Nat Rev Neurosci February 2019 PMID 30546103

The neurobiological basis of narcolepsy.

Carrie E Mahoney, Andrew Cogswell, Igor J Koralnik, Thomas E Scammell

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Peak: 2 in Dec 2019

across 4 sources since Jan 2019

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171,636

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Jan 2019 – Jul 2025

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AI synopsis

What people are saying

Discussions highlight the importance of understanding norexin neurons and the autoimmune aspects of narcolepsy, with comments emphasizing how these findings could transform treatment approaches; the tone suggests curiosity and recognition of the study's relevance without deep technical analysis.

AgreementModerate agreement

Most discussions acknowledge the importance of understanding narcolepsy's neurobiological basis, indicating general agreement with the article's significance.

InterestModerate interest

Participants show curiosity, often referencing the potential for future treatments and the autoimmune aspect, reflecting moderate interest.

EngagementModerate engagement

Many posts briefly mention the key points or share enthusiasm through phrases like 'significant advances' and 'new insights,' showing active engagement.

ImpactModerate impact

The posts suggest that this research could influence future studies and treatments, demonstrating a recognition of its potential impact.

Abstract in brief

Narcolepsy is a neurological disorder primarily characterized by chronic sleepiness, caused by the loss of neurons that produce orexins (also called hypocretins), which are crucial for regulating sleep and wakefulness.
The discovery that narcolepsy results from the destruction of orexin neurons has led to significant advances in understanding the disorder, including evidence suggesting it may be an autoimmune condition where T cells attack these neurons.
These new insights into the neurobiological and immune mechanisms behind narcolepsy could lead to improved treatments in the future.]

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All mentions

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Science · Feb 21, 2024 1,214 views

yoshiyuki nishio

@nishiokov · X

RT @tmtakahas: The neurobiological basis of narcolepsy | Nature Reviews Neuroscience https://t.co/Znl1w4O5ig

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TmT

@tmtakahas · X

The neurobiological basis of narcolepsy | Nature Reviews Neuroscience https://t.co/Znl1w4O5ig

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Gastón F Rodríguez

@GastonFRodrigu1 · X

The neurobiological basis of narcolepsy https://t.co/qsR88Utvdi

Sep 4, 2020 · 1,155 followers View post →

Marcel Pérez-Morales

@marcelusker · X

The Neurobiological Basis of Narcolepsy https://t.co/xZBJlNPfOZ

Jul 2, 2020 · 956 followers View post →

Medicina del Dormir

@AMMDMexico · X

RT @SleepResearch_: The neurobiological basis of narcolepsy. https://t.co/XtG57wRVuc

Dec 19, 2019 · 1 share · 1,473 followers View post →

Sleep Research

@SleepResearch_ · X

The neurobiological basis of narcolepsy. https://t.co/XtG57wRVuc

Dec 19, 2019 · 1 like · 1 share · 7,258 followers View post →

Ariakas Enoreth

@Aenoreth · X

The neurobiological basis of narcolepsy https://t.co/xkCFn03jy6

Jan 23, 2019 · 1,008 followers View post →