Cell October 2018 PMID 30318151

In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.

Katie McDole, Léo Guignard, Fernando Amat, Andrew Berger, Grégoire Malandain, Loïc A Royer, Srinivas C Turaga, Kristin Branson, Philipp J Keller

Mentions

84
Peak: 13 in Nov 2019
across 6 sources since Oct 2018

Extended reach

1,143,463
potential audience

Total likes

11,309

Video views

839,319

Mentions per month

Oct 2018 – Feb 2023

Where it's discussed

  • X / Twitter44 posts
  • News18 articles
  • Facebook10 posts
  • Blogs8 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The overall tone suggests strong recognition of the publication's importance, with some posts calling it 'the new Bible' and emphasizing its groundbreaking approach. Words like 'adapts itself' and mentions of advanced imaging techniques convey excitement about technological innovations. Additionally, references to related methods, such as machine learning applications, indicate active engagement with the content's broader implications in developmental biology.

AgreementModerate agreement

Many references acknowledge the significance of the publication, with phrases like 'Here the new Bible' and the inclusion of the article's citation, indicating strong support or acknowledgment of its importance.

InterestHigh interest

Several discussions highlight curiosity about the methodology and implications, such as mentioning new tools like light-sheet microscopy and neural networks, showing active interest in the technological advancements.

EngagementModerate engagement

Some posts go further by discussing related techniques like machine learning for cell analysis, sharing detailed observations, and referencing other researchers' work, suggesting a moderate level of deep engagement.

ImpactHigh impact

The enthusiasm expressed through hashtags like '#reproducibility', and references to the article as a 'new Bible' or indicating 'trend' scores, reflect a perception of high impact within the scientific or research community.

Abstract in brief

  • This study introduces a special lightsheet microscope that can adapt to changing mouse embryo sizes and shapes, allowing scientists to watch cell behavior during early development stages like gastrulation and organ formation.
  • The researchers also created advanced computer tools to track cell movements, divisions, and tissue changes over time within the embryo, building a detailed dynamic map of development.
  • By analyzing multiple embryos together, they made a comprehensive "dynamic atlas" of postimplantation mouse development, which serves as a valuable resource for understanding how tissues and organs form.

Top posts

Most liked on X and Bluesky
DNA&RNA Universe
@DNA_RNA_Uni · X

In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZMZfZroER8 source vid: https://t.co/1wE2YXI1mW #science #biology #microscopy #fluorescence #FluorescenceFriday @_atanas_ @simongerman600 @grawoig @NovogeneLS https://t.co/NICzBeewiZ

Nov 8, 2019 · 27 likes · 18 shares · 39,372 followers View post →
Yara Sanchez Corrales
@DrYaraSanchez · X

Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall McDole et al., 2018 (https://t.co/oiuiBmCfHm), where a convolutional neural network (#CNN). was used to find diving cells. Please RT. Thanks!

Jan 27, 2020 · 9 likes · 9 shares · 2,011 followers View post →
Dagmar Iber
@DagmarIber · X

We think that because of the low mesoderm area in caudal regions, the embryo requires #zippering to fully close its #neuraltube. Movie with closure+zippering from our wonderful co-author Katie McDole, previously published in @CellCellPress: https://t.co/h3IivOsdWo https://t.co/z065Z5wxGt

Oct 24, 2021 · 9 likes · 2 shares · 1,481 followers View post →
Kay Schink
@kschink · X

@ManuelTHERY @preibischs And this one from the Keller lab should have similar movies from mice : https://t.co/LIfoxqlNeR

Feb 12, 2021 · 2 likes · 1,322 followers View post →
Adrián Candelas
@adriancandelas · X

Here the new Bible: https://t.co/xoReaR5jPR

Oct 18, 2022 · 1 like · 1 share · 711 followers View post →
DZ Gong | 龚 | ゴン | 공
@dz_gong · X

Paper read today #275: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level #LightSheet 10.1016/j.cell.2018.09.031 A light-sheet microscope adapts itself to the changes in size, shape, and optical properties of the mouse embryo. https://t.co/xfcmrllz0E

Feb 9, 2023 · 1 like · 1 share · 622 followers View post →

All mentions

Petra Kučerová
@Peta_Kucerova · X

RT @dz_gong: Paper read today #275: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level #Lig…

Feb 10, 2023 · 1 share · 46 followers View post →
DZ Gong | 龚 | ゴン | 공
@dz_gong · X

Paper read today #275: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level #LightSheet 10.1016/j.cell.2018.09.031 A light-sheet microscope adapts itself to the changes in size, shape, and optical properties of the mouse embryo. https://t.co/xfcmrllz0E

Feb 9, 2023 · 1 like · 1 share · 622 followers View post →
fabrice senger
@fabrice_senger · X

RT @adriancandelas: Here the new Bible: https://t.co/xoReaR5jPR

Oct 18, 2022 · 1 share · 840 followers View post →
Adrián Candelas
@adriancandelas · X

One more… McDole et al., 2018 https://t.co/SkdwkLTSye

Oct 18, 2022 · 711 followers View post →
Adrián Candelas
@adriancandelas · X

Here the new Bible: https://t.co/xoReaR5jPR

Oct 18, 2022 · 1 like · 1 share · 711 followers View post →
Jinglei Zhai, 晶磊 翟
@jingleidi · X

RT @DagmarIber: We think that because of the low mesoderm area in caudal regions, the embryo requires #zippering to fully close its #neural…

Aug 15, 2022 · 2 shares · 45 followers View post →
Susan Lowell de Solórzano
@1Biotensegrity · X

RT @DagmarIber: We think that because of the low mesoderm area in caudal regions, the embryo requires #zippering to fully close its #neural…

Oct 24, 2021 · 2 shares · 2,020 followers View post →
Dagmar Iber
@DagmarIber · X

We think that because of the low mesoderm area in caudal regions, the embryo requires #zippering to fully close its #neuraltube. Movie with closure+zippering from our wonderful co-author Katie McDole, previously published in @CellCellPress: https://t.co/h3IivOsdWo https://t.co/z065Z5wxGt

Oct 24, 2021 · 9 likes · 2 shares · 1,481 followers View post →
RRID Robot
@RobotRrid · X

The authors of "In Toto Imaging and Reconstruction of Post-Implant…" (https://t.co/udYQMl9HVi) included RRIDs in their paper! Thank you for making your #methodsmatter. #reproducibility

Sep 6, 2021 · 161 followers View post →
Kay Schink
@kschink · X

@ManuelTHERY @preibischs And this one from the Keller lab should have similar movies from mice : https://t.co/LIfoxqlNeR

Feb 12, 2021 · 2 likes · 1,322 followers View post →
Erika Tsingos
@tisrenk · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 28, 2020 · 9 shares · 300 followers View post →
Araújo Lab
@AraujolabUB · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 1,201 followers View post →
Will Hill
@DrWilliamHill · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 1,288 followers View post →
Assaf Zaritsky
@AssafZaritsky · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 1,626 followers View post →
A
@AnnaBajur · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 992 followers View post →
Luisma Escudero
@lmescu · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 4,987 followers View post →
Dr Matt Benton
@DrMattBenton · X

RT @DrYaraSanchez: Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall…

Jan 27, 2020 · 9 shares · 1,167 followers View post →
Yara Sanchez Corrales
@DrYaraSanchez · X

Twitter folks: do you know examples of using #ML #deeplearning to extract cell behaviour from images? I can only recall McDole et al., 2018 (https://t.co/oiuiBmCfHm), where a convolutional neural network (#CNN). was used to find diving cells. Please RT. Thanks!

Jan 27, 2020 · 9 likes · 9 shares · 2,011 followers View post →
Sharer UsSharing
@SharerUssharing · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Dec 11, 2019 · 18 shares · 23,790 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Dec 11, 2019 · 18 shares · 6,554 followers View post →
Newyork Fitness
@NewYorkPass · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Dec 11, 2019 · 18 shares · 4,773 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 18, 2019 · 18 shares · 6,554 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 12, 2019 · 18 shares · 6,554 followers View post →
Lommond
@Lommond78 · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 10, 2019 · 18 shares · 96 followers View post →
the reaper
@thparietallobe · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 2,221 followers View post →
Scránny® Strange
@LAVOE_Jonnath · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 923 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 39,372 followers View post →
م. محمد العقيلي
@MohdAlaqeili · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 3,248 followers View post →
Alice Lee
@alee7095 · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 2,193 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 9, 2019 · 18 shares · 10,270 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 8, 2019 · 18 shares · 123,670 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 8, 2019 · 18 shares · 6,554 followers View post →
John Paul Tosoc, PhD
@meJPAUL · X

RT @DNA_RNA_Uni: In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZM…

Nov 8, 2019 · 18 shares · 3,588 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level (2018) https://t.co/ZMZfZroER8 source vid: https://t.co/1wE2YXI1mW #science #biology #microscopy #fluorescence #FluorescenceFriday @_atanas_ @simongerman600 @grawoig @NovogeneLS https://t.co/NICzBeewiZ

Nov 8, 2019 · 27 likes · 18 shares · 39,372 followers View post →
yy26
@yy26 · X

In toto imaging and reconstruction of post-implantation mouse development at the single-cell level https://t.co/36KWRNlmw0

Mar 5, 2019 · 935 followers View post →
sayum
@szayu1 · X

In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level https://t.co/Va2TKgC27v

Jan 12, 2019 · 118 followers View post →
the paper link
@the_paper_link · X

[trend] up+11: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 9, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+5: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 8, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+9: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 6, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+5: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 5, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+3: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 4, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+4: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 3, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+20: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 2, 2019 · 136 followers View post →
the paper link
@the_paper_link · X

[trend] up+14: *McDole K* et al (Cell) **In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level.** https://t.co/y0p4XjRzNt

Jan 1, 2019 · 136 followers View post →