Synopsis of Social media discussions
The overall discussion reflects curiosity and some back-and-forth on the scientific points, with mentions of specific mechanisms like glycolysis and lactate transport, as well as criticisms about outdated evidence, indicating moderate interest and engagement but uncertain impact. Words like 'interesting,' 'bizarre logic,' and references to scientific details demonstrate varied attitudes—from curiosity to skepticism.
Agreement
Neither agree nor disagreePosts show mixed opinions; some support the scientific discussion, while others dismiss or criticize it.
Interest
Moderate level of interestMost posts demonstrate curiosity or engagement with the topic, especially regarding brain glucose metabolism, but few show deep excitement.
Engagement
Moderate level of engagementSeveral discussions reference complex mechanisms and scientific debates, indicating moderate to high engagement.
Impact
Neutral impactWhile some posts raise questions or critique, there is limited evidence of the discourse leading to broad or transformative implications.
Social Mentions
YouTube
3 Videos
22 Posts
Blogs
2 Articles
News
4 Articles
Metrics
Video Views
362,244
Total Likes
15,476
Extended Reach
507,094
Social Features
31
Timeline: Posts about article
Top Social Media Posts
Veganella
The brain alone uses almost 5x that amount of glucose.
https://t.co/zBVtchv05R https://t.co/XTabEutJCU https://t.co/uZsVa2aPhr
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Dr. Philip Eckardt, MD
Interesting: „Curiously, the brain does not use its high capacity for oxidative metabolism during functional activation. Instead, glycolysis is preferentially upregulated more than oxygen consumption to sustain functions that include signaling,….“ https://t.co/wmpgDWhrtt
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Daniel Kane
“An important, unresolved issue in these studies is that the carbohydrate taken up in excess of oxygen during exhaustive exercise does not accumulate in brain (2)...” – G. Dienal, 2019 (1)
1. https://t.co/6TTuFCzI38
2. https://t.co/wkjUFSz5zr https://t.co/RINPKCWDtH https://t.co/oHZrpKXqAZ
view full post
Jennifer Madrigal
@laurenancona Depending on your idea of fun, here's a fun, thorough, and recent review:
https://t.co/hbIiLze89E
view full post
Veganella
@CGTCFA @tobyzapf @DrEenfeldt It does indeed. Nice misuse of the term “fallacies” btw. https://t.co/jwdilQb8iv
view full post
Posts referencing the article
Brain Glucose Metabolism and Its Role in Cognitive Function
Brain glucose is essential for ATP production, managing oxidative stress, and synthesizing neurotransmitters. The video explores how neuroactivity influences glucose metabolism, the debate around glucose and lactate roles, and implications for brain health and disorders.
January 8, 2022
218,642 views
The Crucial Role of Glucose in Brain Function and Health
Glucose is the primary fuel for brain functions such as ATP production, oxidative stress management, and neurotransmitter synthesis. Understanding glucose metabolism is vital for insights into brain health and potential treatments for neurological disorders.
May 16, 2021
142,664 views
Brain Glucose Metabolism and Its Role in Neural Function and Energy Use
Brain glucose is essential for ATP production, managing oxidative stress, and neurotransmitter synthesis. The video explores how glucose metabolism increases during brain activity, the roles of glucose and lactate, and their impact on brain health and potential treatments for disorders.
May 12, 2023
939 views
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RT @Veganella_: The brain alone uses almost 5x that amount of glucose. https://t.co/zBVtchv05R https://t.co/XTabEutJCU
view full postMarch 12, 2025
5
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BlueByrd (Vegan)
@NigelCo14798581 (Twitter)RT @Veganella_: The brain alone uses almost 5x that amount of glucose. https://t.co/zBVtchv05R https://t.co/XTabEutJCU
view full postMarch 12, 2025
5
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©anines tho™ ᕕ( ᐛ )ᕗ
@ShortnBluntTho (Twitter)RT @Veganella_: The brain alone uses almost 5x that amount of glucose. https://t.co/zBVtchv05R https://t.co/XTabEutJCU
view full postMarch 12, 2025
5
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Veganella
@Veganella_ (Twitter)The brain alone uses almost 5x that amount of glucose. https://t.co/zBVtchv05R https://t.co/XTabEutJCU https://t.co/uZsVa2aPhr
view full postMarch 12, 2025
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Veganella
@Veganella_ (Twitter)@CGTCFA @tobyzapf @DrEenfeldt It does indeed. Nice misuse of the term “fallacies” btw. https://t.co/jwdilQb8iv
view full postFebruary 13, 2025
4
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Earthling
@_earthling74 (Twitter)@KenDBerryMD For the benefit of your audience, would you be willing to provide a direct rebuttal (with references to support your stance) to the points made by this former carnivore diet eater? https://t.co/ruf8rhT8bU
view full postAugust 4, 2024
1
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Earthling
@_earthling74 (Twitter)@KenDBerryMD I bet you won’t watch this and guarantee you won’t have good rebuttals for it (or his book). https://t.co/F3y7OV6V11
view full postApril 8, 2024
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Steven Quartz PhD
@StevenQuartz (Twitter)@janellison @AmDiabetesAssn Ignoring that this is a sales pitch for a company whose key piece of evidence is from 1972!, this is bizarre logic. The brain does not need ketones and for its preferred substrate needs carbohydrate. Here's some actual contemporary science: https://t.co/8Cyft0PNav
view full postMarch 26, 2024
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Anna@ Miss-Information
@gsl_anna (Twitter)So interesting: https://t.co/5PsthQ3Ckc
view full postFebruary 13, 2024
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)@j_theriault @LFeldmanBarrett Wow, that was a ride! Very intense information. Thanx! https://t.co/wmpgDWhZj1
view full postAugust 31, 2023
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)„Review of the extensive older literature (151) revealed that the vagus nerve has β2-receptors and can transmit signals from blood to the brainstem, activate the locus coeruleus, and stimulate NE release throughout the brain..“ https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)„The lactate/pyruvate ratio would also rise if glycolytic rate outstripped pyruvate oxidation or if the MAS could not match glycolytic rate because of the competition of the MAS and TCA cycle for αKG.“ https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
1
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)Excitotoxicity: „Another component of the MAS, the aspartate–glutamate carrier (AGC1 or Aralar; FIGURE 1) that is the regulatory step in the NADH shuttle into mitochondria is required for rescue of cultured neurons from glutamate excitotoxicity (377).“ https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
1
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)„However, MAS inhibition has a huge impact on brain glucose oxidation providing strong evidence against predominant lactate uptake into brain mitochondria, followed by its oxidation.“ Wouldn’t MAS then be the primary intervention target? https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
1
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)Where lactate goes: „However, an advantage of glycolysis is fast production of ATP at subcellular sites with high ATP turnover (e.g., plasma membrane ion pumps) and lactate released to blood can be used by other organs as fuel or for gluconeogenesis.“ https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)Interesting: „Curiously, the brain does not use its high capacity for oxidative metabolism during functional activation. Instead, glycolysis is preferentially upregulated more than oxygen consumption to sustain functions that include signaling,….“ https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
7
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Dr. Philip Eckardt, MD
@MedEckardt (Twitter)„…after weaning, the level of monocarboxylic acid transporters in the brain's vasculature falls markedly, and β-hydroxybutyrate dehydrogenase activity also falls to the much lower adult levels…“ I wonder how ketosis still helps? @ChrisPalmerMD https://t.co/wmpgDWhrtt
view full postAugust 30, 2023
3
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Aled Zachary
@aled_zachary (Twitter)@CarnivoreIs @Pseudome17 @AFreshLitBeacon @OliverCramon @BrianCPT @AlexBulnes1 @BioLayne Diabetics can come off insulin on low carb? Lol, tell that to all the type 1 diabetics! Under normal dietary conditions the brain oxidises glucose. Fact, read this: https://t.co/u73pypfbkA
view full postJuly 18, 2023
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Daniel Kane
@mitokanedria (Twitter)“An important, unresolved issue in these studies is that the carbohydrate taken up in excess of oxygen during exhaustive exercise does not accumulate in brain (2)...” – G. Dienal, 2019 (1) 1. https://t.co/6TTuFCzI38 2. https://t.co/wkjUFSz5zr https://t.co/RINPKCWDtH https://t.co/oHZrpKXqAZ
view full postMay 24, 2023
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Jennifer Madrigal
@jenchemfolife (Twitter)@laurenancona Depending on your idea of fun, here's a fun, thorough, and recent review: https://t.co/hbIiLze89E
view full postAugust 26, 2022
5
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Red Pill Vegan
@RedPillVegan (Twitter)@zhusu Oh, No. Don’t bring this quack shit into the crypto space. https://t.co/LBRSl6eAXz
view full postMay 16, 2021
2
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Ansh Goel
@AnshGoel_Pro (Twitter)#Brain #Glucose #Metabolism: #Integration of #Energetics with #Function. https://t.co/ueRQirFXeS https://t.co/8oo0Oio26f
view full postFebruary 24, 2019
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Abstract Synopsis
- Brain glucose is essential for critical functions such as ATP production, managing oxidative stress, and synthesizing neurotransmitters and structural components.
- Neurotransmission increases glucose metabolism in both neurons and astrocytes, with glycolysis being preferentially upregulated during brain activation, even when oxygen is sufficient.
- The roles of glucose and lactate, as well as the process of shuttling between astrocytes and neurons during brain activity, are still debated, with implications for understanding brain energy use and potential treatments for brain disorders.]
@stinkiemonkie (Twitter)