CNS Drugs August 2019 PMID 31144270

Methylene Blue in the Treatment of Neuropsychiatric Disorders.

Martin Alda

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Mentions

67
Peak: 8 in Apr 2023
across 4 sources since Aug 2019

Extended reach

441,749
potential audience

Total likes

6,122

Video views

201,707

Mentions per month

Aug 2019 – Aug 2025

Where it's discussed

  • X / Twitter58 posts
  • YouTube4 videos
  • Blogs3 articles
  • Reddit2 posts

AI synopsis

What people are saying

Participants express strong support and curiosity about methylene blue's therapeutic potential, citing studies and personal anecdotes with words like 'miracle' and 'promising results.' The tone varies from cautious optimism to active engagement, highlighting both scientific interest and personal relevance.

AgreementModerate agreement

Most discussion participants recognize the potential benefits of methylene blue for neuropsychiatric conditions, especially bipolar disorder, showing general support.

InterestHigh interest

Many contributors display high curiosity and mention ongoing research, historical use, and personal experiences, indicating strong interest.

EngagementHigh engagement

Several posts delve into specifics, share sources, or describe personal experiences, reflecting deep involvement and critical engagement.

ImpactModerate impact

While some mention the need for cautious use, the overall tone suggests that this discussion could influence viewpoints or prompt further exploration in treatment considerations.

Abstract in brief

  • Methylene blue is a long-standing drug with various mechanisms that give it multiple clinical effects, including antidepressant, anxiolytic, and neuroprotective properties supported by animal and human studies.
  • It stabilizes mitochondrial function and influences reactive oxygen species, making it promising for treating neurodegenerative disorders and providing neuroprotection.
  • In psychiatry, methylene blue has been used for over a century to treat mood and psychotic disorders, showing particularly promising results in bipolar disorder by improving stability and reducing residual symptoms without causing mania, although caution is advised due to its monoamine oxidase A inhibitory effects.]

Top posts

Most liked on X and Bluesky
Vance
@VanceE · X

Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene blue in bipolar disorder led to a better stabilization and a reduction in residual symptoms of the illness.” https://t.co/mUtN6FyFef

Jun 28, 2024 · 53 likes · 8 shares · 42,905 followers View post →
Alzhacker
@Alzhacker · X

https://t.co/07dNdXjAg3 メチレンブルーには多数の生化学的作用があり、これらのどれかを特定の臨床作用と関連付けることは容易ではない。この点では,単一の生化学的経路に限定されない複雑な薬理作用を有している。しかし、どちらも現在の精神医学において最も効果的な薬の一つである。

Sep 18, 2021 · 30 likes · 3 shares · 32,859 followers View post →
☀️MitoHacker☀️
@mitokondriac · X

@heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as aging, are consequence of the energy loss and its related inflamation. Reminder: Methylene blue helps with "mitochondrial fitness". Good, save and cheap. https://t.co/nD8thAhSw3

Apr 11, 2023 · 22 likes · 6 shares · 22,122 followers View post →
Vitalholis
@vitalholis · X

1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jul 9, 2024 · 12 likes · 5 shares · 19,150 followers View post →
William Halden MD
@WilliamHalden · X

@Fynnderella1 @MdBreathe @RobertKennedyJr antidepressants' efficacy is very questionable—Big Pharma hid some unfavorable data about them: https://t.co/EwSlp3YDDk And there may be better natural or cheaper alternatives that are not patentable by Big Pharma: https://t.co/sImQs40Sl2 https://t.co/9kPKyANb5C

Jun 5, 2023 · 9 likes · 1 share · 762 followers View post →
Vance
@VanceE · X

https://t.co/mUtN6FyFef

Apr 13, 2025 · 8 likes · 1 share · 42,905 followers View post →

All mentions

Bharata Ishaya
@bharataishaya · X

@NiallHarbison Try Methylene Blue: https://t.co/3cXwsreMMy

Aug 5, 2025 · 73 followers View post →
threestans02
@threestans02 · X

@RickU @DrNeilStone MB is not pseudoscience. The vaccine is not pseudoscience either, just BAD science. Do you know what pseudoscience even is? https://t.co/UO0n8izs7W What’s that first line say ?

Jul 9, 2025 · 46 followers View post →
Tony DeMarco
@OakSmith2018 · X

@Homtanks669 @shawnsafk @AmiriKing It actually looks like good shit for anyone. I'll have to try it. It's probably safer than kratom. https://t.co/JG89qiRQnB

Jun 25, 2025 · 1,032 followers View post →
Beyond Skincare
@beyondskincare_ · X

@grok @lamboemre Alzheimer - MB https://t.co/f5YlOXoQtl. Dopamin - Parkinson -MB = ADHD'de dopamin eksikliği yaygındır. https://t.co/09VuyRLfYH Nöropsikiyatrik Bozuklukların Tedavisinde Metilen Mavisi https://t.co/QTR9aMNbUI Evet daha çok çalışmaya ve deneye ihtiyaç var ancak yapılan

Jun 18, 2025 · 5 likes · 3,945 followers View post →
Dr. Michael Moeller, ND
@DoctaMoe · X

If you're going to use MB, use what I trust:

May 21, 2025 · 396 followers View post →
Dr. Michael Moeller, ND
@DoctaMoe · X

Everyone's just now “discovering” methylene blue? Brother... I’ve been using it since 2019.

May 21, 2025 · 396 followers View post →
Ned17Flanders
@Ned17Flanders · X

RT @VanceE: https://t.co/mUtN6FyFef

Apr 13, 2025 · 1 share · 4,553 followers View post →
Vance
@VanceE · X

https://t.co/mUtN6FyFef

Apr 13, 2025 · 8 likes · 1 share · 42,905 followers View post →
Addi Lhou
@LhouAddi · X

@EatcatAlf @Virginie2R @chimilyne Tu veux les liens ? La flemme mais ok. Y’aura pas tout parce que merde mais voilà : 1. https://t.co/uLsW5Nyx2H 2. https://t.co/L4KRaCUZm6 3. https://t.co/5npLkOYrG7 4. https://t.co/whJCLKUsR1 5. https://t.co/mlLBDnlVom 6. https://t.co/2OxSGxLkZ3 7.

Feb 16, 2025 · 104 followers View post →
AmericanMama
@2prtygirls · X

@JohnDParody JD, I found a study using MB for Bipolar. I can’t access it because don’t have CNS Drugs or Springer subscription. But apparently very good results were achieved from what I could see from the abstract. https://t.co/oopvpgm8Ot

Feb 13, 2025 · 1 like · 1,587 followers View post →
Mike
@MikeforDJT · X

https://t.co/Q6n4WMkjqA… https://t.co/uHCPDhXb5a And there is much more research showing the positive effect of methylene blue, but sure, go ahead and call it a fad. https://t.co/F1pNStyI4K

Feb 6, 2025 · 1 like · 466 followers View post →
Mike
@MikeforDJT · X

@OG_DrC https://t.co/UEbnk92pJS https://t.co/9m2zU0jlPw And there is much more research showing the positive effect of methylene blue but sure go ahead and call it a fad.

Feb 6, 2025 · 4 likes · 466 followers View post →
AmericanMama
@2prtygirls · X

@ZeeL3003 @JohnDParody I just found this; Methylene Blue in the Treatment of Neuropsychiatric Disorders. I can’t see the full study.

Feb 5, 2025 · 1,587 followers View post →
Fiere d'etre slave...
@SvetLan81801067 · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Feb 1, 2025 · 5 shares · 150 followers View post →
Marylouve
@Jeannemarie1309 · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jan 31, 2025 · 5 shares · 3,446 followers View post →
Ella
@Ellacoccinera · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jan 31, 2025 · 5 shares · 1,203 followers View post →
Heather
@hswymeler · X

Methylene Blue has the power to change the love of people with Bipolar. Here is a great brief place to start but the rabbit hole is deep and what I have witnessed was a miracle in my family. https://t.co/Bkl5F17Rg0

Nov 26, 2024 · 1 like · 246 followers View post →
AngryIrishman
@TheGoodKing4All · X

If you do not know about this. You might want to investigate this! https://t.co/ODLHIZ4HJS

Aug 24, 2024 · 1 like · 259 followers View post →
lily
@dylanesqu · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jul 24, 2024 · 8 shares · 1,102 followers View post →
Tracey
@TraceyN02015171 · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jul 15, 2024 · 8 shares · 8,006 followers View post →
isabelle david
@Dpisabelle · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jul 10, 2024 · 5 shares · 785 followers View post →
Kyrekos
@RedbullRacist · X

@SanguisAxis If you are depressed it will likely help, it has helped in cases where antidepressants have not worked: https://t.co/7gaqYEd5tE.

Jul 9, 2024 · 1 like · 1,332 followers View post →
Iveline@iveline
@HLubineau47217 · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jul 9, 2024 · 5 shares · 3 followers View post →
Nas Nas
@nnas68141 · X

RT @vitalholis: 1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jul 9, 2024 · 5 shares · 61 followers View post →
Vitalholis
@vitalholis · X

1 : https://t.co/d2BIHs7fVR 2 : https://t.co/nuQkrQYJvI 3 : https://t.co/80g5fGXLob 4 : https://t.co/6c3iw57smR

Jul 9, 2024 · 12 likes · 5 shares · 19,150 followers View post →
Orioso de Rohars
@Orioso_Rohars · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jun 28, 2024 · 8 shares · 415 followers View post →
Conservative Mom
@hy052981 · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jun 28, 2024 · 8 shares · 2,272 followers View post →
Graphtoverse☦️
@HYPERCYCLEBULL · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jun 28, 2024 · 8 shares · 426 followers View post →
RIFT
@RIFT_589 · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jun 28, 2024 · 8 shares · 4,313 followers View post →
Jeaner
@jeaner08 · X

RT @VanceE: Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene…

Jun 28, 2024 · 8 shares · 2,622 followers View post →
Vance
@VanceE · X

Methylene Blue for Bipolar Disorder. And guess what? An actual study showing benefits long-term. “Long-term use of methylene blue in bipolar disorder led to a better stabilization and a reduction in residual symptoms of the illness.” https://t.co/mUtN6FyFef

Jun 28, 2024 · 53 likes · 8 shares · 42,905 followers View post →
SpaceFromGreece
@SpaceFromGreece · X

Methylene Blue in the Treatment of Neuropsychiatric Disorders - PubMed https://t.co/bgI5AVWOgT

Jun 5, 2024 · 3,936 followers View post →
Söcial Jûstice Necrömånt
@sophia111188 · X

@svoyza @letopisi_rus Про вторую есть хотя бы обзор на Пабмеде https://t.co/CeqHY4gzTV

May 27, 2024 · 1 like · 557 followers View post →
Dylan Dean
@dylandean186 · X

@ryanburrill72 @rafdelafuente @VanceE @Merakimedicinal Yup this stuff. Just search methylene blue medical studies. https://t.co/n2ENzdAryR https://t.co/jCeq46q91F https://t.co/Tt1t0rxxdU https://t.co/SycYYGLyAw

Feb 26, 2024 · 3 likes · 1,808 followers View post →
futuresounds
@futuresoundz369 · X

@ReasonJim @VanceE https://t.co/A6pqcm0GxB

Jan 27, 2024 · 62 followers View post →
Sapha bee
@trumpjustshot · X

@DrewsElJefe Methylene blue has been shown to antidepressant, anxiolytic, and neuroprotective properties documented by both animal and human studies. Source: https://t.co/fNhTdCGU74

Jan 10, 2024 · 15 followers View post →
JoeyS
@Joe1981777 · X

@FilmandTVMania @Gmwetz Isn´t MB antidepressant itself? https://t.co/EWiB9ZDm3N

Dec 23, 2023 · 1 like · 142 followers View post →
BasedBasse
@BasedBasse · X

Improv in memory (djur-studie) https://t.co/2el8iBcJh2 Against Alzheimer's https://t.co/bOr1nqGUq4 Neuropsychiatric benefits of MB https://t.co/xkHWayXYnP… MB fighting depression https://t.co/BYdppQ0y42 Combatting neuroinflammation …https://t.co/wsUWVTysjy…

Dec 1, 2023 · 2,981 followers View post →
a female Faust
@femalefaust · X

@khiazmos looks ok. one caveat: watch out its an MAO inhibitor. stay away from aged cheeses, etc. (look up MAO inhibitor). screenshot below is from see https://t.co/VTOwXadHKl https://t.co/DaNFT2wBIp

Aug 12, 2023 · 1 like · 659 followers View post →
Adelgary
@Adelgary · X

@marjobservation https://t.co/iamxhecVhR

Jul 30, 2023 · 7,831 followers View post →
Ioannis — AI/acc
@kourouklides · X

RT @WilliamHalden: @Fynnderella1 @MdBreathe @RobertKennedyJr antidepressants' efficacy is very questionable—Big Pharma hid some unfavorable…

Jun 6, 2023 · 1 share · 3,174 followers View post →
William Halden MD
@WilliamHalden · X

@MdBreathe @RobertKennedyJr antidepressants' efficacy is very questionable—Big Pharma hid some unfavorable data about them: https://t.co/EwSlp3YDDk And there may be better natural or cheaper alternatives that are not patentable by Big Pharma: https://t.co/sImQs40Sl2 https://t.co/9kPKyANb5C

Jun 5, 2023 · 762 followers View post →
William Halden MD
@WilliamHalden · X

@Fynnderella1 @MdBreathe @RobertKennedyJr antidepressants' efficacy is very questionable—Big Pharma hid some unfavorable data about them: https://t.co/EwSlp3YDDk And there may be better natural or cheaper alternatives that are not patentable by Big Pharma: https://t.co/sImQs40Sl2 https://t.co/9kPKyANb5C

Jun 5, 2023 · 9 likes · 1 share · 762 followers View post →
CJ Jenkins
@stage7 · X

Brain Boosting Methylene Blue || Benefits, Dosing, & Side Effects https://t.co/y0ma2TV43F via @YouTube

Apr 29, 2023 · 399 followers View post →
JustinAnthony
@JustinA10650720 · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 16, 2023 · 6 shares · 509 followers View post →
Golem
@redox_asea77175 · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 12, 2023 · 6 shares · 13 followers View post →
Anahi Campos
@camposanahi · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 12, 2023 · 6 shares · 124 followers View post →
Likepiterathome
@likepiterathome · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 11, 2023 · 6 shares · 276 followers View post →
Joan
@joan_sellares · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 11, 2023 · 6 shares · 208 followers View post →
fausto heredia z.
@drfherediaz · X

RT @mitokondriac: @heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as agin…

Apr 11, 2023 · 6 shares · 4,359 followers View post →
☀️MitoHacker☀️
@mitokondriac · X

@heniek_htw @ChrisPalmerMD @hubermanlab @UCCpsychiatry @MitochondriaNe1 Thanks @heniek_htw Most diseases, as well as aging, are consequence of the energy loss and its related inflamation. Reminder: Methylene blue helps with "mitochondrial fitness". Good, save and cheap. https://t.co/nD8thAhSw3

Apr 11, 2023 · 22 likes · 6 shares · 22,122 followers View post →
Marcello Brello
@molobrain · X

RT @molobrain: @whereisdaz Here’s a snippet from another interesting paper: “In psychiatry, methylene blue has been used for over a century…

Dec 9, 2022 · 1 share · 97 followers View post →
Marcello Brello
@molobrain · X

@whereisdaz Here’s a snippet from another interesting paper: “In psychiatry, methylene blue has been used for over a century. It was tried successfully in the treatment of psychotic and mood disorders and as a memory enhancer in fear-extinction training.” https://t.co/TYuVmh2YLJ

Dec 9, 2022 · 1 share · 97 followers View post →
UltimApe
@ultimape · X

"Long-term use of methylene blue in bipolar disorder led to a better stabilization and a reduction in residual symptoms of the illness. It is usually well tolerated, but caution is needed in the light of its inhibitory effect on monoamine oxidase A." https://t.co/ezm5zt0urb

Sep 23, 2022 · 6,475 followers View post →
川面梵児
@hitukishinji · X

RT @Alzhacker: https://t.co/07dNdXjAg3 メチレンブルーには多数の生化学的作用があり、これらのどれかを特定の臨床作用と関連付けることは容易ではない。この点では,単一の生化学的経路に限定されない複雑な薬理作用を有している。しかし、どちらも現在の…

Sep 18, 2021 · 3 shares · 2,667 followers View post →
Alzhacker
@Alzhacker · X

https://t.co/07dNdXjAg3 メチレンブルーには多数の生化学的作用があり、これらのどれかを特定の臨床作用と関連付けることは容易ではない。この点では,単一の生化学的経路に限定されない複雑な薬理作用を有している。しかし、どちらも現在の精神医学において最も効果的な薬の一つである。

Sep 18, 2021 · 30 likes · 3 shares · 32,859 followers View post →
Elizabeth Aileen Mol
@BethEAMM · X

Methylene Blue in the Treatment of Neuropsychiatric Disorders. - PubMed - NCBI https://t.co/97cenUaedd

Feb 13, 2020 · 16 followers View post →
P
@psychopharmacol · X

In psychiatry, methylene blue has been used for over a century. It was tried successfully in the treatment of psychotic and mood disorders. Particularly promising results have been obtained in both short- and long-term treatment of bipolar disorder https://t.co/fL1Ob7zPBP

Aug 9, 2019 · 575 followers View post →