A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy for female sexual dysfunction in postmenopausal women.

Channa N Jayasena, Fatima M Alkaabi, Curtis S Liebers, Thomas Handley, Stephen Franks, Waljit S Dhillo

March 2019

Synopsis of Social media discussions

The overall discussions are characterized by moderate curiosity, with some posts pointing out the limited evidence linking testosterone to sexual function, using language like 'little evidence' or 'not enough information.' Others briefly acknowledge potential benefits, but the tone remains cautious, reflecting a neutral or mildly interested stance without deep debate or strong opinions.

A
Agreement
 Neither agree nor disagree

The discussions show mixed reactions, with some posts acknowledging limited evidence and others noting potential benefits, indicating neither strong agreement nor disagreement overall.

I
Interest
 Moderate level of interest

Most posts show moderate interest; some mention the review's importance, but others seem tentative or curious without deep engagement.

E
Engagement
 Moderate level of engagement

Posts often reference specific points like the safety concerns or the evidence basis, demonstrating some level of thought and engagement with the topic.

I
Impact
 Neutral impact

The discussions suggest cautious recognition of the review’s relevance, but none emphasize a transformative or highly influential impact on clinical practice.

Social Mentions

YouTube

2 Videos

Facebook

49 Posts

Twitter

8 Posts

Instagram

1 Posts

TikTok

6 Posts

Blogs

1 Articles

Metrics

Video Views

7,746

Total Likes

241

Extended Reach

52,462

Social Features

67

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Assessing Testosterone Therapy for Women's Sexual Dysfunction

Assessing Testosterone Therapy for Women's Sexual Dysfunction

This review examines the efficacy and safety of testosterone therapy for postmenopausal women with sexual dysfunction, highlighting potential benefits and safety concerns based on randomized controlled trials.

Simple Hormones

August 6, 2021

6,158 views

The Role of Testosterone in Women's Health and Muscle Strength

The Role of Testosterone in Women's Health and Muscle Strength

This video emphasizes the significance of testosterone in women, exploring its impact on sexual health, mood, and overall well-being. Recent findings reveal that bioavailable testosterone is linked to muscle mass and strength, highlighting its unique role in female physiology during and beyond menopause.

Dr. Laurena Law

June 18, 2025

1,589 views

  • Helen Simpson
    @hormone_doc (Twitter)

    RT @ClinEndocr: From the archives. Little evidence to suggest a link between testo and sexual function in post menopausal women. Some evide…
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    November 18, 2019

    1

  • Clinical Endocrinology
    @ClinEndocr (Twitter)

    From the archives. Little evidence to suggest a link between testo and sexual function in post menopausal women. Some evidence testo improves sexual function. Not enough information to make strong recommendations-details here: https://t.co/EO1WLj0O72
    view full post

    November 18, 2019

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  • SystematicReviewBot
    @EvidenceRobot (Twitter)

    RT @michaelscally: A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy for fe…
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    November 12, 2019

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  • Mike
    @michaelscally (Twitter)

    A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy for female sexual dysfunction in postmenopausal women Introduction: Over half of... https://t.co/hxtAD6N6zS
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    November 12, 2019

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    1

  • SystematicReviewBot
    @EvidenceRobot (Twitter)

    RT @TurboKitty: A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy for femal…
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    November 12, 2019

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  • @TurboKitty (Twitter)

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    November 12, 2019

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  • SystematicReviewBot
    @EvidenceRobot (Twitter)

    RT @michaelscally: [OA] A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy f…
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    January 15, 2019

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  • Mike
    @michaelscally (Twitter)

    [OA] A systematic review of randomized controlled trials investigating the efficacy and safety of testosterone therapy for female sexual dysfunction in postmenopausal women. The clinical sequelae of oestrogen... https://t.co/bNK3lSz8ke
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Abstract Synopsis

  • This review examines whether testosterone therapy is effective and safe for improving sexual dysfunction in postmenopausal women, based on studies called randomized controlled trials.
  • While menopause is clearly linked to estrogen deficiency, the specific role of testosterone during this period is less understood, though some trials suggest it may help improve sexual function.
  • However, concerns remain about potential side effects, such as increased bone density and changes in cholesterol levels, and the long-term safety of testosterone therapy in these women is still uncertain.]