Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs).

Marco Fiorillo, Fanni Tóth, Federica Sotgia, Michael P Lisanti

April 2019 Aging (Albany NY)

Synopsis of Social media discussions

The discussions demonstrate strong agreement and curiosity, with examples like mentions of a 90% reduction in cancer cells, calls for clinical trials, and observations about the therapy being less toxic. Words like 'potent', 'game changer', and 'must consider' reveal excitement and perceived significance, indicating a high level of engagement and perceived impact.

A
Agreement
 Moderate agreement

Most discussions support the effectiveness of the combination therapy, highlighting its potential to reduce cancer cell growth significantly.

I
Interest
 High level of interest

Participants show high interest by discussing potential clinical applications, such as starting trials, and noting the therapy's advantages over traditional methods.

E
Engagement
 High engagement

Several comments delve into the mechanisms, potential benefits, and even anecdotal evidence, indicating deep engagement and curiosity.

I
Impact
 High level of impact

The overall tone suggests these discussions see this research as impactful, with some highlighting it as a possible game-changer in cancer treatment.

Social Mentions

YouTube

2 Videos

Bluesky

1 Posts

Facebook

6 Posts

Twitter

56 Posts

News

10 Articles

Metrics

Video Views

108

Total Likes

103

Extended Reach

83,845

Social Features

75

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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  • Marek Bogacki
    @documentavi (Twitter)

    @questmoosa article https://t.co/ANnPo2QkN4 study https://t.co/d4fLA7329Y also • Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/PySGhaljCh grok https://t.co/CXXlCzPQKr .
    view full post

    September 28, 2025

    3

  • Rene Sugar
    @renesugar.bsky.social (Bluesky)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) www.aging-us.com/article/1019...
    view full post

    May 19, 2025

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  • Rene Sugar
    @renesugar (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/4wjOiSn0As
    view full post

    May 19, 2025

    1

  • Rene Sugar
    @renesugar (Twitter)

    @DrZeedMD Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/nJ9wHGgX2o
    view full post

    March 27, 2025

  • Dawn Cole
    @ColeDawnu (Twitter)

    RT @localhostsci: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    February 5, 2025

    1

  • Ally Jonsson
    @AllyJonsson (Twitter)

    Triple therapy of low dose common drugs reduced cancer in 3 breast cancer cell lines by 90% Azithromycin, Doxycycline & Vitamin C Let's get the clinical trials happening! Cheaper & less toxic than typical chemotherapy & radiation! https://t.co/2HhtshIC0P
    view full post

    July 3, 2024

  • Van
    @patternfollower (Twitter)

    @AcctBannedIn321 @Blagosklonny https://t.co/ECOcVQWAPd
    view full post

    May 12, 2024

  • Van
    @patternfollower (Twitter)

    @Blagosklonny Dr. B, take a look at this paper on Cancer and Longevity protocol. Very interesting just like verapamil. https://t.co/p7LSjhTz04
    view full post

    May 12, 2024

  • Dr. Lora Chamberlain
    @FrackingFreeIL (Twitter)

    RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…
    view full post

    March 6, 2024

    3

  • Good Luck
    @GoodLuck_BSafe (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/nY42h05Ksz
    view full post

    December 24, 2023

  • Dammian Miller
    @DammianMiller (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/NosaodxZ7B
    view full post

    November 26, 2023

  • luthfi darmawan
    @luthffffi (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/1syV4Io6ob
    view full post

    November 26, 2023

    1

  • OxS
    @splusoh (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/9zASY53QnO
    view full post

    November 26, 2023

  • American Dreamer
    @ARebel562 (Twitter)

    RT @Orlando_uy: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating canc…
    view full post

    September 27, 2023

    2


  • @Orlando_uy (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells. https://t.co/8SKUXxVjhB
    view full post

    September 27, 2023

    1

    2

  • Rene Sugar
    @renesugar (Twitter)

    @ErinSandersNP Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/oAnyLnbKld
    view full post

    September 8, 2023

    2

  • Rene Sugar
    @renesugar (Twitter)

    @AmandaB55744931 @Naomi_D_Harvey Someone told me their dog was given doxycycline for palliative reasons and it ended up treating their dog's cancer; dogs make their own vitamin C. eg. Doxycycline, Azithromycin and Vitamin C https://t.co/4wjOiSn0As https://t.co/CijWit6B0Z https://t.co/mtrRRt2EcH
    view full post

    January 4, 2023

    1

  • Rene Sugar
    @renesugar (Twitter)

    RT @renesugar: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cance…
    view full post

    December 31, 2022

    1

  • Yurii
    @Yurii08720681 (Twitter)

    @bhushanlab what do you think about doxycycline and azithromycin? - as synolytics, in this article the anti-cancer strategy is discussed, but anti-aging is mentioned. https://t.co/amEVBGpuUC
    view full post

    October 17, 2022

  • Vic Martinez
    @truthseeker1961 (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • Slawomir
    @Slawomi18369321 (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • Kevin Quirk
    @KevinQuirk9 (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • Birsen
    @BTUR3 (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • Carsten Erdmann
    @Dr_C_Erdmann (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • SamOlivetree
    @SamOlivetree (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    October 1, 2022

    9

  • Orioso de Rohars
    @Orioso_Rohars (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    September 30, 2022

    9

  • Sum_1
    @a_place_n_time (Twitter)

    RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…
    view full post

    September 30, 2022

    9

  • Mark
    @Supertelomerase (Twitter)

    @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline (to impair mitochondrial biogenesis) killed cancer stem cells. Here it is: https://t.co/MBI2saUEWO
    view full post

    September 30, 2022

    53

    9

  • Yurii
    @Yurii08720681 (Twitter)

    @haidut of: Doxycycline, Azithromycin and Vitamin C (DAV) the result is more than 90% https://t.co/amEVBGoX54
    view full post

    September 27, 2022

    1

  • LeAnne LawtonTancred
    @LeAnneTancred (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells. https://t.co/HS2sV5geHg
    view full post

    April 8, 2022

  • LeAnne LawtonTancred
    @LeAnneTancred (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicat… https://t.co/HS2sV5geHg
    view full post

    April 8, 2022

  • The Good Life 4 Us
    @thegoodlife4us (Twitter)

    RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…
    view full post

    January 18, 2022

    3

  • Truth Seeker
    @Amy21407287 (Twitter)

    RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…
    view full post

    January 18, 2022

    3

  • J
    @QuantumMed3 (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). https://t.co/HYwsLzjG5V
    view full post

    January 18, 2022

    4

    3

  • Rene Sugar
    @renesugar (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/7jXroYC0D8 "Combination of low-dose Doxycycline and Azithromycin reduces glycolysis and glycolytic reserve."
    view full post

    October 28, 2021

    1

    1

  • localhostscience
    @localhostsci (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)
    view full post

    September 29, 2021

    1

  • AntiAgify - Science will set you free
    @AntiAgify (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). Plus: "Azithromycin is an anti-aging drug that behaves as a senolytic... " https://t.co/iXOjmrMolu
    view full post

    October 4, 2020

    2

  • Black Bird
    @DopeBodhi (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/jYVliJIAdN
    view full post

    August 1, 2020

  • Black Bird
    @DopeBodhi (Twitter)

    @RealBrianWatt Check out https://t.co/3hn8Xfl2Ye Doxycycline, Azithromycin and Vitamin C (DAV): A Potent Combination Therapy for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs)
    view full post

    June 10, 2020

  • Mona-Lisa
    @Obamasshadow (Twitter)

    @ebmpsykiatri @miraaksoys https://t.co/gQ5lwViu0A
    view full post

    May 17, 2020

    2

  • Alexander Dreyzen
    @ADreyzen (Twitter)

    @Blagosklonny Does this cocktail also inhibit normal stem cells proliferation? I couldn't find the answer here: https://t.co/3tleVGcSHT
    view full post

    January 14, 2020

  • Leon Yuan
    @yxlearn (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). - PubMed - NCBI https://t.co/tDcHS6tYbK
    view full post

    December 9, 2019

  • Zhi Sheng
    @zhishenglab (Twitter)

    RT @OpenResSalford:
    view full post

    May 4, 2019

    1

  • Open Research UoS
    @OpenResSalford (Twitter)


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    May 3, 2019

    1

    1

  • Women's Health News
    @womens_womens (Twitter)

    RT @womens_womens: Doxycycline Azithromycin and Vitamin C DAV A potent combination therapy for targeting mitochondria and eradicating cance…
    view full post

    April 22, 2019

    1

  • Philo
    @ingridjota (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 21, 2019

    10

  • Dave Grawoig, Ph.D.
    @grawoig (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 21, 2019

    10

  • L. J.
    @lmj612 (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 21, 2019

    10

  • Likepiterathome
    @likepiterathome (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 21, 2019

    10

  • JoaquimLamora
    @JoaquimLamora (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 21, 2019

    10

  • Mitochondrial News
    @MitochondriaNe1 (Twitter)

    #mitochondria Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). https://t.co/WFmSZ2jAQH via @MitochondriaNe1
    view full post

    April 21, 2019

    1

  • Marilyn Gavranovic
    @MarilynGavrano5 (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 20, 2019

    10

  • ☀️LRstardust⭐️
    @RotmeLingnoi (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 20, 2019

    10

  • Adi Setyawan MD
    @AdiSObGyn (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 20, 2019

    10

  • Joe Gordon
    @josephwgordon (Twitter)

    RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…
    view full post

    April 20, 2019

    10

  • MitoMedicine
    @MitoMedicine (Twitter)

    Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). - PubMed - NCBI https://t.co/DCDUtFH6zw
    view full post

    April 20, 2019

    20

    10

  • Women's Health News
    @womens_womens (Twitter)

    Doxycycline Azithromycin and Vitamin C DAV A potent combination therapy for targeting mitochondria and eradicating cancer stem cells CSCs.: Here we devised a new strategy for eradicating cancer stem cells CSCs via a "syntheticmetabolic" approach… https://t.co/RsWdy7pspk
    view full post

    April 20, 2019

    1

Abstract Synopsis

  • This study introduces a new cancer treatment strategy that combines two FDA-approved antibiotics, Doxycycline and Azithromycin, with Vitamin C to target cancer stem cells (CSCs) by disrupting their mitochondrial function.
  • The approach works by inhibiting mitochondrial protein synthesis through the antibiotics and inducing mitochondrial biogenesis via oxidative stress from Vitamin C, leading to a dramatic 90% reduction in CSC growth in breast cancer cells.
  • Using sub-antimicrobial doses helps avoid antibiotic resistance issues, and the findings suggest this combination could be a promising and innovative way to target tumor growth and improve overall health.