July 2019 PMID 31099038

Kratom Use and Toxicities in the United States.

William Eggleston, Robert Stoppacher, Kyle Suen, Jeanna M Marraffa, Lewis S Nelson

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Mentions

125
Peak: 43 in Jul 2019
across 7 sources since May 2019

Extended reach

332,031
potential audience

Total likes

2,329

Video views

163,718

Mentions per month

May 2019 – Apr 2025

Where it's discussed

  • X / Twitter64 posts
  • News44 articles
  • Blogs5 articles
  • Facebook4 posts
  • Reddit4 posts
  • YouTube3 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a consensus that kratom has notable toxicities, with posts citing specific data on adverse effects and poison center reports, demonstrating strong engagement. References to expert reviews, such as Dr. Jack Henningfield's critique, and endorsements from organizations like the American Kratom Association highlight the discussion's depth and impact on public perception and policy debates.

AgreementStrong agreement

Most posts support the findings that kratom poses health risks and highlight its toxicities, showing strong agreement with the publication.

InterestHigh interest

Numerous posts discuss the article in detail, referencing toxic effects, critiques, and endorsements, indicating high interest.

EngagementHigh engagement

Many comments analyze research critiques, cite experts like Dr. Jack Henningfield, and discuss regulatory issues, reflecting deep engagement.

ImpactHigh impact

The widespread sharing, expert endorsements, and calls for more research emphasize the publication's significant influence on public health discussions.

Top posts

Most liked on X and Bluesky
Pharmacotherapy
@PharmacoJournal · X

New Podcast: Learn about KRATOM, its use and toxicities in the US from this fascinating discussion with @williedoestox. https://t.co/zm58sZzCHD @UpstateNews @BingPharmacy Full manuscript available at: https://t.co/lsre2kcmoL https://t.co/4KOUrC6lIG

Jul 10, 2019 · 13 likes · 4 shares · 11,866 followers View post →
Pharmacotherapy
@PharmacoJournal · X

A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing alkaloids with opioid properties. https://t.co/gW1qK8brfx @williedoestox @Wiley_Health https://t.co/15zVguTbpL

May 21, 2019 · 13 likes · 6 shares · 11,866 followers View post →
Mac Haddow
@MacHaddow1 · X

https://t.co/Q7Ft3zokod

Jul 16, 2019 · 7 likes · 4 shares · 222 followers View post →
Pharmacotherapy
@PharmacoJournal · X

A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing alkaloids with opioid properties. https://t.co/lB6rpR09mB @williedoestox https://t.co/VhHUpBb1hM

Jun 6, 2019 · 4 likes · 1 share · 11,866 followers View post →
Lucas Hill, PharmD, FCCP
@HillPharmD · X

Kratom appears to agonize mu & delta opioid receptors. Chronic use is associated with opioid-like adverse effects, tolerance, & withdrawal. A retrospective review of poison center data by @WillieDoesTox found a range of potential toxicities. https://t.co/1YlVrcyHiY

May 24, 2021 · 4 likes · 3,971 followers View post →
Thom “NAC” Mack
@ThommyTox · X

@jmugele @NaturesPoisons “Methy” seems to fall in line with data from the U.S.’s National Poison Data. https://t.co/HHhnzDuG2F

May 18, 2021 · 4 likes · 1,062 followers View post →

All mentions

Atkina Starling
@atkinastarling · X

RT @Kimberl79809348: @RealJamesWoods Kratom Use and Toxicities in the United States https://t.co/5uqYmWyzND

Apr 17, 2025 · 1 share · 7,261 followers View post →
KimberlyA
@Kimberl79809348 · X

@RealJamesWoods Kratom Use and Toxicities in the United States https://t.co/5uqYmWyzND

Apr 17, 2025 · 3 likes · 1 share · 432 followers View post →
KimberlyA
@Kimberl79809348 · X

@p8stie #kratom "Kratom use is increasing and is associated with significant toxicities.Our findings suggest kratom is not reasonably expected to be safe and poses a public health threat due to its availability as an herbal supplement." https://t.co/5uqYmWyzND

Apr 17, 2025 · 2 likes · 432 followers View post →
Floyd Maxwell
@justthinkit · X

Today's dog walk was the "pick up the re-sealed 'Green Borneo' pouch with 17 Kratom pills still in it & flush them down the drain" one: https://t.co/bRoAQahAeE "Kratom is associated with significant toxicities, not reasonably expected to be safe and poses a public health threat"

Oct 28, 2023 · 3,169 followers View post →
Willie Eggleston
@WillieDoesTox · X

RT @PharmacoJournal: This Editor's Choice manuscript emphasizes the need for thorough & accurate medication histories from all patients and…

Sep 20, 2021 · 1 share · 684 followers View post →
Pharmacotherapy
@PharmacoJournal · X

This Editor's Choice manuscript emphasizes the need for thorough & accurate medication histories from all patients and an awareness of the potential toxicity of supplements. https://t.co/lsre2kcmoL @WillieDoesTox @binghamtonu @UpstateNews https://t.co/pobWhaW6Xg

Sep 20, 2021 · 3 likes · 1 share · 11,866 followers View post →
Lucas Hill, PharmD, FCCP
@HillPharmD · X

Kratom appears to agonize mu & delta opioid receptors. Chronic use is associated with opioid-like adverse effects, tolerance, & withdrawal. A retrospective review of poison center data by @WillieDoesTox found a range of potential toxicities. https://t.co/1YlVrcyHiY

May 24, 2021 · 4 likes · 3,971 followers View post →
Thom “NAC” Mack
@ThommyTox · X

@jmugele @NaturesPoisons “Methy” seems to fall in line with data from the U.S.’s National Poison Data. https://t.co/HHhnzDuG2F

May 18, 2021 · 4 likes · 1,062 followers View post →
Natural Medicine Man
@KratomCannabis · X

RT @MacHaddow1: https://t.co/Q7Ft3zokod

Oct 23, 2020 · 4 shares · 1,440 followers View post →
SUDs PharmD Trainees
@SUDsPharmD_APPE · X

by: @tessa_brighton https://t.co/b5EZPtsMmm

Sep 6, 2020 · 188 followers View post →
kratom
@kratom05292239 · X

American Kratom Association has endorsed the latest review and critique of Eggleston et al.'s report "Kratom Use and Toxicities in the United States" by Dr. Jack Henningfield, a renowned kratom expert. https://t.co/Bt5t5X53ng

Feb 12, 2020 · 581 followers View post →
kratom
@kratom05292239 · X

Dr. Eggleston's latest report on kratom "Kratom Use And Toxicities In The United States" has unfortunately failed to garner positive reviews. One of the reasons cited for this is data limitations. https://t.co/g2CnRgIFjg

Feb 12, 2020 · 2 likes · 581 followers View post →
kratom
@kratom05292239 · X

Kratom expert Dr. Jack Henningfield has questioned the Eggleston et al. brief report on "Kratom Use And Toxicities In The United States." He believes few, if any, conclusions can be drawn from the report. https://t.co/VZDZCYvmZY

Feb 11, 2020 · 2 likes · 581 followers View post →
MWU_Pharmacology_IL
@MWUPharmacology · X

Mwu Pharmacology IL faculty Walter Prozialeck coauthored an article titled, "Critique of 'Kratom Use and Toxicities in... https://t.co/pTX5x9UTfJ

Nov 20, 2019 · 2 likes · 136 followers View post →
JoeTurner4k
@Williamjturner7 · X

@MariSchaefer @PhillyInquirer This is Dr Jack Henningfield contradicting Eggleston's findings regarding the calls to poison control center. https://t.co/xlTpS5xwPX

Aug 28, 2019 · 1 like · 578 followers View post →
Emtiro Health
@EmtiroHealth · X

Kratom is an herbal supplement containing alkaloids with opioid properties. Kratom use is increasing and is associated with significant toxicities. Read more: https://t.co/KuJoLsEO1y

Aug 22, 2019 · 108 followers View post →
JoeTurner4k
@Williamjturner7 · X

@dailyherald @NapervilleIL Dr Jack Henningfield's contradiction to Eggleston's recent findings regarding call's to the Poison Control Center. https://t.co/xlTpS5xwPX

Aug 17, 2019 · 2 likes · 578 followers View post →
Pharmacotherapy
@PharmacoJournal · X

Learn about KRATOM, its use and toxicities in the US from this fascinating discussion with @williedoestox. https://t.co/zm58sZzCHD @UpstateNews @BingPharmacy Full manuscript available at: https://t.co/y0is3BoFYe https://t.co/MIUt5EBFc9

Jul 31, 2019 · 2 likes · 11,866 followers View post →
Bethany Cook
@sweetiekins22 · X

RT @MacHaddow1: https://t.co/Q7Ft3zokod

Jul 25, 2019 · 4 shares · 597 followers View post →
CESAR Research
@CESAResearch · X

US #kratom exposure (2011-2018): A total of 2,312 kratom exposures were reported, and the drug was listed as a cause or contributing factor of 4 deaths. Some of the serious effects observed were seizures, withdrawal, and hallucinations. https://t.co/FTbqxM5gjm https://t.co/JY7SyaRwtT

Jul 22, 2019 · 1 like · 1,018 followers View post →
Speciosa Guide
@SpeciosaGuide · X

Dr. Jack Henningfield's review on the recently published report "Kratom Use And Toxicities In The United States" is worth reading. #Kratom #KeepKratomLegal https://t.co/OlGDuTLd8S https://t.co/dJijvAGxt5

Jul 22, 2019 · 527 followers View post →
Melody
@MelodyHope5 · X

@WebMD Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@mybetterbrain Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@GeneticLiteracy @EdCara4 @Gizmodo Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@RebeccaDean1972 @UPI Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@matelife_health Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@Carehealthpharm Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@PaPaShArMFbI @UPI Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@man4luve @circleboom Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@Healthnewsguy Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@ForHealthNews Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@Yo_Buzz1 Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@bestnewsicu Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@PaperOpen Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@easybodyfit Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@DurrWattersrxt Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@MetroZoneIndia Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@SMIBarry Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@greeenorg Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@MedkitInfo Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@wbtrade1 Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@velobiotics Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@Drugscom Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 18, 2019 · 1,385 followers View post →
Vashti Fox-Lewis
@VashtiFoxLewis2 · X

The American Kratom Association Strongly Endorses Dr. Jack Henningfield's Review That Questions The Conclusions Related To Kratom Safety In The Eggleston Et Al. Brief Report On "Kratom Use And Toxicities In The United States" https://t.co/sk3yFLHWx9

Jul 17, 2019 · 1,097 followers View post →
Robin Graham
@AKARobinG · X

RT @MacHaddow1: https://t.co/Q7Ft3zokod

Jul 17, 2019 · 4 shares · 906 followers View post →
Melody
@MelodyHope5 · X

@WholeFoodsMag Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 16, 2019 · 1 share · 1,385 followers View post →
Melody
@MelodyHope5 · X

@HavenHouse_ Addiction Specialist Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking kratom“lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 16, 2019 · 1,385 followers View post →
Melody
@MelodyHope5 · X

@SSA_Addiction Addiction Specialist Jack Henningfield, Ph.D., Johns Hopkins University School of Medicine, says new report attacking kratom lacks the scientific rigor to support its conclusions about kratom use and safety”. https://t.co/VrDTpLcbXb

Jul 16, 2019 · 1,385 followers View post →
Mac Haddow
@MacHaddow1 · X

https://t.co/Q7Ft3zokod

Jul 16, 2019 · 7 likes · 4 shares · 222 followers View post →
Melody
@MelodyHope5 · X

@SSA_Addiction Jack Henningfield, Ph.D., of The Johns Hopkins University School of Medicine, says new report attacking #kratom “lacks the scientific rigor to support its conclusions about kratom use and safety”. More research is needed to show benefits of kratom! https://t.co/VrDTpLcbXb

Jul 16, 2019 · 1 like · 1 share · 1,385 followers View post →
Stocks News Feed
@feed_stocks · X

The American Kratom Association Strongly Endorses Dr. Jack Henningfield’s Review That Questions The Conclusions Related To Kratom Safety In The Eggleston Et Al. Brief Report On “Kratom Use And Toxicities In The United States” https://t.co/2FohGxUi7i

Jul 16, 2019 · 4,212 followers View post →
A&D History
@drughistory · X

RT @SSA_Addiction: #Kratom Use and Toxicities in the United States - Eggleston - 2019 - Pharmacotherapy: The Journal of Human Pharmacology…

Jul 11, 2019 · 1 share · 1,809 followers View post →
Society for the Study of Addiction
@addiction-ssa.org · Bluesky

#Kratom Use and Toxicities in the United States - Eggleston - 2019 - Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Wiley Online Library https://buff.ly/2YPNOFu

Jul 11, 2019 · 1 like View post →
Society for the Study of Addiction
@SSA_Addiction · X

#Kratom Use and Toxicities in the United States - Eggleston - 2019 - Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Wiley Online Library https://t.co/tULttbkfzq https://t.co/UVXHdqDPBF

Jul 11, 2019 · 1 like · 1 share · 8,757 followers View post →
W. Clay Jackson
@mydocjackson · X

Kratom Use and Toxicities in the United States - Eggleston - 2019 - Pharmacotherapy // Buyer beware: seizures, agitation, & withdrawal associated with kratom. Just because it’s “natural” doesn’t make it good. Ebola is all-natural. https://t.co/iWL1yWaMKe

Jul 10, 2019 · 1 like · 2,811 followers View post →
EM/CCC
@EMCCC2 · X

RT @PharmacoJournal: New Podcast: Learn about KRATOM, its use and toxicities in the US from this fascinating discussion with @williedoestox…

Jul 10, 2019 · 4 shares · 885 followers View post →
Willie Eggleston
@WillieDoesTox · X

RT @PharmacoJournal: New Podcast: Learn about KRATOM, its use and toxicities in the US from this fascinating discussion with @williedoestox…

Jul 10, 2019 · 4 shares · 684 followers View post →
Pharmacotherapy
@PharmacoJournal · X

New Podcast: Learn about KRATOM, its use and toxicities in the US from this fascinating discussion with @williedoestox. https://t.co/zm58sZzCHD @UpstateNews @BingPharmacy Full manuscript available at: https://t.co/lsre2kcmoL https://t.co/4KOUrC6lIG

Jul 10, 2019 · 13 likes · 4 shares · 11,866 followers View post →
Robert West, PhD ✝️
@westr · X

Herbal supplement #kratom used to treat #addiction and #pain found unsafe by researchers https://t.co/INl2Hj1GfJ via @binghamtonu @EurekAlert @UpstateNews The paper, "Kratom Use and Toxicities in the United States," was published in Pharmacotherapy.

Jul 9, 2019 · 1 like · 19,297 followers View post →
Andrew McKusick
@ndmcq6 · X

Kratom Use and Toxicities in the United States - Eggleston - 2019 - Journal “Pharmacotherapy” https://t.co/KkjaQ5p2bi

Jul 9, 2019 · 1,374 followers View post →
Pharmacotherapy
@PharmacoJournal · X

A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing alkaloids with opioid properties. https://t.co/lB6rpR09mB @williedoestox https://t.co/VhHUpBb1hM

Jun 6, 2019 · 4 likes · 1 share · 11,866 followers View post →
Willie Eggleston
@WillieDoesTox · X

RT @PharmacoJournal: A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing a…

May 21, 2019 · 6 shares · 684 followers View post →
EM/CCC
@EMCCC2 · X

RT @PharmacoJournal: A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing a…

May 21, 2019 · 6 shares · 885 followers View post →
JACCP
@JACCPJournal · X

RT @PharmacoJournal: A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing a…

May 21, 2019 · 6 shares · 5,305 followers View post →
Pharmacotherapy
@PharmacoJournal · X

A review to determine the toxicities associated with kratom use in the US. Kratom is an herbal supplement containing alkaloids with opioid properties. https://t.co/gW1qK8brfx @williedoestox @Wiley_Health https://t.co/15zVguTbpL

May 21, 2019 · 13 likes · 6 shares · 11,866 followers View post →