PubHawk
F1000Res June 2020 PMID 31316753

mTOR as a central regulator of lifespan and aging.

David Papadopoli, Karine Boulay, Lawrence Kazak, Michael Pollak, Frédérick A Mallette, Ivan Topisirovic, Laura Hulea

Download social card

Mentions

83
Peak: 22 in Aug 2019
across 5 sources since Jul 2019

Extended reach

165,886
potential audience

Total likes

361

Video views

10,127

Mentions per month

Jul 2019 – Aug 2025

Where it's discussed

  • News40 articles
  • X / Twitter33 posts
  • Blogs5 articles
  • Facebook3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The group’s discussions consistently praise the role of mTOR in aging, with examples like mentions of rapamycin as an inhibitory agent, references to animal studies, and suggestions to start inhibiting mTOR early through diet or drugs. The tone is enthusiastic and exploratory, reflecting a strong belief in the significance of this research for future health improvements.

AgreementStrong agreement

Most discussions agree that mTOR is key in regulating lifespan and aging, highlighting the significance of the research, often emphasizing rapamycin’s role and its potential benefits.

InterestHigh interest

The discussions demonstrate high interest, with many users sharing enthusiasm, references to reviews, and speculation about applying these findings, indicating active curiosity.

EngagementHigh engagement

Participants delve into detailed topics like mechanisms of mTOR, animal trials, and potential human applications, showing deep engagement and familiarity with the subject.

ImpactHigh impact

Given the focus on lifespan extension and aging processes, the discussions suggest this research could have profound implications on future therapies and aging science, indicating high impact.

Top posts

Most liked on X and Bluesky
Aging Science News
@AgingBiology · X

mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 40 likes · 18 shares · 30,517 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Microbes activate mTOR, which additionally suggests their role on aging and lifespan: https://t.co/RUvJJrOUnF mTOR as a central regulator of lifespan and aging. https://t.co/AHtqsktDrP

Aug 3, 2019 · 5 likes · 9,731 followers View post →
Paul Razvan Berg
@PaulRBerg · X

@MicahZoltu @Blagosklonny @RapaNews Consequently, you might just want to start inhibiting mTOR today rather than wait a few decades, and rapamycin is the easiest way to do it now. Prolonged fasting is another option, but that is certainly not enjoyable. 2/2 https://t.co/5aZ5ICVwLE

Dec 28, 2022 · 2 likes · 20,608 followers View post →
Lifeboat Foundation
@LifeboatHQ · X

mTOR as a central regulator of lifespan and aging https://t.co/DWGUICo6KB https://t.co/URLOQyNcBC

Aug 4, 2019 · 1 like · 2 shares · 31,597 followers View post →
Juan Carlos Gonzalez
@hepatopatias · X

F1000Research Article: mTOR as a central regulator of lifespan and aging. https://t.co/HHr0C6Ac8s

Aug 3, 2019 · 1 like · 628 followers View post →
Paul Razvan Berg
@PaulRBerg · X

@bigbottlebrush These are early days as far as human trials for rapamycin go. However, the animal research is very promising, and broadly speaking the explanation of why rapamycin works is beautiful. That is, mTOR being the central regulator of lifespan and aging. https://t.co/5aZ5ICW4Bc

Nov 30, 2022 · 20,608 followers View post →

All mentions

星の生まれる丘から
@don_ramiro10 · X

mTOR as a central regulator of lifespan and aging https://t.co/TxY43lKTb7

Aug 30, 2025 · 841 followers View post →
EverNewEcoN
@evernewecon · X

https://t.co/4XAZriDnAG Negative Master Regulator https://t.co/4XAZriDnAG https://t.co/5KG4DzOKa1 mTOR as a central regulator of lifespan and aging Suppressed by rapamycin https://t.co/0I8qgEcwW9 Blocked by nagalase -sa-

Jul 13, 2025 · 698 followers View post →
EverNewEcoN
@evernewecon · X

https://t.co/kXR1Pob6o9 Negative Master Regulator https://t.co/4XAZriDnAG https://t.co/5KG4DzOKa1 mTOR as a central regulator of lifespan and aging Suppressed by rapamycin https://t.co/0I8qgEcwW9 Blocked by nagalase /p

Jul 13, 2025 · 698 followers View post →
EverNewEcoN
@evernewecon · X

RT @evernewecon: https://t.co/BhpIPCGA69 Negative Master Regulator https://t.co/BhpIPCGA69 https://t.co/5KG4DzOKa1 mTOR as a central regula…

Dec 28, 2024 · 1 share · 698 followers View post →
EverNewEcoN
@evernewecon · X

https://t.co/BhpIPCGA69 Negative Master Regulator https://t.co/BhpIPCGA69 https://t.co/5KG4DzOKa1 mTOR as a central regulator of lifespan and aging Suppressed by rapamycin https://t.co/0I8qgEcwW9 Blocked by nagalase https://t.co/mFo26oZx8Z

Dec 15, 2024 · 1 share · 698 followers View post →
Paul Razvan Berg
@PaulRBerg · X

@MicahZoltu @Blagosklonny @RapaNews Consequently, you might just want to start inhibiting mTOR today rather than wait a few decades, and rapamycin is the easiest way to do it now. Prolonged fasting is another option, but that is certainly not enjoyable. 2/2 https://t.co/5aZ5ICVwLE

Dec 28, 2022 · 2 likes · 20,608 followers View post →
Paul Razvan Berg
@PaulRBerg · X

@bigbottlebrush These are early days as far as human trials for rapamycin go. However, the animal research is very promising, and broadly speaking the explanation of why rapamycin works is beautiful. That is, mTOR being the central regulator of lifespan and aging. https://t.co/5aZ5ICW4Bc

Nov 30, 2022 · 20,608 followers View post →
France Legare
@SDM_ULAVAL · X

Bravo @LauraHulea CLub de recherches cliniques du Québec https://t.co/Ve7bB87n1k

Sep 30, 2022 · 3,068 followers View post →
Richard Harper
@harpersnotes · X

(if anyone feels like nerding out more than I do, a 2019 mTOR review, "mTOR as a central regulator of lifespan and aging" .. or maybe I'll get motivated later.) https://t.co/WmaDA5QPNT ..

Apr 11, 2022 · 2,236 followers View post →
Gretchen Dorn
@gdorn1 · X

RT @LifeboatHQ: mTOR as a central regulator of lifespan and aging https://t.co/DWGUICo6KB https://t.co/URLOQyNcBC

Aug 4, 2019 · 2 shares · 6,338 followers View post →
Eva Latorre
@DrELatorre · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 336 followers View post →
mehdi heidari
@mehdiheidari11 · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 85 followers View post →
annibal_ms
@AnnibalMs · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 304 followers View post →
Jamie Timmons
@metapredict · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 2,056 followers View post →
Europe-SFRR
@SFRR_Europe · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 954 followers View post →
Lifeboat Foundation
@LifeboatHQ · X

mTOR as a central regulator of lifespan and aging https://t.co/DWGUICo6KB https://t.co/URLOQyNcBC

Aug 4, 2019 · 1 like · 2 shares · 31,597 followers View post →
Reza Dorvash
@DorvashMR · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 4, 2019 · 18 shares · 409 followers View post →
juice like
@Bactosafe · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 39 followers View post →
George Vlasuk
@GVlasuk · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 1,425 followers View post →
dr.yusipova_official
@DrYusipova · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 89 followers View post →
humanOS.me
@humanOS_me · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 9,662 followers View post →
Collin Ewald
@CollinEwald · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 4,536 followers View post →
SNZK
@shinopp · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 720 followers View post →
Theptat
@Theptat5 · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 15 followers View post →
Jose R. Blanco
@jrblanco11 · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 573 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Microbes activate mTOR, which additionally suggests their role on aging and lifespan: https://t.co/RUvJJrOUnF mTOR as a central regulator of lifespan and aging. https://t.co/AHtqsktDrP

Aug 3, 2019 · 5 likes · 9,731 followers View post →
catallaxer
@catallaxer · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 803 followers View post →
paul_taik
@paul_taik · X

F1000Research Article: mTOR as a central regulator of lifespan and aging. https://t.co/G6L5WcuN2n

Aug 3, 2019 · 20 followers View post →
Juan Carlos Gonzalez
@hepatopatias · X

F1000Research Article: mTOR as a central regulator of lifespan and aging. https://t.co/HHr0C6Ac8s

Aug 3, 2019 · 1 like · 628 followers View post →
AntiAgify - Science will set you free
@AntiAgify · X

RT @AgingBiology: mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 18 shares · 1,355 followers View post →
Aging Science News
@AgingBiology · X

mTOR as a central regulator of lifespan and aging. https://t.co/ofmhDirXBL

Aug 3, 2019 · 40 likes · 18 shares · 30,517 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

mTOR as a central regulator of lifespan and aging. https://t.co/tHojt0G6Qs

Jul 19, 2019 · 2,241 followers View post →
Brian Chutskoff CD MD FRCSC (ret’d)
@BrianChutskoff · X

#Ageing mTOR as a central regulator of lifespan and aging | F1000Research https://t.co/YglLcpJoie

Jul 4, 2019 · 550 followers View post →