https://t.co/k2404gHtxi
#BioPSI #ingredient #highlight : #FISETIN - Research shows Fisetin is a senotherapeutic that extends #health and #lifespan #nootropics #longevity #brain #antiaging #senolytic https://t.co/C37rbFgi8h
#BioPSI #ingredient #highlight : #FISETIN - Research shows Fisetin is a senotherapeutic that extends #health and #lifespan #nootropics #longevity #brain #antiaging https://t.co/C37rbFgi8h
#BioPSI #ingredient #highlight : #FISETIN - Research shows Fisetin is a senotherapeutic that extends #health and #lifespan #nootropics #longevity #brain https://t.co/C37rbFgi8h
#BioPSI #ingredient #highlight : #FISETIN - Research shows Fisetin is a senotherapeutic that extends #health and #lifespan https://t.co/C37rbFgi8h
@vipintukur https://t.co/XOPMZRd4In The natural product fisetin has senotherapeutic activity in mice and in human tissues. Late life intervention was sufficient to yield a potent health benefit. These characteristics suggest the feasibility to translation to human clinical studies. #fisetin https://t.co/ICHiOE0v2L
@marc_dema @jpsenescence @KarlPfleger So a "compound with some senolytic effect in some contexts" is not a senolytic? Some (below) report it's a "potent senolytic", "consistent with a hit-and-run senolytic mechanism". If the "extended median and maximum lifespan" isn't reproducible, what is? https://t.co/mfMGXOWhQo
Fisetin is one the most potent senolytics one can take. It is available as a supplement , but also contained in food. Top food for fisetin is strawberries at 160microgram/gram of strawberries. But the supplement form contains 100mg-500mg per capsule. https://t.co/MrnSg3fV1c https://t.co/MSR7aecVVW
RT @nealasher: https://t.co/ql39IgSWzy
https://t.co/ql39IgSWzy
@HeidiHmoretti @HiljaGebest Fisetin is the most powerful senolytic ever discovered in nature "Administration of fisetin to wild-type mice late in life restored tissue homeostasis, reduced age-related pathology, and extended median and maximum lifespan." https://t.co/XOPMZRcwSP https://t.co/dlXbhnp9vp
2. Fisetin is a senotherapeutic that extends health and lifespan “Findings: Of the 10 flavonoids tested, fisetin was the most potent senolytic.” https://t.co/5CLpuyZEtD.
RT @amarelowbr: Fisetin is a senotherapeutic that extends health and lifespan Administration of fisetin to wild-type mice late in life res…
Fisetin is a senotherapeutic that extends health and lifespan Administration of fisetin to wild-type mice late in life restored tissue homeostasis, reduced age-related pathology, and extended median and maximum lifespan. https://t.co/XOPMZRcwSP #fisetin #fisetina #lifespan
RT @LeeMarie222: The Anti-Aging Effect of Removing Zombie Cells [7 Studies] https://t.co/Iv6m6OsK9s via @YouTube
The Anti-Aging Effect of Removing Zombie Cells [7 Studies] https://t.co/Iv6m6OsK9s via @YouTube
https://t.co/b1M3pW9gJt
Source
Day 5 of fisetin mega-dosing. Nocebo effect making me feel knackered? Or is the stuff actually killing off senescent cells? I believe it to be the latter because on occasionI’ve wondered at my lack of energy only to then remember I’m taking the stuff. https://t.co/WQMRllw3fB
En comparación con otros flavonoides, la fisetina ha mostrado la actividad senolítica más potente
細胞が老化する際、SASPという有害な物質が産生され、組織の修復や免疫系が損傷されます。こちらによると、SASPを低下させるためにはフィセチンが有効だそうです。フィセチンを含むリンゴや玉葱の消費を増やしていきたいものですね。 https://t.co/Qvy4htHmyn
@RealCheckMarker https://t.co/oPypl854o7.
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/h0UrmczrBh
Fisetin is an interesting flavonoid. One study showed that compared to 10 other flavonoids, it was most effective at reducing markers to extend health & lifespan. The investigators suggested - it may improve healthy aging, even in older populations. https://t.co/D6oUWVETVP
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/oIGQSfbsPN
#Fisetin is a senotherapeutic that extends health and lifespan Fisetin reduced senescence in a subset of cells in murine and human adipose tissue, demonstrating cell-type specificity. #LawsOfNature #PlantPower https://t.co/lfIWIjAXyA
@EvanZhao6 @mkaeberlein That's incorrect: " #Fisetin reduced senescence in a subset of cells in murine and human adipose tissue, demonstrating cell-type specificity." https://t.co/qAc9CGNDxm
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/sVoyiR0R1X
@runsalot48 @mkaeberlein They all have very strong data. https://t.co/D7LtaWV3XL https://t.co/MP8xP5cRFs https://t.co/FnUudT72qX
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
RT @Mangan150: Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does…
Fisetin is a senotherapeutic that extends health and lifespan You may have seen that from a couple years ago But how does it work? Fisetin binds and removes iron https://t.co/M460sol44b
RT @deNutrients: @wendylee21742 @DCGreenZone1 @Parsifaler Fisetin is one that reduces senescence. Quercetin & dispantinin (sp?) Flavanoids…
RT @deNutrients: @wendylee21742 @DCGreenZone1 @Parsifaler Fisetin is one that reduces senescence. Quercetin & dispantinin (sp?) Flavanoids…
RT @deNutrients: @wendylee21742 @DCGreenZone1 @Parsifaler Fisetin is one that reduces senescence. Quercetin & dispantinin (sp?) Flavanoids…
@wendylee21742 @DCGreenZone1 @Parsifaler Fisetin is one that reduces senescence. Quercetin & dispantinin (sp?) Flavanoids https://t.co/m7BREwhNxJ.
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
RT @fdzaraf: - 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と…
- 老化とは, ストレスを受けた細胞内で活性化され, 傷ついたDNAの複製を妨げるための腫瘍抑制装置である。 - 老化細胞は, 骨粗しょう症や心血管疾患など様々な加齢関連疾患を引き起こす原因となる役割を果たす。 2018/9/29 フィセチンは健康と寿命を延ばす老化治療薬であるhttps://t.co/oN8Z2k0l8k
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/5i1x7oFEjA To gain mechanistic insights into ageing and longevity: https://t.co/ev3fKAQQ7D https://t.co/Sw8Uba3Nwd https://t.co/wh9gN20iKu
RT @CharlesDorman: Fisetin is a senotherapeutic that extends health and lifespan https://t.co/XT5umBy7OM
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/GpyjAb3gAT
@ResonantPyre @PYeerk Yes, we're on the cusp of very real healthspan gains I believe. Check out fisetin. I mean I have seen enough hypes fizzle out to be jaded, but this isn't some p<0.049 quackery that's only noticeable after data processing. And there's more in the pipeline. https://t.co/qbDPCq24TO https://t.co/4NB9lch8Gx
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/XT5umBy7OM
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/XT5umBy7OM
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/l5NPzOZ7LE
Fisetin is a senotherapeutic that extends health and lifespan: Strawberry is rich in fisetin. https://t.co/phNNx7Mnpq
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/JiV2ZypbB6
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/7YHr7VoW3L @getmixapp
@Blagosklonny Fisetin, however, increases median lifespan. https://t.co/b6IADinSKz
Alternative flavonoids are now being tested for their potential senolytic effects, such as Fisetin, which is able to eliminate senescent cells and, crucially, restore tissue function in aged mice. https://t.co/z7L85Of90L
@markoftheD You may find this on Fisetin interesting if you're looking for a potentially powerful senolytic: https://t.co/oQAsdeK3bX https://t.co/5AJc3tZ0g6
Fisetin is a senotherapeutic that extends health and lifespan - ScienceDirect https://t.co/tOCdP0GNE9
RT @DrLBoominathan: What we said on 19/September/2017: https://t.co/uTdsZsabXO What they said on 29/September/2019: Fisetin is a senother…
Check out "Scientist explains Dave Asprey's book Super Human" at: https://t.co/SFnL5NXsxm
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In my latest video I discuss "Super Human" - by @bulletproofexec Dave Asprey (overview & thoughts) https://t.co/iTnFUENui2 via @YouTube #SuperHuman #book #reading #scicomm
RT @Blagosklonny: @RoryPaltridge @evanmr Thank you for useful hint. I was familiar with one paper because i am an editor . But now i see in…
@RoryPaltridge @evanmr Thank you for useful hint. I was familiar with one paper because i am an editor . But now i see interesting continuation of the story. "Fisetin is a senotherapeutic that extends health and lifespan" Will read more about late developments with #Fisetin https://t.co/iDXYbEGb4E
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/MB3XHbAb6A
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
Fisetin is a [senotherapeutic] that extends health and lifespan - EBioMedicine https://t.co/DWUng0jVmX
What we said on 19/September/2017: https://t.co/uTdsZsabXO What they said on 29/September/2019: Fisetin is a senotherapeutic that extends health and lifespan https://t.co/i2gMa2yOlz
Fisetin increases life span via up-regulation of its target gene BubR1, 26/January/2017, 11.30 pm – Genome Discovery https://t.co/LtUN43JmJk; Proof of principle: Fisetin is a senotherapeutic that extends health and lifespan https://t.co/i2gMa2yOlz
Fisetin is a senotherapeutic that extends health and lifespan - ScienceDirect https://t.co/4Yi6Gv3cqb
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/JrWrQtOgiA
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/XOLNzbPe6Y
@zazen71 @OskaArcher And to close out, fisetin is very structurally similar to apigenin, and it proves to be a very selective senolytic⁴ (kills senescent cells without killing healthy cells). Apigenin doesn’t do that. 4. https://t.co/HBCWuGq9Sf
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/29RsD4TWj6
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/aDI8efEcGS
Fisetin is a senotherapeutic that extends health and lifespan https://t.co/jok046y7b7
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
RT @_atanas_: Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
Fisetin is a senotherapeutic that extends health and lifespan. - PubMed - NCBI https://t.co/CpbQHU8ThA
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