Canagliflozin and renal outcomes in type 2 diabetes and nephropathy https://t.co/PmKRjwu73N vía @YouTube
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.
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Apr 2019 – Dec 2024Where it's discussed
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X / Twitter216 posts
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News72 articles
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Facebook27 posts
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Bluesky1 posts
AI synopsis
What people are saying
Many discussions reference the CREDENCE trial specifically, citing its findings that canagliflozin notably reduced the risks of kidney failure and cardiovascular events. Phrases like 'game changer' and 'groundbreaking study' are frequently used, emphasizing a strong confidence in the potential impact of these results on clinical practices.
The majority of discussions express strong agreement with the findings of the publication and the positive outcomes associated with canagliflozin.
Participants show a high level of interest in the implications of the study, highlighting its relevance in the context of diabetes and kidney disease management.
While many posts reference the publication and trials, the depth of engagement varies, with some simply sharing links without much personal commentary.
There is a general perception that the findings from the study will significantly influence treatment approaches for patients with type 2 diabetes and chronic kidney disease.
Abstract in brief
- Canagliflozin, an SGLT2 inhibitor, was tested in a trial with patients who have type 2 diabetes and chronic kidney disease, showing promising results for kidney health.
- The trial included 4,401 patients, comparing canagliflozin to a placebo, and was stopped early due to significant positive findings.
- Results indicated a 30% lower risk of severe kidney issues in the canagliflozin group, with further reductions in risks related to end-stage kidney disease and doubling of creatinine levels.
Top posts
Most liked on X and BlueskyCanagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Inpatient Lesson of the Day 5: We went on SGLT2 inhibitor rounds today. Reminded the team of the successes of these diabetes? CHF? renal? drugs. Also of how great it is to work in a system where
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/TCjLzmenAw
(Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC de ECA https://t.co/OESXN5cd3C Estudio original Y así lo vimos nosotros https://t.co/Jgl9lu8qpB https://t.co/IyvbrgFsCK
6) #Canagliflozin in the CREDENCE trial (
All mentions
SGLT2 Inhibitors for Kidney Disease: Clinical Insights and Benefits
This Harvard Medical School Continuing Education video explores how SGLT2 inhibitors like canagliflozin and dapagliflozin protect the kidneys, review key trial findings, and discuss updated guidelines, highlighting…
Impact of Salt Substitutes on Cardiovascular Health
Dr. Bruce Neal, a leading cardiologist, explores the cardiovascular implications of low sodium and high potassium diets. He presents findings from the 2021 SSASS Study, which involved 20,995 high-risk patients assessing…
Updates on Cardiological Research: Key Findings and Implications
The video provides a weekly update on cardiovascular updates in prominent journals. This episode highlights significant articles including findings on Canagliflozin as a promising treatment for patients with type 2…
Impact of SGLT2 Inhibitors on Kidney Health in Diabetes Patients
In this podcast, John Mandrola MD discusses SGLT2 inhibitors, their effects on chronic kidney disease, and highlights significant trial outcomes showing a 30% lower risk of severe kidney issues with Canagliflozin. A…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | New England Journal of Medicine https://t.co/05kyGRdOtI
@amitksvs References here: CREDENCE: https://t.co/HKhHT9kFqp FIDELIO-DKD: https://t.co/dXu1ZlqTjM SONAR: https://t.co/ELyfrCc3cD FLOW: https://t.co/qTVwBT392F
RT @cardiomet_CE: 35) In the #SGLT2i and #MRAtrials, pts w/ #T2D who received active treatment had ⬇️ in #UACR:
24a) @goKIDIGO 3.7 Sodium-glucose cotransporter-2 inhibitors (#SGLT2i) Some of the trials that support the use of SGLT2i in this population are: #CREDENCE
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | New England Journal of Medicine #67jds https://t.co/tnkL2gjbKe
24a) @goKIDIGO 3.7 Sodium-glucose cotransporter-2 inhibitors (#SGLT2i) Some of the trials that support the use of SGLT2i in this population are: #CREDENCE
https://t.co/3BOGFk8szL #SGLT2i
The new entry in France
15/ For more details on the data, check out the links below:
RT @cardiomet_CE: 35) In the #SGLT2i and #MRAtrials, pts w/ #T2D who received active treatment had ⬇️ in #UACR:
RT @cardiomet_CE: 35) In the #SGLT2i and #MRAtrials, pts w/ #T2D who received active treatment had ⬇️ in #UACR:
35) In the #SGLT2i and #MRAtrials, pts w/ #T2D who received active treatment had ⬇️ in #UACR:
35) In the #SGLT2i and #MRA trials, pts w/ #T2D who received active treatment had ⬇️ in #UACR:
RT @cardiomet_CE: 16) #SGLT2i also 1st line for glycemic control (2nd line for proteinuria) w/eGFR >20. Many clinical trials have shown imp…
RT @cardiomet_CE: 16) #SGLT2i also 1st line for glycemic control (2nd line for proteinuria) w/eGFR >20. Many clinical trials have shown imp…
16) #SGLT2i also 1st line for glycemic control (2nd line for proteinuria) w/eGFR >20. Many clinical trials have shown improved kidney & #CV outcomes (#DAPA_CKD #EMPA_REG_OUTCOME #EMPA_KIDNEY #CANVAS #CREDENCE, below), some even in pts w/o diabetes.
16) #SGLT2i also 1st line for glycemic control (2nd line for proteinuria) w/eGFR >20. Many clinical trials have shown improved kidney & #CV outcomes (#DAPA_CKD #EMPA_REG_OUTCOME #EMPA_KIDNEY #CANVAS #CREDENCE, below), some even in pts w/o diabetes.
25) #SGLT2i’s are recommended in patients with #T2D and #CKD with an #eGFR of ≥20 mL/min regardless of #HbA1c. In #CREDENCE, #canagliflozin reduced primary & renal-specific composite outcomes & was consistent across subgroups.
25) #SGLT2i’s are recommended in patients with #T2D and #CKD with an #eGFR of ≥20 mL/min regardless of #HbA1c. In #CREDENCE, #canagliflozin reduced primary & renal-specific composite outcomes & was consistent across subgroups.
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
RT @drdschwartzmd: This study showed that in patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascula…
RT @drdschwartzmd: 4) CREDENCE: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy The first primary CKD study to show th…
This study showed that in patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group. https://t.co/MuDV2LvqO0
4) CREDENCE: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy The first primary CKD study to show that an SGLT2i can reduce kidney outcomes in patients with diabetes and kidney disease. https://t.co/WjhQAKeJbQ
We know from CREDENCE, DAPA-CKD and EMPA-KIDNEY that SGLT2i + ACEi or ARB (aka RAASi) is safe and effective at reducing renal/CV endpoints https://t.co/qBwox3fWyp https://t.co/IlxMKlDJpB https://t.co/1jF5YfzLHz
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
@jpcostabel @secardiologia @SENefrologia @SVNefro @jlgorriz @nephondemand @CristobMorales @SIAC_cardio @AmbrizMau @mvaduganathan @brendonneuen @JuliaSellerm @Dr_Manito @purviparwani @rafavidalperez @jorgericof Miremos los resultados con CANA en 100% DM2 https://t.co/iFr29uSViz
RT @ckd_ce: 7) This recommendation is based on strong evidence that #SGLT2i reduce #CKD progression, #HF, and #ASCVD risk in patients with…
RT @ckd_ce: 8) These trials enrolled pts w/ #albuminuria: #CREDENCE: ACR >/=300 mg/g #DAPA_CKD: ACR >/=200 mg/g & showed significant benefi…
RT @ckd_ce: 7) This recommendation is based on strong evidence that #SGLT2i reduce #CKD progression, #HF, and #ASCVD risk in patients with…
RT @ckd_ce: 7) This recommendation is based on strong evidence that #SGLT2i reduce #CKD progression, #HF, and #ASCVD risk in patients with…
8) These trials enrolled pts w/ #albuminuria: #CREDENCE: ACR >/=300 mg/g #DAPA_CKD: ACR >/=200 mg/g & showed significant benefit for composite outcomes/EPs:
7) This recommendation is based on strong evidence that #SGLT2i reduce #CKD progression, #HF, and #ASCVD risk in patients with #T2D and CKD #VisualAbstract by @brendonneuen @whatsthegfr #CREDENCE
RT @AcidosisTubular:
#099 Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy N Engl J Med 2019;380:2295-306. CREDENCE試験 CKDを合併した2型糖尿病で、カナグリフロジンはプラセボと比較して、腎関連の複合エンドポイントを改善する
カナグリフロジンの適応追加がきっかけになった臨床試験 https://t.co/aiv1tjD5H7
1. Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJL, Charytan DM, et al. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. N Engl J Med [Internet]. 2019;380(24):2295–306. Available from: https://t.co/5yirfAYxyC
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy - Medical English https://t.co/Ms5lHMwBQ6
RT @medical_910: #CardioJapan #NEJM https://t.co/jCrlOacHwe 一言でいうと 2型糖尿病(アルブミン尿+)の患者にカナグリフロジン投与したらアウトカムがめちゃくちゃ改善した件www N Engl J Med. 2019…
RT @IshiyakuApp: カナグル主要試験 【CREDENCE試験】 アルブミン尿を有する慢性腎臓病(30<eGFR<90)を伴う2型DMに対して、プラセボと比較して、カナグリフロジン100mgとプラセボを比較して、追跡期間中央値2.62年における腎不全および心血管イベ…
カナグル主要試験 【CREDENCE試験】 アルブミン尿を有する慢性腎臓病(30<eGFR<90)を伴う2型DMに対して、プラセボと比較して、カナグリフロジン100mgとプラセボを比較して、追跡期間中央値2.62年における腎不全および心血管イベントの発生リスクを30%有意に低下させた https://t.co/Z5MWU7C2se
6) #Canagliflozin in the CREDENCE trial (
RT @ISNeducation: 17/27 In 2018, the results of the CREDENCE study were presented during the #ISNWCN. We had a new class of medication (SGL…
17/27 In 2018, the results of the CREDENCE study were presented during the #ISNWCN. We had a new class of medication (SGLT2-i) to treat DM CKD after a long period without innovations. Check DOI: 10.1056/NEJMoa1811744 #ISNTweetorial https://t.co/fD8RHnmMK6
RT @kidney_boy: @_GoozNews The entire article never mentions that this one of only drugs to reduce total mortality. Shameful. 2202 people…
@_GoozNews The entire article never mentions that this one of only drugs to reduce total mortality. Shameful. 2202 people, 2.6 years 11 cases of DKA In that time there was 30 fewer CV deaths & 60 fewer people on dialysis with Cana https://t.co/A3M8K4jIda https://t.co/YLMGX1CbCX
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/ZCaZLPAWcL
RT @Diabetes_SEMI: Articulo que refuerza el tratamiento de la #diabetes En pacientes con diabetes tipo 2 y enfermedad renal, el riesgo de…
40) CREDENCE (DOI: 10.1056/NEJMoa1811744) showed us that canagliflozin in patients with T2D and albuminuric CKD significantly outperformed placebo on renal outcomes. The RR of the renal-specific composite of ESRD, a doubling of the creat level, or death from renal causes . . .
RT @cardiomet_CE: Now moving on to #CKD @brendonneuen presented this image Projected from the CREDENCE Trial (https://t.co/n3Wg4N765o)…
RT @cardiomet_CE: Now moving on to #CKD @brendonneuen presented this image Projected from the CREDENCE Trial (https://t.co/n3Wg4N765o)…
RT @cardiomet_CE: Now moving on to #CKD @brendonneuen presented this image Projected from the CREDENCE Trial (https://t.co/n3Wg4N765o)…
RT @cardiomet_CE: Now moving on to #CKD @brendonneuen presented this image Projected from the CREDENCE Trial (https://t.co/n3Wg4N765o)…
@bmj_latest @will_s_t https://t.co/GLHnSOOxDq
@steve__72 @6catsCatholic @sbABetterLeader @AstraZenecaUS The data on post transplant is soft. The CKD data is compelling and strong. Best (CKD, not a transplant) studies to look are CREDENCE (all diabetics): https://t.co/A3M8K4jIda and DAPA-CKD (1/3rd non-diabetes): https://t.co/OD19ytjLIZ https://t.co/kxPPPp44h0
RT @drjohnm: Post-hoc studies always deserve caution but the main trial results were positive https://t.co/r9PGDd11Fq #SGLT2i continue to…
Post-hoc studies always deserve caution but the main trial results were positive https://t.co/r9PGDd11Fq #SGLT2i continue to impress. These are no longer just diabetic drugs. https://t.co/2ba6QXTOfF
https://t.co/ZNjPrBk67M
@LeiaRx @mikejohansenmd https://t.co/ra3lL6So51
@pabloange @goKDIGO That is a post hoc analysis of CREDENCE (subgroup analysis of patients with GFR < 30)
https://t.co/gypbhQE94g
https://t.co/fisXSvINOI Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy Gilton Javier Jimenez Quezada. Medical English. Dr. John Moscoso. 4 "A"
RT @UREssien: Inpatient Lesson of the Day 5: We went on SGLT2 inhibitor rounds today. Reminded the team of the successes of these diabetes…
RT @UREssien: Inpatient Lesson of the Day 5: We went on SGLT2 inhibitor rounds today. Reminded the team of the successes of these diabetes…
Inpatient Lesson of the Day 5: We went on SGLT2 inhibitor rounds today. Reminded the team of the successes of these diabetes? CHF? renal? drugs. Also of how great it is to work in a system where
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
Nutshell #113: When compared to #placebo, the use of #canagliflozin in patients with type 2 #diabetes significantly reduced the risk for #cardiovascular or renal death, #dialysis, myocardial #infarction, and #stroke. Article: https://t.co/THaFYYhoLD #research #medicine #science https://t.co/GJ6QbvhoM3
The correct answer is D. Empagliflozin slows progression of CKD (Creedence Trial) and decreases HF Mort. (Empa-Reg). Weirdly enough Dapagliflozin even decreases HF mortality in those without DM (Dapa-HF)! https://t.co/uQgWHBCtOK https://t.co/OXfmH0xdNX https://t.co/ejiDl9xakh https://t.co/kOM3bZIjde
RT @IanJStewart3: @chungk1031 I’m a nephrologist, so the kidney studies are particularly interesting to me. CREDENCE. https://t.co/mRoOlfX…
RT @IanJStewart3: @chungk1031 I’m a nephrologist, so the kidney studies are particularly interesting to me. CREDENCE. https://t.co/mRoOlfX…
@chungk1031 I’m a nephrologist, so the kidney studies are particularly interesting to me. CREDENCE. https://t.co/mRoOlfX0hm
RT @kamkalantar: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy (CREDENCE) Trial - American College of Cardiology http…
RT @kamkalantar: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy (CREDENCE) Trial - American College of Cardiology http…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy (CREDENCE) Trial - American College of Cardiology https://t.co/riNu59kchc
@Heart_SCCT @DrMarthaGulati @JAMACardiology @lesleejshaw Congratulations everyone
RT @Diabetes_SEMI: Articulo que refuerza el tratamiento de la #diabetes En pacientes con diabetes tipo 2 y enfermedad renal, el riesgo de…
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to current standard of care ca. 2019 from @NEJM #VisualAbstract by @brendonneuen #Nephpearls
#Canagliflozin reduces heart failure in patients with T2-DM & CKD (#CREDENCE trial). | NEJM Another #SGLT2i success story! https://t.co/rRs3f5Pbgy https://t.co/Oq3URS9AGM
RT @CRForumUS: Congratulations to Dr. Kenneth Mahaffey on receiving a Top 10 Distinguished Clinical Research Achievement Award! Learn more…
Congratulations to Dr. Kenneth Mahaffey on receiving a Top 10 Distinguished Clinical Research Achievement Award! Learn more about the study, "Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy," in his Top 10 video @StanfordMed #TopTen https://t.co/FVqJt60vnp https://t.co/aClwTK74sq
RT @VictorPinoJr1: Canagliflozin and renal outcomes in type 2 diabetes and nephropathy https://t.co/PmKRjwu73N vía @YouTube
RT @VictorPinoJr1: Canagliflozin and renal outcomes in type 2 diabetes and nephropathy https://t.co/PmKRjwu73N vía @YouTube
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy https://t.co/PmKRjwu73N vía @YouTube
RT @kamkalantar: #Canagliflozin and #Renal #Outcomes in Type 2 #Diabetes and #Nephropathy (#CREDENCE) #Trial Apr 22, 2020, Robin Lo, MD;…
RT @kamkalantar: #Canagliflozin and #Renal #Outcomes in Type 2 #Diabetes and #Nephropathy (#CREDENCE) #Trial Apr 22, 2020, Robin Lo, MD;…
RT @kamkalantar: #Canagliflozin and #Renal #Outcomes in Type 2 #Diabetes and #Nephropathy (#CREDENCE) #Trial Apr 22, 2020, Robin Lo, MD;…
RT @kamkalantar: #Canagliflozin and #Renal #Outcomes in Type 2 #Diabetes and #Nephropathy (#CREDENCE) #Trial Apr 22, 2020, Robin Lo, MD;…
#Canagliflozin and #Renal #Outcomes in Type 2 #Diabetes and #Nephropathy (#CREDENCE) #Trial Apr 22, 2020, Robin Lo, MD; Kam Kalantar-Zadeh, MD; Connie @ConnieMRhee, MD. - American College of Cardiology https://t.co/Jfiyno7SSf
RT @ACCinTouch: Read a new expert analysis on the Canagliflozin and Renal Outcomes in Type 2 #Diabetes and Nephropathy (CREDENCE) Trial: ht…
Read a new expert analysis on the Canagliflozin and Renal Outcomes in Type 2 #Diabetes and Nephropathy (CREDENCE) Trial: https://t.co/siUXnFSnU3
Congratulations to Dr. Kenneth Mahaffey on his Distinguished Clinical Research Achievement Award for his incredible study "Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy" @StanfordMed #TopTen https://t.co/FVqJt60vnp
The CANVAS and CREDENCE trial both showed that patients with diabetes treated with canagliflozin experienced less cardiovascular events, and those in the CREDENCE trial had less kidney failure. https://t.co/LFZLnCKg8D https://t.co/WAiq5u3Pj7
This works w/ the effect of ACEi/ARB which inhibit vasoconstriction of the efferent arteriole; SGLT2i can still provide improvement in renal outcomes for diabetic kidney disease in pts on maximum doses of ACE inhibitor (which increases efferent flow). https://t.co/WAiq5u3Pj7
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
Dr. Cody McCoy – Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/tP0zUZ7513
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to current standard of care ca. 2019 from @NEJM #VisualAbstract by @brendonneuen #Nephmadness 2️⃣
RT @brendonneuen: Canagliflozin reduces the risk of kidney failure or death due to cardiovascular or kidney disease by 30% compared to curr…
@askrenal @NephJC @cwgillihan Yes! A subgroup analysis of the CREDENCE trial shows that ~4% of the patients had, in fact, an eGFR < 30 mg/dL. Also, the patients were continued on canagliflozin treatment per protocol until initiation of dialysis or kidney transplantation. https://t.co/pXfakuS5Jw
RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/kxaKbKleSn #clinicalresearch #clinicaltrials #endpointadjudication #electronichealthrecords #clinicalstudies #digitalsignatures #patientengagement #pharmacovigilance #eclinical https://t.co/sHSSLOq5QK
RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…
RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…
RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…
1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a brief overview of CANVAS & CREDENCE Trials to review why an SGLT2i was started. CANVAS Trial: https://t.co/mfw2cI9buz CREDENCE Trial: https://t.co/2rGjYf92WQ
@GustavoFdz @doctormacias https://t.co/K2KlwU7CgP No es tan nuevo pero espero sea de utilidad. Saludos!
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
https://t.co/gEJ0sbYyOL アルブミン尿がある2型糖尿病患者において、カナグリフロジン100mgを投与した群はプラセボ群と比し心血管イベント、脳卒中リスクが低かった。
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
RT @edgarvlermamd: CREDENCE: Canagliflozin reduces the risk of kidney failure or death due to CV or kidney disease by 30% compared to curre…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
RT @Diabetes_SEMI: Estudio CREDENCE https://t.co/cgTY41Vuno ▶️4401 pacientes con DM2 y ERC asignados a canagliflozina o placebo ▶️Paci…
#SGLT2阻害薬 の腎アウトカムを主要評価項目とした初の大規模臨床試験。 #カナグリフロジン による腎保護作用が示されました.( #CREDENCE試験) Volume 380:2295-2306 June 13, 2019 #Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/EXVGpWq3CF
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/SE7STVv9hu
RT @Physns1stWatch: Featured research includes: —Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Preliminary Repo…
Featured research includes: —Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Preliminary Report —Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy —Targeting Huntingtin Expression in Patients with Huntington’s Disease https://t.co/fTIJEbj0jT
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/FzSGMeoHhT
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. https://t.co/5KebpaN8yU #jsphcs2019
Open Access UCL Research: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/9SbnojdphF
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/xMYieHz8pJ
RT @kniraz7: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM #CREDENCE sounds like a game-changer! https://t.co…
NEJM Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy 1 Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation 2 IMAGES IN CLINICAL MEDICINE Disseminated... https://t.co/jLngetLNAW
正解は、SGLT2阻害薬です。 最近出された論文で、ここ最近ではSGLT2阻害薬がバンバン処方されてます。 ただ、ケトアシドーシスになるという副作用も報告されているので注意が必要です。 Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy N Engl J Med 2019;380:2295-306
@mugitya_oisiiyo 今回のやつはこの論文ですね
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
RT @rincondesisifo: (Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC…
(Evid Based Med) Prevención de la enfermedad CV y el fallo renal con iSGLT2 en pac con DM2 https://t.co/LU0xgtHD4c REC de ECA https://t.co/OESXN5cd3C Estudio original Y así lo vimos nosotros https://t.co/Jgl9lu8qpB https://t.co/IyvbrgFsCK
RT @NephJC: T-1 hour to the European #NephJC on the CREDENCE trial—Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. Hop…
#RED2019 https://t.co/ues3azFM5x
Want to learn more? #weeklyJClub Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/uQzYWrcoJZ
RT @RealTNagasawa: CREDENCE試験。腎予後を劇的に改善、カナグリフロジン群では血圧が-3.3mmHg、体重-0.8kgである事には注意。また人種構成は白人が65%強、アジア人が20%、黒人が5%(EMPA研究も似たような構成) Canagliflozin…
CREDENCE試験。腎予後を劇的に改善、カナグリフロジン群では血圧が-3.3mmHg、体重-0.8kgである事には注意。また人種構成は白人が65%強、アジア人が20%、黒人が5%(EMPA研究も似たような構成) Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/XraoCID16V
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/SNXawYRk0v
Just Released ...... Amazing info Perkovic, V. et al. (2019) ‘Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy’, New England Journal of Medicine. Massachusetts Medical Society, 380(24), pp. 2295–2306. doi: 10.1056/NEJMoa1811744.
#EBM EvidenceAlerts | Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. https://t.co/SFgX3WpCQh
(SIETES) Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/EjYSLkmywX
RT @kimche: This year we are starting @NU_IntMed EBMondays: Journal club on 1st Monday of each block.
This year we are starting @NU_IntMed EBMondays: Journal club on 1st Monday of each block.
Amazing results and very well conducted trial: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/ELlOxqfY4l
HEALTH Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://t.co/N4538fLdQi
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. https://t.co/wmJshdyLGi
The Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy (#CREDENCE) trial suggests that Canagliflozin provides renal & #CV protection in patients with #T2D with chronic kidney disease (#CKD). https://t.co/si2gJzvQvX
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/O8xMdiB3nH
RT @cristinatejerap: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/TCjLzmenAw
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/ttRbKLAHmR
RT @ggimenezendocri: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/gBGAve1JRF sglt2 inhibitors sh…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM is this a class-effect or single related to cana? https://t.co/ASZ99t72MA
RT @NephroLeuven: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM - game changing class effects of the SGLT2 inh…
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @Foroactua: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/LZTPx3UdBl … https…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/LZTPx3UdBl … https://t.co/0kvv6TcEYa https://t.co/gYa3L4CPiW
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/Xpb1xCLT4t
RT @cristinatejerap: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/TCjLzmenAw
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM - game changing class effects of the SGLT2 inhibitors! https://t.co/QVGM3rOaW8
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | @NEJM @diabeteSEEN https://t.co/TCjLzmenAw
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/4HX5Ds9Lga
SGLT2 inhibitors are on quite a roll... Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/lfoAhVJhLL
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @codeblueflower: 利益相反があることがそんなに悪なのか?今週のNEJMの1本目、COI山盛りに書いてあるで。でもその論文自体が無価値にはならんでしょう。逆に「あるから」だけで切り捨てるのは読めなさすぎでは? Canagliflozin and Renal…
RT @codeblueflower: 利益相反があることがそんなに悪なのか?今週のNEJMの1本目、COI山盛りに書いてあるで。でもその論文自体が無価値にはならんでしょう。逆に「あるから」だけで切り捨てるのは読めなさすぎでは? Canagliflozin and Renal…
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/D7wph1JH15
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @codeblueflower: 利益相反があることがそんなに悪なのか?今週のNEJMの1本目、COI山盛りに書いてあるで。でもその論文自体が無価値にはならんでしょう。逆に「あるから」だけで切り捨てるのは読めなさすぎでは? Canagliflozin and Renal…
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/248uh4IELf
RT @almucastro01: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/JnyEFye0qA
RT @AmarPut: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/zqhPaxuMkp
RT @codeblueflower: 利益相反があることがそんなに悪なのか?今週のNEJMの1本目、COI山盛りに書いてあるで。でもその論文自体が無価値にはならんでしょう。逆に「あるから」だけで切り捨てるのは読めなさすぎでは? Canagliflozin and Renal…
RT @codeblueflower: 利益相反があることがそんなに悪なのか?今週のNEJMの1本目、COI山盛りに書いてあるで。でもその論文自体が無価値にはならんでしょう。逆に「あるから」だけで切り捨てるのは読めなさすぎでは? Canagliflozin and Renal…
@Perene9 Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/mz0qS1pJ7G
RT @PGee51: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/4NCH3woZoW
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://t.co/4NCH3woZoW
RT @docramiro: Esto para disminuir progresión de daño renal y riesgo cardiovascular. Esto por el estudio #CREDENCE donde se encontró reducc…
Esto para disminuir progresión de daño renal y riesgo cardiovascular. Esto por el estudio #CREDENCE donde se encontró reducción de ambos en un 30% y 20% respectivamente. Link: https://t.co/oFjumkHWYe, https://t.co/zW1pbAngmZ https://t.co/bgFCyMqYgk
https://t.co/e0OIhmoUJB
@garyromakable @kidney_boy Awesome results with SLGT2, but risks of genital infections and euDKA are concerning (seen 3 SGLT2-induced euDKA). I’m a huge advocate but rx only if patient has excellent Endo follow up. https://t.co/wMbYFjwNfy
RT @CristobMorales: https://t.co/hoyQNZCHH2 U.S. FDA Grants Priority Review of INVOKANA® (canagliflozin) for the Treatment of Chronic Kidne…
https://t.co/hoyQNZCHH2 U.S. FDA Grants Priority Review of INVOKANA® (canagliflozin) for the Treatment of Chronic Kidney Disease in Patients with Type 2 Diabetes https://t.co/FsO9lwMPaP #CREDENCETrial https://t.co/p8kBfPuh62
RT @redGDPS: Que nos dice el #CREDENCE en funciones renales <60% #SEDiab19 https://t.co/TLsun5LFqj https://t.co/rBSK0ziXzu
RT @redGDPS: Que nos dice el #CREDENCE en funciones renales <60% #SEDiab19 https://t.co/TLsun5LFqj https://t.co/rBSK0ziXzu
Que nos dice el #CREDENCE en funciones renales <60% #SEDiab19 https://t.co/TLsun5LFqj https://t.co/rBSK0ziXzu
RT @DRKAMALAYOUB: استخدام دواء ال canagliflozin في علاج داء السكري يخفض نسبة الاصابة بالفشل الكلوي بنسبة الثلث . https://t.co/JzzNtMrliS
RT @DRKAMALAYOUB: استخدام دواء ال canagliflozin في علاج داء السكري يخفض نسبة الاصابة بالفشل الكلوي بنسبة الثلث . https://t.co/JzzNtMrliS
استخدام دواء ال canagliflozin في علاج داء السكري يخفض نسبة الاصابة بالفشل الكلوي بنسبة الثلث . https://t.co/JzzNtMrliS
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa1811744#.XLPWBfhXvio.twitter