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This collection of discussions demonstrates a high level of engagement with the nuances of ApoB testing, including debates about its superiority over LDL-C and non-HDL-C, and references to emerging research and laboratory innovations. Terms like 'game changer', 'powerful platform', and detailed mentions of clinical trials convey enthusiasm and recognition of its potential impact in cardiovascular risk management.
Most discussions support the significance of ApoB as a biomarker for cardiovascular risk and emphasize its potential to improve prevention strategies.
The extensive exchange of detailed scientific insights, debates on testing protocols, and mentions of advanced imaging and biomarkers reflect high curiosity and engagement with the subject.
Many posts involve technical analyses, references to studies, and discussions about clinical applications, indicating deep involvement and complex exchanges.
The discussions highlight how incorporating ApoB measurements could revolutionize risk assessment and treatment, suggesting a profound influence on clinical practice and guidelines.
Children with COVID or MIS-C show major metabolic changes, like high triglycerides and inflammation, that mirror severe adult COVID infection. These shifts could raise long-term heart risks, especially after MIS-C. More follow-up is urgently needed. buff.ly/f4nIdfO #medsky #pedsky
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The academic debates arnd saturated fat have largely questioned whether they're as 'bad' as once thought, given the limited association w CVD in cohort studies assessing self reported intakes in relation to risk (despite controlled feeding trials clearly showing a linear relationship w LDL/ApoB).
I'm a complete stan for retatrutide as a drug and here's another reason. Not only does it lower LDL and triglycerides at statin and fibrate levels...but it lowers all these other remnant cholesterols. It lowers ApoCIII, ApoB, & ANGPTL3/8, it changes FGF21. It does the work of multiple drugs alone!
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With everything else equal, your chances of dying from heart disease are the highest. However, recent insights have highlighted the importance of apoB, a protein that plays a crucial role in cholesterol transport and…
This video critically analyzes Dr. Eric Berg's health advice. It addresses serious aspects of the misinformation he presents and the potential adverse effects on health. This analysis aims to debunk false claims in the…
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RT @Lupin_Ai_Coder: AI influencers are printing money right now. They post 24/7. Never burn out. Always look perfect. Here's how you can…
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Enlicitide, inhibidor PCSK9 VO, reduce en más del 50% las LDL, apoB y Lp(a) en pacientes con enfermedad CV aterosclerótica e hipercolesterolemia familiar heterocigota firstwordpharma.com/story/6519517
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Creators are already using APOB to:
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@AlexJLeaf ...leads to retention. And why we see it in specific areas, is ApoB "avoiding" places to retain, what makes the "leak" possible? Of course, you don't have to answer those questions, but I hope you can see where I'm going with this.
@AlexJLeaf I suppose this is where we don't see things the same way exactly. Would you then make the argument that ApoB retention occurs by mere presence? If not, what causes the retention? If it does, is there any scenario in which presence doesn't lead to retention or all ApoB presence...
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But here’s the truth
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RT @HaniaAi12: The Next Era of Brand Influence is Here
RT @HaniaAi12: The Next Era of Brand Influence is Here
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RT @CBallantyneMD: Exciting new option to lower #apoB #ldl #nonHdlc and Lp(a) @nationallipid @ASPCardio @CMHC_CME @society_eas @BCMHeart @…
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RT @HaniaAi12: The Next Era of Brand Influence is Here
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RT @HaniaAi12: The Next Era of Brand Influence is Here
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@RapaNews @LinusPeters if high LDL and APOB become a problem (is high), at 6MG/week, what is the thinking on what/how current best thought protocols suggest to adjust dosing amount and schedule, or other?
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RT @maxlugavere: Got some new labs! ApoB: 86 mg/dL HDL: 53 mg/dL Triglycerides: 79 mg/dL Total T: 747 ng/dL Homocysteine is a bit high (1…
@Lupin_Ai_Coder Apob is best
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4/4Use the Image to Video feature to bring your pictures to life based on your ideas. You can also choose from different Al voices to make your creations speak. Discover even more creative Al tools inside APOB. Start now and see what you can create: https://t.co/bP0EDbLbM6 https://t.co/Jt0ItFw8dJ
2/4 With the Complete Set option, one click gives you: Artistic portraits like retro, cyberpunk & more Professional LinkedIn headshots from surfing to gym bikinis Try it here: https://t.co/bP0EDbLbM6 https://t.co/3EbjexYol7
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1/4 Sign up on APOB and hit "Create Portrait Model" to design your own Al influencer. Just pick a style, click Generate, and watch the magic happen! https://t.co/b2b1dde10n
Want to make money online while having fun?
RT @Lupin_Ai_Coder: AI influencers are printing money right now. They post 24/7. Never burn out. Always look perfect. Here's how you can…
4/4Use the Image to Video feature to bring your pictures to life based on your ideas. You can also choose from different Al voices to make your creations speak. Discover even more creative Al tools inside APOB. Start now and see what you can create: https://t.co/bP0EDbLbM6 https://t.co/zSlmtccAQo
RT @CBallantyneMD: Exciting new option to lower #apoB #ldl #nonHdlc and Lp(a) @nationallipid @ASPCardio @CMHC_CME @society_eas @BCMHeart @…
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RT @Lupin_Ai_Coder: AI influencers are printing money right now. They post 24/7. Never burn out. Always look perfect. Here's how you can…
RT @Lupin_Ai_Coder: AI influencers are printing money right now. They post 24/7. Never burn out. Always look perfect. Here's how you can…
1/4 Sign up on APOB and hit "Create Portrait Model" to design your own Al influencer. Just pick a style, click Generate, and watch the magic happen! https://t.co/DIOrZBTNk4
RT @CBallantyneMD: Exciting new option to lower #apoB #ldl #nonHdlc and Lp(a) @nationallipid @ASPCardio @CMHC_CME @society_eas @BCMHeart @…
LDL-C isn’t the whole picture. Other factors like LDL particles, ApoB, Lp(a), non-HDL-C, and low HDL-C can contribute to residual ASCVD risk. Learn about each of these factors: www.expectmoreforldl.com/ldl-c-and-be...
Advanced tests like ApoB and cardiac CT scans were highlighted as superior risk assessment tools. Some argue these should be more widely adopted to provide clearer, individualized insights beyond standard cholesterol panels.
Just saw this. Good review on uses of apoB testing. In my view, apoB testing has a broader role than envisioned here. jamesstein18.substack.com/p/when-lipop...
Thoughtful, provocative editorial. Some fair points. Respectfully disagree with apoB/CAC examples. IMO evidence base (including health economics) for these support broader use and are incorporated in some guidelines (apoB: EAS/ESC, CCS, NLA statement) #cardiosky bsky.app/profile/jame...
But @lukeoconnor.bsky.social's group showed that burden tests seem to be better at picking out the "right" genes (e.g., APOB for LDL cholesterol, MSH2, BRCA1, BRCA2 for cancer). What gives? Do these tests "converge"? Or are burden tests "better"? www.nature.com/articles/s41... 3/n
However, engineered ApoB can be used for drug delivery, and in a recent study, a modified form of the ApoB protein was found to be capable of crossing the BBB in fruit flies (drosophila). pmc.ncbi.nlm.nih.gov/articles/PMC...
Responding to Mycotropic @mycotropic@beige.party Apolipoprotein B (ApoB) itself does not normally cross the blood-brain barrier (BBB) in significant amounts, as circulating ApoB-containing lipids are prevented from entering the brain.
Small-interfering RNA olpasiran reduced lipoprotein(a)–apolipoprotein B particles by >95% with minimal rise in non–Lp(a)-apoB, lowering total apoB concentration in patients with cardiovascular disease. ja.ma/4hTt1u1
Soo ... i did actually story board this. You figure out limitations real quick. #apob #aiartstory
Lipoprotein(a) - The Overlooked Lipoprotein That Drives Heart Disease. This inherited particle may explain why some people develop heart disease despite excellent cholesterol levels. For my latest on Substack, go to jamesstein18.substack.com/p/part-2-lpa...
Up next metabolic markers and RAAS system: insulin, C-peptide, renin, angiotensinogen, and aldosterone Calcium, phosphate, parathyroid hormone, vitamin D, ApoB, APoC3, NT-BNP, Also "serum large-scale proteomic analysis will be performed to assess changes in protein metabolism" Almost done!
Newborn screening using LDL-C and apolipoprotein B, followed by genetic testing, may substantially improve early diagnosis of familial hypercholesterolemia, a treatable genetic condition. ja.ma/4qoSn6C
Interesting snippet in the Saint-Cloud report from @seenthestars.bsky.social in the Racing Post. Presumably, Wildenstein told O’Brien that he was taking all his horses away even though APOB didn’t train any for him.
When you see high vs low satfat intake not associating w CVD, that could be bc there is no relationship,or it could be bc people eating low satfat eat more of something that is equally risky for CVD (thru ApoB or non-ApoB-mediated risk). The latter is what the thinking in the field is currently
The academic debates arnd saturated fat have largely questioned whether they're as 'bad' as once thought, given the limited association w CVD in cohort studies assessing self reported intakes in relation to risk (despite controlled feeding trials clearly showing a linear relationship w LDL/ApoB).
How should ApoB and Lp(a) be used as core measures to assess cardiovascular risk? Join experts Allan Sniderman, George Thanassoulis and Michael Pencina as they unpack the power of these biomarkers – and what they mean for prevention strategies. Listen now
An Early View: A study of 133 children with suspected dyslipidemia in Türkiye used targeted NGS to explore the genetic basis of #pediatric lipid disorders. Pathogenic variants were seen in 17% of cases, most often in LDLR, with novel variants found in LDLRAP1 and APOB.
Both isoforms of Drosophila ApoLpp (ApoB) cross the blood-brain barrier in adults https://pubmed.ncbi.nlm.nih.gov/41099152/
Both isoforms of Drosophila ApoLpp (ApoB) cross the blood-brain barrier in adults https://pubmed.ncbi.nlm.nih.gov/41099152/
So, patients with high Lp(a), OxPL-apoB & AA levels MAY benefit from early aspirin initiation. Small sample, low power, single facility. But indicative & hypotheses worth further study.
The Truth on Coconut Oil Super Food or Heart Health Hazard? Does it raise cholesterol? ApoB? What about the MCTs?! full video: https://youtu.be/Pbn_lfOv9_Q
Both isoforms of Drosophila ApoLpp (ApoB) cross the blood-brain barrier in adults #Drosophila
OUTCOME METRIC: Biomarker Delta Quarter-over-quarter change in ApoB, HbA1c, ALT Target: ApoB <80 mg/dL, HbA1c <5.5%, ALT <25 U/L Lives in: lab panel export Fix the system. Capacity decides.
PROTOCOL: 1) Run ApoB, HbA1c, ALT quarterly. 2) Cut supplements not prescribed for deficiency. 3) Reallocate budget to food, sleep, training that move those numbers.
Your supplements are stealing capacity. Trade five pills for three numbers you can trust. ApoB for lipids. HbA1c for glucose. ALT for liver stress. Biomarkers expose what pills mask.
In the UK Biobank (10 traits), ML/DL models outperformed additive PGSs for traits known to show dominance - including lipoprotein(a), alkaline phosphatase, and ApoB - but not for height (no dominance).
Warning signs nobody talks about: • Family history of heart disease • Elevated ApoB (>80 mg/dL) • Low HDL (<50 mg/dL) • Chronic inflammation • Erectile dysfunction in men • Shortness of breath during simple activities
5 life-saving blood tests you must know, according to a US doctor | – The Times of India Regular health checkups are crucial for preventing chronic illnesses. Dr. Rocio Salas-Whalen highlights five life-saving blood tests: Lp(a) for heart disease risk, ApoB for assessing LDL particle impact, ApoE…
ApoB is the main scaffolding protein found in all very low-density lipoprotein (VLDL) particles. We found that, through its sequestration of the lipolytic activator ABHD5/CGI-58, I148M causes a shift in cellular lipid composition that causes reduced membrane fluidity... Thread
However, it has proven challenging to elucidate the function of the wild-type protein and what goes awry with I148M to cause hepatic triglyceride (TG) accumulation. Here, my colleagues and I show that liver cells expressing endogenous I148M have impaired secretion of ApoB... Thread
LDL cholesterol doesn’t just affect your heart – it shapes your healthspan. Elevated ApoB levels predict earlier mortality, even in people without heart disease. Longevity Direct includes a full lipid panel in every protocol. https://longevity.direct
That’s terrifying.
What is LDL-P? LDL particles? #ApoB #LDL #particles
Is ApoB the same as LDL-Cholesterol? #ApoB #LDL #cholesterol
Study of 53 healthy adults over 12 weeks: keto (<8% carbs) increased LDL cholesterol & apoB and reduced Bifidobacteria, despite fat loss. Low-sugar diet lowered LDL with no gut harm. Keto may have trade-offs. #ketodieet #keto #Heart #TheLolgic #UK #LDL
Heart Doctor LDL is not bad? What? #cholesterol #LDL #ApoB
The discussion highlighted that bacterial presence might be a symptom, not the root cause. Many pointed to established risk factors like chronic inflammation, high ApoB levels, and insulin resistance as primary drivers of heart disease. #Cardiology 3/6
Number one way to prevent heart disease? #no1 #top1 #heartdisease #apob #ldl
Fish may nudge HDL, but the main driver of heart disease risk is LDL/Apob Plants objectively lower that while animal fats raise it “Is it the 95% dietary plants that’s helping all of those pockets of centenarians stay alive? No! Gotta be their penchant for sea animals rather than algae pills”
• start prevention earlier (than current guidelines suggest) • measure apoB Editorial by Angela Pirillo and Alberico Catapano #cardiosky academic.oup.com/eurheartj/ad...
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…the Arapaho’s territory? You might want to get an ApoB test to find out if there’s any atherosclerotic occlusion of those pencil-lead-thin cerebral arteries. That was pretty straightforward reading…
A review of 36 trials finds eating almonds improves ApoB and the ApoB:ApoA ratio—markers of heart disease risk—and lowers LDL and total cholesterol.
"This study suggests that ApoB is a more accurate marker for cardiovascular risk than LDL-P when discordant, as marked by ApoB levels in excess of LDL-P." Analysis of UK Biobank data by Elizabeth Epstein, et al. #cardiosky pubmed.ncbi.nlm.nih.gov/40887080/
CAC score 14 is the 84th %tile for 55yo woman! Calcified plaque is late stage plaque, she likely has non calcified plaque as well (not captured by CAC) amenable to regression if treated now. Given young age, has lot of life yrs at risk. Would treat with statin, aim for LDLC<70 & apoB<70. Check Lp(a)
Merck’s oral PCSK9 inhibitor, enlicitide decanoate, met all primary and key secondary endpoints in the Phase 3 CORALreef Lipids trial—showing meaningful reductions in LDL-C, non-HDL-C, ApoB & Lp(a), with a favorable safety profile. #Cholesterol www.merck.com/news/mercks-...
In such a case there’s discordance between apoB and LDL-P. Likely the LDL-P is a false positive. The apoB, LDLc and Non-HDL-C are all concordant and thus believable.
Thanks for all your great teaching. Is the LDL particle# out of whack if 1600 nmol/l when TC 151, LDL 80, HDL 60, TG 40, apoB 66mg/dL and LP(a) <10
"Understanding the Lipid Panel" - next are insights on Non-HDL-C which refers (1) to the mass (weight) in mg of cholesterol within all of the apoB-containing lipoproteins per dL or (2) the number (in mmols) of cholesterol molecules in all the apoB-particles per L.
The findings suggest the LDL-C/ApoB ratio is an independent, easily calculated marker that can enhance risk stratification and guide personalized treatment strategies for patients after PCI, beyond traditional lipid measures.
After propensity score matching, the low LDL-C/ApoB ratio group showed a significantly higher risk of major adverse cardiac events (MACE) over 3 years. Notably, this predictive value held true even when accounting for other atherogenic lipoproteins.
This study analyzed 1,682 patients who underwent percutaneous coronary intervention (PCI), dividing them into two groups based on their pre-treatment LDL-C/ApoB ratio (< 1.2 vs. ≥ 1.2).
Discover the power of the LDL-C/ApoB ratio - a game-changing predictor of heart health after PCI. This simple metric reveals hidden risks, empowering doctors to personalize care and patie...
Doctor Reveals: My FULL Bloodwork on Statins (+ side effects etc) How I cut my Cholesterol, ApoB and Triglycerides in half + Insulin Resistance, inflammation, weight loss etc etc Full video: https://youtu.be/sdtPcw69E4w
Do you need an ApoB to ApoA1 ratio? Do you need homocysteine, oxidized LDL or any other metrics? #ApoB #LDL #cholesterol
The target is the brain, but authors were treating systemically with an ApoB conjugate able to cross the blood brain barrier (authors claim). What authors do NOT show is whether there was skipping of the target exon (APP exon 15). They only show downstream effects on protein levels.
Completely eliminate heart disease? #heartdisease #apoB #ldl #cholesterol
That is a big reason why these risk calculators are useless. Base your risk on causal risk factors BP, apoB, Lp(a), smoking history and noncausal risk markers
4. Full blood panels with Function Health They test 100+ biomarkers, explain results in plain English, and give clear action steps. It’s how I learned my LDL cholesterol and ApoB are high, and exactly how to fix it.
Normal cholesterol ≠ no risk. ApoB & Lp(a) can reveal hidden heart danger — but only if you see the whole picture. Here’s how we combine them with guideline-based risk assessment to stop heart disease before it starts. precisionhealthreports.com/apob-and-lpa...
What's the difference between LDL and apoB? Which one is better? Which one should you check? What is apoB? What is LDL cholesterol?
Does the triglyceride to HDL ratio really matter? Is it better than LDL-C or apoB?
After creating your model: 1. Give it a name 2. And with that name create an Instagram account 3. Create multiple images with Apob AI and post them on your account to get followers
Big news! APOB AI has just launched the Talking Avatar feature! We’re continuously evolving—more exciting updates are on the way. Give it a try now and bring your ideas to life! app.apob.ai?via=future-s...
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it's aliiiiiiiiiiiiive!
Perhaps but it will be many years before we have any tests of HDL function. So we must continue to put attention on lowering apoB concentration
New in JLR press: "Human hepatoma Huh-7 cell culture models deficient in apolipoprotein B secretion." Learn more: www.jlr.org/article/S002...
Track for longevity
Amazing editorial by Sniderman et al - sadly firewalled - "Incorporating apoB & Lp(a) into routine clinical care will improve assessment of CV risk & will radically simplify RX —and therefore radically improve—the capacity of all caregivers globally to prevent CVD. doi.org/10.1093/eurh...
Important paper puts to rest those jumping on the VLDL/remnant bandwagon at the expense of ignoring LDLs. Please simply order apoB, a one-time Lp(a) & then lower it. The Rx that lower apoB lowers remnant-P & LDL-P (lower aggressively if Lp(a) is present. academic.oup.com/eurheartj/ar...
We've used WheresWalker to map our newly discovered #darkyolk zebrafish mutants which have defects in #ApoB-lipoprotein metabolism. We map zion to slc3a2a, a heterodimeric amino acid transporter, and find that several SLC3a2/SLC7s are associated with ApoB phenotypes in humans.
Apolipoprotein B-48 is a truncated form of apolipoprotein B-100 (consists of 48% of the ApoB-100 protein. ApoB-48 is produced by intestinal enterocytes while ApoB-100 is produced by hepatocytes.
Creb3l3 loss = lipid overload in the gut
#ESCTVToday - Konstantinos Koskinas reviews key points for lipid testing in cardiovascular risk assessment — including fasting status, high triglycerides, and diabetes. He also explains how to interpret results after acute events and when to consider ApoB, non-HDL-C & Lp(a). ow.ly/W4wv50WnKEr
ApoB: Der entscheidende Marker zur Reduzierung des Herzinfarktrisikos https://dasgeld.co/posts/DA07F015-143C-4802-8C2B-0E2934F3FF96
Doctor, I have very high lp(a). I'm taking Rosuvastatin, and my ApoB is great, but lp(a) can also cause blood to clot, which might explain my family's history of stroke. What can be done about this dangerous effect of lp(a)?
Check our brief view on why apoB conformation matters: journals.lww.com/co-lipidolog... #apoB #atherosclerosis #LDL #lipoproteins #biochemistry #medsky
Quick blog by @BioLayneabout re the scary, and certainly unethical Keto Study - Sponsored Study Showed High LDL-C and apoB Causes RAPID Plaque Progression! | In other words -APOB DOES BEGET PLAQUE www.youtube.com/watch?v=A2hv... @nationallipid.bsky.social @aspcardio.bsky.social
#DrStephenLKopecky preventative cardiologist & director #MayoClinic’s #StatinIntoleranceClinic while ApoA1-a-4, ApoB-100 may B useful, HoFH pts find info useless. Drs say #PCSK9Inhibitors can give U 10Y+ or it may kill U in 24H Dr say statins help but it doesn’t stop disease. Injections killed ppl
ApoB. Also visit familyheart.org/high-lipopro...
Track for longevity
Congrats on the Nat Geo first. But the statin critique precedes influencers by decades, (ApoB is derived from the 1950s discovery of blood lipids and the heterogeneity of LDL) and is hardly a desire to eat whatever you want. People on keto have to forego the tastiest products in the food supply.
I'm a complete stan for retatrutide as a drug and here's another reason. Not only does it lower LDL and triglycerides at statin and fibrate levels...but it lowers all these other remnant cholesterols. It lowers ApoCIII, ApoB, & ANGPTL3/8, it changes FGF21. It does the work of multiple drugs alone!
For those inquisitive about obicetrapib, Archna Bajaj report a kinetic lipoprotein study which provides insight on how the med significantly reduces apoB. x.com/nationallipi... @aspcardio.bsky.social @escardio.bsky.social @familyheartfdn.bsky.social
'we used short AIM assays to characterize APOB-reactive CD4+ T cells in patients with angiographically verified CAD. APOB-reactive CD4+ T cells expressing CD25 & 4-1BB markers were the most abundant. (...) With increasing disease severity, the Treg signature was progressively and significantly lost'
Mild coronary artery disease is associated with a regulatory program in APOB-reactive CD4+ T cells that is replaced by a pro-inflammatory program in patients with severe disease @natcardiovascres.nature.com www.nature.com/articles/s44...
So what did the authors report instead? A post hoc analyses showing that ApoB did not correlate with plaque growth. This is misuse of the data—and it's not acceptable in scientific publishing. 7/14
3️⃣ Traditional lipids don’t predict Lp(a). LDL-C, non–HDL-C, and ApoB did not correlate with Lp(a) across most of its range. ✅ Bottom line: Measure Lp(a) directly—don’t rely on traditional lipids.
Children with COVID or MIS-C show major metabolic changes, like high triglycerides and inflammation, that mirror severe adult COVID infection. These shifts could raise long-term heart risks, especially after MIS-C. More follow-up is urgently needed. buff.ly/f4nIdfO #medsky #pedsky
ApoB, LDL-C and non-HDL-C as Markers of Cardiovascular Risk - Journal of Clinical Lipidology www.lipidjournal.com/article/S193...
Systemic review of discordance studies by Daniel Sehayek, et al. finds apoB generally outperforms LDL-C and non-HDL-C. (prior post of recent study adds to this evidence) #cardiosky www.lipidjournal.com/article/S193...
Converting mean apoB and LDL-C values to population percentiles (using NHANES) shows risk tracks with apoB. (ASCVD % from Figure 1) Results similar for non-HDL-C. /2-fin
Mid-sized
Enlicitide decanoato, péptido macrocíclico que actúa sobre PCSK9 reduce las LDL y mejora el colesterol no HDL, apoB y lipoprotein(a) en pacientes con hipercolesterolemia familiar heterocigota con historia o en riesgo de enfermedad CV aterosclerótica firstwordpharma.com/story/5970389
Association between lower levels of small dense LDL cholesterol and higher ApoB levels were associated with a lower Alzheimer's Disease risk www.neurology.org/doi/full/10....
ApoB and prognosis of patients with chronic coronary syndrome #REC www.revespcardiol.org/en-apob-and...
Tactics will be interesting in today’s Oaks. APOB runners will surely want to ensure a real test given Desert Flower’s stamina doubts but all three have decent chances so hard to envisage any of them being sacrificed as simple pacemakers. Whirl’s Musidora run suggests she might be asked to lead.
Using proviral load as phenotype, small molecule/lipid metabolism and oxidation-reduction GO terms were enriched for AFR, AMR, ASN, EUR datasets. So we performed 1H-NMR #metabolomics: lower major lipid metabolites in HAM patients, including ApoA1, ApoB, total and HDL-cholesterol!
Wagle to cholesterol nie taki ważny, apob trzeba paczeć
En personas delgadas metabólicamente sanas con dieta keto, ni la exposición total ni los cambios en los niveles iniciales de las apoB y LDL se asocian con cambios en la placa coronaria #ASCVD #ketodiet www.jacc.org/doi/10.1016/...
1. Meet Apob AI This is unbelievable! I discovered an AI influencer making more than $500 monthly on Instagram! Build your own AI model in just a minute and start cashing in: mega.apob.ai/SMind
Graphic of the pathways in cholesterol homeostasis - CETP plays a major role transferring CE from HDLs to apoB-particles. Time for all to comprehend that LDLs as well as the small intestine play major roles in RCT. Expert comments on the disproven notion that HDL-C tells you anything about RCT!
(BioRxiv All) Robust Serum Proteomic Signatures of APOE2: We previously identified a signature of 16 serum proteins that highlighted a role of the e2 allele of APOE in lipid regulation via apolipoprotein B (APOB) and apolipoprotein E (APOE), and in inflammation. The serum… #BioRxiv #MassSpecRSS
CONCLUSIONS: Among older SCH patients, levothyroxine treatment may reduce TC, TG, LDL-C, and ApoB. 2/2
Changed my mind on ApoB after hearing Dr Peter Attia talk on ApoB and LDL-C. #ApoB #LDL #Cholesterol
1. Meet Apob AI This is unbelievable! I discovered an AI influencer making more than $500 monthly on Instagram! Build your own AI model in just a minute and start cashing in: mega.apob.ai/SMind
One good thing in the 'One Big Beautiful Bill' is that drugs with more than 1 #orphan indications will be excluded from IRA negotiations. This is relevant for #RNAi #RNAediting and #CRISPR targeting things like TTR, LDL-R, ApoB.
June issue now live, with Reviews on: - ApoB-containing lipoproteins in atherogenesis - Haematometabolism in atherosclerosis - Diversity of cardiac macrophages in health and disease - Phenotyping atherosclerotic plaque and perivascular adipose tissue www.nature.com/nrcardio/vol...
【ビートルズ】 呼んでるのに（I Call Your Name）
1. Meet Apob AI This is unbelievable! I discovered an AI influencer making more than $500 monthly on Instagram! Build your own AI model in just a minute and start cashing in: mega.apob.ai/SMind
LDL-C is only one piece of the lipid puzzle. In this HCPLive video, a panel of experts breaks down why VLDL, HDL, triglycerides, non-HDL, and ApoB matter, and how they can change the way we approach the prevention and treatment of cardiovascular disease. www.hcplive.com/view/other-l...
Related editorial by Sniderman et al. #apoB #Lp(a) #cardiosky academic.oup.com/eurheartj/ad... bsky.app/profile/eric...
LDL-c (now we use non-HDL-c & apoB), hsCRP, and Lp(a) among initially healthy European men and women was predictive of incident major adverse cardiovascular events (heart attacks, strokes, death from heart disease) during a 20-year period. academic.oup.com/eurheartj/ad...
4️⃣ Lp(a) adds independent risk prediction beyond ApoB. 5️⃣ Measuring both ApoB and Lp(a) gives a more accurate assessment of heart disease risk, and including them in routine testing can greatly improve prevention and treatment strategies.
3️⃣ ApoB reflects the total number of atherogenic lipoprotein particles and is a better marker of cardiovascular risk than LDL-C or non-HDL-C.
2️⃣ VLDL particles are more harmful per particle, but since LDL apoB (IDL + LDL) makes up 91% of total apoB particles compared to VLDL's 9%, LDL contributes more to overall cardiovascular risk.
@ThelastStyleb16 @DoctorTro @Drlipid @PeterAttiaMD @ThelastStyleb16 OK Mr. expert here is something to read so you don’t look like an idiot the next time this topic comes up: https://t.co/a9wRIHyXsq
https://t.co/FRmQMMAJ3a.
RT @drpablocorral: @DrLuizSilva1 @pabeda1 @Lpa_Doc Luiz, I really enjoyed the match! I support Boca! Regarding your question, find this ver…
@DrLuizSilva1 @pabeda1 @Lpa_Doc Luiz, I really enjoyed the match! I support Boca! Regarding your question, find this very nice article from Sniderman https://t.co/BmUt0k8Xpr
RT @mak_sysepi: @erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
RT @mak_sysepi: @subC0smos @iTomRichardson @mvholmes @mendel_random @ECSanderson @skathire A very nice take on the apoB issue too https://t…
RT @mak_sysepi: @subC0smos @iTomRichardson @mvholmes @mendel_random @ECSanderson @skathire A very nice take on the apoB issue too https://t…
RT @mak_sysepi: @erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
@Drlipid The May 2019 article pretty much sums the apo B issue up for me & supports your suggestion of going with apo B levels if one has to choose between only accessing apo B level & TG or a lipid panel.Again thanks for directing me to Dr. Sniderman. https://t.co/orYqyy3lmt
RT @mak_sysepi: @subC0smos @iTomRichardson @mvholmes @mendel_random @ECSanderson @skathire A very nice take on the apoB issue too https://t…
RT @mak_sysepi: @subC0smos @iTomRichardson @mvholmes @mendel_random @ECSanderson @skathire A very nice take on the apoB issue too https://t…
@subC0smos @iTomRichardson @mvholmes @mendel_random @ECSanderson @skathire A very nice take on the apoB issue too https://t.co/lfV3zmetro by Allan D. Sniderman, Michael Pencina and @ThanassoulisMD
"Of note, the TC/HDL ratio is mathematically equivalent to the ratio of non-HDL/HDL." Soo, in other words, the *possibly* atherogenic/non-atherogenic. What is one thing that is making non-HDL risky/atherogenic? ApoB. For way more details, see here: https://t.co/rRjnnOItT2 15/n
RT @mak_sysepi: @erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
RT @mak_sysepi: @erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
RT @mak_sysepi: @erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
@erik_arnesen dear all of us lipid people - let's not forget the main culprit, apoB
RT @CliffDominy: Nice apoB review by Sniderman @ThanassoulisMD et al. https://t.co/ZeORmLUBeE
Nice apoB review by Sniderman @ThanassoulisMD et al. https://t.co/ZeORmLUBeE
RT @CircRes: VIEWPOINT: #ApoB - The Power of Physiology to Transform the Prevention of #CardiovascularDisease https://t.co/Ct28tMLugB https…
VIEWPOINT: #ApoB - The Power of Physiology to Transform the Prevention of #CardiovascularDisease https://t.co/Ct28tMLugB https://t.co/oRdVIQp5qe
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