December 2018 PMID 30566019

Myocardial Revascularization Trials.

Marc Ruel, Volkmar Falk, Michael E Farkouh, Nick Freemantle, Mario F Gaudino, David Glineur, Duke E Cameron, David P Taggart

Mentions

76
Peak: 47 in Oct 2019
across 5 sources since Dec 2018

Extended reach

375,413
potential audience

Total likes

350

Video views

7,007

Mentions per month

Dec 2018 – Nov 2022

Where it's discussed

  • X / Twitter66 posts
  • News5 articles
  • Facebook2 posts
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions prominently center around the methodologies of PCI versus CABG and the appropriate endpoints for myocardial revascularization trials. For instance, various comments question the use of all-cause mortality as a primary endpoint, highlighting a tone of critical analysis. Phrases like 'obligada lectura' and 'must read' suggest that participants find the publication crucial for professionals treating ischemic heart disease, reflecting both urgency and seriousness in addressing the trial comparisons. The tone across the discussions is scholarly yet engaged, as participants refer to specific studies and express curiosity about the implications of the findings.

AgreementModerate agreement

Most discussions show a general consensus on the importance of the findings discussed in the publication.

InterestHigh interest

Posts display a high level of curiosity, with many members actively seeking clarification or additional viewpoints.

EngagementHigh engagement

Many participants delve deeply into the study's methodology and implications, showcasing thoughtful analysis.

ImpactHigh impact

There is a strong belief that the publication could influence future clinical practices regarding cardiac revascularization.

Abstract in brief

  • The article reviews recent trials comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for left main and multivessel coronary artery disease.
  • It highlights that the perceived noninferiority of PCI may have been influenced by trial design, patient selection, and endpoint optimization that favored PCI.
  • The authors recommend cautious interpretation of current evidence and suggest improved collaborative designs for future clinical trials.

Top posts

Most liked on X and Bluesky
Patrick Myers
@pomyers · X

#EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG The list of authors is an impressive and international group of expert surgeons Main points in thread (1/9) https://t.co/p6nxZ3gRZC https://t.co/dXoQgEkjfs

Oct 7, 2019 · 34 likes · 22 shares · 5,453 followers View post →
John Mandrola, MD
@drjohnm · X

More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love the subtitle. Perhaps #BeyondThePrintedWord would be a good hashtag. https://t.co/DFDrWFU5CF

Oct 8, 2019 · 23 likes · 6 shares · 68,472 followers View post →
Nobu Kagiyama@Heart doctor
@KagiyamaNobu · X

このSCAIのAMI基準というのはUDに比べてCABGで10倍、PCIで1.8倍ほどAMIの診断を増やすということで、PCIに有利となる基準であることが報告されています。 続 https://t.co/WYfDHO622O https://t.co/xh83My9gRn

Dec 19, 2019 · 18 likes · 5 shares · 7,023 followers View post →
Gonzalo Aldamiz MD, FEBCTS
@galdamiz65 · X

Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial Revascularization Trials | Circulation https://t.co/3iH3EJcvJB

Oct 9, 2019 · 18 likes · 7 shares · 418 followers View post →
Victor Dayan
@VictorDayan1 · X

Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 8, 2019 · 11 likes · 7 shares · 6,778 followers View post →
David J. Cohen, MD, MSc
@djc795 · X

@kaulcsmc @pomyers @irbaz_hameed @drmikefarkouh 1/2- The underlying principle is the same. Without any explicit calculations, I think that myocardial revascularization trials of PCI vs. CABG tend to be carried out in populations with a high enough attributable risk to be reasonable for all-cause mortality endpoints.

Oct 28, 2022 · 7 likes · 1 share · 18,856 followers View post →

All mentions

Linda
@wordfinga · X

RT @djc795: @kaulcsmc @pomyers @irbaz_hameed @drmikefarkouh 1/2- The underlying principle is the same. Without any explicit calculations,…

Nov 5, 2022 · 1 share · 4,595 followers View post →
Linda
@wordfinga · X

RT @kaulcsmc: @djc795 @pomyers @irbaz_hameed @drmikefarkouh OK David, you have a point with screening trials. But what about my original qu…

Nov 5, 2022 · 1 share · 4,595 followers View post →
David J. Cohen, MD, MSc
@djc795 · X

@kaulcsmc @pomyers @irbaz_hameed @drmikefarkouh 1/2- The underlying principle is the same. Without any explicit calculations, I think that myocardial revascularization trials of PCI vs. CABG tend to be carried out in populations with a high enough attributable risk to be reasonable for all-cause mortality endpoints.

Oct 28, 2022 · 7 likes · 1 share · 18,856 followers View post →
Sanjay Kaul
@kaulcsmc · X

@djc795 @pomyers @irbaz_hameed @drmikefarkouh OK David, you have a point with screening trials. But what about my original question regarding myocardial revascularization trials? Care to share you viewpoint?

Oct 28, 2022 · 6 likes · 1 share · 3,248 followers View post →
Weill Cornell Medicine Surgery
@WCMSurgery · X

Should cause specific or overall mortality be used as the end point in myocardial revascularization trials? @BryceRobinsonMD and others answer this question in the most recent issue of @JAMAInternalMed https://t.co/MbuHkQFLjj 3/4

Oct 15, 2020 · 4 likes · 2,319 followers View post →
Caitlin Egan, MD
@CaitlinEgan18 · X

RT @BryceRobinsonMD: Our analysis on mortality in RCTs comparing CABG and PCI out now on @JAMAInternalMed. All cause mortality should be us…

Oct 13, 2020 · 1 share · 129 followers View post →
N. Bryce Robinson, MD
@BryceRobinsonMD · X

Our analysis on mortality in RCTs comparing CABG and PCI out now on @JAMAInternalMed. All cause mortality should be used as primary end point for myocardial revascularization trials #cabg #pci @WCM_CTSurgery https://t.co/Xx0jVQJ04p

Oct 12, 2020 · 6 likes · 1 share · 130 followers View post →
TSK
@TSK010 · X

RT @KagiyamaNobu: このSCAIのAMI基準というのはUDに比べてCABGで10倍、PCIで1.8倍ほどAMIの診断を増やすということで、PCIに有利となる基準であることが報告されています。 続 https://t.co/WYfDHO622O https:/…

Dec 20, 2019 · 5 shares · 683 followers View post →
医学界新聞
@igakukaishinbun · X

RT @KagiyamaNobu: このSCAIのAMI基準というのはUDに比べてCABGで10倍、PCIで1.8倍ほどAMIの診断を増やすということで、PCIに有利となる基準であることが報告されています。 続 https://t.co/WYfDHO622O https:/…

Dec 19, 2019 · 5 shares · 72,337 followers View post →
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X

RT @KagiyamaNobu: このSCAIのAMI基準というのはUDに比べてCABGで10倍、PCIで1.8倍ほどAMIの診断を増やすということで、PCIに有利となる基準であることが報告されています。 続 https://t.co/WYfDHO622O https:/…

Dec 19, 2019 · 5 shares · 14,694 followers View post →
Nobu Kagiyama@Heart doctor
@KagiyamaNobu · X

このSCAIのAMI基準というのはUDに比べてCABGで10倍、PCIで1.8倍ほどAMIの診断を増やすということで、PCIに有利となる基準であることが報告されています。 続 https://t.co/WYfDHO622O https://t.co/xh83My9gRn

Dec 19, 2019 · 18 likes · 5 shares · 7,023 followers View post →
kulvinder lall
@kulvinderlall · X

RT @sajannarayanan: @GreggWStone https://t.co/o0xAN3mrmG... SCAI definition does identify more ‘MI’ in CABG v PCI as compared to UDMI.. agr…

Dec 14, 2019 · 1 share · 1,837 followers View post →
J. Eulert-Grehn , MD
@EulertJ · X

@HighSTEACS Heraklit Panta Rhei : Myocardial Revascularization Trials | Circulation https://t.co/DGgcUCeVHz https://t.co/D3ScBZPpyC

Dec 12, 2019 · 1,907 followers View post →
Andrew Chapman
@chapdoc1 · X

RT @HighSTEACS: @chapdoc1 Data from #EXCEL on use of #UDMI criteria for peri procedural MI have not been publicly disclosed but this excell…

Dec 12, 2019 · 1 share · 2,224 followers View post →
Nicholas Mills
@HighSTEACS · X

@chapdoc1 Data from #EXCEL on use of #UDMI criteria for peri procedural MI have not been publicly disclosed but this excellent #WhitePaper from @CircAHA explains likely impact https://t.co/ZBZPPmxOZw https://t.co/p5fOHjuURq

Dec 12, 2019 · 1 like · 1 share · 3,104 followers View post →
Marcelo Mario Avellanal Leal
@parreshia · X

RT @Ekonsalud: Revisión de resultados en tratamiento de isquemia miocardica y el rol de la cirugía de revascularizacion Myocardial Revascul…

Oct 10, 2019 · 2 shares · 2,008 followers View post →
C Benítez P.
@Cebepoj · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 10, 2019 · 7 shares · 72 followers View post →
MHackem
@MHackem · X

RT @Ekonsalud: Revisión de resultados en tratamiento de isquemia miocardica y el rol de la cirugía de revascularizacion Myocardial Revascul…

Oct 10, 2019 · 2 shares · 8,347 followers View post →
Sergio Cánovas López
@sjcanovas · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 10, 2019 · 7 shares · 1,486 followers View post →
Economia de la Salud
@Ekonsalud · X

Revisión de resultados en tratamiento de isquemia miocardica y el rol de la cirugía de revascularizacion Myocardial Revascularization Trials | Circulation https://t.co/bYXRHH8y3X

Oct 9, 2019 · 5 likes · 2 shares · 5,041 followers View post →
Maria6547
@MariaLima6547 · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 9, 2019 · 7 shares · 921 followers View post →
R DiazdelCastillo N.
@catambuco · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 1,205 followers View post →
R DiazdelCastillo N.
@catambuco · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 9, 2019 · 7 shares · 1,205 followers View post →
Jose
@jose_lm78 · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 9, 2019 · 7 shares · 56 followers View post →
Fernando Biguria
@FernandoBiguria · X

RT @galdamiz65: Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial…

Oct 9, 2019 · 7 shares · 791 followers View post →
Gonzalo Aldamiz MD, FEBCTS
@galdamiz65 · X

Obligada lectura para todos profesionales implicados en el tratamiento de pacientes con cardiopatía isquemica. Myocardial Revascularization Trials | Circulation https://t.co/3iH3EJcvJB

Oct 9, 2019 · 18 likes · 7 shares · 418 followers View post →
Gonzalo Aldamiz MD, FEBCTS
@galdamiz65 · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 418 followers View post →
Jessica G.Y. Luc, MD, LLM, FRCSC
@JessicaLuc1 · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 5,129 followers View post →
INCC
@INCC_uy · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 961 followers View post →
Jose Albors Martin
@AlborsJose · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 487 followers View post →
Jose Cuenca Castillo
@JCuencaCastillo · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 9, 2019 · 7 shares · 1,734 followers View post →
Fernando Biguria
@FernandoBiguria · X

Worth reading and a sensible analysis of revasc trials up to now. https://t.co/4lsDN3e6EP

Oct 9, 2019 · 791 followers View post →
Carlos Rubén
@caruben89 · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 9, 2019 · 22 shares · 995 followers View post →
Santo Ricceri, MD
@SantoRicceri · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 9, 2019 · 6 shares · 322 followers View post →
Martha G
@MGMayanrn · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 8, 2019 · 6 shares · 638 followers View post →
Emiliano Rodríguez
@erodcauCCV · X

RT @VictorDayan1: Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 8, 2019 · 7 shares · 678 followers View post →
McMaster Cardiac Surgery
@MacCVSx · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 1,846 followers View post →
Victor Dayan
@VictorDayan1 · X

Beautiful summary written by most serious investigator in coronary artery revascularization. https://t.co/j6sOVOMUw8

Oct 8, 2019 · 11 likes · 7 shares · 6,778 followers View post →
Dr. Alex M. Benevides
@alxbenevides · X

Myocardial Revascularization in: #EXCELTrial conflict times #CABG @tomcnguyen @ArieBlitzMD @DRASCIOGLU @OuzounianMD @TsuyoshiKaneko1 @jenn_cy_chung @FernandoBiguria @GBisleri @dompagano @HirooTakayamaMD @miguelpinon_73 @FaisalBakaeen @LorraineC_MD https://t.co/yc8U6WfnMX

Oct 8, 2019 · 2 likes · 2,277 followers View post →
Fernando Biguria
@FernandoBiguria · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 8, 2019 · 6 shares · 791 followers View post →
J. Eulert-Grehn , MD
@EulertJ · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 8, 2019 · 6 shares · 1,907 followers View post →
Bil Kirmani
@drkirmani · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 2,003 followers View post →
J. Eulert-Grehn , MD
@EulertJ · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 1,907 followers View post →
Hadjer Djekhar
@DjekharHadjer · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 376 followers View post →
irene rilo
@irilomiranda · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 513 followers View post →
Luis Paredes
@LParedes7972 · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 8, 2019 · 6 shares · 171 followers View post →
Javier Andrés Duval
@javiduval · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 128 followers View post →
Rui Terenas Baptista
@rbaptista · X

RT @drjohnm: More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love…

Oct 8, 2019 · 6 shares · 200 followers View post →
John Mandrola, MD
@drjohnm · X

More good reading on understanding EXCEL and other revascularization trials here> In @CircAHA https://t.co/UkmHUL2W8n I love the subtitle. Perhaps #BeyondThePrintedWord would be a good hashtag. https://t.co/DFDrWFU5CF

Oct 8, 2019 · 23 likes · 6 shares · 68,472 followers View post →
Amir Sepehripour
@amirsepehripour · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 429 followers View post →
M. Rafati Navaei M.D.
@rafatinm · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 8, 2019 · 22 shares · 461 followers View post →
Fahd Makhdom فهد مخدوم
@FMakhdom · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 3,456 followers View post →
Aorta guy
@DrZeigler1 · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 3,743 followers View post →
bergeronium
@bergeronium · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 223 followers View post →
Emiliano Rodríguez
@erodcauCCV · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 678 followers View post →
Cardiothoracic Interdisciplinary Research Network
@CIRNetwork · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 868 followers View post →
Ravi Vazirani, MD
@DrRaviVazirani · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 1,900 followers View post →
Tamara Forrestal
@tamaranihici · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 1,081 followers View post →
Ron Figura
@RonFigura · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 652 followers View post →
Edouard L. Fu
@FuEdouard · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 1,050 followers View post →
Jessica G.Y. Luc, MD, LLM, FRCSC
@JessicaLuc1 · X

RT @pomyers: #EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG…

Oct 7, 2019 · 22 shares · 5,129 followers View post →
Patrick Myers
@pomyers · X

#EXCEL An interesting opinion published in 12.2018 (last year!), suggesting how PCI vs. CABG trials may be gamed against CABG The list of authors is an impressive and international group of expert surgeons Main points in thread (1/9) https://t.co/p6nxZ3gRZC https://t.co/dXoQgEkjfs

Oct 7, 2019 · 34 likes · 22 shares · 5,453 followers View post →
CNCFCardio
@CNCFCardio · X

RT @CircIntv: Myocardial Revascularization Trials. Working collaboratively to define the best treatment strategy for CAD patients https://t…

Jan 26, 2019 · 10 shares · 5,287 followers View post →
Circulation 日本版
@Circulation_nih · X

RT @CircAHA: #WhitePaper: Myocardial Revascularization trials: Beyond the printed word https://t.co/56nlajrQlI https://t.co/VoyOWu40i2

Jan 1, 2019 · 10 shares · 345 followers View post →
Seigo Izumo
@SeigoIzumo · X

RT @CircAHA: #WhitePaper: Myocardial Revascularization trials: Beyond the printed word https://t.co/56nlajrQlI https://t.co/VoyOWu40i2

Dec 31, 2018 · 10 shares · 3,965 followers View post →
AHA Science
@AHAScience · X

RT @CircAHA: #WhitePaper: Myocardial Revascularization trials: Beyond the printed word https://t.co/56nlajrQlI https://t.co/VoyOWu40i2

Dec 31, 2018 · 10 shares · 73,610 followers View post →