January 2019 PMID 30627029

Gadolinium Deposition in the Brain: Current Updates.

Jin Woo Choi, Won-Jin Moon

Mentions

18
Peak: 13 in Jun 2019
across 2 sources since Jun 2019

Extended reach

52,298
potential audience

Total likes

23

Video views

50

Mentions per month

Jun 2019 – Apr 2022

Where it's discussed

  • X / Twitter17 posts
  • YouTube1 videos

AI synopsis

What people are saying

The collective discussions highlight significant concern about gadolinium deposits in the brain, with references to specific research findings such as T1 hyperintensities in brain regions like the dentate nucleus and globus pallidus. The tone is serious and analytical, emphasizing the potential clinical and public health implications, which justifies high interest and impact scores.

AgreementModerate agreement

Most discussions acknowledge the concerns raised by the publication, showing support for its findings about gadolinium retention and potential risks.

InterestHigh interest

Posts display high interest, referencing specific brain regions affected and discussing new research and clinical implications.

EngagementHigh engagement

Several discussions delve into detailed analysis, referencing studies and technical aspects, indicating deep engagement.

ImpactHigh impact

The discussions suggest the research could influence medical practices and public health policies, reflecting high potential impact.

Abstract in brief

  • Gadolinium-based contrast agents (GBCAs) are widely used in MRI scans and considered safe at recommended doses, but concerns have risen after evidence showed they can remain in the body and deposit in tissues, including the brain.
  • Brain deposition of gadolinium is mainly associated with linear GBCAs, which have a specific chemical structure that makes them more likely to stay in the brain compared to other types.
  • The review discusses current findings on gadolinium accumulation in the brain and explores potential clinical implications, emphasizing the need for caution and further research.]

Top posts

Most liked on X and Bluesky
B. Wagner, M.D.
@Wagner_Nephro · X

#Gadolinium ☠️ has been detected in:

Jun 20, 2019 · 8 likes · 3 shares · 3,331 followers View post →
tune
@keisuke4713 · X

脳内Gd沈着 https://t.co/unjbNCrwhG 脳内GBCA沈着:殆どが特定キレート構造に関連 Gd沈着は錐体外路系の機能障害に関連? 後年のパーキンソニズムに関連? 腎疾患や小児でより注意 歯状核の高信号域:多発性硬化症に関連 頻回MRIの結果の可能性 淡蒼球の高信号域:肝障害に関連 https://t.co/Hx8tDUdzTW https://t.co/rB9nWCRXHo

Apr 21, 2022 · 3 likes · 3 shares · 3,748 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“[T]he T1 hyperintensities are not limited to these two structures but appear to involve other areas of the brain, including the pulvinar of the thalamus, the precentral and postcentral cortex, the calcarine cortex,” #gadolinium #neurology

Jun 20, 2019 · 2 likes · 1 share · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“McDonald et al. ... confirmed the causal relationship between T1 hyperintensities and gadolinium exposure by [correlating] with the concentration of gadolinium in the brain tissue, measured by inductively coupled plasma mass spectrometry (ICP-MS),”

Jun 20, 2019 · 2 likes · 1 share · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

Gadolinium➡️hyperintensities: dentate nucleus (100%) globus pallidus (100%) substantia nigra (100%) posterior thalamus (92%) red nucleus (77%) colliculi (77%) superior cerebellar peduncle (54%), caudate nucleus (31%) whole thalamus (23%) putamen (15%) https://t.co/ITCXnKFAYH

Jun 20, 2019 · 2 likes · 3,331 followers View post →
Dmitrij
@kurilod · X

@HrsQuiet I was amazed reading all research on that before my MRI. Probably postponing now. Taking zinc supplements everyday which may backfire due to transmetalation https://t.co/bE7yT7vCjp

Jun 25, 2019 · 2 likes · 1,730 followers View post →

All mentions

Apple
@Apple89570468 · X

RT @keisuke4713: 脳内Gd沈着 https://t.co/unjbNCrwhG 脳内GBCA沈着:殆どが特定キレート構造に関連 Gd沈着は錐体外路系の機能障害に関連? 後年のパーキンソニズムに関連? 腎疾患や小児でより注意 歯状核の高信号域:多発性硬化症に関…

Apr 22, 2022 · 3 shares · 48 followers View post →
tune
@keisuke4713 · X

脳内Gd沈着 https://t.co/unjbNCrwhG 脳内GBCA沈着:殆どが特定キレート構造に関連 Gd沈着は錐体外路系の機能障害に関連? 後年のパーキンソニズムに関連? 腎疾患や小児でより注意 歯状核の高信号域:多発性硬化症に関連 頻回MRIの結果の可能性 淡蒼球の高信号域:肝障害に関連 https://t.co/Hx8tDUdzTW https://t.co/rB9nWCRXHo

Apr 21, 2022 · 3 likes · 3 shares · 3,748 followers View post →
barış bora Peker
@sennasthunder · X

RT @Wagner_Nephro: #Gadolinium ☠️ has been detected in:

Nov 19, 2019 · 3 shares · 503 followers View post →
Gadolinium Toxic
@GadoliniumToxic · X

RT @Wagner_Nephro: #Gadolinium ☠️ has been detected in:

Nov 19, 2019 · 3 shares · 491 followers View post →
Dmitrij
@kurilod · X

@HrsQuiet I was amazed reading all research on that before my MRI. Probably postponing now. Taking zinc supplements everyday which may backfire due to transmetalation https://t.co/bE7yT7vCjp

Jun 25, 2019 · 2 likes · 1,730 followers View post →
Mary Gerdt Parler:Alvarita1
@marygerdt · X

RT @Wagner_Nephro: #Gadolinium ☠️ has been detected in:

Jun 20, 2019 · 3 shares · 6,011 followers View post →
Mary Gerdt Parler:Alvarita1
@marygerdt · X

RT @Wagner_Nephro: “[T]he T1 hyperintensities are not limited to these two structures but appear to involve other areas of the brain, inclu…

Jun 20, 2019 · 1 share · 6,011 followers View post →
Mary Gerdt Parler:Alvarita1
@marygerdt · X

RT @Wagner_Nephro: “Thus, radiologists and clinicians are feeling pressured to understand the significance of [gadolinium-based contrast ag…

Jun 20, 2019 · 1 share · 6,011 followers View post →
Doesnt Sleep
@Dsntslp · X

RT @Wagner_Nephro: “McDonald et al. ... confirmed the causal relationship between T1 hyperintensities and gadolinium exposure by [correlati…

Jun 20, 2019 · 1 share · 1,000 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

#Gadolinium ☠️ has been detected in:

Jun 20, 2019 · 8 likes · 3 shares · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“McDonald et al. ... confirmed the causal relationship between T1 hyperintensities and gadolinium exposure by [correlating] with the concentration of gadolinium in the brain tissue, measured by inductively coupled plasma mass spectrometry (ICP-MS),”

Jun 20, 2019 · 2 likes · 1 share · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

These authors cite a study where thirteen patients each had over 35 exposures to gadolinium-based contrast agents. #gadolinium #radiology ☢️ #publichealth #toxicology #nephrology #neurology

Jun 20, 2019 · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

Gadolinium➡️hyperintensities: dentate nucleus (100%) globus pallidus (100%) substantia nigra (100%) posterior thalamus (92%) red nucleus (77%) colliculi (77%) superior cerebellar peduncle (54%), caudate nucleus (31%) whole thalamus (23%) putamen (15%) https://t.co/ITCXnKFAYH

Jun 20, 2019 · 2 likes · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“[T]he T1 hyperintensities are not limited to these two structures but appear to involve other areas of the brain, including the pulvinar of the thalamus, the precentral and postcentral cortex, the calcarine cortex,” #gadolinium #neurology

Jun 20, 2019 · 2 likes · 1 share · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“Early reports on gadolinium deposition in the brain mainly focused on signal changes in the dentate nucleus and globus pallidus on MRI,” #gadolinium #radiology ☢️ #publichealth #toxicology #neurology

Jun 20, 2019 · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

“Thus, radiologists and clinicians are feeling pressured to understand the significance of [gadolinium-based contrast agent] accumulation in the brain as the recent evidence suggests.” #gadolinium #radiology ☢️ #neurology

Jun 20, 2019 · 1 like · 1 share · 3,331 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

Despite the suspension of many classes of gadolinium-based contrast agents, and public warnings about #gadolinium ☠️ brain retention, “public concerns continue to increase,” https://t.co/ITCXnKFAYH

Jun 20, 2019 · 1 like · 3,331 followers View post →