J Intensive Care March 2019 PMID 30923621

Gut integrity in critical illness.

Shunsuke Otani, Craig M Coopersmith

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Mentions

Peak: 2 in Nov 2025

across 4 sources since Mar 2019

Extended reach

1,121,881

potential audience

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22,413

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Mentions per month

Mar 2019 – Nov 2025

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AI synopsis

What people are saying

Discussions highlight the relevance of gut health in critical illness, with phrases like 'Gut integrity crucial for recovery' and mentions of specific researchers such as Otani S, reflecting moderate enthusiasm and acknowledgment of scientific details that suggest a thoughtful but not highly passionate discourse.

AgreementModerate agreement

Most posts acknowledge the importance of gut integrity in critical illness, showing moderate support for the publication.

InterestModerate interest

Discussions indicate some curiosity about the microbiome and mechanisms, but overall interest remains moderate.

EngagementModerate engagement

Comments include references to the authors and specific concepts like 'microbiome,' suggesting a level of thoughtful engagement.

ImpactModerate impact

Posts recognize the potential significance of understanding gut impairment for treatment, implying moderate perceived impact.

Abstract in brief

The gut is essential for maintaining health by absorbing nutrients and protecting against microbes, but in critical illness, its functions are severely impaired, leading to increased risk of organ failure.
During critical illness, the gut's protective barrier becomes compromised due to increased cell death, reduced cell renewal, and damaged tight junctions, resulting in a leaky gut that allows harmful substances to enter the bloodstream.
The gut microbiome shifts from healthy microbes to harmful bacteria, which can produce toxins that spread to other organs, contributing to multiple organ dysfunction; understanding this process may help develop better treatments in intensive care.]

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