Front Psychiatry February 2019 PMID 30804820

Systematic Review of Gut Microbiota and Major Depression.

Stephanie G Cheung, Ariel R Goldenthal, Anne-Catrin Uhlemann, J John Mann, Jeffrey M Miller, M Elizabeth Sublette

Mentions

56
Peak: 18 in Feb 2019
across 6 sources since Jan 2019

Extended reach

186,252
potential audience

Total likes

214

Video views

1,283

Mentions per month

Jan 2019 – Jul 2025

Where it's discussed

  • X / Twitter29 posts
  • News11 articles
  • YouTube7 videos
  • Blogs5 articles
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Several posts demonstrate interest by exploring specific bacterial taxa, such as Lachnospiraceae, and questioning the relevance of microbiota taxonomy versus functionality. The tone emphasizes curiosity and the potential importance of these findings, with phrases like 'implications for depression' and 'may be useful.' Although some commenters recognize limitations, overall, the discourse suggests a growing recognition of microbiota's role in depression, with words chosen to highlight interest and cautious optimism.

AgreementModerate agreement

Most posts acknowledge the significance of the systematic review, with some expressing curiosity about the correlation between gut bacteria and depression, indicating moderate support.

InterestHigh interest

Discussions show high curiosity, especially regarding the relationship between gut microbiota and mental health, reflected in questions and mentions of recent research implications.

EngagementModerate engagement

Posts mainly engage by referencing specific microbiota taxa and calling out aspects like functionality over taxonomy, showing some analysis but limited in-depth discussion.

ImpactModerate impact

While there is recognition that the review highlights a potential connection, many posts suggest the findings are preliminary, thus perceiving a moderate or emerging impact rather than a groundbreaking shift.

Abstract in brief

  • Recent studies show a link between the gut microbiome and psychiatric disorders like major depressive disorder (MDD), with evidence suggesting that gut bacteria from MDD patients can induce depression-like behaviors in rodents.
  • A systematic review of existing studies identified six studies comparing gut microbiota between MDD patients and healthy individuals, revealing 50 bacterial taxa that differed significantly between the two groups.
  • There wasn't a consistent finding across the studies regarding which bacteria are most relevant to MDD due to variations in patient characteristics and research methods, highlighting the complexity of the gut-brain connection in depression.

Top posts

Most liked on X and Bluesky
GutMicrobiota Health
@GMFHx · X

Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive disorders. This new systematic review highlights that taxonomy may not be as useful as functionality via @FrontPsychiatry https://t.co/U18Fw9FbGH

Feb 5, 2019 · 21 likes · 10 shares · 35,517 followers View post →
Scott Anderson
@Psychobiotic · X

Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/rt8y0dB0HL

Jan 26, 2019 · 8 likes · 4 shares · 18,562 followers View post →
Salud y Cerebro
@NMCerebral · X

Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Microbiota https://t.co/JTqFpKSLS1

Feb 5, 2019 · 3 likes · 5 shares · 1,347 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

Systematic Review of Gut Microbiota and Major Depression: Stephanie G. Cheung, Ariel R. Goldenthal, Anne-Catrin Uhlemann, J. John Mann, Jeffrey M. Miller, M. Elizabeth Sublette https://t.co/tgXJ8ZaP7c

Feb 11, 2019 · 2 likes · 1 share · 16,472 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

Systematic Review of Gut Microbiota and Major Depression https://t.co/hkmG6kX3yB Although probably doesn't take into the account the recent Valles-Colomer paper: https://t.co/fjSwzyatJa

Feb 27, 2019 · 1 like · 2 shares · 4,934 followers View post →
ʜᴀɴɴᴀ
@tamihania · X

@alizardx Interesting question...

Apr 27, 2019 · 1 like · 2,526 followers View post →

All mentions

Chauprade Christophe
@CY_Chauprade · X

@LaurentOzon @Gab__AI The data point to a positive correlation (Spearman’s rank correlation analysis; p < 0.05) between different taxa of Lachnospiraceae (specifically Anaerostipes, Blautia, Dorea, and Lachnospiraceae incertae sedis) and major depressive disorder (MDD) : https://t.co/Jzl5LINxlB

Jul 30, 2025 · 1 like · 200 followers View post →
Trained Marxist
@alonexsublime · X

@michellevacon @rottingcryptid @drjenwolkin and if not that, maybe this will help you https://t.co/w41ltOkrQQ

Sep 20, 2022 · 1 like · 36 followers View post →
Bongani Mayosi Health Sciences Library (BMHSL)
@uct_bmhsl · X

RT @bonillacuevas: Systematic Review of Gut Microbiota and Major Depression https://t.co/zv5XWI0VJH

Feb 11, 2021 · 2 shares · 1,598 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @bonillacuevas: Systematic Review of Gut Microbiota and Major Depression https://t.co/zv5XWI0VJH

Feb 11, 2021 · 2 shares · 6,714 followers View post →
ALEJANDRO BONILLA
@bonillacuevas · X

Systematic Review of Gut Microbiota and Major Depression https://t.co/zv5XWI0VJH

Feb 11, 2021 · 2 shares · 244 followers View post →
ʜᴀɴɴᴀ
@tamihania · X

@alizardx Interesting question...

Apr 27, 2019 · 1 like · 2,526 followers View post →
Thinking Autism
@TweetingAutism · X

RT @PaulWhiteleyPhD: Systematic Review of Gut Microbiota and Major Depression https://t.co/hkmG6kX3yB Although probably doesn't take into t…

Feb 27, 2019 · 2 shares · 14,358 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @PaulWhiteleyPhD: Systematic Review of Gut Microbiota and Major Depression https://t.co/hkmG6kX3yB Although probably doesn't take into t…

Feb 27, 2019 · 2 shares · 6,714 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

Systematic Review of Gut Microbiota and Major Depression https://t.co/hkmG6kX3yB Although probably doesn't take into the account the recent Valles-Colomer paper: https://t.co/fjSwzyatJa

Feb 27, 2019 · 1 like · 2 shares · 4,934 followers View post →
Iñaki
@inakimartiar · X

RT @NMCerebral: Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Mi…

Feb 12, 2019 · 5 shares · 27 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @FrontPsychiatry: Systematic Review of Gut Microbiota and Major Depression: Stephanie G. Cheung, Ariel R. Goldenthal, Anne-Catrin Uhlema…

Feb 11, 2019 · 1 share · 6,714 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

Systematic Review of Gut Microbiota and Major Depression: Stephanie G. Cheung, Ariel R. Goldenthal, Anne-Catrin Uhlemann, J. John Mann, Jeffrey M. Miller, M. Elizabeth Sublette https://t.co/tgXJ8ZaP7c

Feb 11, 2019 · 2 likes · 1 share · 16,472 followers View post →
Regie Layug
@ur_wellnessdoc · X

Is gut microbiota related to major #depression? https://t.co/HDK4kAj6xz

Feb 8, 2019 · 422 followers View post →
@pilar
@pilardlsh · X

RT @NMCerebral: Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Mi…

Feb 7, 2019 · 5 shares · 45 followers View post →
Antonio R
@AntonioRLRL · X

RT @NMCerebral: Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Mi…

Feb 6, 2019 · 5 shares · 9 followers View post →
Jeff Keelan
@jeff_keelan · X

RT @GMFHx: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive d…

Feb 5, 2019 · 10 shares · 1,955 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

RT @GMFHx: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive d…

Feb 5, 2019 · 10 shares · 16,472 followers View post →
Gilberto González
@giligon70 · X

RT @GMFHx: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive d…

Feb 5, 2019 · 10 shares · 423 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @GMFHx: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive d…

Feb 5, 2019 · 10 shares · 6,714 followers View post →
Dr Martin
@MartinRemains · X

RT @GMFHx: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive d…

Feb 5, 2019 · 10 shares · 26,289 followers View post →
GutMicrobiota Health
@GMFHx · X

Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for major depressive disorders. This new systematic review highlights that taxonomy may not be as useful as functionality via @FrontPsychiatry https://t.co/U18Fw9FbGH

Feb 5, 2019 · 21 likes · 10 shares · 35,517 followers View post →
Salud y Cerebro
@NMCerebral · X

RT @NMCerebral: Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Mi…

Feb 5, 2019 · 5 shares · 1,347 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @NMCerebral: Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Mi…

Feb 5, 2019 · 5 shares · 6,714 followers View post →
Salud y Cerebro
@NMCerebral · X

Systematic Review of Gut Microbiota and Major Depression https://t.co/yRCRQi7RW9 Via Front. Psychiatry #Depression #MDD #Microbiota https://t.co/JTqFpKSLS1

Feb 5, 2019 · 3 likes · 5 shares · 1,347 followers View post →
CureME~CFS
@Cure_ME_CFS · X

RT @Psychobiotic: Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/…

Jan 27, 2019 · 4 shares · 476 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @Psychobiotic: Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/…

Jan 26, 2019 · 4 shares · 769 followers View post →
René Alfonso
@ReneAlfon_zoo · X

RT @Psychobiotic: Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/…

Jan 26, 2019 · 4 shares · 413 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Psychobiotic: Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/…

Jan 26, 2019 · 4 shares · 6,714 followers View post →
Scott Anderson
@Psychobiotic · X

Systematic Review of Gut Microbiota and Major Depression. Taxonomy may not be as useful as functionality. https://t.co/rt8y0dB0HL

Jan 26, 2019 · 8 likes · 4 shares · 18,562 followers View post →