Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes.

Shayan Shamipour, Roland Kardos, Shi-Lei Xue, Björn Hof, Edouard Hannezo, Carl-Philipp Heisenberg

May 2019 Cell

Synopsis of Social media discussions

The discussions demonstrate high interest through phrases like 'wonder no more' and references to the paper as a 'game changer,' which convey excitement and curiosity. Several messages support the research's significance, such as noting the inclusion of RRIDs to improve reproducibility, reflecting appreciation for the scientific rigor. The tone varies from supportive to inquisitive, contributing to a moderate level of engagement and an acknowledgment of the study's relevance.

A
Agreement
 Moderate agreement

Most discussions acknowledge the importance of the research, especially highlighting how biological mechanisms like actin dynamics influence cell behavior, showing general support.

I
Interest
 High level of interest

Participants show high curiosity and enthusiasm, with repeated questions and calls to explore the topic further, indicating strong interest.

E
Engagement
 Moderate level of engagement

Some posts actively promote the paper, sharing summaries and encouraging others to read it, suggesting moderate but meaningful engagement.

I
Impact
 Moderate level of impact

While the discussions recognize the article's significance in understanding cell polarization, there isn't explicit evidence of wide-scale impact beyond the scientific community.

Social Mentions

YouTube

2 Videos

Facebook

3 Posts

Twitter

45 Posts

Blogs

3 Articles

News

8 Articles

Metrics

Video Views

4,181

Total Likes

126

Extended Reach

110,917

Social Features

61

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Actin Dynamics and Cytoplasm Segregation in Zebrafish Oocytes

Actin Dynamics and Cytoplasm Segregation in Zebrafish Oocytes

This timelapse video showcases the movement of fluorescently tagged actin in zebrafish oocytes during the first hour post-fertilization. The actin flows towards the animal pole, causing the cytoplasm to separate from the yolk granules, as documented by IST Austria.

ISTAustria

May 9, 2019

2,171 views

Cytoplasmic and Yolk Segregation in Zebrafish Oocytes

Cytoplasmic and Yolk Segregation in Zebrafish Oocytes

This video features a timelapse of a zebrafish oocyte, showcasing the segregation of cytoplasm from yolk granules during the first four cleavage cycles, captured using confocal microscopy. Observations stem from research led by the IST Austria group, highlighting the dynamics of phase segregation.

ISTAustria

May 9, 2019

2,010 views

  • RRID Robot
    @RobotRrid (Twitter)

    The authors of "Bulk Actin Dynamics Drive Phase Segregation in Zeb…" (https://t.co/CnUosfh8oc) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #OpenScience #STMpublishing
    view full post

    August 9, 2021

  • the paper link
    @the_paper_link (Twitter)

    [trend] up+1: *Shamipour S* et al (Cell) **Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes.** https://t.co/Mv3QM8Elyh
    view full post

    May 16, 2019

  • the paper link
    @the_paper_link (Twitter)

    [trend] new: *Shamipour S* et al (Cell) **Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes.** https://t.co/Mv3QM8Elyh
    view full post

    May 15, 2019

  • Kursad Turksen
    @kursadturksen (Twitter)

    Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes https://t.co/lOlcKItFEj
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    May 12, 2019

  • T⁷ MD,PhD
    @tokitky (Twitter)

    Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes https://t.co/wuBjmqk4IM
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    May 11, 2019

  • Palsamy Kanagaraj
    @kanagooo (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38


  • @AnonRere (Twitter)

    Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes https://t.co/UScQ7z3uQ1
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    May 10, 2019

  • Marie Breau
    @MarieBreau1 (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Jamie B.
    @b_juice20 (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Jasmine Mah @jmah@ecoevo.social
    @jasminelmah (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Ulrich Schwarz (also @ulrichschwarz.bsky.social)
    @SchwarzUlrich (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • * Checks Notes, Shakes Head *
    @balicea1 (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Nathalie Le Bot
    @nat_lebot (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Anusha
    @Anusha_Sathyas (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Ste Tavano
    @SteTavano (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Pavel Tomancak
    @PavelTomancak (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • ISTAustria
    @ISTAustria (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • FranzeLab
    @Franze_Lab (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Ozren Bogdanovic
    @bogdanoviclab (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 10, 2019

    38

  • Nicoletta I Petridou
    @petridou_ni (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 10, 2019

    38

  • Yusuke Toyama
    @Yusuke_Toyama (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • Theory of Living Matter Group
    @TLM_Cambridge (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Héctor Sánchez-Iranzo
    @hsancheziranzo (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Etidio González
    @Don_Etidio (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Tathagata Biswas
    @tathabiswas (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • Peter Lenart
    @LenartLab (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • Wolfgang Keil
    @wolfgang_keil (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • Carlos Pérez-González
    @PerezGonzalezCa (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Philipp Radler
    @radler_philipp (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • stefa/str'oh.hut
    @craspedacuste (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • M.Safa Karagoez
    @mskaragoez (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
    view full post

    May 9, 2019

    38

  • Marina García Macia
    @Juanaloca2002 (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Picard Marion
    @MarionALPicard (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Renno Justine
    @JustineRenno (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
    @Alexis_Lomakin (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Genikhovich Group
    @genikhovich (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

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  • Drosophilosopher
    @HammedBadmos (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • THERY Manuel
    @ManuelTHERY (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Jean-Léon Maître
    @maitrejl (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Kenji Sugioka ~
    @sugi05 (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • Cell Biology J-Club
    @cell_club (Twitter)

    Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes https://t.co/UopgMoKLHf
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    May 9, 2019

    1

  • Clyde Pinto
    @ClydePinto (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

    38

  • the Node
    @the_Node (Twitter)

    RT @HeisenbergCPLab: Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out…
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    May 9, 2019

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  • Heisenberg Lab
    @HeisenbergCPLab (Twitter)

    Have you ever wondered how bulk actin dynamics drive phase segregation in zebrafish oocytes? Wonder no more! Check out our latest paper on @CellCellPress by first author @ShamipourShayan https://t.co/dycDCbrWTY
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    May 9, 2019

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  • Min Dai
    @artofbiology (Twitter)

    Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes https://t.co/ECKIcd5OLV
    view full post

    May 9, 2019

Abstract Synopsis

  • The study reveals that in zebrafish oocytes, ooplasm segregation is driven by a cell cycle-dependent wave of bulk actin polymerization traveling from the animal to the vegetal pole, rather than cortical actin reorganization.
  • This actin wave pulls the ooplasm animally by creating network flows and pushes yolk granules vegetally through a mechanism similar to actin comet formation, facilitating the initial steps of embryo patterning.
  • Researchers used biophysical experiments and theoretical modeling to demonstrate how these actin dynamics contribute to oocyte polarization and the segregation of maternal determinants.]