December 2018 PMID 30574122

Sirtuins and Insulin Resistance.

Shuang Zhou, Xiaoqiang Tang, Hou-Zao Chen

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Mentions

Peak: 1 in Feb 2019

across 3 sources since Feb 2019

Extended reach

4,442

potential audience

Total likes

Video views

3,005

Mentions per month

Feb 2019 – Jan 2023

Where it's discussed

X / Twitter2 posts
YouTube2 videos
News1 articles

AI synopsis

What people are saying

The overall tone suggests moderate agreement and interest, with discussions referencing how SIRT1 relates to various metabolic diseases and noting the links between Sirtuins and insulin resistance. Words like 'relationship,' 'important regulators,' and 'disease connections' reflect a recognition of scientific relevance, yet the comments are somewhat surface-level, indicating a general but cautious appreciation of the research's potential impact.

AgreementModerate agreement

Most discussions acknowledge the importance of Sirtuins, especially SIRT1, in regulating metabolic diseases, reflecting general agreement with the publication's focus.

InterestModerate interest

Participants show moderate interest in the topic, mentioning the roles of Sirtuins in insulin resistance and disease mechanisms but not delving deeply into specific details.

EngagementModerate engagement

Comments include brief summaries and mentions of the relationship between Sirtuins and health conditions, indicating some engagement but limited in-depth analysis.

ImpactModerate impact

The discussions highlight a recognition of the potential significance of Sirtuins in metabolic health, suggesting a modest perceived impact on understanding or treating diseases.

Abstract in brief

The mammalian Sirtuins, especially SIRT1 and SIRT6, are important regulators of metabolism and are linked to diseases like obesity, insulin resistance, T2DM, and cardiovascular issues.
While much is known about SIRT1 and SIRT6, the functions of other Sirtuins are still not well understood, though recent research suggests they also influence inflammation, energy metabolism, and mitochondrial health.
The review covers recent findings on how Sirtuins affect key processes involved in insulin resistance, such as inflammation and mitochondrial dysfunction, and emphasizes the need for further research to fill existing knowledge gaps.]

Read the full abstract

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Mitochondriac Dog

@PedantDog · X

2. Lays out the relationship of all the metabolic diseases to SIRT1: https://t.co/xVvGDi9F9B

Oct 18, 2020 · 1 like · 1,354 followers View post →

@tang_xiaoqiang · X

Sirtuins and Insulin Resistance https://t.co/qW1Z08AN4t

Feb 24, 2019 · 2 likes · 74 followers View post →

Metainflamacion Reprogramacion Metabolica Diabetes Obesidad ...

News

doi: 10.3389/fendo.2018.00748 102. Bele S, Girada SB, Ray A, Gupta A, Oruganti S, Babu PP, et al. Ms-275, a 84. Vana Dyke MW. Lysine Deacetylase (KDAC) ...

Dec 13, 2025 View →