Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.

Murali K Matta, Robbert Zusterzeel, Nageswara R Pilli, Vikram Patel, Donna A Volpe, Jeffry Florian, Luke Oh, Edward Bashaw, Issam Zineh, Carlos Sanabria, Sarah Kemp, Anthony Godfrey, Steven Adah, Sergio Coelho, Jian Wang

June 2019 JAMA

Synopsis of Social media discussions

Several posts highlight the alarming absorption rates of sunscreen ingredients like oxybenzone, with users urging others to reconsider their sunscreen choices. Phrases such as 'Stop using this sunscreen' and 'it's absorbing into your body' indicate a sense of urgency and concern. The tone reflects a mixture of alarm and a call for further investigation, underscoring the weight many place on the study's findings regarding potential health risks.

A
Agreement
 Moderate agreement

The majority of discussions express concern regarding the safety implications of sunscreens absorbing into the body, with many reinforcing the need for caution.

I
Interest
 High level of interest

There is a high level of curiosity about the study and its findings, reflecting its relevance to public health.

E
Engagement
 High engagement

Participants show deep engagement by referencing specifics from the trial, indicating a clear understanding of its methodologies and outcomes.

I
Impact
 High level of impact

Many users perceive this research as having significant implications for sunscreen use and public health discussions.

Social Mentions

YouTube

5 Videos

Bluesky

1 Posts

Facebook

69 Posts

Twitter

81 Posts

Blogs

27 Articles

News

431 Articles

Reddit

8 Posts

Metrics

Video Views

80,606

Total Likes

4,650

Extended Reach

1,193,966

Social Features

622

Timeline: Posts about article

Top Social Media Posts

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  • e
    @jiranma (Twitter)

    cc: @drdrayzday https://t.co/HXWtvfy7hX
    view full post

    October 9, 2025

  • Tim Spector MD (Prof)
    @timspector (Twitter)

    If you want a good explanation of why wearing SPF creams in winter is rubbish advice - listen to @LizEarleMe https://t.co/SvYaTX7j5F
    view full post

    October 8, 2025

    8

  • Scleroderma Warrior
    @SclerodermaWar (Twitter)

    Stop Using This Sunscreen — It’s Absorbing Into Your Body | Dr. Mandell https://t.co/oIZySyNCIH via @YouTube
    view full post

    August 25, 2025

  • confidential
    @confidential16 (Twitter)

    https://t.co/aAHUjcslhK
    view full post

    August 21, 2025

  • cindi c
    @cindicheever (Twitter)

    Stop Using This Sunscreen — It’s Absorbing Into Your Body | Dr. Mandell https://t.co/nG4H2raY3X via @YouTube
    view full post

    August 21, 2025

    1

  • Sean B Flanagan
    @SeanBFlanagan (Twitter)

    RT @SeanBFlanagan: @BellaWallerstei @RealJermWarfare Dr Mandell: “Stop using sunscreen - it’s absorbing into your body.” https://t.co/zmFt6…
    view full post

    August 21, 2025

    1

  • Sean B Flanagan
    @SeanBFlanagan (Twitter)

    @BellaWallerstei @RealJermWarfare Dr Mandell: “Stop using sunscreen - it’s absorbing into your body.” https://t.co/zmFt6TeAmT
    view full post

    August 21, 2025

    1

  • Hugo
    @nonviolence.bsky.social (Bluesky)

    Don't risk your health until we know more. Use
    view full post

    August 5, 2025

    1

  • Lars
    @Lars_Hansen_86 (Twitter)

    Efter blot 1 dags brug af solcreme så har man hormonforstyrrende kemikalier, Oxybenzone, niveauer over de maksimale anbefalede værdier, i sit blod. Så hvis man gerne vil have børnebørn, så er det en god ide at lade være med at give sin børn solcreme på! https://t.co/trmC8jj7hD
    view full post

    July 15, 2025

  • EKa.Systemanalyse
    @KochID19 (Twitter)

    @littlewisehen @BaumleSandra @olivergorus Fundiertes Wissen™ und @littlewisehen - der Witz war wirklich gut
    view full post

    May 13, 2025

    9

  • Monarchia Costituzionale Italia
    @MonarchiaItalia (Twitter)

    @Bluefidel47 O lei non sa leggere oppure le fa comodo gettare allarmismo nella popolazione! Impari a leggere e non riporti solamente ciò che le fa comodo. https://t.co/fkBXnuiMiC “… Questi risultati non indicano che le persone dovrebbero astenersi dall'uso della protezione solare.”
    view full post

    July 23, 2023

  • alephh
    @alephh (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients (randomized clinical trial) – Systemic concentrations greater than 0.5 ng/mL were reached for all 4 products after 4 applications on day 1. https://t.co/629Et3onJB
    view full post

    June 14, 2023

  • Sepi Daddy Cool
    @CoolSepi (Twitter)

    RT @OssiViljakainen: @ThomasSndbk Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active…
    view full post

    June 25, 2022

    1

  • Ossi Viljakainen
    @OssiViljakainen (Twitter)

    @ThomasSndbk Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active IngredientsA Randomized Clinical Trial. https://t.co/jeGzYdmWVf Benzophenone-3 (BP-3) Factsheet https://t.co/dIX8bDt6rb
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    June 25, 2022

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    1

  • The Powers That Be
    @JaradBryant (Twitter)

    @GGrucilla A friends child was told he needed an inhaler She said no Now 28 he doesnt need 1 The sun is very good Flu season is essentially low Vitamin D season Vitamin D is blocked by sunblock Zinc cream can work Carrot juice could work Astaxanthin is good https://t.co/qlMfZJ4YZl
    view full post

    March 26, 2022

  • 江浦正秀
    @euramasahide (Twitter)

    「日焼け止め」を毎日塗って大丈夫？ アメリカ政府機関が指摘した“あるリスク” （笹井恵里子） 【文春オンライン】 https://t.co/1WpE03MSj4 https://t.co/DfiNYSBUgJ https://t.co/Zeo3RqgOS1
    view full post

    July 26, 2020

  • POPLINE
    @POPLINE_org (Twitter)

    RT @EurekaMag: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Crit…
    view full post

    April 17, 2020

    3

  • Science Alerts
    @Science_Alerts (Twitter)

    RT @EurekaMag: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Crit…
    view full post

    March 18, 2020

    3

  • POPLINE
    @POPLINE_org (Twitter)

    RT @EurekaMag: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Crit…
    view full post

    March 18, 2020

    3

  • EurekaMag
    @EurekaMag (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Critical Appraisal https://t.co/DaxHHlJM5D
    view full post

    March 18, 2020

    3

  • David Strauss
    @davidgstrauss (Twitter)

    Proud to announce that our article, “Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients”, appears in this year’s @Altmetric Top 100 as #56. See the full Top 100 list here: https://t.co/afeR8zJG3a. #AltmetricTop100
    view full post

    December 20, 2019

    2

  • KristopherMaday PA-C
    @PA_Maday (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/srQJ1yGozi https://t.co/noGzxW84xZ
    view full post

    December 18, 2019

  • Nathan Letts, PhD
    @Sciguy999 (Twitter)

    @altmetric #56 of 100 Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/rHaX47h7jX & https://t.co/W6RICWpOkn #sunscreen #cancer @JAMA_current
    view full post

    December 17, 2019

  • Reiner 
    @erlesen (Twitter)

    RT @erlesen: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t…
    view full post

    August 19, 2019

    3

  • Bruce Booth
    @LifeSciVC (Twitter)

    While sun bathing this summer.... Systemic concentrations of sunscreen “actives” are higher than FDA guidance. Safety risk? Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Actives: Clinical Trial https://t.co/v4kaht0Kuu
    view full post

    August 15, 2019

    7


  • @do_maple (Twitter)

    RT @chemistscorner: Sunscreen actives penetrate through skin - More testing may be required - Effect of Sunscreen Application Under Maximal…
    view full post

    June 20, 2019

    2

  • Salim Ali
    @SyntheticAli (Twitter)

    @brooklynmarie This write-up is a bit hyperbolic and clickbait-y. The only reaction this warrants is: "Mhmm, that's interesting." From the article: "These results do not indicate that individuals should refrain from the use of sunscreen." (DOI: 10.1001/jama.2019.5586)
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    June 16, 2019

    2

  • Cyrille Laurent
    @CyrilleLaurent2 (Twitter)


    view full post

    June 9, 2019

  • JAMA
    @JAMA_current (Twitter)

    RT @chrishendel: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of #Sunscreen Active Ingredients via…
    view full post

    June 8, 2019

    2

  • Dr. Linda Makuta DDS
    @lindamakuta (Twitter)

    Effect of sunscreen application under maximal use conditions on plasma concentration of sunscreen active ingredients https://t.co/sa3ssjfoiQ
    view full post

    June 6, 2019

  • お か ゆ
    @sksztnk (Twitter)

    皮膚から思ったより血中に入る話。：Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/UlpGnxBPBw
    view full post

    June 4, 2019

    4

  • ex-caregiver ✝️
    @stevecripe57 (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/h2FoZRcYch via @practiceupdate
    view full post

    June 2, 2019

  • #BeautyRecap
    @BeautyRecap (Twitter)

    Effect of sunscreen application under maximal use conditions on plasma concentration of sunscreen active ingredients https://t.co/CcXkEQL7MB
    view full post

    May 30, 2019

    1

  • Briony Turner FRSA
    @turner_briony (Twitter)

    RT @polsiewski: Troubling results - @IndoorChem Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sun…
    view full post

    May 19, 2019

    2

  • Paula Olsiewski
    @polsiewski (Twitter)

    Troubling results - @IndoorChem Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/YaZBmEXFHQ
    view full post

    May 19, 2019

    3

    2

  • Dr Michael Barakate
    @michaelbarakate (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/RWaXQZ8HY3
    view full post

    May 18, 2019

  • M David
    @mirund (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/LHOm636iZe
    view full post

    May 18, 2019

  • the paper link
    @the_paper_link (Twitter)

    [trend] up+1: *Matta MK* et al (JAMA) **Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.** https://t.co/5Z1Th2dL8R
    view full post

    May 17, 2019

  • Sabina Akther
    @yesmin390 (Twitter)

    RT @barryhardy: Effect of #Sunscreen Application Under Maximal Use Conditions on #Plasma Concentration of Sunscreen Active Ingredients - sy…
    view full post

    May 15, 2019

    5

  • Paa Qwesi
    @AmponsahOrtin (Twitter)

    RT @barryhardy: Effect of #Sunscreen Application Under Maximal Use Conditions on #Plasma Concentration of Sunscreen Active Ingredients - sy…
    view full post

    May 14, 2019

    5

  • the paper link
    @the_paper_link (Twitter)

    [trend] up+1: *Matta MK* et al (JAMA) **Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.** https://t.co/5Z1Th2dL8R
    view full post

    May 14, 2019

  • KC Maiyo
    @kcmaiyo (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active IngredientsA Randomized Clinical Trial. https://t.co/cT3cg6v1IF
    view full post

    May 12, 2019

  • Dr. Deepti Sadhwani
    @deeptisadhwani (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/Vu9KWRYhQq
    view full post

    May 12, 2019

  • hesham kamel
    @heshamk81740629 (Twitter)

    RT @barryhardy: Effect of #Sunscreen Application Under Maximal Use Conditions on #Plasma Concentration of Sunscreen Active Ingredients - sy…
    view full post

    May 12, 2019

    5

  • ACAFARMUR
    @acafarmur (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/1rU3SzDfu4
    view full post

    May 12, 2019

  • José Mª Gª Quintana
    @jose_g_quintana (Twitter)

    RT @emma_beltran: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A R…
    view full post

    May 12, 2019

    1

  • Luis Rguez. Padial
    @luisrpadial (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/oy2cXmrxd7
    view full post

    May 11, 2019

  • Josep Vidal-Alaball MD, PhD, MPH
    @jvalaball (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | #publichealth https://t.co/ehCCOyyUHD
    view full post

    May 11, 2019

    1

  • IGOT7_RT#6
    @yooka6_igot7 (Twitter)

    RT @barryhardy: Effect of #Sunscreen Application Under Maximal Use Conditions on #Plasma Concentration of Sunscreen Active Ingredients - sy…
    view full post

    May 9, 2019

    5

  • HealthyBuilds
    @HealthyBuilds (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/3sCmjMePA5
    view full post

    May 9, 2019

  • HealthyBuilds West Palm
    @NanoSafe1 (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/lewfmAlzNK
    view full post

    May 9, 2019

  • The Eco Well
    @TheEcoWell (Twitter)

    RT @chemistscorner: Sunscreen actives penetrate through skin - More testing may be required - Effect of Sunscreen Application Under Maximal…
    view full post

    May 9, 2019

    2

  • Dr Rasha Abdelsalam Elshenawy
    @salam_rasha (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients A Randomized Clinical Trial https://t.co/TXAh0bH4AI @accpambuprn https://t.co/NFqHjqHDKM
    view full post

    May 8, 2019

  • Holly Morello, FNTP
    @NourishingHolly (Twitter)

    More about the Randomized Clinical Trial of the Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients shared by Dr. Rhonda Patrick of FoundMyFitness... https://t.co/Ws0SLDYCiM
    view full post

    May 8, 2019

  • J. L. Weimer
    @JLsPerspective (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network ⁦⁦@foundmyfitness⁩ is a genius #science https://t.co/XDeMzTHapa
    view full post

    May 8, 2019

  • Joseph KAMTCHUM TATUENE
    @JTatuene (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/wR4X6eA3WT
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    May 8, 2019

  • Tom Riley
    @GrapeBelt (Twitter)

    RT @DoctorTro:
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    May 8, 2019

    12

  • Web on-line
    @reel62313077 (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network #SmartNews https://t.co/NhWgCdbmMH
    view full post

    May 8, 2019

  • Matt Price
    @MRPsci (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial https://t.co/ocxJ282zOj
    view full post

    May 8, 2019

  • 小嶋 慎二＠community pharmacist
    @kojima_aponet (Twitter)

    【JAMA】 Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients A Randomized Clinical Trial https://t.co/wMxmphAqBw
    view full post

    May 8, 2019

    6

  • Amy Kelly
    @amkelly14748 (Twitter)

    RT @erlesen: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t…
    view full post

    May 7, 2019

    3

  • Reiner 
    @erlesen (Twitter)

    RT @erlesen: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t…
    view full post

    May 7, 2019

    3

  • Phil Hulbig
    @phulbig2 (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/Co6jdbmJ4b
    view full post

    May 7, 2019

  • ActivatedNutJob
    @ActivatedNutJob (Twitter)

    RT @DoctorTro:
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    May 7, 2019

    12

  • Clint Muench
    @CFboneDoc (Twitter)

    RT @DoctorTro:
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    May 7, 2019

    12

  • Renato Toth
    @renatomolinat (Twitter)

    RT @DoctorTro:
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    May 7, 2019

    12

  • Steven Gundry MD
    @DrGundry (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network. Sunscreen ingredients reach toxic levels in us https://t.co/IBUg1y15rd
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    May 7, 2019

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  • ACAFARMUR
    @acafarmur (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/1rU3SzDfu4
    view full post

    May 7, 2019

  • meddle with emergent complexity at your peril
    @prb2o1o (Twitter)

    RT @DoctorTro:
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    May 7, 2019

    12

  • A Man on a Fast
    @manonafast (Twitter)

    RT @DoctorTro:
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    May 7, 2019

    12

  • DoctorTro
    @DoctorTro (Twitter)


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    May 7, 2019

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    12

  • Jason H. Moore, PhD
    @moorejh (Twitter)

    Effect of #Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial - JAMA https://t.co/zrJ3lpVIiX #skin #toxicology #sunburn #dermatology
    view full post

    May 7, 2019

    2

  • Barry Hardy
    @barryhardy (Twitter)

    Effect of #Sunscreen Application Under Maximal Use Conditions on #Plasma Concentration of Sunscreen Active Ingredients - systemic #absorption of ingredients supports need for further studies involving #assessment #safety #design #systemic #toxicology https://t.co/KImYHnJb4b
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    May 7, 2019

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    5

  • AndreaPMM #TodoMi6%aFondoSolidario. Reparto TriP
    @andrea_pmm (Twitter)

    RT @NutrSinMarcas: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A…
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    May 7, 2019

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  • Vicente Pallares
    @vic_pallares (Twitter)


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    May 7, 2019

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  • Gac Ciencia Forense
    @GacetaCienForen (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients : https://t.co/pvcbzT1X3V
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    May 6, 2019

  • DraCeciCastilloLancellotti
    @NutrSinMarcas (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/7k73zQCnUL
    view full post

    May 6, 2019

    1

  • Kelly A. Hogan Ph.D.
    @Loose_Lab_Rat (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/B2KTFUQOm7
    view full post

    May 6, 2019

  • Reiner 
    @erlesen (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients https://t.co/dUXYTcJ2QH Sunscreen Ingredients Are Absorbed Into Your Blood❗ https://t.co/eSYaZOwSYI Some Types Of Sunscreen Do More Harm Than Good❗
    view full post

    May 6, 2019

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    3

  • Harvey Fishman, MD PhD
    @drfishman (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA | JAMA Network https://t.co/xhulmmDpix
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    May 6, 2019

  • Seth Trueger
    @MDaware (Twitter)

    RT @chrishendel: Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of #Sunscreen Active Ingredients via…
    view full post

    May 6, 2019

    2

  • Chris Hendel
    @chrishendel (Twitter)

    Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of #Sunscreen Active Ingredients via @JAMA_current today https://t.co/ujnsjsqZXr https://t.co/5ePO4EmPmT https://t.co/0M1n7GUzWu
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    May 6, 2019

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Abstract Synopsis

  • The study investigates the systemic absorption of active ingredients in four commercial sunscreens—avobenzone, oxybenzone, octocrylene, and ecamsule—under conditions of maximal application, as required by FDA guidelines for safety evaluation.
  • 24 healthy volunteers applied two milligrams of sunscreen per square centimeter over 75% of their body four times daily for four days, with blood samples collected over seven days to analyze plasma concentrations of the sunscreen ingredients.
  • Results indicated significant absorption of avobenzone and oxybenzone, with geometric mean maximum plasma concentrations reaching up to 40 ng/mL for avobenzone and around 2096 ng/mL for oxybenzone, raising potential safety considerations for these common sunscreen elements.