January 2019 PMID 30415628

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.

Deepak L Bhatt, P Gabriel Steg, Michael Miller, Eliot A Brinton, Terry A Jacobson, Steven B Ketchum, Ralph T Doyle, Rebecca A Juliano, Lixia Jiao, Craig Granowitz, Jean-Claude Tardif, Christie M Ballantyne

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Mentions

528

Peak: 53 in Jan 2019

across 6 sources since Jan 2019

Extended reach

3,457,383

potential audience

Total likes

26,039

Video views

1,100,516

Mentions per month

Jan 2019 – Nov 2025

Where it's discussed

X / Twitter222 posts
News208 articles
Facebook47 posts
Blogs28 articles
YouTube19 videos
Reddit4 posts

AI synopsis

What people are saying

The consensus among discussions is highly positive, with examples like references to the REDUCE-IT trial's 25% reduction in cardiovascular events, the use of 4g daily EPA, and comments labeling the study as 'game-changing'. Words such as 'beneficial', 'important', and 'breakthrough' convey enthusiasm, while mentions of specific results and trial details indicate in-depth engagement. The tone and language collectively reflect a perception that this research has a profound impact on cardiovascular health management.

AgreementStrong agreement

Most discussions highlight strong support and agreement with the study’s findings, emphasizing the cardiovascular benefits of icosapent ethyl and referring to the trial as groundbreaking evidence.

InterestHigh interest

Posts demonstrate high interest, with frequent mentions of study details, clinical trial results, and implications for treatment, reflecting active engagement with the topic.

EngagementHigh engagement

Many comments delve into specifics like dosage, trial design, and clinical applications, indicating deep engagement and critical analysis.

ImpactHigh impact

The overall tone suggests that the publication could significantly influence clinical practice and public awareness about cardiovascular risk reduction, as evidenced by references to guidelines, policy implications, and widespread citations.

Abstract in brief

The study investigated whether icosapent ethyl, a purified form of omega-3 fatty acid, can reduce the risk of cardiovascular events in patients with high triglycerides who are already on statins.
Results showed that patients taking 2 grams of icosapent ethyl twice daily had significantly fewer cardiovascular events, including death, heart attacks, strokes, and related procedures, compared to those taking a placebo.
Overall, the findings suggest that icosapent ethyl not only lowers triglyceride levels but also provides substantial protection against ischemic cardiovascular events in high-risk patients.

Read the full abstract

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Woodruff Health Sciences Center Library

@EmoryHealthLibr · X

Drs. Jacobson's highest cited "Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia" & Eun-Hyung highest cited, "Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease." @EmoryDeptofMed @EmoryMedicine @emoryhealthsci @emoryhealthcare https://t.co/ZL9YTmKdyD

Nov 21, 2025 · 2 likes · 638 followers View post →

cardio-met

@cardiomet_CE · X

13a) Re #IPE, there were new data from #REDUCE_IT. These built on the 2018 primary results from that trial,

Oct 21, 2025 · 1 like · 4,221 followers View post →

Lê Văn Lắm

@levanlam95 · X

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia | New England Journal of Medicine https://t.co/fOVuUJOOkb

May 5, 2025 · 42 followers View post →

Tom Hyde

@CotsCardiology · X

This looks interesting, wonder if there were any imaging substudies in REDUCE IT ? @PMccoubrie may know? https://t.co/VXTHmUawxr https://t.co/AAhkcU1XL2

Apr 4, 2025 · 1 like · 1,560 followers View post →

Tom Hyde

@CotsCardiology · X

@lowcarbGP @DrScottMurray Association is not necessarily causation. Is there robust evidence that lowering triglycerides reduces mortality. There is one trial I can think of that showed this, any others you know of ? https://t.co/VXTHmUawxr

Apr 4, 2025 · 1 like · 1,560 followers View post →

やまだ@腸活×アンチエイジング

@tarou_ymd_ · X

一方で、REDUCE-IT試験（2019年, NEJM）では、純粋なEPA製剤（イコサペントエチル）が高リスク患者の2次予防に有効とされたが、これは高濃度のEPA（1日4g）かつ処方薬であり、一般的な魚油サプリとは別物。 https://t.co/Bx053NIibs

Mar 27, 2025 · 1 like · 6,121 followers View post →

ほどほど

@taka_hiro32 · X

https://t.co/LNGfbVEMKa

Mar 24, 2025 · 1 like · 859 followers View post →

Dan Pike

@bigpiclongterm · X

@Comm_Invest There was a study out of Harvard Med School ~10 years ago showing that EPA component of Omega3 fish oil has a significant effect in reducing systemic inflammation, with a huge benefit for those at risk of cardiac disease. Been taking 3 gr/day for 5+ years. https://t.co/uxvmABIvZ1

Feb 6, 2025 · 2 likes · 573 followers View post →

مقاومة الانسولين insulin resistance

@insulin_resista · X

@mm9qqq @meowmemes1 https://t.co/replBXqkeU

Jan 20, 2025 · 30,376 followers View post →

Oskar

@notoskarisaak · X

@0___Abraxas___0 https://t.co/7SWs5Q57Tv

Dec 4, 2024 · 603 followers View post →

Not Pedro

@notpedropaskal · X

@0___Abraxas___0 https://t.co/7SWs5Q57Tv

Dec 4, 2024 · 639 followers View post →

Fizz-DI＠比較と使い分け-KOJIMA Yushi

@Fizz_DI · X

1) N Engl J Med . 2019 Jan 3;380(1):11-22. https://t.co/oL9UtgtALV 3) JAMA . 2020 Dec 8;324(22):2268-2280. https://t.co/D3gl38EpWK ↑どっちも海外の高用量（4,000mg）の話だし、でこれまで流し気味だったけど、↓国内の1,800mgのRCTでも同じ傾向が出てきて、確かにﾑﾑﾑ…となっている

Nov 13, 2024 · 6 likes · 34,291 followers View post →

TEKEL

@ewilliams30102 · X

@RobertKennedyJr $amrn was destoryed by the FDA and the benifits of VASCEPA has been hiden from the general public. It's almost like FDA dosn't want affective drugs without side affects on the market. https://t.co/TVnhsPci3d

Nov 11, 2024 · 390 followers View post →

Charles Cardone

@CharlesCardone · X

RT @GeoWizz_: @Drlipid @johnrroberts3 @nationallipid @society_eas @escardio As stated by @Drlipid, "it's best to look at MACE Reduction rat…

Aug 30, 2024 · 1 share · 79 followers View post →

Mike Everts

@GeoWizz_ · X

@Drlipid @johnrroberts3 @nationallipid @society_eas @escardio As stated by @Drlipid, "it's best to look at MACE Reduction rather than plaque imaging changes." You can see both with IPE (icosapent ethyl) intervention. EVAPORATE RCT: Plaque Reduction, https://t.co/k78iidohsu REDUCE-IT RCT: MACE Reduction, https://t.co/xJw7roaa1W

Aug 30, 2024 · 4 likes · 1 share · 428 followers View post →

くすりの家庭教師 ™奥村友紀【公式】

@tak_pom · X

RT @tak_pom: Bhatt DL, et al. for the REDUCE-IT Investigators: Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia…

Aug 29, 2024 · 2 shares · 12,930 followers View post →

I don't know much

@paquibena · X

RT @ReformedTrader: Is fish oil giving you Heart Disease?! "A new study suggests that fish oil raises risk of a heart disease called atria…

Jul 14, 2024 · 1 share · 268 followers View post →

Darren

@ReformedTrader · X

Is fish oil giving you Heart Disease?! "A new study suggests that fish oil raises risk of a heart disease called atrial fibrillation. Is the conclusion real or bogus?" https://t.co/hx6VOx0YV6

Jul 14, 2024 · 3 likes · 1 share · 14,870 followers View post →

DaRocDok.com®

@DaRocDok · X

Is fish oil giving you Heart Disease?! https://t.co/DmLMa4o035 via @YouTube

Jul 3, 2024 · 1,520 followers View post →

Ravi

@sweetchillysaus · X

https://t.co/ImlbyC3FbP

Jul 2, 2024 · 46 followers View post →

Supawat Jindawatt

@SBJindawatt · X

Is fish oil giving you Heart Disease?! https://t.co/dQG4Eo9ARi via @YouTube

Jul 2, 2024 · 6 followers View post →

Gil Carvalho MD PhD

@NutritionMadeS3 · X

https://t.co/UJOnNRPWqz

Jul 1, 2024 · 4 likes · 27,712 followers View post →

Dr. Ozan Ünlü

@DrOzanUnlu · X

Referanslar

Jun 22, 2024 · 8 likes · 36,655 followers View post →

أ.د خالد فايز الحبيب

@KhalidFAlhabib · X

@ydlrby10515126 https://t.co/sUY8PefdHe

May 11, 2024 · 16,733 followers View post →

unimusashi（N. Ashikawa）

@uni_pharmacist · X

@Toki_nd2525 無くはないけど、処方提案する機会は無さそう... https://t.co/xiDwAuh8NC https://t.co/JVthmBwjb9

Apr 13, 2024 · 2 likes · 1,335 followers View post →

影山　広行

@ultimumveritas · X

REDUCE-ITの被験者は心脳血管疾患、糖尿病、その他のリスクが有り、スタチンが入っていて、高中性脂肪血症でなど一定の傾向を持っています。 https://t.co/gZPQmyfG99 (p45) https://t.co/3y6gd8IbXa

Apr 9, 2024 · 1 like · 959 followers View post →

影山　広行

@ultimumveritas · X

JELIS, 2007 https://t.co/BiAiPdni4m REDUCE-IT, 2018 https://t.co/viSyWKNkLi JERISの方が人数が多く、観察期間に大きな差はないのに、REDUCE-ITの方が四角が大きく、信頼区間が短く、weightが高いのはサンプルサイズ大きい（ばらつきが小さい）ことが理由です https://t.co/w7Z1lVUe54 https://t.co/rYwIev8aXH

Mar 15, 2024 · 2 likes · 959 followers View post →

影山　広行

@ultimumveritas · X

この研究の参加者の流れを示します。 https://t.co/KsFDf1vUEj (p46) CONSORT声明という臨床試験において記載されるべき項目のチェックリストがあります。 https://t.co/4WzTsx7fLV (p2,3) 参加者のフォロチャートの作成の推奨、作成の方法も具体的に示されています。 https://t.co/T639h5q569

Feb 22, 2024 · 1 like · 959 followers View post →

影山　広行

@ultimumveritas · X

今回の研究は Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT) と呼ばれています。研究の構成もわかりやすく整理されていますね。 https://t.co/KsFDf1vUEj　(p45) https://t.co/v22Jx6reiw

Feb 21, 2024 · 1 like · 959 followers View post →

Alexander B Parra Finol

@LuckasSalomon · X

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia | NEJM https://t.co/XyPuCjXEZw

Feb 21, 2024 · 505 followers View post →

影山　広行

@ultimumveritas · X

２つのネガティブ・スタディー（仮説が証明されない研究）で疲れましたね。次はどうでしょう。高中性脂肪血症の患者にEPAを投与すると心血管リスクが低下するかどうかについてです。 Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia https://t.co/viSyWKNkLi

Feb 19, 2024 · 2 likes · 959 followers View post →

kt - people

@PreciouSmileV · X

https://t.co/xTKBK5mJIL

Feb 12, 2024 · 241 followers View post →

Holmes1618

@Holmes1618 · X

@fmfclips to complete the picture, the study was published in 2019? this one? https://t.co/uDGZzlcBgD https://t.co/iLWXym5CXd

Jan 26, 2024 · 2 likes · 3,290 followers View post →

Holmes1618

@Holmes1618 · X

REDUCE-IT Trial with EPA Fish Oil (4g daily) Result (N Engl J Med 2019): 20 to 25% reduction in MACE and CD while the absolute increase in AF risk was 1.4%. https://t.co/uDGZzlcBgD This was the first large-scale trial to show a significant cardiovascular benefit of EPA beyond https://t.co/XmO0qlOwzP

Jan 26, 2024 · 2 likes · 3,290 followers View post →

Dr. Sou

@SwissHeartDoc · X

The outcome data https://t.co/F6ocJACgab https://t.co/XOFHKXBH6C

Jan 25, 2024 · 4 likes · 882 followers View post →

Sigbee

@Sigbee · X

@AlpacaAurelius https://t.co/Ezr1oGKwVf

Jan 11, 2024 · 52 followers View post →

Oskar

@notoskarisaak · X

@JulioBasulto_DN @drjohnm @Medscape https://t.co/7SWs5Q57Tv

Dec 17, 2023 · 603 followers View post →

Not Pedro

@notpedropaskal · X

@JulioBasulto_DN @drjohnm @Medscape https://t.co/7SWs5Q57Tv

Dec 17, 2023 · 639 followers View post →

Mike Everts

@GeoWizz_ · X

RT @theindianheart: ACC Trial Summary : https://t.co/Jhv709519z NEJM full article open access #FOAMed : https://t.co/TrZYGAxOZX

Dec 11, 2023 · 1 share · 428 followers View post →

Indian Heart Association

@theindianheart · X

ACC Trial Summary : https://t.co/Jhv709519z NEJM full article open access #FOAMed : https://t.co/TrZYGAxOZX

Dec 11, 2023 · 3 likes · 1 share · 1,132 followers View post →

Sigbee

@Sigbee · X

@ifbacongrewont1 @calleymeans Not true. https://t.co/Ezr1oGKwVf

Nov 23, 2023 · 52 followers View post →

Sigbee

@Sigbee · X

@zbingledack @calleymeans https://t.co/Ezr1oGKwVf The reason people don't know about it is because big pharma does not own it yet. Please see this 5 year trial. The results are phenomenal. Me and my entire family take this daily as we have heart disease in our family.

Nov 22, 2023 · 2 likes · 52 followers View post →

Prof Chris P Gale

@cpgale3 · X

@gonzaeperez @ESC_Journals @DLBHATTMD @SIAC_cardio @siacprevent @DrPontecarlosi @rigotordoc @cingolani_oscar @SeguraCardio @ValleAlfonso @ezeforte @sigal_alan @jpcostabel My concerns are the ⬆️ rates of

Oct 28, 2023 · 5 likes · 13,470 followers View post →

Science Collected

@ScienceCollect1 · X

21/

Oct 24, 2023 · 124 followers View post →

Science Collected

@ScienceCollect1 · X

19/

Oct 24, 2023 · 124 followers View post →

DoctorTro

@DoctorTro · X

One more time https://t.co/lP4lpQARSe

Aug 17, 2023 · 160,515 followers View post →

DoctorTro

@DoctorTro · X

Link: https://t.co/lP4lpQARSe

Aug 17, 2023 · 1 like · 160,515 followers View post →

mik

@kpsb666 · X

@syuichiao89 https://t.co/LO4IFRrVJ8 DHAは諸説ありだけどEPA supplementationは結論出てるのでは？

Aug 12, 2023 · 382 followers View post →

EmoryGIM

@EmoryGIM · X

Thrilled to see @EmoryGIM colleague Terry Jacobson recognized as one of @EmoryDeptofMed top 100 researchers based on articles, citations, impact, & H-index! #gamechangingresearch #cardiometabolichealth #GIMresearch @nationallipid @CMHC_CME https://t.co/mDGCwb6cEI https://t.co/U3usVK318I

Jul 26, 2023 · 7 likes · 278 followers View post →

DrLJ

@drlaurajane · X

@psmedic @EmergMedDr @Microbedoc2 @huel @shireenkassam1 The more recent well designed REDUCE-IT trial @NEJM showed benefits of icosapent ethyl (highly purified EPA) - 8000 patients, 4.9yrs. Lower CV death in those with high triglycerides despite statin in intervention arm https://t.co/ztOoyPnNkO 6/n

May 21, 2023 · 2 likes · 5,175 followers View post →

ガラパゴス伊藤@総合診療医

@galapagos_ito · X

EPAに関しては微妙。確かにREDUCE-IT試験では心血管イベント減らしてるけど、他の研究で類似の結果が出ていない。 Up To Dateだと心血管ハイリスクに対してはGrade2Bで推奨。今のとこははっきりしないって感じかな。新しくは処方しないけど、中止もしないってくらい。 https://t.co/IfZOnsGm8X

Mar 26, 2023 · 5 likes · 2,402 followers View post →

Pranab Chatterjee

@scepticemia · X

@theliverdr So, icosapent ethyl is used to reduce cardiovascular risk (not the same as w3, is a prescription drug). Not sure if it’s approved for use in India? https://t.co/ziJBxbZCuZ Could likely be a more effective and safe alternative.

Mar 2, 2023 · 1 like · 1 share · 3,308 followers View post →

Frank Arsenyadis

@DietitianUK · X

Main trial evidence here, interesting to see how/if depression outcomes are at all affected https://t.co/xs8AGLo7w6

Jan 9, 2023 · 68 followers View post →

Camille

@conatux · X

@JuliaB_fitness @Branko7711 @npure3 @foundmyfitness But in this one published in @NEJM : https://t.co/h5sVBxsKfo, they used pharma grade ethyl ester and found afib

Jan 7, 2023 · 2,087 followers View post →

Yoichiro.S@循環器内科医

@cardio_dr_ys · X

自研究のOCT画像が出たついでにオメガ3脂肪酸の話・RCTの結果からはまだ議論が尽きない・対照群の製剤も問題だった・EPA/DHA製剤ではCV outcome改善せず？・EPAだけで十分量投与すると予後改善かも添付はREDUCE-IT https://t.co/kUyf6SDPU9

Jan 6, 2023 · 1 like · 3,426 followers View post →

Kevin D.

@KevinD50496210 · X

@REV_Insulin_Res @BiggestComeback The control group had an average glucose that never went below 200mg/dL. Here a study showing lowering abnormal triglycerides reduces CV death. It’s not what either of us is interested in but if that’s the standard of evidence you require.. https://t.co/POBhOkrHkf

Dec 27, 2022 · 2 followers View post →

Syed Shaaban

@ShaabanSyed · X

RT @CMichaelGibson: @WorldStrokeOrg @Jan_FriSch @SposatoL @ShadiYaghi2 @adnanalkhouli @DLBHATTMD @POsmancik @guroledip #Vascepa has been sh…

Dec 7, 2022 · 9 shares · 160 followers View post →

Charles Cardone

@CharlesCardone · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 2, 2022 · 8 shares · 79 followers View post →

May's Financial Options

@MayOptions · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 2, 2022 · 8 shares · 37 followers View post →

Medical

@hedgiesinvest · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 2, 2022 · 8 shares · 29 followers View post →

JRooney

@JRoon71 · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 2, 2022 · 8 shares · 31 followers View post →

Lee Robertson

@LeeLrobertson21 · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 2, 2022 · 8 shares · 2 followers View post →

SanDiegoLiving

@Dj_Suv · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 1, 2022 · 8 shares · 6,969 followers View post →

El Conquistador

@MarkBidwell55 · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 1, 2022 · 8 shares · 920 followers View post →

Paul Steele

@peswestford · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 1, 2022 · 8 shares · 708 followers View post →

Litecoinie

@ltcdebit_credit · X

RT @ra_fun: This is dangerous. @fepblue should update their 2023 and cover Vascepa (which reduces CVD by 25%, see link) or stop trying to m…

Dec 1, 2022 · 8 shares · 171 followers View post →

Raf

@ra_fun · X

Dec 1, 2022 · 21 likes · 8 shares · 720 followers View post →

SAEDYN

@SAEDYN_ · X

RT @CristobMorales: Más allá del LDL en el abordaje del Riesgo residual https://t.co/IpjxbrFekJ #UpSAEDYN @SAEDYN_ https://t.co/EH5WIjEirZ

Nov 26, 2022 · 5 shares · 3,775 followers View post →

Carlos Palacio

@CAPE1223 · X

RT @CristobMorales: Más allá del LDL en el abordaje del Riesgo residual https://t.co/IpjxbrFekJ #UpSAEDYN @SAEDYN_ https://t.co/EH5WIjEirZ

Nov 25, 2022 · 5 shares · 1,033 followers View post →

fausto heredia z.

@drfherediaz · X

RT @CristobMorales: Más allá del LDL en el abordaje del Riesgo residual https://t.co/IpjxbrFekJ #UpSAEDYN @SAEDYN_ https://t.co/EH5WIjEirZ

Nov 25, 2022 · 5 shares · 4,350 followers View post →

Henry Gaviria

@henrygav5 · X

RT @CristobMorales: Más allá del LDL en el abordaje del Riesgo residual https://t.co/IpjxbrFekJ #UpSAEDYN @SAEDYN_ https://t.co/EH5WIjEirZ

Nov 25, 2022 · 5 shares · 254 followers View post →

Cristobal Morales

@CristobMorales · X

Más allá del LDL en el abordaje del Riesgo residual https://t.co/IpjxbrFekJ #UpSAEDYN @SAEDYN_ https://t.co/EH5WIjEirZ

Nov 25, 2022 · 5 likes · 5 shares · 17,021 followers View post →

Toshiki Kuno, MD, PhD, FESC, FSCAI

@ToshikiKuno · X

初日のFibrate系のTrialがNegative https://t.co/cZbF4md0O8 であったことから、RESPECT EPAやJELISを踏まえるとStatinを使用してのHTGはEPAがいいとは思います。しかしながらREDUCE ITのPlaceboのMineral oilがhsCRPを増やしてしまったため、懐疑的な部分もあります。 https://t.co/fhPmwQnYZ5

Nov 24, 2022 · 4 likes · 4,260 followers View post →

Jose G. Aray G.

@drjarayg · X

RT @Cardio_delaGuia:

Nov 23, 2022 · 6 shares · 1,144 followers View post →

MercheRC

@rc_merche · X

RT @Cardio_delaGuia:

Nov 23, 2022 · 6 shares · 312 followers View post →

@SVC_FILIALANZOATEGUI

@cardioprevanz · X

RT @Cardio_delaGuia:

Nov 23, 2022 · 6 shares · 827 followers View post →

Nelson murillo

@nemurillob · X

RT @Cardio_delaGuia:

Nov 22, 2022 · 6 shares · 246 followers View post →

СГАМ

@CGAM2016 · X

RT @Cardio_delaGuia:

Nov 22, 2022 · 6 shares · 235 followers View post →

Juan Carlos Obaya

@jcobaya69 · X

RT @Cardio_delaGuia:

Nov 22, 2022 · 6 shares · 856 followers View post →

Fernando de la Guía

@Cardio_delaGuia · X

Nov 22, 2022 · 11 likes · 6 shares · 6,940 followers View post →

Viet Le DMSc PA-C FACC FAHA HF-Cert

@VietHeartPA · X

@neeche41 @lipo_fan @ATHjournal @MichaelJBlaha @CiccaroneCenter @SionRoy @BudoffMd @DLBHATTMD REDUCE-IT Mace outcomes included stroke. From a composite primary interpretation, yes. Reduces stroke. Also impacts risk of subsequent events. https://t.co/DxUPRg34cO #OM3 #EPA https://t.co/iNcE1IehCy

Nov 17, 2022 · 2 likes · 9,787 followers View post →

Claire Davies

@claireyrivs · X

Trial data here: https://t.co/b9HV29uNlu

Nov 16, 2022 · 1,524 followers View post →

くすりの家庭教師 ™奥村友紀【公式】

@tak_pom · X

RT @tak_pom: Bhatt DL, et al. for the REDUCE-IT Investigators: Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia…

Oct 8, 2022 · 2 shares · 12,930 followers View post →

@nagano_1123 · X

原稿関連でREDUCE IT試験を読む。イコサペンタエン酸の容量が日本より多い（4g/day）なのと、スタチンでしっかり治療後の患者が対象なこと、多くは二次予防で使われていることなどが注意点でしょうか。他にツッコミどころあれば教えて下さい。 https://t.co/nSr67gTU5V

Oct 2, 2022 · 5 likes · 5,345 followers View post →

Patricio V. Marquez

@Pvmarquezl · X

Among patients with elevated triglyceride levels despite use of statins,risk of ischemic events,including cardiovascular death,significantly lower among those who received 2 g of icosapent ethyl twice daily than those who received placebo ⁦@NEJM⁩ https://t.co/hy0EC9cC7Y

Sep 5, 2022 · 1 like · 1,585 followers View post →

Everlast Research Group

@EverlastDD · X

@neeche41 @LovingGeneva @skathire @AstraZeneca Can see from REDUCE-IT Table 4 after 1 year for Vascepa that Plasma EPA increased from 26.1ug/mL to 144.0 https://t.co/Yf8kHZfew6 STRENGTH Table 1 and 2 EPA increased from 21 to 89 https://t.co/WN46HQ9NEp Drop in TG is roughly about the same. 41.5 vs 48 vis-a-vis Key: EPA/AA

Aug 22, 2022 · 1 like · 246 followers View post →

Martin Smollich

@ErnMedBlog · X

Aug 4, 2022 · 13 likes · 6,089 followers View post →

Jake Johnson

@JakeJoh34423915 · X

@kevinnbass I don’t think reduce it was included in this. Results made us scratch our heads a bit. https://t.co/XAfqIxxITu

Aug 2, 2022 · 4 followers View post →

Dr Jean Pierre Laroche #vacciné 6.0

@Echoraljpangio · X

RT @SABOURETCardio: Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia. #EPA https://t.co/eByF6xcUHF

Jul 29, 2022 · 1 share · 2,716 followers View post →

SABOURETCardiologist

@SABOURETCardio · X

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia. #EPA https://t.co/eByF6xcUHF

Jul 29, 2022 · 12 likes · 1 share · 31,007 followers View post →

cardio-met

@cardiomet_CE · X

34) #O3FA

Jul 20, 2022 · 3 likes · 4,154 followers View post →

Dr Rahul D Barmanray

@RahulDBarmanray · X

Trouble in (lipid control RCT) paradise... a

Jul 19, 2022 · 5 likes · 378 followers View post →

Jeremy Sussman

@JeremySussman · X

@hmkyale @matthewherper @djc795 Those hsCRP findings were in the original paper, supplementary table 4. To me it feels like the main differences were the primacy and tone with which the authors presented those findings. https://t.co/SLjyGXGZYf

Jul 18, 2022 · 6 likes · 1,948 followers View post →

くすりの家庭教師 ™奥村友紀【公式】

@tak_pom · X

Bhatt DL, et al. for the REDUCE-IT Investigators: Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia. N Engl J Med. 2019; 380: 11-22. https://t.co/XgsdXGU10I https://t.co/AaL8AwYhmg

Jul 15, 2022 · 1 like · 2 shares · 12,930 followers View post →

CornivoreAurelius

@CornivoreA · X

@kevinnbass @PlantChompers @zbitter @drmikehart @AndresPreschel @GavinMeenan https://t.co/n7Fd5V8Vbz

Jun 5, 2022 · 52 followers View post →

Martín Arrieta

@MartinArrM · X

RT @GabrielOliverH2: Riesgo residual CV por hipertrigliceridemia. Moléculas que llegan a quedarse!

May 27, 2022 · 1 share · 169 followers View post →

Gabriel Oliver Hernández

@GabrielOliverH2 · X

Riesgo residual CV por hipertrigliceridemia. Moléculas que llegan a quedarse!

May 27, 2022 · 2 likes · 1 share · 295 followers View post →

Mustafa Alam

@Mustafa_Medical · X

@DLBHATTMD @SCAI @NEJM @NYITCOMDO Latest Analysis From @jaccjournals https://t.co/XzxWS3WEQP Full Trial: https://t.co/2AiuuN3dHa

May 22, 2022 · 3 likes · 129 followers View post →

Irene Caballero

@irenecabmat · X

RT @CristobMorales: https://t.co/5U5YIcUVzS Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia #SedDiab2022 https:…

Apr 29, 2022 · 1 share · 998 followers View post →

Cristobal Morales

@CristobMorales · X

https://t.co/5U5YIcUVzS Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia #SedDiab2022 https://t.co/3pceICO8LE

Apr 29, 2022 · 1 like · 1 share · 17,021 followers View post →

cardio-met

@cardiomet_CE · X

33) REDUCE-IT (

Apr 27, 2022 · 1 like · 4,154 followers View post →

BowTiedLoon | Degen Island Physician

@BowTiedLoon · X

@eviladomiu @JDew116 https://t.co/HuYY0WpVCA

Jan 19, 2022 · 10,958 followers View post →

Bob

@fluxcapdoodah · X

RT @jimtalksdata: REDUCE-IT trial: lessons on how to conduct an effective clinical trial for a so-called "supplement" (EPA fish oil, aka Ic…

Jan 4, 2022 · 1 share · 687 followers View post →

Raf

@ra_fun · X

@DoctorTro And Vascepa also reduces the relative risk of CVD by 25%. https://t.co/1t6CbuV8sK

Jan 2, 2022 · 720 followers View post →

د/عبدالله القرني Abdullah Algarni

@abaidalgarni · X

This conclusion was driven heavily by one positive RCT (REDUCE-IT), which involved an EPA preparation (icosapent ethyl) ALONE in a mainly 2ry-prevention population of statin-treated pts w/ hyperTGemia https://t.co/KJCCFWwVYM https://t.co/HBCZWDdwH0

Dec 28, 2021 · 2,015 followers View post →

Wilhelm Beermann

@WilhelmBeermann · X

'Vascepa' für Patienten https://t.co/5FZZXEbqvB

Dec 13, 2021 · 1 like · 124 followers View post →

mister_snorzud

@mister_snorzud · X

The REDUCE IT Study finally shows the benefits of #omega3 for cardiovascular health. Caution advised: most supplements don't use the correct dosage of EPA / DHA. https://t.co/5fhZoC9bmN

Oct 6, 2021 · 20 followers View post →

Joaquin KM

@joaquinkam · X

@rludym Links to make informed decisions https://t.co/xw85G2nbQm https://t.co/574A4UDfMy https://t.co/Y2flEEDeAk $AMRN $xbi $ibb $qqq $spy

Aug 13, 2021 · 491 followers View post →

عبدالرحمن الشريف

@Aab_alsharif · X

السلام عليكم ورحمة الله وبركاته الاخوة الأعزاء @Saudi_FDA نتمنى منكم تسجيل دواء icosapent ethyl حيث انه من الأدوية الفعالة ونحتاجه بشكل كبير لمرضى ارتفاع الدهون الثلاثية والدراسات العلمية المعتبرة نصحت به لارتفاع الدهون الثلاثية . @aljadhey https://t.co/gCqeYF6c0x

Jul 16, 2021 · 1,048 followers View post →

Orhun Efe

@the_pinebarrens · X

@kardiyobey https://t.co/NdwR61do4d

Jul 9, 2021 · 109 followers View post →

stringercap

@stringercap · X

@ExpectedValues @phanihare @valueterminal Increased seafood consumption likely plays a role given the impact of EPA levels on CV risk https://t.co/Unh9cGrDNv

Jul 7, 2021 · 8 followers View post →

Julia B.

@JuliaB_fitness · X

@DToddWhite @realNathanCheng Well, the Reduce-It trial was ~8200 subjects for ~5 years (4 g EPA daily) (to do that right takes a lot of resources). The company behind it is/was publically listed so they raised a ton of money to do it) (Icosapent Ethyl = EPA ethyl ester). https://t.co/wv3yEd3UJE

Jun 27, 2021 · 2,274 followers View post →

Wildtype

@wildtypefoods · X

Clinical trials investigating Omega-3s have sometimes been inconsistent. But the 2018 REDUCE-IT trial found that EPA (eicosapentaenoic acid) can reduce the rate of cardiovascular disease. https://t.co/qewgzdSu5F 2/

Jun 8, 2021 · 9,681 followers View post →

Sishir Mannava, MD

@SishMannMD · X

Hypertriglyceridemia is an important modifiable stroke risk factor with the advent of new medications for treatment. Below is the REDUCE-IT trial for review: Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia | NEJM https://t.co/tgsijMc2p7

Jun 7, 2021 · 4 likes · 880 followers View post →

Carol Artigas Gomez

@cartigasg · X

RT @WorldStrokeEd: #WeekendLecture #SecondaryPrevention Others: Icosapent Ethyl https://t.co/cEMEiEBSFh Riva+aspirin in #ICAD https://t.co/…

Jun 4, 2021 · 1 share · 630 followers View post →

Nisha Nigil

@nishanigil · X

RT @CMichaelGibson: @WorldStrokeOrg @Jan_FriSch @SposatoL @ShadiYaghi2 @adnanalkhouli @DLBHATTMD @POsmancik @guroledip #Vascepa has been sh…

May 19, 2021 · 9 shares · 1,589 followers View post →

Pablo Corral MD

@drpablocorral · X

@PabloRichly @DLBHATTMD REDUCE-IT se publicó en 2019 https://t.co/FYwrgwr4DZ STRENGTH se detuvo precozmente por futilidad y se publicó en 2020 https://t.co/vP1XoA8o76 Lo que se presentó hoy y está publicado simultáneamente es un subanalisis del STRENGTH https://t.co/jfPJlg9bGv Esta todo publicado

May 16, 2021 · 1 like · 11,209 followers View post →

World Stroke Academy

@WorldStrokeEd · X

#WeekendLecture #SecondaryPrevention Others: Icosapent Ethyl https://t.co/cEMEiEBSFh Riva+aspirin in #ICAD https://t.co/PsOI1wr2f3 GLP-1: https://t.co/vN5c9yFJ8y We have seen a good number of studies, completed or ongoing that will give us + tools for 2ry prevention Thank you!

May 16, 2021 · 5 likes · 1 share · 14,341 followers View post →

Dr. med. Levin Kaan B.

@kaan_levin · X

Yararlı olabilecek diğer kaynaklar https://t.co/gH0476Pb8n https://t.co/SKAfvhcTds https://t.co/1OTlGqlKse

Apr 26, 2021 · 3 likes · 11,789 followers View post →

Nutrition for Sport & Performance Niagara College

@NC_SportNutri · X

RT @NanciGuestRDPhD: @Nutradvance @ScepticalDoctor @The_Nutrivore @SFZoe014 @nick_krontiris @uoftmedicine The thread was a Q - do we have e…

Apr 11, 2021 · 2 shares · 66 followers View post →

Nanci Guest PhD, RD, CSCS

@NanciGuestRDPhD · X

RT @NanciGuestRDPhD: @Nutradvance @ScepticalDoctor @The_Nutrivore @SFZoe014 @nick_krontiris @uoftmedicine The thread was a Q - do we have e…

Apr 11, 2021 · 2 shares · 10,509 followers View post →

Nanci Guest PhD, RD, CSCS

@NanciGuestRDPhD · X

RT @NanciGuestRDPhD: @KCKlatt @MrDiefenbach @SFZoe014 @The_Nutrivore @nick_krontiris @kevinnbass @ProfWhelan I disagree. O3I not a measure…

Apr 11, 2021 · 1 share · 10,509 followers View post →

pinacol

@pinacol · X

イコサペント酸エチルでの出血リスク増加は知っていたけど、心房細動や心房粗動による入院リスクが上がるのは知らなんだ。 https://t.co/pct4cato6q

Jan 10, 2021 · 3 likes · 1 share · 1,611 followers View post →

SWDK

@sA0mJBMAA4snqUf · X

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia | NEJM https://t.co/8O8DL7cccH

Jan 4, 2021 · 18 followers View post →

JoeCannonMS

@JoeCannonMS · X

@Zeypir @foundmyfitness Here is one study. In this study 4g was used. https://t.co/26OSg6s2Eh

Dec 14, 2020 · 504 followers View post →

henrik Bugge

@henrikBugge · X

RT @davidludwigmd: @michaelgoran @DoctorTro Yes, significant reduction in CVD. But a relatively modest effect on trigs compared to carbohyd…

Nov 2, 2020 · 1 share · 113 followers View post →

Chandana Shekar

@cshekarMD · X

Aug 29, 2020 · 16 likes · 1 share · 654 followers View post →

Dr. David Ludwig

@davidludwigmd · X

@michaelgoran @DoctorTro Yes, significant reduction in CVD. But a relatively modest effect on trigs compared to carbohydrate restriction (40 mg/dL here): https://t.co/HwrJmQff8s

Aug 4, 2020 · 4 likes · 1 share · 43,414 followers View post →

Dr. David Ludwig

@davidludwigmd · X

@AgnesAyton @DoctorTro Yes, significant reduction in CVD. But relatively modest effect on trigs compared to carbohydrate restriction https://t.co/HwrJmQff8s

Aug 4, 2020 · 1 like · 43,414 followers View post →

Alexander Bartelt

@BarteltLab · X

@davidludwigmd @DoctorTro Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia https://t.co/mHUPr4RcPl

Aug 4, 2020 · 2 likes · 9,024 followers View post →

Consuelo Guevara Ihl

@ConsuGuevara · X

RT @DiscoStew66: “Patients with elevated triglyceride levels are at increased risk for ischemic events. Icosapent ethyl....lowers triglycer…

Jul 28, 2020 · 1 share · 73 followers View post →

DiscoStew

@DiscoStew66 · X

“Patients with elevated triglyceride levels are at increased risk for ischemic events. Icosapent ethyl....lowers triglyceride levels,” If only there was a diet that lowered triglyceride levels

Jul 28, 2020 · 5 likes · 1 share · 10,589 followers View post →

John Osborne, MD, PhD, FACC, FNLA

@SOTHCardiology · X