PubHawk
February 2019 PMID 30800052

The Role of NMDA Receptors in Alzheimer's Disease.

Jinping Liu, Lirong Chang, Yizhi Song, Hui Li, Yan Wu

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Mentions

12
Peak: 4 in Jul 2021
across 3 sources since Feb 2019

Extended reach

99,892
potential audience

Total likes

75

Video views

2,210

Mentions per month

Feb 2019 – Mar 2025

Where it's discussed

  • X / Twitter8 posts
  • News3 articles
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone suggests moderate interest and impact, as seen in mentions of author names and institutions like Mayo Clinic, but the lack of detailed discussion shows limited engagement. The tone is mostly neutral, with some posts positioning the publication as a noteworthy contribution to understanding NMDAR's role in Alzheimer's, yet without concrete examples or exploring implications deeply.

AgreementNeither agree nor disagree

The discussions seem neutral with no clear strong disagreement or full endorsement, reflecting a balanced view on the research.

InterestModerate interest

There is some curiosity and moderate interest in the topic, evidenced by mentions of notable sources and researchers.

EngagementNeutral engagement

The reactions are somewhat superficial, with many posts just referencing the publication without deep analysis or commentary.

ImpactModerate impact

The discussions hint at the article's potential importance but lack substantial examples of its influence on practice or further research.

Abstract in brief

  • The text explains that early in Alzheimer's disease, the buildup of amyloid-beta peptides causes problems with synapses, mainly by affecting NMDA receptor (NMDAR) functions, leading to synaptic depression and the loss of dendritic spines.
  • Memantine, a drug that blocks NMDARs with low affinity, is used to treat moderate to severe AD, but scientists still don't fully understand how NMDAR dysfunction contributes to the disease, and research is ongoing.
  • The review emphasizes studying not just how NMDAR subunit expression changes in AD but also exploring some unusual ways that NMDARs might operate beyond their typical functions.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Frontiers - Neuroscience
@FrontNeurosci · X

The Role of NMDA Receptors in Alzheimer’s Disease: Jinping Liu, Lirong Chang, Yizhi Song, Hui Li, Yan Wu https://t.co/Un2EaMOtEN

Feb 15, 2019 · 8 likes · 2 shares · 80,742 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 23, 2021 · 1 like · 1 share · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Feb 9, 2022 · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 26, 2021 · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

RT @adamoprogresso: The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 26, 2021 · 1 share · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 20, 2021 · 3,257 followers View post →

All mentions

luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Feb 9, 2022 · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 26, 2021 · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

RT @adamoprogresso: The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 26, 2021 · 1 share · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 23, 2021 · 1 like · 1 share · 3,257 followers View post →
luca Leli.
@adamoprogresso · X

The Role of NMDA Receptors in Alzheimer’s Disease https://t.co/AS5giamuX1

Jul 20, 2021 · 3,257 followers View post →
TallDnm505
@NMCovid19 · X

@MayoClinic https://t.co/oGUhf8mKbA

Jul 6, 2020 · 474 followers View post →
Laboratorio de Neurocognición Social
@neurocogcialab · X

RT @FrontNeurosci: The Role of NMDA Receptors in Alzheimer’s Disease: Jinping Liu, Lirong Chang, Yizhi Song, Hui Li, Yan Wu https://t.co/Un…

Feb 15, 2019 · 2 shares · 170 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

The Role of NMDA Receptors in Alzheimer’s Disease: Jinping Liu, Lirong Chang, Yizhi Song, Hui Li, Yan Wu https://t.co/Un2EaMOtEN

Feb 15, 2019 · 8 likes · 2 shares · 80,742 followers View post →