Aging (Albany NY) April 2019 PMID 31002656

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs).

Marco Fiorillo, Fanni Tóth, Federica Sotgia, Michael P Lisanti

Mentions

75
Peak: 13 in Apr 2019
across 5 sources since Apr 2019

Extended reach

83,845
potential audience

Total likes

103

Video views

108

Mentions per month

Apr 2019 – Sep 2025

Where it's discussed

  • X / Twitter56 posts
  • News10 articles
  • Facebook6 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions demonstrate strong agreement and curiosity, with examples like mentions of a 90% reduction in cancer cells, calls for clinical trials, and observations about the therapy being less toxic. Words like 'potent', 'game changer', and 'must consider' reveal excitement and perceived significance, indicating a high level of engagement and perceived impact.

AgreementModerate agreement

Most discussions support the effectiveness of the combination therapy, highlighting its potential to reduce cancer cell growth significantly.

InterestHigh interest

Participants show high interest by discussing potential clinical applications, such as starting trials, and noting the therapy's advantages over traditional methods.

EngagementHigh engagement

Several comments delve into the mechanisms, potential benefits, and even anecdotal evidence, indicating deep engagement and curiosity.

ImpactHigh impact

The overall tone suggests these discussions see this research as impactful, with some highlighting it as a possible game-changer in cancer treatment.

Abstract in brief

  • This study introduces a new cancer treatment strategy that combines two FDA-approved antibiotics, Doxycycline and Azithromycin, with Vitamin C to target cancer stem cells (CSCs) by disrupting their mitochondrial function.
  • The approach works by inhibiting mitochondrial protein synthesis through the antibiotics and inducing mitochondrial biogenesis via oxidative stress from Vitamin C, leading to a dramatic 90% reduction in CSC growth in breast cancer cells.
  • Using sub-antimicrobial doses helps avoid antibiotic resistance issues, and the findings suggest this combination could be a promising and innovative way to target tumor growth and improve overall health.

Top posts

Most liked on X and Bluesky
Mark
@Supertelomerase · X

@Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline (to impair mitochondrial biogenesis) killed cancer stem cells. Here it is: https://t.co/MBI2saUEWO

Sep 30, 2022 · 53 likes · 9 shares · 33 followers View post →
MitoMedicine
@MitoMedicine · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). - PubMed - NCBI https://t.co/DCDUtFH6zw

Apr 20, 2019 · 20 likes · 10 shares · 2,980 followers View post →
J
@QuantumMed3 · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). https://t.co/HYwsLzjG5V

Jan 18, 2022 · 4 likes · 3 shares · 983 followers View post →
Marek Bogacki
@documentavi · X

@questmoosa article https://t.co/ANnPo2QkN4 study https://t.co/d4fLA7329Y also • Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/PySGhaljCh grok https://t.co/CXXlCzPQKr .

Sep 28, 2025 · 3 likes · 1,420 followers View post →
Mona-Lisa
@Obamasshadow · X

@ebmpsykiatri @miraaksoys https://t.co/gQ5lwViu0A

May 17, 2020 · 2 likes · 7,570 followers View post →
Rene Sugar
@renesugar · X

@ErinSandersNP Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/oAnyLnbKld

Sep 8, 2023 · 2 likes · 3,971 followers View post →

All mentions

Marek Bogacki
@documentavi · X

@questmoosa article https://t.co/ANnPo2QkN4 study https://t.co/d4fLA7329Y also • Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/PySGhaljCh grok https://t.co/CXXlCzPQKr .

Sep 28, 2025 · 3 likes · 1,420 followers View post →
Rene Sugar
@renesugar.bsky.social · Bluesky

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) www.aging-us.com/article/1019...

May 19, 2025 · 1 share View post →
Rene Sugar
@renesugar · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/4wjOiSn0As

May 19, 2025 · 1 like · 3,971 followers View post →
Rene Sugar
@renesugar · X

@DrZeedMD Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/nJ9wHGgX2o

Mar 27, 2025 · 3,971 followers View post →
Dawn Cole
@ColeDawnu · X

RT @localhostsci: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Feb 5, 2025 · 1 share · 154 followers View post →
Ally Jonsson
@AllyJonsson · X

Triple therapy of low dose common drugs reduced cancer in 3 breast cancer cell lines by 90% Azithromycin, Doxycycline & Vitamin C Let's get the clinical trials happening! Cheaper & less toxic than typical chemotherapy & radiation! https://t.co/2HhtshIC0P

Jul 3, 2024 · 1,152 followers View post →
Van
@patternfollower · X

@AcctBannedIn321 @Blagosklonny https://t.co/ECOcVQWAPd

May 12, 2024 · 48 followers View post →
Van
@patternfollower · X

@Blagosklonny Dr. B, take a look at this paper on Cancer and Longevity protocol. Very interesting just like verapamil. https://t.co/p7LSjhTz04

May 12, 2024 · 48 followers View post →
Dr. Lora Chamberlain
@FrackingFreeIL · X

RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…

Mar 6, 2024 · 3 shares · 501 followers View post →
Good Luck
@GoodLuck_BSafe · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/nY42h05Ksz

Dec 24, 2023 · 239 followers View post →
Dammian Miller
@DammianMiller · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/NosaodxZ7B

Nov 26, 2023 · 367 followers View post →
luthfi darmawan
@luthffffi · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ... https://t.co/1syV4Io6ob

Nov 26, 2023 · 1 like · 11 followers View post →
OxS
@splusoh · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/9zASY53QnO

Nov 26, 2023 · 637 followers View post →
American Dreamer
@ARebel562 · X

RT @Orlando_uy: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating canc…

Sep 27, 2023 · 2 shares · 412 followers View post →
Orlando_uy
@Orlando_uy · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells. https://t.co/8SKUXxVjhB

Sep 27, 2023 · 1 like · 2 shares · 694 followers View post →
Rene Sugar
@renesugar · X

@ErinSandersNP Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/oAnyLnbKld

Sep 8, 2023 · 2 likes · 3,971 followers View post →
Rene Sugar
@renesugar · X

@AmandaB55744931 @Naomi_D_Harvey Someone told me their dog was given doxycycline for palliative reasons and it ended up treating their dog's cancer; dogs make their own vitamin C. eg. Doxycycline, Azithromycin and Vitamin C https://t.co/4wjOiSn0As https://t.co/CijWit6B0Z https://t.co/mtrRRt2EcH

Jan 4, 2023 · 1 like · 3,971 followers View post →
Rene Sugar
@renesugar · X

RT @renesugar: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cance…

Dec 31, 2022 · 1 share · 3,971 followers View post →
Yurii
@Yurii08720681 · X

@bhushanlab what do you think about doxycycline and azithromycin? - as synolytics, in this article the anti-cancer strategy is discussed, but anti-aging is mentioned. https://t.co/amEVBGpuUC

Oct 17, 2022 · 34 followers View post →
Vic Martinez
@truthseeker1961 · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 624 followers View post →
Slawomir
@Slawomi18369321 · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 85 followers View post →
Kevin Quirk
@KevinQuirk9 · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 228 followers View post →
Birsen
@BTUR3 · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 336 followers View post →
Carsten Erdmann
@Dr_C_Erdmann · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 87 followers View post →
SamOlivetree
@SamOlivetree · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Oct 1, 2022 · 9 shares · 123 followers View post →
Orioso de Rohars
@Orioso_Rohars · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Sep 30, 2022 · 9 shares · 416 followers View post →
Sum_1
@a_place_n_time · X

RT @Supertelomerase: @Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline…

Sep 30, 2022 · 9 shares · 1,102 followers View post →
Mark
@Supertelomerase · X

@Mangan150 I read a paper a few years ago showing high dose Vit C (to increase ROS) plus azithromycin and Doxycycline (to impair mitochondrial biogenesis) killed cancer stem cells. Here it is: https://t.co/MBI2saUEWO

Sep 30, 2022 · 53 likes · 9 shares · 33 followers View post →
Yurii
@Yurii08720681 · X

@haidut of: Doxycycline, Azithromycin and Vitamin C (DAV) the result is more than 90% https://t.co/amEVBGoX54

Sep 27, 2022 · 1 like · 34 followers View post →
LeAnne LawtonTancred
@LeAnneTancred · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells. https://t.co/HS2sV5geHg

Apr 8, 2022 · 985 followers View post →
LeAnne LawtonTancred
@LeAnneTancred · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicat… https://t.co/HS2sV5geHg

Apr 8, 2022 · 985 followers View post →
The Good Life 4 Us
@thegoodlife4us · X

RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…

Jan 18, 2022 · 3 shares · 3,644 followers View post →
Truth Seeker
@Amy21407287 · X

RT @QuantumMed3: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating can…

Jan 18, 2022 · 3 shares · 9,966 followers View post →
J
@QuantumMed3 · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). https://t.co/HYwsLzjG5V

Jan 18, 2022 · 4 likes · 3 shares · 983 followers View post →
Rene Sugar
@renesugar · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/7jXroYC0D8 "Combination of low-dose Doxycycline and Azithromycin reduces glycolysis and glycolytic reserve."

Oct 28, 2021 · 1 like · 1 share · 3,971 followers View post →
localhostscience
@localhostsci · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Sep 29, 2021 · 1 share · 34 followers View post →
AntiAgify - Science will set you free
@AntiAgify · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). Plus: "Azithromycin is an anti-aging drug that behaves as a senolytic... " https://t.co/iXOjmrMolu

Oct 4, 2020 · 2 likes · 1,352 followers View post →
Black Bird
@DopeBodhi · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) https://t.co/jYVliJIAdN

Aug 1, 2020 · 2,272 followers View post →
Black Bird
@DopeBodhi · X

@RealBrianWatt Check out https://t.co/3hn8Xfl2Ye Doxycycline, Azithromycin and Vitamin C (DAV): A Potent Combination Therapy for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs)

Jun 10, 2020 · 2,272 followers View post →
Mona-Lisa
@Obamasshadow · X

@ebmpsykiatri @miraaksoys https://t.co/gQ5lwViu0A

May 17, 2020 · 2 likes · 7,570 followers View post →
Alexander Dreyzen
@ADreyzen · X

@Blagosklonny Does this cocktail also inhibit normal stem cells proliferation? I couldn't find the answer here: https://t.co/3tleVGcSHT

Jan 14, 2020 · 605 followers View post →
Leon Yuan
@yxlearn · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). - PubMed - NCBI https://t.co/tDcHS6tYbK

Dec 9, 2019 · 232 followers View post →
Zhi Sheng
@zhishenglab · X

RT @OpenResSalford:

May 4, 2019 · 1 share · 107 followers View post →
Open Research UoS
@OpenResSalford · X

May 3, 2019 · 1 like · 1 share · 1,154 followers View post →
Women's Health News
@womens_womens · X

RT @womens_womens: Doxycycline Azithromycin and Vitamin C DAV A potent combination therapy for targeting mitochondria and eradicating cance…

Apr 22, 2019 · 1 share · 456 followers View post →
Philo
@ingridjota · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 21, 2019 · 10 shares · 258 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 21, 2019 · 10 shares · 6,546 followers View post →
L. J.
@lmj612 · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 21, 2019 · 10 shares · 1,164 followers View post →
Likepiterathome
@likepiterathome · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 21, 2019 · 10 shares · 276 followers View post →
JoaquimLamora
@JoaquimLamora · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 21, 2019 · 10 shares · 1,133 followers View post →
Mitochondrial News
@MitochondriaNe1 · X

#mitochondria Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). https://t.co/WFmSZ2jAQH via @MitochondriaNe1

Apr 21, 2019 · 1 like · 2,254 followers View post →
Marilyn Gavranovic
@MarilynGavrano5 · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 20, 2019 · 10 shares · 492 followers View post →
☀️LRstardust⭐️
@RotmeLingnoi · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 20, 2019 · 10 shares · 75 followers View post →
Adi Setyawan MD
@AdiSObGyn · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 20, 2019 · 10 shares · 353 followers View post →
Joe Gordon
@josephwgordon · X

RT @MitoMedicine: Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating ca…

Apr 20, 2019 · 10 shares · 2,111 followers View post →
MitoMedicine
@MitoMedicine · X

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). - PubMed - NCBI https://t.co/DCDUtFH6zw

Apr 20, 2019 · 20 likes · 10 shares · 2,980 followers View post →
Women's Health News
@womens_womens · X

Doxycycline Azithromycin and Vitamin C DAV A potent combination therapy for targeting mitochondria and eradicating cancer stem cells CSCs.: Here we devised a new strategy for eradicating cancer stem cells CSCs via a "syntheticmetabolic" approach… https://t.co/RsWdy7pspk

Apr 20, 2019 · 1 share · 456 followers View post →