The collective discussions reflect a clear consensus that the systematic review indicates glucagon's lack of benefit and increased risks, with posts emphasizing its clinical relevance and questioning routine use. Words like 'no benefit' and 'significant increase in adverse events' highlight dissatisfaction and concern, demonstrating both high engagement and interest with moderate perceived impact on practice changes.
AgreementModerate agreement
Most discussions agree that the review shows glucagon is ineffective and potentially harmful, with some questioning why it's still used.
InterestHigh interest
Posts demonstrate high interest, with emphasis on the importance and implications of the findings about glucagon.
EngagementHigh engagement
Many users engage deeply by referencing specific aspects of the research, such as safety concerns and clinical practices.
ImpactModerate impact
The discussions highlight the potential change in clinical guidelines or practices, indicating moderate overall impact on the medical community.
Abstract in brief
Glucagon is often used to help pass esophageal foreign bodies and food impactions, but this review found it does not significantly improve treatment success compared to placebo.
The study analyzed five research articles with over 1,100 patients and found that while glucagon did not increase the chances of relief, it was associated with more adverse events, although serious side effects were rare.
Overall, the evidence suggests glucagon might not be effective for this purpose and could increase the risk of side effects like vomiting, so its routine use for esophageal foreign bodies should be reconsidered.
This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esophageal foreign body and food impactions. https://t.co/Ic8Qy8W5vR @accpemedprn https://t.co/Ba4AF0OfpK
Feb 26, 2019 · 13 likes · 6 shares · 11,870 followersView post →
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Pharmacotherapy
@PharmacoJournal · X
https://t.co/XHeEsSFzU4 https://t.co/ljAzMGBGl8
May 16, 2019 · 9 likes · 4 shares · 11,870 followersView post →
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Marc Probst
@probstMD · X
SRMA looking at Glucagon for esophageal FB or food impaction.
TL;DR - NO BENEFIT and significant increase in adverse events.
So, why do you still give it?
For fear of having the GI fellow scold us? Or simply another example of commission bias?
https://t.co/V9DP0kYRuO https://t.co/nJjpORwfXe
Feb 26, 2019 · 7 likes · 1 share · 960 followersView post →
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Pharmacotherapy
@PharmacoJournal · X
This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esophageal foreign body and food impactions. https://t.co/KlNflFEIe4 @accpemedprn https://t.co/Hp7SvZPtL6
Mar 12, 2019 · 4 likes · 1 share · 11,870 followersView post →
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EM Drug Info Geek
@DrugInfoGeek · X
@jtrebach @matt622h I would guess similar to placebo, https://t.co/GQfB1Nw9es
Contributor Aaron Lessen MD reviews the efficacy of treatments for esophageal food impactions. While carbonation can help passage, glucagon shows no significant benefit and may cause adverse effects, suggesting…
Delve into the management of esophageal foreign body obstructions, a common emergency. We discuss symptoms, causes, treatment protocols, and the effectiveness of interventions like glucagon, highlighting real-life…
May 16, 2019 · 4 shares · 1,888 followersView post →
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Pharmacotherapy
@PharmacoJournal · X
https://t.co/XHeEsSFzU4 https://t.co/ljAzMGBGl8
May 16, 2019 · 9 likes · 4 shares · 11,870 followersView post →
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SystematicReviewBot
@EvidenceRobot · X
RT @PharmacoJournal: This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esoph…
Mar 12, 2019 · 1 share · 6,686 followersView post →
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Pharmacotherapy
@PharmacoJournal · X
This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esophageal foreign body and food impactions. https://t.co/KlNflFEIe4 @accpemedprn https://t.co/Hp7SvZPtL6
Mar 12, 2019 · 4 likes · 1 share · 11,870 followersView post →
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Matt Klein
@MKleinMD · X
RT @probstMD: SRMA looking at Glucagon for esophageal FB or food impaction.
TL;DR - NO BENEFIT and significant increase in adverse events.…
Feb 27, 2019 · 1 share · 4,205 followersView post →
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Lucía Fuster Sanjurjo
@lfustersanjurjo · X
RT @PharmacoJournal: This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esoph…
Feb 26, 2019 · 6 shares · 536 followersView post →
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David Llantén
@d_llanten · X
RT @PharmacoJournal: This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esoph…
Feb 26, 2019 · 6 shares · 386 followersView post →
MP
Marc Probst
@probstMD · X
SRMA looking at Glucagon for esophageal FB or food impaction.
TL;DR - NO BENEFIT and significant increase in adverse events.
So, why do you still give it?
For fear of having the GI fellow scold us? Or simply another example of commission bias?
https://t.co/V9DP0kYRuO https://t.co/nJjpORwfXe
Feb 26, 2019 · 7 likes · 1 share · 960 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @PharmacoJournal: This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esoph…
Feb 26, 2019 · 6 shares · 6,686 followersView post →
P
Pharmacotherapy
@PharmacoJournal · X
This systematic review and meta‐analysis was performed to evaluate the efficacy and safety of glucagon for acute esophageal foreign body and food impactions. https://t.co/Ic8Qy8W5vR @accpemedprn https://t.co/Ba4AF0OfpK
Feb 26, 2019 · 13 likes · 6 shares · 11,870 followersView post →
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