The relationship between autophagy and the immune system and its applications for tumor immunotherapy.

Guan-Min Jiang, Yuan Tan, Hao Wang, Liang Peng, Hong-Tao Chen, Xiao-Jun Meng, Ling-Ling Li, Yan Liu, Wen-Fang Li, Hong Shan

January 2019 Mol Cancer

Synopsis of Social media discussions

The overall discussions show a high level of interest, with posts referencing multiple reviews and emphasizing the immune system's modulation by autophagy. The tone varies from supportive to cautiously critical, with some posts questioning biases and others noting the therapeutic potential, reflecting active engagement and recognition of the article's significance.

A
Agreement
 Moderate agreement

Most comments recognize the significance of autophagy's role in cancer and immune responses, showing moderate support for the publication's findings.

I
Interest
 High level of interest

Discussions highlight growing curiosity, with mentions of multiple reviews and interest in therapeutic applications, indicating high engagement.

E
Engagement
 Moderate level of engagement

Comments include sharing of links, references to studies, and critical remarks, suggesting active involvement.

I
Impact
 Moderate level of impact

Many perceive the research as relevant and potentially influential, especially given the mention of new treatment avenues and research interest.

Social Mentions

YouTube

4 Videos

Twitter

11 Posts

News

29 Articles

Metrics

Video Views

84,059

Total Likes

1,770

Extended Reach

2,390,991

Social Features

44

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Understanding Autophagy: Cellular Recycling and Its Role in Immunity

Understanding Autophagy: Cellular Recycling and Its Role in Immunity

Autophagy is a cellular process that degrades and recycles components. It plays a vital role in regulating immune responses and tumor development. Modulating autophagy can enhance tumor immunotherapy by improving immune cell functions and overcoming resistance.

Kimmy Y

September 13, 2019

58,418 views

Autophagy's Role in Immune Regulation and Cancer Therapy

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Autophagy significantly influences immune responses by modulating immune cell functions and cytokine production. Fasting can boost immunity and regulate autophagy, offering potential benefits for tumor immunotherapy and health.

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January 7, 2021

25,280 views

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Understanding AMPK and mTOR in Cellular Health and Metabolism

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August 3, 2025

306 views

Autophagy's Role in Strengthening Your Immune System Explained

Autophagy's Role in Strengthening Your Immune System Explained

Autophagy builds a strong immune system by mediating pathogen clearance and supporting immune cell functions. It plays a key role in innate and adaptive immunity, aiding in thymic selection, antigen presentation, and cytokine regulation.

Handgun Safety Academy

March 18, 2020

56 views

  • Dra. Inflamación
    @SaraCabreraN (Twitter)

    RT @IberianCitizen: De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las res…
    view full post

    August 14, 2022

    2

  • MarHumano
    @MarHumano (Twitter)

    RT @IberianCitizen: De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las res…
    view full post

    August 14, 2022

    2

  • IberianCitizen
    @IberianCitizen (Twitter)

    De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las respuestas inflamatorias e inmunitarias controlando el desarrollo tumoral. Los macrófagos es solo una de ellas https://t.co/58CYbDla3r https://t.co/ibK84d2pYC
    view full post

    August 14, 2022

    10

    2


  • @OhMalG (Twitter)

    @ultimape @Mangan150 @jasonmpeirce @naval https://t.co/hzFZLFsRKe https://t.co/F52W37bwXr
    view full post

    February 24, 2022

  • data
    @browser_data (Twitter)

    @TimbrookLynn @RWMaloneMD Some sources (autophagy/immune system): 1. https://t.co/zS8rayecLV 2. https://t.co/k9AQ0d8DZc 3. https://t.co/q13Rrw2r0q 4. https://t.co/aSV2CcDMyP 5. https://t.co/SvZnufeWum
    view full post

    December 2, 2021

  • Kinini Chrizz
    @_kinchris_ (Twitter)

    RT @amerix: @ManFelo74 Autophagy modulates immune system mainly T and B lymphocytes, But I guess humans will love to stick to excuses and…
    view full post

    September 5, 2020

    1

  • Eric
    @amerix (Twitter)

    @ManFelo74 Autophagy modulates immune system mainly T and B lymphocytes, But I guess humans will love to stick to excuses and biases because unlearning ruffles their discomfort. https://t.co/tpuEraygrD
    view full post

    September 5, 2020

    7

    1

  • Siwen Hu-Lieskovan
    @SiwenONC (Twitter)

    RT @jitcancer: Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews
    view full post

    April 1, 2020

    2

  • markcl208041
    @markcl208041 (Twitter)

    RT @jitcancer: Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews
    view full post

    April 1, 2020

    2

  • Journal for ImmunoTherapy of Cancer
    @jitcancer (Twitter)

    Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews
    view full post

    April 1, 2020

    2

    2

  • Victoria Hendry
    @HendryVictoria (Twitter)

    The relationship between autophagy and the immune system and its applications for tumor immunotherapy. https://t.co/grGfmwFSFF ⁦@alanlparker⁩
    view full post

    January 28, 2019

Abstract Synopsis

  • Autophagy is a cellular process regulated by core genes that can either promote or suppress tumor development depending on the context, and it also plays a key role in controlling immune responses.
  • Recent research suggests that modulating autophagy can enhance tumor immunotherapy by improving immune cell functions and antigen presentation, but it may also allow tumors to escape immune detection, leading to resistance.
  • Targeting autophagy with either inducers or inhibitors, in combination with immunotherapy, shows promise in fighting cancer by boosting immune responses and overcoming tumor resistance mechanisms.