En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación con una estrategia dirigida a los niveles séricos de lactato, NO REDUCE la MORTALIDAD por todas las causas a 28 días. JAMA 2019; doi:10.1001/jama.2019.0071 https://t.co/3FUkYQUkUW
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial.
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Feb 2019 – Dec 2024Where it's discussed
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X / Twitter82 posts
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Facebook18 posts
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News15 articles
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Blogs14 articles
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YouTube3 videos
AI synopsis
What people are saying
Several discussions highlight the comparison between capillary refill time and lactate levels, such as remarks like 'it is my favorite study of recent years' or mentioning how 'this study provides reassurance amidst the clinical picture of septic shock.' These choices of words and the enthusiastic tone indicate a mix of admiration and cautious optimism, contributing to the overall sentiment of support while also assessing the trial's clinical relevance.
Most discussions indicate a level of support for the findings of the ANDROMEDA-SHOCK trial, though some express skepticism about its implications.
Participants show a strong interest in the trial's results and methodology, often referencing the study in relation to clinical practice.
While some posts provide detailed insights into the methods and significance, others remain more superficial.
The perceived impact is moderate; while some contributors see its relevance in clinical application, others question its significance.
Abstract in brief
- The study aimed to compare the effectiveness of resuscitation focused on peripheral perfusion versus serum lactate levels in reducing 28-day mortality for patients with septic shock.
- Conducted across 28 ICUs in 5 countries, 424 patients were randomly assigned to either a peripheral perfusion-targeted protocol or a lactate-targeted protocol during an 8-hour intervention.
- Results showed that while there was no significant difference in mortality (34.9% in the peripheral group vs. 43.4% in the lactate group), peripheral perfusion-targeted resuscitation was linked to reduced organ dysfunction within 72 hours.
Top posts
Most liked on X and BlueskyWhat about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022 https://t.co/LMyfobiG9P
#CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/2KI9LObTcS. Access all late-breakers: https://t.co/CMKIVEG6BN
Episode 46! We talk about tPA in CVA (TIMELESS) published by @NEJM and then our old article is ANDROMEDA-SHOCK (cap refill vs lactate) published @JAMA_current TIMELESS: https://t.co/Oy8BOwBjsL ANDROMEDA:https://t.co/VAjT6UBJpu On your fav podcast app: https://t.co/qPyhTM3p2C
Una de las estrellas de hoy en #CCC48. @SCCM 2 estrategias para guiar la resucitación temprana en choque séptico. Llenado capilar vs Aclaramiento lactato. Diferencia −8.5% [95% CI, −18.2% a 1.2%] https://t.co/4ZslIozUBN https://t.co/Ig0rNs5Xtc
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/JxmsuqD3BQ #IFAD2020
All mentions
Key Updates on Sepsis Management in 2021 Guidelines
Sepsis is a critical syndrome that requires prompt recognition and treatment. In this episode, Carol and Fabricio discuss the essential updates from the latest 2021 guidelines, focusing on identification tools, lactate…
Key Updates on Sepsis Management and Resuscitation Strategies
This video discusses crucial updates on sepsis, focusing on the latest 2021 guidelines. Topics include identification tools, the role of lactate, fluid therapy based on fluid responsiveness, and the use of vasoactive…
Impact of Sleep and Norepinephrine on Health Outcomes
This video reviews critical findings on poor sleep as a risk factor for type 2 diabetes and emphasizes the role of early low-dose norepinephrine in septic shock management. Recent studies indicate that effective sleep…
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@Miguel99RD @OrlandoRPN https://t.co/IdUrStnDj1 allí está la publicación
RT @IcuCast: Episode 46! We talk about tPA in CVA (TIMELESS) published by @NEJM and then our old article is ANDROMEDA-SHOCK (cap refill vs…
RT @IcuCast: Episode 46! We talk about tPA in CVA (TIMELESS) published by @NEJM and then our old article is ANDROMEDA-SHOCK (cap refill vs…
RT @IcuCast: Episode 46! We talk about tPA in CVA (TIMELESS) published by @NEJM and then our old article is ANDROMEDA-SHOCK (cap refill vs…
Episode 46! We talk about tPA in CVA (TIMELESS) published by @NEJM and then our old article is ANDROMEDA-SHOCK (cap refill vs lactate) published @JAMA_current TIMELESS: https://t.co/Oy8BOwBjsL ANDROMEDA:https://t.co/VAjT6UBJpu On your fav podcast app: https://t.co/qPyhTM3p2C
Journal Club de Julio Revisaremos el ANDROMEDA SHOCK Trial y los análisis secundarios realizados con diferente abordaje metodológico y cómo esto influye en la interpretación de los resultados, mismos que repercuten en nuestro que hacer clínico. https://t.co/mwJZQ5INRU https://t.co/4PVfzZ05oV
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
RT @avkwong: What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022…
What about the simple capillary refill time - ping @AndromedaShock study It is my favourite study of recent years. #LIVES2022 https://t.co/LMyfobiG9P
A crucial point - most of our macrocirculatory parameters fail to assess the microcirculation. S(c)VO2 utility is limited by this 10.1001/jama.2019.0071 #CCSSA2022
The ANDROMEDA-SHOCK trial, published in JAMA 2019, looked at comparing lactate to capillary refill time as a resuscitative end point and showed no difference in 28day mortality. 10.1001/jama.2019.0071
Önemli bir nokta da “istatistiken anlamlı - istatistiken anlamlı değil” gibi bir ikileme gidiliyor olması (detay: https://t.co/7scfrPlRkm). Çünkü 0.06 p değeri elde edilmiş bir çalışma başarısız olarak gösterilebiliyor (https://t.co/8ZP4Aul5LN).
RT @DiegoEscarraman: @fidel52695580 https://t.co/TMksn2EKTZ Acá toda la información necesaria doc.
RT @DiegoEscarraman: @fidel52695580 https://t.co/TMksn2EKTZ Acá toda la información necesaria doc.
@fidel52695580 https://t.co/TMksn2EKTZ Acá toda la información necesaria doc.
最近は循環生理を勉強し直している所でありまして、苦手なPV loopと格闘中です。 ただ、重症心不全や術前重症例の術後などでは、所謂「循環」であるマクロ循環だけでなく、ミクロ循環や細胞内代謝が重要やなと思ってる次第です。physical assessmentの重要性を改めて認識。 https://t.co/ijCb537Htx
RT @avkwong: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Pat…
RT @avkwong: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Pat…
RT @avkwong: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Pat…
RT @avkwong: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Pat…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/JxmsuqD3BQ #IFAD2020
El estudio ANDROMEDA SHOCK. Al existir tantas limitantes en nuestro medio este estudio dio tranquilidad en medio del cuadro clínico por Shock septico.
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock The ANDROMEDA-SHOCK Randomized Clinical Trial https://t.co/pkrl2MHAR8
3/n Um exemplo foi o estudo ANDROMEDA-SHOCK trial Hernández et al sobre o efeito da perfusão periférica no resultado final da ressuscitação volêmica de pacientes em choque circulatório. JAMA. 2019 doi:10.1001/jama.2019.0071
The ANDROMEDA-SHOCK Randomized Clinical Trial Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/frR0pZ1J3D https://t.co/dzvHRmJMdq
Journal club : Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/1QD60nhHcG https://t.co/3h4suXd38h
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients with Septic Shock: A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial #AJRCCM #IntensiveCare https://t.co/NkwREGIEOA
@glennguru1 @JAMA_current 10/ Bibliografía:
RT @galabozzano: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among…
Choque Séptico #Urgencias #EmergencyMedicine doi:10.1001/jama.2019.0071 https://t.co/M0IFsxaZC5
RT @VirginiaHdezGea: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality A…
RT @VirginiaHdezGea: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality A…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/ThO6Y6Pe4v
RT @FVLCali: #InvestigacionFVL invita a leer artículo 'Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum La…
RT @FVLCali: #InvestigacionFVL invita a leer artículo 'Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum La…
#InvestigacionFVL invita a leer artículo 'Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality among Patients with Septic Shock'. Revista: JAMA Autor: Dr. Gustavo A. Ospina T. https://t.co/efvkVw6ZFG https://t.co/x7dxTNLkmZ
RT @JacobMillerACNP: @jasumback on ANDROMEDA-SHOCK: Perfusion (cap refill)-guided resuscitation no worse than lactate-guided. See also: "W…
@jasumback on ANDROMEDA-SHOCK: Perfusion (cap refill)-guided resuscitation no worse than lactate-guided. See also: "When all else fails, assess your patient" https://t.co/N8cV70A6gm #CCTMC19 @CCTMC1
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. #Critical Care Medicine #JAMA https://t.co/PlHVE6uoA1
RT @JAMA_current: The #ISICEM19 exhibit hall is open. Stop by booth D4 to get a copy of "Effect of a Resuscitation Strategy Targeting Perip…
The #ISICEM19 exhibit hall is open. Stop by booth D4 to get a copy of "Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial"
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/3TUX2lcqTV
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. https://t.co/GaPwhB23hC
RT @Fsphc1: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Pati…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. https://t.co/ZZTPstuev9
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial | Read by QxMD https://t.co/h4BMUnGGNQ
Very interesting!! Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/mbcD0RQbkO
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/WIBLxq9OnM
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/wrBrc7fYYF
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/qgOi0lkFqO
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
RT @AmbrizMau: En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación…
En choque séptico, una estrategia de resucitación dirigida a la normalización del tiempo de llenado capilar, en comparación con una estrategia dirigida a los niveles séricos de lactato, NO REDUCE la MORTALIDAD por todas las causas a 28 días. JAMA 2019; doi:10.1001/jama.2019.0071 https://t.co/3FUkYQUkUW
RT @maite_adell: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/yvEXDRg0TL
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial https://t.co/rvZ9SgoZpB
Lactate vs cap refill Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With sepsis: | Critical Care Medicine | JAMA | JAMA Network https://t.co/XTy2cJvIDn
RT @quinonezmd: Una de las estrellas de hoy en #CCC48. @SCCM 2 estrategias para guiar la resucitación temprana en choque séptico. Llenado…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/14p4Xp5qkT
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/80b1Wp5Q0N
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/m1UwZdjDoV
Una de las estrellas de hoy en #CCC48. @SCCM 2 estrategias para guiar la resucitación temprana en choque séptico. Llenado capilar vs Aclaramiento lactato. Diferencia −8.5% [95% CI, −18.2% a 1.2%] https://t.co/4ZslIozUBN https://t.co/Ig0rNs5Xtc
RT @SCCM: #CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status v…
Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. | Critical Care Medicine | JAMA | JAMA Network https://t.co/auh4C043G3
RT @SCCM: #CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status v…
RT @SCCM: #CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status v…
RT @SCCM: #CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status v…
RT @SCCM: #CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status v…
#CCC48 Access the late-breaking @JAMA_current article: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock https://t.co/2KI9LObTcS. Access all late-breakers: https://t.co/CMKIVEG6BN