Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsible for 10-20% https://t.co/LVLa2frIzO “Unlike intramuscular free testosterone, dihydrotestosterone, or 5α-reductase, there was a linear relationship
Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy in Healthy, Young Men.
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Feb 2019 – Nov 2025Where it's discussed
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AI synopsis
What people are saying
Several discussions explore the key idea that androgen receptor content is more critical for muscle hypertrophy than systemic hormone levels. For example, comments like "Androgen receptor expression is responsible for 80-90% of strength" and criticisms of the outdated focus on testosterone emphasize the shift in understanding brought by the article. The use of assertive language like 'debunked' and 'must consider' showcases the urgency and importance participants attribute to these findings, indicating a desire to revise longstanding beliefs in the fitness community.
The majority of discussions express alignment with the article's findings that androgen receptors play a crucial role in muscle growth over systemic hormones.
Users demonstrate high interest and curiosity about the implications of the study, often referencing it and related research.
Many participants engage deeply by debating methodologies, sharing supporting studies, and discussing the implications of the findings on training practices.
The discussions highlight the perceived significant impact of the research on understanding muscle hypertrophy and resistance training.
Abstract in brief
- There is significant variability in muscle growth (hypertrophy) among individuals following resistance exercise, but the exact reasons are not fully understood.
- A study analyzed various hormones related to muscle growth before and after 12 weeks of resistance exercise in trained men, but no individual hormone showed a consistent link to muscle growth across participants.
- The findings suggest that the content of androgen receptors within muscle may be more important for muscle mass increases than circulating hormones, as higher receptor levels correlated with greater gains in muscle size.
Top posts
Most liked on X and Bluesky@shoimakoga 運動後のコルチゾール(COR)変化と筋肥大については、”関係性が無い”や逆に相関する(COR濃度が筋肥大と関係する)という報告もあるので、そもそも単回運動に伴うCOR上昇が筋肥大を抑制する仮説には懐疑的です。60分以上の筋トレではないですが。。https://t.co/1wdVa4pOeL https://t.co/JZikRpdm8S
運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は関与していないというのが我々のスタンスです
@shomer_ben @PrimaryCarePAC @drgabriellelyon Here's a few more papers... https://t.co/Rlmfc8JCMv https://t.co/5AmUAGwbr6 https://t.co/XZrdnHyh2R https://t.co/D7h9lQgIab https://t.co/ATTZDyL24a https://t.co/L1mi8jV01I Strength and hypertrophy with resistance training: chasing a hormonal ghost There are more...
Unless you are clinically low in T, raising it some (but still within physiologically normal ranges) isn’t likely to do anything for your physique For best results, train to stimulate adaptations to training, not to spur transient hormonal release https://t.co/m7xSYjcneH
@LazarevskiJovan @hubermanlab @DuncanFrench @UFCPI @BioLayne @DrAndyGalpin Rises in these hormones are a stress response and play no meaningful role in strength or muscle development https://t.co/8qcrKFJAf3 https://t.co/L1mi8jV01I https://t.co/UjCO6KfZsS https://t.co/woH4oPqpt0 https://t.co/CiETabZ83l https://t.co/3Ch2VZFN9P
All mentions
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Biomarkers and Their Role in Muscle Hypertrophy Prediction
This study investigates biomarkers associated with thigh muscle growth after 12 weeks of resistance training. It highlights the complexity of predicting individual responses to training based on biological markers.
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筋肥大にかなり重要。ホルモン受容体を増やす食事栄養・トレーニング方法。
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Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy in Healthy, Young Men https://t.co/Lm0nO9ZQmG
RT @mackinprof: @shomer_ben @PrimaryCarePAC @drgabriellelyon Here's a few more papers... https://t.co/Rlmfc8JCMv https://t.co/5AmUAGwbr6 ht…
RT @mackinprof: @shomer_ben @PrimaryCarePAC @drgabriellelyon Here's a few more papers... https://t.co/Rlmfc8JCMv https://t.co/5AmUAGwbr6 ht…
RT @mackinprof: @shomer_ben @PrimaryCarePAC @drgabriellelyon Here's a few more papers... https://t.co/Rlmfc8JCMv https://t.co/5AmUAGwbr6 ht…
@shomer_ben @PrimaryCarePAC @drgabriellelyon Here's a few more papers... https://t.co/Rlmfc8JCMv https://t.co/5AmUAGwbr6 https://t.co/XZrdnHyh2R https://t.co/D7h9lQgIab https://t.co/ATTZDyL24a https://t.co/L1mi8jV01I Strength and hypertrophy with resistance training: chasing a hormonal ghost There are more...
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
RT @BowTiedUM: Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsibl…
Androgen receptor expression is responsible for 80-90% of strength and muscle gains Testosterone levels are only responsible for 10-20% https://t.co/LVLa2frIzO “Unlike intramuscular free testosterone, dihydrotestosterone, or 5α-reductase, there was a linear relationship
@wellsy13 @TypingOfTheRed @sharrond62 @AnthonyBibbs19 I would argue against a DSD being a health condition, but that's not germane. They *can* have health implications. Commonalities in diagnoses do not equate to how the diagnosis presents on an individual. There is debate about testosterone. https://t.co/q4Cu99c6Fi
RT @SFujita77: 運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は…
RT @SFujita77: 運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は…
RT @SFujita77: 運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は…
RT @SFujita77: 運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は…
運動実施に伴うIGF-1の役割については、近年は特に血管新生に伴う↑脳血流↑認知力が注目されているように思います。 https://t.co/DjZQ9dR0od 美容に関してはエビデンスが不十分で分かりませんが、少なくとも筋肥大にはIGF-1は関与していないというのが我々のスタンスです
@6reathe1 @MrMench76 @cursxd_ang3l @OvOBrezzzy https://t.co/kTYA6oq7Da
Unless you are clinically low in T, raising it some (but still within physiologically normal ranges) isn’t likely to do anything for your physique For best results, train to stimulate adaptations to training, not to spur transient hormonal release https://t.co/m7xSYjcneH
RT @mackinprof: @LazarevskiJovan @hubermanlab @DuncanFrench @UFCPI @BioLayne @DrAndyGalpin Rises in these hormones are a stress response an…
RT @mackinprof: @LazarevskiJovan @hubermanlab @DuncanFrench @UFCPI @BioLayne @DrAndyGalpin Rises in these hormones are a stress response an…
@LazarevskiJovan @hubermanlab @DuncanFrench @UFCPI @BioLayne @DrAndyGalpin Rises in these hormones are a stress response and play no meaningful role in strength or muscle development https://t.co/8qcrKFJAf3 https://t.co/L1mi8jV01I https://t.co/UjCO6KfZsS https://t.co/woH4oPqpt0 https://t.co/CiETabZ83l https://t.co/3Ch2VZFN9P
@hubermanlab @DuncanFrench @UFCPI Truly disappointing! That concept has been consistently debunked. It's an antiquated thought process and just simply untrue! https://t.co/6oleUfeJ0v https://t.co/L1mi8jV01I https://t.co/rQRwemdpiF https://t.co/bINwlhYEMN https://t.co/fBJd3JEgpO https://t.co/hUB8X24DiK
RT @SFujita77: 筋肥大に関する個人差については我々の以下の2つの先行研究も是非ご参照下さい: https://t.co/t1bJpGzqMi https://t.co/1wdVa4pOeL
RT @SFujita77: 筋肥大に関する個人差については我々の以下の2つの先行研究も是非ご参照下さい: https://t.co/t1bJpGzqMi https://t.co/1wdVa4pOeL
メモ https://t.co/52TIEBtMYB
RT @SFujita77: 筋肥大に関する個人差については我々の以下の2つの先行研究も是非ご参照下さい: https://t.co/t1bJpGzqMi https://t.co/1wdVa4pOeL
RT @SFujita77: 筋肥大に関する個人差については我々の以下の2つの先行研究も是非ご参照下さい: https://t.co/t1bJpGzqMi https://t.co/1wdVa4pOeL
筋肥大に関する個人差については我々の以下の2つの先行研究も是非ご参照下さい: https://t.co/t1bJpGzqMi https://t.co/1wdVa4pOeL
@LanesraMark But they’re wrong about the connection between T levels and muscle growth. Why do I say that? Because here’s the evidence testing this idea: https://t.co/88c1mxPjzJ
@OlegKulikov19 As I said in the tweet, supraphysiological levels of testosterone boost muscle growth. But T levels don’t seem to matter at all if they’re in the normal range. https://t.co/88c1mxPjzJ
Bad reception: "These results indicate that intramuscular androgen receptor content, but neither circulating nor intramuscular hormones, influence skeletal muscle hypertrophy following resistance training in previously trained young men." https://t.co/7U6FncStBl
RT @Touhara_sci: トレーニング中のテストステロン値のわずかな上昇は長期的な筋肥大に影響しない可能性が高い。これは確かAthletebodyの記事でまとめられていた。 一方でこの論文ではテストステロンの受容体が多い人がいわゆる”イージーゲイナー”な傾向にあると示唆…
RT @Touhara_sci: トレーニング中のテストステロン値のわずかな上昇は長期的な筋肥大に影響しない可能性が高い。これは確かAthletebodyの記事でまとめられていた。 一方でこの論文ではテストステロンの受容体が多い人がいわゆる”イージーゲイナー”な傾向にあると示唆…
トレーニング中のテストステロン値のわずかな上昇は長期的な筋肥大に影響しない可能性が高い。これは確かAthletebodyの記事でまとめられていた。 一方でこの論文ではテストステロンの受容体が多い人がいわゆる”イージーゲイナー”な傾向にあると示唆している。 https://t.co/LhSIwzM0Bn https://t.co/kVROaXRaHh
@BioPhysChemMark @FoodFirst_Ty @Race__Realist @rdbsmiles @DaveKeto @DoctorTro @BioLayne Testosterone is complicated. Alarmingly low T levels found in elite athletes showing no signs of low T here https://t.co/h7otCPUplO. Baker doesn’t really show signs of low T. Perhaps muscle androgen receptors are a better indicator than free serum T levels https://t.co/KVTHPfBpMu
RT @SFujita77: @shoimakoga 運動後のコルチゾール(COR)変化と筋肥大については、”関係性が無い”や逆に相関する(COR濃度が筋肥大と関係する)という報告もあるので、そもそも単回運動に伴うCOR上昇が筋肥大を抑制する仮説には懐疑的です。60分以上の筋ト…
RT @SFujita77: @shoimakoga 運動後のコルチゾール(COR)変化と筋肥大については、”関係性が無い”や逆に相関する(COR濃度が筋肥大と関係する)という報告もあるので、そもそも単回運動に伴うCOR上昇が筋肥大を抑制する仮説には懐疑的です。60分以上の筋ト…
RT @SFujita77: @shoimakoga 運動後のコルチゾール(COR)変化と筋肥大については、”関係性が無い”や逆に相関する(COR濃度が筋肥大と関係する)という報告もあるので、そもそも単回運動に伴うCOR上昇が筋肥大を抑制する仮説には懐疑的です。60分以上の筋ト…
@shoimakoga 運動後のコルチゾール(COR)変化と筋肥大については、”関係性が無い”や逆に相関する(COR濃度が筋肥大と関係する)という報告もあるので、そもそも単回運動に伴うCOR上昇が筋肥大を抑制する仮説には懐疑的です。60分以上の筋トレではないですが。。https://t.co/1wdVa4pOeL https://t.co/JZikRpdm8S
RT @SekretSila: Es bastante importante, porque en cuestión de crecimiento muscular, el problema no es tanto los niveles de testosterona, qu…
RT @osaid422: قاعدة علمية : كلام الأشخاص يستدل له ولا يستدل به ، لأن العبرة بالعلم وليس " بالبطل " ، غير أن جورج فرح له أخطاء كثيرة علمية ت…
قاعدة علمية : كلام الأشخاص يستدل له ولا يستدل به ، لأن العبرة بالعلم وليس " بالبطل " ، غير أن جورج فرح له أخطاء كثيرة علمية تكلم عنها وجاب العيد ، إرتفاع التيستوستيرون والقروث هرمون بعد التمرين ، ليس له علاقة بزيادة الكتلة العضلية مطلقاً https://t.co/tc8cYj1Cii https://t.co/HUaXNkZZ5N
Es bastante importante, porque en cuestión de crecimiento muscular, el problema no es tanto los niveles de testosterona, que por lo general los jóvenes los tienen por las nubes, sino la sensibilidad a la testosterona de tu cuerpo. https://t.co/CewQumuW73
@ap_coach @GDLeahy @EricRawsonPhD @jploenneke @ShawnArent in humans too: https://t.co/fBJd3JEgpO https://t.co/xdzv754VuX but it's way more complicated than just AR... if reviewers ever let us publish!
@Mangan150 Human data: https://t.co/V1GFg3zLAR https://t.co/fBJd3JEgpO intramuscular androgen receptor content, but not circulating nor intramuscular hormones (or enzymes regulating their production), influence skeletal muscle hypertrophy following RET in previously trained young men.
@Fanfoot002 @BioLayne @SBakerMD He was probably referring to this paper by Dr. Phillips group that recently showed high responders to RET had higher levels of androgen receptor expression in lean tissue than low responders. But acute responses don’t = long term diffs... https://t.co/MBLZvCRUSw
@CarnivoreMD listening to lab tests podcast. You asked for citation... Muscle Androgen Receptor Content Not Systemic Hormones Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy https://t.co/s8JhDSLtdD
@RedPillVegan @JTMarlin77 @Drgarthdavis @BioLayne https://t.co/olxAjlof9t study I referenced- in natural athletes receptor >>> hormone level- However is you are on gear then that also stimulates receptor increase, that’s why bodybuilders keep getting bigger
RT @mackinprof: Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle H…
@NanciGuestRDPhD @JadamJay I had a similar conversation earlier today specifically about T levels. This recent study came to my mind showing it’s not all about hormones but the receptors may play a larger role than we once thought. Still an advantage for bio men I would think. https://t.co/gHXBwlkxyI
@richcollins @DrSepah @professionaldog @robtrumpetsmith @MatthewJDalby @KetoCarnivore @chaszero @ZeroCarbHealth @kelly_hogan_zc https://t.co/olxAjlof9t this 2018 study is relevant in non PED athletes
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