Genome Biol October 2018 PMID 30333059

Chromosome evolution at the origin of the ancestral vertebrate genome.

Christine Sacerdot, Alexandra Louis, Céline Bon, Camille Berthelot, Hugues Roest Crollius

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Mentions

8
Peak: 2 in Sep 2024
across 3 sources since Oct 2018

Extended reach

39,695
potential audience

Total likes

1,251

Video views

30,459

Mentions per month

Oct 2018 – Sep 2024

Where it's discussed

  • X / Twitter5 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The conversations reveal interest in how the research provides evidence for the 2R hypothesis, with comments emphasizing the use of novel methodologies and the evolutionary significance of chromosome linkages, such as the recovery of 17 'chordate linkage groups'. Words like 'remarkable' and 'fundamental' demonstrate an appreciation for the study's contributions, while references to specific techniques show deep engagement with the topic.

AgreementModerate agreement

Most discussions acknowledge the importance of the research, especially those highlighting the confirmation of the two genome duplications in vertebrate evolution.

InterestModerate interest

Participants show moderate interest, with some noting the methodological advancements and the relevance of the findings.

EngagementModerate engagement

The comments demonstrate thoughtful engagement, referencing specific concepts like gene retention/loss, chromosome numbers, and evolutionary hypotheses.

ImpactModerate impact

The debates suggest that the publication influences ongoing discussions about vertebrate origins, indicating a notable impact within the scientific community.

Abstract in brief

  • Researchers reconstructed the early vertebrate genome by comparing 61 modern animal genomes, revealing that it originated from two whole genome duplications in a marine chordate lineage over 450 million years ago.
  • The study traced the evolutionary process showing the ancestral genome initially had 17 chromosomes, which duplicated and fused multiple times, leading to various chromosome counts (up to 54 before some fusions in jawless fish and bony vertebrates), clarifying the events before the divergence of jawed and jawless vertebrates.
  • These findings confirm the two initial whole genome duplications were pivotal in vertebrate evolution, offering insights into how duplicate genes were retained or lost, shaping the genomes of today's vertebrates and resolving previous uncertainties, especially relating to lampreys.]

Top posts

Most liked on X and Bluesky
sal
@sal069010022845 · X

@PetalsPea @connerben @IanHurn0 @Eleventhstar1 Chromosome evolution at the origin of the ancestral vertebrate genome This provides a foundation for studying the evolution of vertebrate chromosomes from the standpoint of a common ancestor & particularly the pattern of DUPLICATE GENE RETENTION & LOSS. https://t.co/8QQUbmVDPX

Sep 3, 2024 · 1 like · 4,166 followers View post →
Belle
@itisjustmebabe · X

@_truthswordsa @timmbosliceeee @LannisterLeo @curtisdaddylove @IngridIngwah @impeachqueen @RebelATliance @Infeterrence @hessenjunge76 @ScientiaPercept @QuantumHawk666 @SecularSmurf @StevenB45193461 @Chortling_Man @NHoomans @DeanoMartino1 @jasonstonenola @D_D_1983 @OnlyaMoment3 @robburdack @GospelOBenjamin @BrianNazarenus @badgervindaloo @1pckt @Ihonestlydont19 @rkdoctr @megafant1 @kester_lowers @ax2n38 @hubie0 @illmakelamb @HaircutSpock @DarkCowboyGod @depth_ocean_ @lostpro65762288 @dirk_fasshauer @orna_verum @EdgeZeto @Melanie33720945 @bumpus_lumpus @twisted_pies @umfpt @InfinitmVeritum @PeteAlonSoCrazy @almcdermid @MucusMucous @AprilLigeia @LeannEAF @JerryMcPhers @parentingtired https://t.co/NjFvuKvXJB

Apr 20, 2023 · 2,994 followers View post →
Bart Klink
@KlinkBart · X

@BorgerPieter Voor wat recente onderbouwing van de 2R-hypothese op grond van genoomanalyses, zie o.a. https://t.co/GulJOW5nlr en https://t.co/60kFBRuCbw

Feb 16, 2022 · 959 followers View post →
Kitefrog
@kitefrog · X

https://t.co/auZYspZsPe

Dec 23, 2022 · 710 followers View post →
Łukasz Sobala
@glycolukasz · X

Previous research (https://t.co/if8sGdVsrZ) suggested that the vertebrate pre-duplication ancestor had 17 chromosomes. Here, using a novel methodology, the authors recovered 17 "chordate linkage groups" (CLGs). I found this quite remarkable.

Apr 29, 2020 · 408 followers View post →
Francesco Santini
@fsantini2015.bsky.social · Bluesky

Chromosome evolution at the origin of the ancestral vertebrate genome https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1559-1

Oct 26, 2018 View post →

All mentions

sal
@sal069010022845 · X

@PetalsPea @connerben @IanHurn0 @Eleventhstar1 Chromosome evolution at the origin of the ancestral vertebrate genome This provides a foundation for studying the evolution of vertebrate chromosomes from the standpoint of a common ancestor & particularly the pattern of DUPLICATE GENE RETENTION & LOSS. https://t.co/8QQUbmVDPX

Sep 3, 2024 · 1 like · 4,166 followers View post →
Belle
@itisjustmebabe · X

@_truthswordsa @timmbosliceeee @LannisterLeo @curtisdaddylove @IngridIngwah @impeachqueen @RebelATliance @Infeterrence @hessenjunge76 @ScientiaPercept @QuantumHawk666 @SecularSmurf @StevenB45193461 @Chortling_Man @NHoomans @DeanoMartino1 @jasonstonenola @D_D_1983 @OnlyaMoment3 @robburdack @GospelOBenjamin @BrianNazarenus @badgervindaloo @1pckt @Ihonestlydont19 @rkdoctr @megafant1 @kester_lowers @ax2n38 @hubie0 @illmakelamb @HaircutSpock @DarkCowboyGod @depth_ocean_ @lostpro65762288 @dirk_fasshauer @orna_verum @EdgeZeto @Melanie33720945 @bumpus_lumpus @twisted_pies @umfpt @InfinitmVeritum @PeteAlonSoCrazy @almcdermid @MucusMucous @AprilLigeia @LeannEAF @JerryMcPhers @parentingtired https://t.co/NjFvuKvXJB

Apr 20, 2023 · 2,994 followers View post →
Kitefrog
@kitefrog · X

https://t.co/auZYspZsPe

Dec 23, 2022 · 710 followers View post →
Bart Klink
@KlinkBart · X

@BorgerPieter Voor wat recente onderbouwing van de 2R-hypothese op grond van genoomanalyses, zie o.a. https://t.co/GulJOW5nlr en https://t.co/60kFBRuCbw

Feb 16, 2022 · 959 followers View post →
Łukasz Sobala
@glycolukasz · X

Previous research (https://t.co/if8sGdVsrZ) suggested that the vertebrate pre-duplication ancestor had 17 chromosomes. Here, using a novel methodology, the authors recovered 17 "chordate linkage groups" (CLGs). I found this quite remarkable.

Apr 29, 2020 · 408 followers View post →
Francesco Santini
@fsantini2015.bsky.social · Bluesky

Chromosome evolution at the origin of the ancestral vertebrate genome https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1559-1

Oct 26, 2018 View post →