J Physiol Pharmacol August 2018 PMID 30552302

Microbial patterns in patients with histamine intolerance.

M Schink, P C Konturek, E Tietz, W Dieterich, T C Pinzer, S Wirtz, M F Neurath, Y Zopf

Mentions

15
Peak: 2 in Oct 2020
across 6 sources since Feb 2020

Extended reach

61,779
potential audience

Total likes

1,035

Video views

40,163

Mentions per month

Feb 2020 – Feb 2024

Where it's discussed

  • X / Twitter5 posts
  • Facebook3 posts
  • YouTube2 videos
  • News2 articles
  • Blogs2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Participants express strong interest and engagement through phrases such as 'huge levers' and 'deranged gut flora,' indicating they understand and find relevance in the connection between gut microbiota and histamine intolerance. The tone is analytical and curious, with mentions of possible disease implications and biological mechanisms that underscore the potential significance of this research, though some discussions remain somewhat speculative about practical impacts.

AgreementModerate agreement

Most discussions acknowledge the importance of the gut microbiota and its role in histamine intolerance, with some affirming the findings about gut dysbiosis and intestinal barrier issues.

InterestHigh interest

The social discussions demonstrate high interest by highlighting the potential impact of gut microbiota on histamine-related disorders and mentioning related ideas like gut health and copper interactions.

EngagementHigh engagement

Participants actively reference the publication, linking it to broader concepts like gut health challenges and biochemical factors, showing deep engagement with the topic.

ImpactModerate impact

The talks suggest that this research could influence understanding or treatment of histamine intolerance, although direct clinical impact remains somewhat speculative at this stage.

Abstract in brief

  • The study found that patients with histamine intolerance (HIT) have specific gut microbiota changes, including higher levels of Proteobacteria and lower diversity of gut bacteria, which may indicate an imbalance or dysbiosis.
  • Although stool histamine levels were similar across groups, HIT patients showed increased stool zonulin levels, suggesting compromised intestinal barrier function.
  • Differences in bacterial families, such as lower Bifidobacteriaceae and reduced genera like Butyricimonas and Hespellia, along with elevated Roseburia, highlight the unique microbial profile associated with histamine intolerance.

Top posts

Most liked on X and Bluesky
UltimApe
@ultimape · X

@Mithreu @Grimhood @GSommerlund Yeah, histamine problems seem to be a huge challenge across the board. A curiosity: "... suggest a dysbiosis and intestinal barrier dysfunction in histamine intolerant patients, which in turn may play an important role in driving disease pathogenesis." https://t.co/VsA261Orct

Oct 13, 2020 · 5 likes · 6,451 followers View post →
UltimApe
@ultimape · X

@Mithreu @Grimhood "Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." https://t.co/dyZjVbDxwO Seems to at least be impact on each other. Similarly fascinated w/ copper ideas.

Oct 25, 2020 · 1 like · 6,451 followers View post →
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky

There are huge levers in the gut that tie all of this together more than people realize. "Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." pubmed.ncbi.nlm.nih.gov/30552302/

Nov 26, 2023 · 1 like · 3 shares View post →
UltimApe
@ultimape · X

"Histamine intolerance represents a controversially discussed disorder. Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." https://t.co/VsA261Orct

Jun 30, 2023 · 6,451 followers View post →
Lee Stevenson
@bashuser · X

Microbial Patterns in Patients With Histamine Intolerance https://t.co/s2Us9A258U

Feb 26, 2020 · 1,703 followers View post →
Diana
@PharmphoodTM · X

@PlanetEarth_HD @farid__jalali https://t.co/9b9b2s7ura https://t.co/W753GHYFQf https://t.co/zfZcdguE9L https://t.co/7E1aizSUbP https://t.co/nRicZlfItA https://t.co/U4mrjYD8lI

May 30, 2021 · 555 followers View post →

All mentions

Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky

There are huge levers in the gut that tie all of this together more than people realize. "Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." pubmed.ncbi.nlm.nih.gov/30552302/

Nov 26, 2023 · 1 like · 3 shares View post →
UltimApe
@ultimape · X

"Histamine intolerance represents a controversially discussed disorder. Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." https://t.co/VsA261Orct

Jun 30, 2023 · 6,451 followers View post →
Diana
@PharmphoodTM · X

@PlanetEarth_HD @farid__jalali https://t.co/9b9b2s7ura https://t.co/W753GHYFQf https://t.co/zfZcdguE9L https://t.co/7E1aizSUbP https://t.co/nRicZlfItA https://t.co/U4mrjYD8lI

May 30, 2021 · 555 followers View post →
UltimApe
@ultimape · X

@Mithreu @Grimhood "Besides an impaired degradation of orally supplied histamine due to diamine oxidase (DAO) deficiency, a deranged gut flora may also contribute to elevated histamine levels." https://t.co/dyZjVbDxwO Seems to at least be impact on each other. Similarly fascinated w/ copper ideas.

Oct 25, 2020 · 1 like · 6,451 followers View post →
UltimApe
@ultimape · X

@Mithreu @Grimhood @GSommerlund Yeah, histamine problems seem to be a huge challenge across the board. A curiosity: "... suggest a dysbiosis and intestinal barrier dysfunction in histamine intolerant patients, which in turn may play an important role in driving disease pathogenesis." https://t.co/VsA261Orct

Oct 13, 2020 · 5 likes · 6,451 followers View post →
Lee Stevenson
@bashuser · X

Microbial Patterns in Patients With Histamine Intolerance https://t.co/s2Us9A258U

Feb 26, 2020 · 1,703 followers View post →