Mol Cancer January 2019 PMID 30678689

The relationship between autophagy and the immune system and its applications for tumor immunotherapy.

Guan-Min Jiang, Yuan Tan, Hao Wang, Liang Peng, Hong-Tao Chen, Xiao-Jun Meng, Ling-Ling Li, Yan Liu, Wen-Fang Li, Hong Shan

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Mentions

44
Peak: 3 in Apr 2020
across 3 sources since Jan 2019

Extended reach

2,390,991
potential audience

Total likes

1,770

Video views

84,059

Mentions per month

Jan 2019 – Aug 2025

Where it's discussed

  • News29 articles
  • X / Twitter11 posts
  • YouTube4 videos

AI synopsis

What people are saying

The overall discussions show a high level of interest, with posts referencing multiple reviews and emphasizing the immune system's modulation by autophagy. The tone varies from supportive to cautiously critical, with some posts questioning biases and others noting the therapeutic potential, reflecting active engagement and recognition of the article's significance.

AgreementModerate agreement

Most comments recognize the significance of autophagy's role in cancer and immune responses, showing moderate support for the publication's findings.

InterestHigh interest

Discussions highlight growing curiosity, with mentions of multiple reviews and interest in therapeutic applications, indicating high engagement.

EngagementModerate engagement

Comments include sharing of links, references to studies, and critical remarks, suggesting active involvement.

ImpactModerate impact

Many perceive the research as relevant and potentially influential, especially given the mention of new treatment avenues and research interest.

Abstract in brief

  • Autophagy is a cellular process regulated by core genes that can either promote or suppress tumor development depending on the context, and it also plays a key role in controlling immune responses.
  • Recent research suggests that modulating autophagy can enhance tumor immunotherapy by improving immune cell functions and antigen presentation, but it may also allow tumors to escape immune detection, leading to resistance.
  • Targeting autophagy with either inducers or inhibitors, in combination with immunotherapy, shows promise in fighting cancer by boosting immune responses and overcoming tumor resistance mechanisms.

Top posts

Most liked on X and Bluesky
IberianCitizen
@IberianCitizen · X

De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las respuestas inflamatorias e inmunitarias controlando el desarrollo tumoral. Los macrófagos es solo una de ellas https://t.co/58CYbDla3r https://t.co/ibK84d2pYC

Aug 14, 2022 · 10 likes · 2 shares · 12,926 followers View post →
Eric
@amerix · X

@ManFelo74 Autophagy modulates immune system mainly T and B lymphocytes, But I guess humans will love to stick to excuses and biases because unlearning ruffles their discomfort. https://t.co/tpuEraygrD

Sep 5, 2020 · 7 likes · 1 share · 2,258,484 followers View post →
Journal for ImmunoTherapy of Cancer
@jitcancer · X

Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews

Apr 1, 2020 · 2 likes · 2 shares · 9,299 followers View post →
MarHumano
@MarHumano · X

RT @IberianCitizen: De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las res…

Aug 14, 2022 · 2 shares · 22,855 followers View post →
Victoria Hendry
@HendryVictoria · X

The relationship between autophagy and the immune system and its applications for tumor immunotherapy. https://t.co/grGfmwFSFF ⁦@alanlparker⁩

Jan 28, 2019 · 1,318 followers View post →
markcl208041
@markcl208041 · X

RT @jitcancer: Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews

Apr 1, 2020 · 2 shares · 826 followers View post →

All mentions

Dra. Inflamación
@SaraCabreraN · X

RT @IberianCitizen: De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las res…

Aug 14, 2022 · 2 shares · 7 followers View post →
MarHumano
@MarHumano · X

RT @IberianCitizen: De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las res…

Aug 14, 2022 · 2 shares · 22,855 followers View post →
IberianCitizen
@IberianCitizen · X

De hecho, la activación de la autofagia puede promover o inhibir la secreción de citoquinas que ayudan a mediar las respuestas inflamatorias e inmunitarias controlando el desarrollo tumoral. Los macrófagos es solo una de ellas https://t.co/58CYbDla3r https://t.co/ibK84d2pYC

Aug 14, 2022 · 10 likes · 2 shares · 12,926 followers View post →
OhMalG
@OhMalG · X

@ultimape @Mangan150 @jasonmpeirce @naval https://t.co/hzFZLFsRKe https://t.co/F52W37bwXr

Feb 24, 2022 · 491 followers View post →
data
@browser_data · X

@TimbrookLynn @RWMaloneMD Some sources (autophagy/immune system): 1. https://t.co/zS8rayecLV 2. https://t.co/k9AQ0d8DZc 3. https://t.co/q13Rrw2r0q 4. https://t.co/aSV2CcDMyP 5. https://t.co/SvZnufeWum

Dec 2, 2021 · 158 followers View post →
Kinini Chrizz
@_kinchris_ · X

RT @amerix: @ManFelo74 Autophagy modulates immune system mainly T and B lymphocytes, But I guess humans will love to stick to excuses and…

Sep 5, 2020 · 1 share · 80 followers View post →
Eric
@amerix · X

@ManFelo74 Autophagy modulates immune system mainly T and B lymphocytes, But I guess humans will love to stick to excuses and biases because unlearning ruffles their discomfort. https://t.co/tpuEraygrD

Sep 5, 2020 · 7 likes · 1 share · 2,258,484 followers View post →
Siwen Hu-Lieskovan
@SiwenONC · X

RT @jitcancer: Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews

Apr 1, 2020 · 2 shares · 462 followers View post →
markcl208041
@markcl208041 · X

RT @jitcancer: Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews

Apr 1, 2020 · 2 shares · 826 followers View post →
Journal for ImmunoTherapy of Cancer
@jitcancer · X

Growing interest in #autophagy, #cancer & #immunotherapy. 3 reviews

Apr 1, 2020 · 2 likes · 2 shares · 9,299 followers View post →
Victoria Hendry
@HendryVictoria · X

The relationship between autophagy and the immune system and its applications for tumor immunotherapy. https://t.co/grGfmwFSFF ⁦@alanlparker⁩

Jan 28, 2019 · 1,318 followers View post →