Overall, the discussions reflect strong support and curiosity about the scientific insights, as seen in remarks like 'corroborates the importance of E protein' and questions about its role in pathogenesis, showing a thoughtful examination of the article’s content and its implications for vaccine development and understanding virus behavior.
AgreementModerate agreement
Most discussions acknowledge and validate the current understanding presented in the publication, with many emphasizing the importance of ongoing research.
InterestHigh interest
The majority of social discussions show high curiosity about the E protein’s role and its implications for vaccine development, keeping the topic engaging.
EngagementModerate engagement
Participants often reference scientific details, mention related studies, and express opinions, indicating a moderate to deep level of engagement.
ImpactModerate impact
These discussions highlight the significance of understanding the E protein for controlling current and future coronavirus outbreaks, suggesting a moderate impact.
Abstract in brief
Coronaviruses primarily infect birds and mammals, but can jump to humans, as seen in outbreaks like SARS and MERS, which can be deadly, prompting increased research into their biology.
The coronavirus envelope (E) protein is a small but essential part of the virus involved in processes like virus assembly, envelope formation, and causing disease, and recent studies have explored its structure, functions, and interactions with other viral and host proteins.
While significant progress has been made—especially in understanding the E protein's role in SARS-CoV—there are still many unknowns, and ongoing research is crucial for developing vaccines and antiviral treatments for human and animal coronaviruses.]
Aug 25, 2020 · 23 likes · 1 share · 71,688 followersView post →
J
JChoe
@JoohnChoe · X
Coronaviruses are already ferociously complex, highly evolved entities we're still understanding.
As of late '19, Schoeman & Fielding's literature review noted major gaps in the basic state of knowledge of critical envelope proteins, for instance.
https://t.co/Yrxxxa0nPM https://t.co/XMs33BWFIF
Aug 21, 2023 · 22 likes · 3 shares · 18,648 followersView post →
DB
D. Janković (aka Dog's Breakfast)
@breakfast_dogs · X
@KeithEv84928885 @CharlesRixey @quay_dr @DrLiMengYAN1 @pathogenetics @Mona Just gonna leave this here - current knowledge (as at May 2019) about SARS 1 E Protein. I've looked at a couple of papers (e.g. Malik Peiris et al) but might be some more clues in the references as to who had an interest in E protein and why?
https://t.co/3Cr7b43w8c
4/21
The science does seem to check out, at least to my layman eyes, although I'd defer further examination to an expert (@Neurophysik?). Here's a paper by two molecular biologists from the University of Western Cape, Cape Town, that seems to corroborate.
https://t.co/t4lmxjyukG
Aug 10, 2020 · 12 likes · 1 share · 64,496 followersView post →
AS
Andrew J. Steinmetz
@ajsteinmetz.com · Bluesky
(5/6) Above quotes from: Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). doi.org/10.1186/s129...
COVID19 httpsvirologyjbiomedcentralcomarticles101186s1298501911820. The coronavirus envelope protein is essential for virus assembly, envelope formation, and disease causation. Ongoing research aims to develop vaccines…
You might have heard that vaccine trials are currently underway in Seattle. What exactly is being tested, how long will it take, and when can we expect a COVID-19 vaccine? Experts discuss the process, structure of the…
Coronavirus envelope (E) protein is crucial for virus assembly and pathogenicity. This video explores recent findings on its structure, functions, and interactions, highlighting its importance in developing vaccines and…
This video discusses the coronavirus envelope (E) protein, its structure, functions in virus assembly, envelope formation, and its impact on disease progression, highlighting ongoing research necessary for developing…
@Ticklicker56 @gadboit @mbw61567742 @Roper_Lab @3GHtweets @herzogfa @Dissenting2020 @BillyBostickson @Kevin_McKernan @_John_Reed @DonnaGay8989 @ryanbeed @A1responder @DrBMcDH @JohnBeaudoinSr @TammyRenee2567 @chrismartenson @CogburnMrs @shimjelly @TnAlistair @AskDrDrew @drdrew @ECUBrodySOM @ban_epp_gofroc @quay_dr @R_H_Ebright @nizzaneela @MJnanostretch Current Knowledge," Virology Journal 16 no. 1 (2019): 69, doi: 10.1186/s12985-019-1182-0). Curiously, this exact E protein sequence had been seen years before in two previously collected viruses and would have been expected to change in the time since. Yet SARS2 had an identical
RT @JoohnChoe: Coronaviruses are already ferociously complex, highly evolved entities we're still understanding.
As of late '19, Schoeman…
Aug 21, 2023 · 3 shares · 190 followersView post →
FF
fugit cum forfex
@fugitcumforfex · X
RT @JoohnChoe: Coronaviruses are already ferociously complex, highly evolved entities we're still understanding.
As of late '19, Schoeman…
Aug 21, 2023 · 3 shares · 4,462 followersView post →
J
JChoe
@JoohnChoe · X
Coronaviruses are already ferociously complex, highly evolved entities we're still understanding.
As of late '19, Schoeman & Fielding's literature review noted major gaps in the basic state of knowledge of critical envelope proteins, for instance.
https://t.co/Yrxxxa0nPM https://t.co/XMs33BWFIF
Aug 21, 2023 · 22 likes · 3 shares · 18,648 followersView post →
Jun 10, 2023 · 1 share · 1,189 followersView post →
AK
A.Kruschke
@a_kruschke · X
@yozo_oba @Minidgp それよりも少し複雑です、、、。
E-protein SARS-CoV-2
https://t.co/yHjF4TtIFv
E-protein SARS-CoV-1 !!!!!!
(article from year 2019)
https://t.co/Z2JLeEkm7m
... Ideas for medical uses...
https://t.co/O1zDAtbafT
Jun 10, 2023 · 1 like · 1 share · 1,491 followersView post →
TF
temujin Gengis Khan #FREXIT
@gengist17 · X
RT @AnneliseBocquet: @marc_g_wathelet @MartinZ_uncut Schoeman et al. 2019 (https://t.co/QYm3rorlv2 mis en référence), explique en introduct…
@marc_g_wathelet @MartinZ_uncut Schoeman et al. 2019 (https://t.co/QYm3rorlv2 mis en référence), explique en introduction que la S est responsable de la fusion entre le virus et la cellule cible. La protéine E génère bien des canaux transmembranaires mais pour permettre aux nouveaux virions de s'assembler et
Jun 8, 2023 · 2 likes · 3 shares · 30,531 followersView post →
G
GrinerATodd
@supertodd1 · X
RT @janey15408827: Once upon a time not so long ago .....
https://t.co/jGj7ryZN3z
May 28, 2023 · 1 share · 1,570 followersView post →
J
janey
@janey15408827 · X
Once upon a time not so long ago .....
https://t.co/jGj7ryZN3z
May 28, 2023 · 1 like · 1 share · 341 followersView post →
@CathNoakes @PrasadKasibhat1 @linseymarr @jljcolorado This is an interesting review https://t.co/qIouj4e68K palmitoylation could be a mechanism to increase hydrophobic ity of envelope protein. But in main it is hydrophilic except transmembrane domain.
Some coronaviruses kill, while others cause a common cold. We are getting closer to knowing why @ConversationEDU https://t.co/iHIEoa5buv https://t.co/oEvwrcvSql
@KeithEv84928885 @CharlesRixey @quay_dr @DrLiMengYAN1 @pathogenetics @Mona Just gonna leave this here - current knowledge (as at May 2019) about SARS 1 E Protein. I've looked at a couple of papers (e.g. Malik Peiris et al) but might be some more clues in the references as to who had an interest in E protein and why?
https://t.co/3Cr7b43w8c
A paper from 2019 says we don't know much at all about the E protein of SARS-Cov, has that changed wrt/ SARS-Cov-19?
"The E protein is the smallest of the major structural proteins, but also the most enigmatic.
https://t.co/CUnWbWAuEr
@ScottAdamsSays My guess is that high winds would tend to abrade and the membrane.
"The CoV envelope (E) protein is a small, integral membrane protein involved in several aspects of the virus’ life cycle, such as assembly, budding, envelope formation, and pathogenesis."
https://t.co/UeSTm6TDuK
RT @aboutmecfs: @Doctor_IMF @Cov19longtail You may be on to something here.
The "E" protein is predicted to be a viroporin that punches ho…
Oct 20, 2020 · 1 share · 2,945 followersView post →
PR
Phoenix Rising
@aboutmecfs · X
@Doctor_IMF @Cov19longtail You may be on to something here.
The "E" protein is predicted to be a viroporin that punches holes in the endoplasmic reticulum (ER), releasing Ca2+ ions into the cytoplasm.
This dramatically alters the depolarization dynamics of neurons and heart cells.
https://t.co/nNhy6r8wVU
Oct 19, 2020 · 1 like · 1 share · 6,193 followersView post →
D
Dave
@davecoughlan80 · X
@KeithMillsD7 @WHO The reality of SARS-CoV2 like other coronaviruses, is that it's an enveloped virus that spreads easily in cold dry conditions. This has known for a long time. It's a winter virus.
https://t.co/X94WtOWIFW https://t.co/zLLo5NREBf
RT @Schandillia: 4/21
The science does seem to check out, at least to my layman eyes, although I'd defer further examination to an expert (…
Aug 10, 2020 · 1 share · 1,377 followersView post →
AS
Amit Schandillia
@Schandillia · X
4/21
The science does seem to check out, at least to my layman eyes, although I'd defer further examination to an expert (@Neurophysik?). Here's a paper by two molecular biologists from the University of Western Cape, Cape Town, that seems to corroborate.
https://t.co/t4lmxjyukG
Aug 10, 2020 · 12 likes · 1 share · 64,496 followersView post →
GR
Generalissimo Rabbit
@NotGniwerb · X
@possumkratom69 nm I found the links to bofa
https://t.co/7ejWoUQ4sD
Dr Randeep Guleria is thankfully, NOT Bothered abt the Cov2 Mutations. He is focussed on Protein 'S' of the Virus like all Vaccine Gold Rush Prospectors. Hope is as much forgiveable abt the Proteins - E, M & N. https://t.co/OOMnvWzcUg
#irresponsables
Existe registro d 39 especies d coronavirus (International Commite on Taxonomy of Viruses) y la mayoría d las personas se infectan con estos virus en algún momento de su vida (Schoeman, D; Fielding, B (2019). «Coronavirus envelope protein: current knowledge»)
@scottycknight @nee_haynes @Yamiche Doesn't mean it can't spread, just that it's a lot harder in hot and humid places. Florida is typically hot and humid.
https://t.co/yqRkHomeDk
https://t.co/aGSaCsaubc
Jun 10, 2020 · 2 likes · 1,315 followersView post →
SD
Scott ENVIRO Denson
@EnviroSmartGOP · X
RT @EnviroSmartGOP: https://t.co/1ODM4pu4u9 Effect of HGH on Avian and Bat CoronaVirus
Jun 10, 2020 · 2 shares · 3,145 followersView post →
اشعب شخصن كل حاجه
بطلو سطحية وبصو للفائدة ، العلم بقى سهل الوصول إليه من خلال الفيديوهات إلى بتبسط المعلومة وتخليها تفاعليه
دعم هنا
https://t.co/zTfYr30Zwf
شكرا للدحيح
#الدحيح_حرامي
May 11, 2020 · 3 shares · 2,976 followersView post →
MJ
Mikala Jordon
@mikalajsisco · X
Coronavirus envelope protein activity has been recently confirmed to drive VLP production. Without this activity the virion would be unable to mature and propagate, making the envelope protein essential for the viruses pathogenesis. https://t.co/xscU7B2fnW #BMS525
Gracias, Diana. Acceso negado a página q me envías pero https://t.co/zVb0mTn0FX + lo q dice Dra. bióloga molecular J. Mikovitz https://t.co/OEuBZNgiOL Más esta tremenda información: https://t.co/oDdL06VpBr #Infórmate. https://t.co/U4NEMxGz4N
https://t.co/t1xpFZfV3p
despite attempts to inhibit ion channel activity in SARS-CoV E, by mutating N15A and V25F, viruses restored ion channel activity by incorporating additional mutations after several passages. https://t.co/is6PhDn7HM
May 3, 2020 · 2 likes · 3 shares · 11,096 followersView post →
BM
bright maroon
@brightmaroon · X
The primary & secondary structure reveals that E has a short, hydrophilic amino terminus consisting of 7–12 amino acids, followed by a large hydrophobic transmembrane domain (TMD) of 25 amino acids, & ends with a long, hydrophilic carboxyl terminus...boom https://t.co/v8T2IJUEF9
@jamespat1301 @AdoreyouManila @AlfieDeyes " In summary, ethanol (60 to 85%), isopropanol (60 to 80%) and n-propanol (60 to 80%) have very good activity against vegetative bacteria, mycobacteria, yeasts, dermatophytes, and enveloped viruses" - Coronavirus envelope protein: current knowledge
Dewald Schoema
(a)Credibile Stats for The Countries of Djibouti, Iran and Israel as at 09.04.2020
(b)A simple explanation of how the how COVID-19 works
[more detailed:
https://t.co/37HBQpe2wR
https://t.co/VkxLp6cPYH
https://t.co/M2YBbBVf5N
https://t.co/haL0bRLUNe] https://t.co/SHhebPqCwt
@AdamSerwer Look at this. Because they renamed it covid-19 or SARS COV-2 they are trying to lie to us because most people don't pay attention to the science but the science says that this virus that they're looking at in May 2019 mutated on the jump.
https://t.co/gIxZ3esf8L
@ztsamudzi
Comparing the science on the Covid19
They were studying this exact virus and its jump to humans early may 2019
https://t.co/gIxZ3esf8L
So the only thing they did was renamed it because it jumped to us and mutated?
@AndrewYang @jbouie Let's not be foolish year they've known about this virus for a very long time tell me that this is not the same virus.
https://t.co/gIxZ3esf8L
@mitchellvii The false positives and false negatives are probably off the charts random. We will never know, because they never did a proper study. The science is very new.
https://t.co/TfR1f8cIX0
Mar 31, 2020 · 1 like · 1 share · 546 followersView post →
D
dbillyx
@dbillyx · X
RT @sigma1721: Muy interesante artículo: https://t.co/qNWV9GBnGa
Explicaría por qué se usa tanto el alcohol en gel, aunque la capside esté…
@BonbonFork @halvorz I passed the question on to my wife and she suggested the following looked good: "Coronavirus envelope protein: current knowledge Dewald Schoeman and Burtram C. Fielding*"
Mar 23, 2020 · 1 like · 2,673 followersView post →
D
Dreamgbutterfly
@dreamgbutterfly · X
Coronavirus envelope protein: current knowledge
https://t.co/EzMgde9CBu
Coronavirus envelope protein: current knowledge | Virology Journal | Full Text
https://t.co/X0IhrMjOS9
Future perspectives and conclusion
今後の展望と結論 https://t.co/lTAFgfKNVF
Feb 3, 2020 · 1 share · 2,082 followersView post →
PW
Paul Worth
@americadiaspora · X
@DavidBCollum @zerohedge (2019) Coronavirus envelope protein: current knowledge
"The outbreak of (SARS) in 2003 and, more recently, Middle-East respiratory syndrome (MERS) demonstrate lethality of CoVs when they cross the species barrier and infect humans."
https://t.co/Azvz8qTAlr
در یک تحقیق دیگر https://virologyj.biomedcentral. com/articles/10.1186/s12985-019-1182-0/figures/1 با توضیح سادتر پروتیین پوش ویروس کرونا را نشان داده است.
Biology - دنا DNA یک مولکول درشت ارگانیک است و اغلب ویروسها ...
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در یک تحقیق دیگر https://virologyj.biomedcentral. com/articles/10.1186/s12985-019-1182-0/figures/1 با توضیح سادتر پروتیین پوش ویروس کرونا را نشان داده است.