Science August 2019 PMID 31371612

3D bioprinting of collagen to rebuild components of the human heart.

A Lee, A R Hudson, D J Shiwarski, J W Tashman, T J Hinton, S Yerneni, J M Bliley, P G Campbell, A W Feinberg

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200

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The discussions highlight key advancements, such as the high-resolution capabilities of the FRESH bioprinting technique, which allows for the creation of functional heart tissues. Phrases like 'game changer' and references to using this technology for drug testing underscore the importance of these developments in reshaping healthcare practices.

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Participants demonstrate a high level of curiosity and enthusiasm regarding the advancements detailed in the article.

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Many posts delve into specific techniques and their implications for healthcare and tissue engineering, indicating a deep engagement with the material.

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Contributors believe that the publication could have significant implications for medical science, particularly in regenerative medicine and cardiac repairs.

Abstract in brief

3D bioprinting techniques allow for the fabrication of collagen scaffolds that mimic human heart structures, overcoming previous challenges in tissue engineering.
The innovative FRESH (Freeform Reversible Embedding of Suspended Hydrogels) method achieves high precision (20 micrometers) and enhances features like microvascularization and mechanical strength in the printed components.
The study demonstrates that 3D-printed heart tissues not only replicate patient-specific anatomy but also exhibit functional properties like synchronized contractions and action potential propagation, important for heart performance.

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All mentions

Fluorescent Dextran Perfusion in 3D Bioprinted Collagen Tubes

This video demonstrates the perfusion of 10 kDa fluorescent dextran through a collagen tube. The peristaltic flow is shown in a high-resolution format, enhancing our understanding of 3D bioprinting techniques in heart…

Feinberg Regenerative Biomaterials Group · Apr 13, 2020 68 views

Understanding Bioprinting and Its Impact on Cardiac Tissue Engineering

Want to understand the value of bioprinters? This video explores how 3D bioprinting techniques enable the fabrication of collagen scaffolds that replicate human heart structures, enhancing features like…

Business of Bioprinting · Aug 30, 2024 18 views

FluidForm Bio

@FluidFormBio · X

Still casting #collagen? Read about how #FRESH #bioprinting with #LifeSupport (https://t.co/qdbbQgAOHu) enables the #3Dbioprinting of #collagen to improve cellular infiltration and vascularization! @RegenBio's Science Paper: https://t.co/qVrbcFgU9z https://t.co/lMNDSGS1ml

Apr 20, 2022 · 2 likes · 476 followers View post →

FluidForm Bio

@FluidFormBio · X

Jan 31, 2022 · 5 likes · 1 share · 476 followers View post →

T.J. Hinton

@7JHinton · X

RT @FluidForm3D: You don’t need to #bioprint logpiles anymore. Print exactly what you want without compromise by using #LifeSupport to #FRE…

Jan 28, 2022 · 1 share · 27 followers View post →

FluidForm Bio

@FluidFormBio · X

You don’t need to #bioprint logpiles anymore. Print exactly what you want without compromise by using #LifeSupport to #FRESH bioprint at higher resolution. LifeSupport: https://t.co/1Gh3lyEwBO @RegenBio's Science Paper: https://t.co/LIwyHzVLdQ https://t.co/hytywQkBlo

Jan 28, 2022 · 4 likes · 1 share · 476 followers View post →

FluidForm Bio

@FluidFormBio · X

Jan 17, 2022 · 3 likes · 476 followers View post →

FluidForm Bio

@FluidFormBio · X

Jan 14, 2022 · 3 likes · 476 followers View post →

Faaz Ashraf

@faazash · X

RT @AdditionalVent: (1/2) In work led by #AVSpotlight @Andrew_Hudson3D & @AndrewLee3dp the @RegenBio team developed an embedded printing ap…

Nov 16, 2021 · 2 shares · 233 followers View post →

Jacqueline Bliley

@HijackSciJac · X

RT @AdditionalVent: (1/2) In work led by #AVSpotlight @Andrew_Hudson3D & @AndrewLee3dp the @RegenBio team developed an embedded printing ap…

Nov 15, 2021 · 2 shares · 91 followers View post →

Additional Ventures

@AdditionalVent · X

(1/2) In work led by #AVSpotlight @Andrew_Hudson3D & @AndrewLee3dp the @RegenBio team developed an embedded printing approach that revolutionized #3Dbioprinting of soft biological materials like type I collagen with high resolution. https://t.co/gjnJSDqTuz

Nov 15, 2021 · 3 likes · 2 shares · 905 followers View post →

Mark Allenby

@MCAllenby · X

RT @FluidForm3D: #FRESH allows for bioprinting cellular inks (300 million+ cells/mL), shown in this Science paper (https://t.co/qVrbcFgU9z)…

Nov 4, 2021 · 5 shares · 1,430 followers View post →

Mike Gee

@mikegeecmu · X

RT @FluidForm3D: #FRESH allows for bioprinting cellular inks (300 million+ cells/mL), shown in this Science paper (https://t.co/qVrbcFgU9z)…

Nov 3, 2021 · 5 shares · 843 followers View post →

CMU_BME

@cmu_bme · X

RT @FluidForm3D: #FRESH allows for bioprinting cellular inks (300 million+ cells/mL), shown in this Science paper (https://t.co/qVrbcFgU9z)…

Nov 3, 2021 · 5 shares · 1,212 followers View post →

3DHEALS

@3dheals · X

RT @FluidForm3D: #FRESH allows for bioprinting cellular inks (300 million+ cells/mL), shown in this Science paper (https://t.co/qVrbcFgU9z)…

Nov 2, 2021 · 5 shares · 5,022 followers View post →

T.J. Hinton

@7JHinton · X

RT @FluidForm3D: #FRESH allows for bioprinting cellular inks (300 million+ cells/mL), shown in this Science paper (https://t.co/qVrbcFgU9z)…

Nov 2, 2021 · 5 shares · 27 followers View post →

FluidForm Bio

@FluidFormBio · X

Nov 2, 2021 · 14 likes · 5 shares · 476 followers View post →

Jacqueline Bliley

@HijackSciJac · X

RT @AdditionalVent: The seminal paper @ScienceMagazine by @RegenBio & #AVSpotlight @HijackSciJac established a technique to bioprint collag…

Sep 22, 2021 · 1 share · 91 followers View post →

Additional Ventures

@AdditionalVent · X

The seminal paper @ScienceMagazine by @RegenBio & #AVSpotlight @HijackSciJac established a technique to bioprint collagen, cardiomyocytes & fibroblasts with high res & showed that it can be used to engineer valves, ventricles & even whole hearts https://t.co/IIOzhmEMcP

Sep 21, 2021 · 1 share · 905 followers View post →

Ting-Wei Lin

@TingWeiLinMD · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/5czIw87eMo

Nov 25, 2020 · 1 like · 103 followers View post →

Science In Vitro

@ScienceInVitro · X

RT @ImagingOrg: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/8d4Tnfr76M #bioprinting #cardiology #stemc…

Aug 5, 2020 · 1 share · 208 followers View post →

IMGGE

@IMGGE · X

ZANIMLJIVOSTI MOLEKULARNE 2019: Istraživači su objavili detalje nove tehnike za 3D bioštampanje struktura od kolagena, glavnog strukturnog proteina u ljudskom telu. https://t.co/ccXfeMNVCD . https://t.co/IicTrv36tx T: +381 11 3975744 info@imgge.bg.ac.rs . #IMGGI #Institut https://t.co/MjWJHjqgD7

May 26, 2020 · 1 like · 241 followers View post →

Indulekha Pillai

@PillaiIndulekha · X

RT @sojasagharsoman: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/INTuuvTBhr

Feb 15, 2020 · 1 share · 265 followers View post →

soja saghar soman

@sojasagharsoman · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/INTuuvTBhr

Feb 15, 2020 · 1 like · 1 share · 110 followers View post →

Alan Altmann

@aaltmann · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/NJih9TuJ7E

Feb 14, 2020 · 650 followers View post →

IS&T

@ImagingOrg · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/8d4Tnfr76M #3dprinting #bioprinting #cardiology

Feb 6, 2020 · 2 likes · 2,167 followers View post →

Elaine Soohoo, PhD

@sososoohoo · X

#1: Freeform reversible embedding of suspended hydrogels (FRESH v2.0) 3D-bioprinting of perfusable μ-vasculature, ventricles, & tri-leaflet valve collagen scaffolds cultured with cells demonstrated structural, mech, & biological properties of heart https://t.co/1Moh1yDi7e 1/250

Jan 7, 2020 · 236 followers View post →

garigalAnj

@garigalAnj · X

RT @YuSukChoi: Super cool paper from Andrew Lee (ex Engler lab) from Adam Feinberg lab!!! 3D bioprinting of collagen to rebuild components…

Oct 30, 2019 · 2 shares · 2,372 followers View post →

Kursad Turksen

@kursadturksen · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/pCyYmmGsOj

Oct 21, 2019 · 228 followers View post →

Adam Lauver, PhD

@dalauver · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/ppI1TQTxqd

Oct 10, 2019 · 1,024 followers View post →

Dan Shiwarski, Ph.D.

@ShiwarskiLab · X

Andrew Hudson,@AndrewLee3dp,and @RegenBio have their @905wesa NPR debut discussing our work on "3D bioprinting of collagen to rebuild components of the human heart" in @sciencemagazine @cmu_bme. Great job guys! #FRESHprinting https://t.co/Ia3QJPWDGg, https://t.co/ID6nJuyNWT

Sep 4, 2019 · 3 likes · 155 followers View post →

マーキュリー２世

@uranus_2 · X

コラーゲンを使った、ヒトの心臓構成の3Dバイオプリンティング。3D bioprinting of collagen to rebuild components of the human heart https://t.co/efPxAjKkzL

Aug 19, 2019 · 5,526 followers View post →

Frank Meunier

@Frank_Meunier · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/Akfc6cgQOc

Aug 12, 2019 · 648 followers View post →

Marco Sorbona

@MSorbona · X

A step closer to "mend a broken heart" 3D bioprinting of collagen to rebuild components of the human heart Great work by the @RegenBio group. https://t.co/FHQnWA6UFA

Aug 12, 2019 · 3 likes · 296 followers View post →

Sam Rhine

@samrhineguc · X

- Note from Sam - 3D bioprinting of collagen to rebuild components of the human heart https://t.co/YTAgcA65zP

Aug 10, 2019 · 4 likes · 783 followers View post →

Siegfried Treitner

@TreitnerS · X

https://t.co/czp6B4IWgz "#3D #bioprinting of #collagen to rebuild components of the #human #heart"

Aug 9, 2019 · 2,121 followers View post →

KuniTsum

@92tsumo · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/WmRdjzG6VX

Aug 8, 2019 · 5 followers View post →

Bʜᴀɢɪʀᴀᴛʜ Kᴜᴍᴀʀ Lᴀᴅᴇʀ

@bhagirathl · X

3D bioprinting of collagen to rebuild components of the human heart #3dprint #heart #healthtech #healthcareindustry https://t.co/APJqqFBdqa

Aug 8, 2019 · 842 followers View post →

TheTweetOfRhea

@TheTweetOfRhea · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/mTIJWGHS78

Aug 7, 2019 · 44,240 followers View post →

Ting-Wei Lin

@TingWeiLinMD · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/5czIw87eMo

Aug 7, 2019 · 103 followers View post →

Iris Rguez Costoya

@irisRcostoya · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 5, 2019 · 10 shares · 277 followers View post →

Mike

@3Dprint_Seattle · X

3D bioprinting of collagen to rebuild components of the human heart - 3deinc: For biofabrication, the goal is to engineer tissue scaffolds to treat diseases for which there are limited options, such as end-stage organ failure. Three-dimensional... https://t.co/3XF9sr3K2T

Aug 5, 2019 · 4,927 followers View post →

Biz Comm Strategies

@BCstrat · X

RT @evankirstel: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/EL4QZAJtVM #HealthTech

Aug 5, 2019 · 3 shares · 37,574 followers View post →

Science

@Long_life_sci · X

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Aug 5, 2019 · 32 followers View post →

Alec Pettifer

@alecpett · X

RT @evankirstel: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/EL4QZAJtVM #HealthTech

Aug 5, 2019 · 3 shares · 2,417 followers View post →

Sayem Khan

@Sayem_khan_2101 · X

RT @evankirstel: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/EL4QZAJtVM #HealthTech

Aug 5, 2019 · 3 shares · 2,709 followers View post →

Evan Kirstel #B2B #TechFluencer

@EvanKirstel · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/EL4QZAJtVM #HealthTech

Aug 5, 2019 · 5 likes · 3 shares · 375,010 followers View post →

部谷直亮

@a2ad_nh · X

RT @gelmitsu: カーネギーメロン大学の研究。サイエンスに掲載されています。3D bioprinting of collagen to rebuild components of the human heart | Science https://t.co/jZcNA…

Aug 4, 2019 · 1 share · 5,754 followers View post →

古川英光（Hidemitsu Furukawa）｜現代ソフトマター学

@gelmitsu · X

Aug 4, 2019 · 8 likes · 1 share · 1,940 followers View post →

Julieta Rossi Pedrosa ✝️

@julieta_pedrosa · X

#3D bioprinting of collagen to rebuild components of the human #heart https://t.co/zYcoOdn5w3 #Science #technology

Aug 3, 2019 · 1 like · 2,880 followers View post →

#WikiParty@michaelgraaf@cheeseburger.social

@michaelgraaf · X

RT @GerdMoeBehrens: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/1FBYikV07T

Aug 3, 2019 · 1 share · 634 followers View post →

Krishnakumar k

@Krishna69026264 · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 3, 2019 · 10 shares · 61 followers View post →

matiere*

@matiere · X

3D bioprinting of collagen to rebuild components of the human heart | Science https://t.co/q9OEqRdTKf

Aug 3, 2019 · 2,850 followers View post →

Dr Avik Sarker

@avik_sarker · X

RT @saber_yavari: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/1pG3cklryf

Aug 2, 2019 · 1 share · 253 followers View post →

Pau Puigdevall (paupuigdevall@bsky.social)

@paupuigdevall · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/lzMtMSyIoz

Aug 2, 2019 · 1 like · 616 followers View post →

Dabit Arzamendi

@StructuralBCN · X

RT @DavidVilades: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/XzlOBIBuWT @AMoustafa_MD @CardioBCN @Str…

Aug 2, 2019 · 2 shares · 2,255 followers View post →

Gerd Moe-Behrens

@GerdMoeBehrens · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/1FBYikV07T

Aug 2, 2019 · 1 like · 1 share · 2,453 followers View post →

Alessandra Joslin

@AleJoslin · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 2, 2019 · 10 shares · 419 followers View post →

David Viladés

@DavidVilades · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/XzlOBIBuWT @AMoustafa_MD @CardioBCN @StructuralBCN

Aug 2, 2019 · 8 likes · 2 shares · 626 followers View post →

Joe Gordon

@josephwgordon · X

RT @NatRevCardiol: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/iRoeCkDJ72

Aug 2, 2019 · 2 shares · 2,110 followers View post →

Colegio Andrés Bello

@Colegio_AB · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/kdAcPqgqPO

Aug 2, 2019 · 7 followers View post →

Science Furs

@Sci_Furs · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/8gIcYANDKY

Aug 2, 2019 · 2 likes · 2,279 followers View post →

RESTORE

@RESTOREhorizon · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/PTTk2iC4PV

Aug 2, 2019 · 390 followers View post →

Alain BERREBI

@bibi0562 · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 2, 2019 · 10 shares · 937 followers View post →

Ken Gusler

@kgusler · X

3D bioprinting of collagen to rebuild components of the human heart - https://t.co/Tm23TvzXDF

Aug 2, 2019 · 20,018 followers View post →

ثامر بن نواف بن يوسف السعدون

@Thamerzo6 · X

RT @DRKAMALAYOUB: تقنية جديدة لطباعة الانسجة بالابعاد الثلاثية تعد بانتاج اعضاء بشرية حسب الطلب . https://t.co/VLrZSYgoOS https://t.co/BTtF…

Aug 2, 2019 · 4 shares · 1,927 followers View post →

Naser

@kenon999 · X

Aug 2, 2019 · 4 shares · 132 followers View post →

Daniele Catalucci

@DCatalucci · X

3D bioprinting of collagen to rebuild components of the human heart | Science https://t.co/HDaNygJbo4

Aug 2, 2019 · 373 followers View post →

Nature Reviews Cardiology

@NatRevCardiol · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/iRoeCkDJ72

Aug 2, 2019 · 5 likes · 2 shares · 20,407 followers View post →

د. هاني سفر الغامدي | Dr. Hani S Alghamdi

@dr_hani_s · X

Aug 2, 2019 · 4 shares · 9,358 followers View post →

Dr Ihab Suliman

@IhabFathiSulima · X

Aug 2, 2019 · 4 shares · 89,164 followers View post →

الدكتور كمال أيوب

@DRKAMALAYOUB · X

تقنية جديدة لطباعة الانسجة بالابعاد الثلاثية تعد بانتاج اعضاء بشرية حسب الطلب . https://t.co/VLrZSYgoOS https://t.co/BTtFMsgQUE

Aug 2, 2019 · 7 likes · 4 shares · 24,070 followers View post →

Julien Magne

@jumagne · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 2, 2019 · 10 shares · 344 followers View post →

Ioana

@fata_dragonului · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/xo68B4ACLm

Aug 2, 2019 · 403 followers View post →

PIER MARIA FORNASARI

@PierFornasari · X

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Aug 2, 2019 · 325 followers View post →

Saber Amin Yavari

@saber_yavari · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/1pG3cklryf

Aug 2, 2019 · 4 likes · 1 share · 194 followers View post →

Alex Vazquez

@AVazquezMD · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 2, 2019 · 10 shares · 313 followers View post →

Kristopher Kilian

@KrisKilian · X

Aug 2, 2019 · 12 likes · 2,609 followers View post →

Joe Doyle

@Rocket2010 · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 2, 2019 · 10 shares · 321 followers View post →

Mechanobiology @ UCT

@mechanobiol_uct · X

RT @YuSukChoi: Super cool paper from Andrew Lee (ex Engler lab) from Adam Feinberg lab!!! 3D bioprinting of collagen to rebuild components…

Aug 2, 2019 · 2 shares · 604 followers View post →

Yu Suk CHOI

@YuSukChoi · X

Super cool paper from Andrew Lee (ex Engler lab) from Adam Feinberg lab!!! 3D bioprinting of collagen to rebuild components of the human heart https://t.co/LxXYju5MhP @AdamEnglerUCSD #proudmentors

Aug 1, 2019 · 3 likes · 2 shares · 1,067 followers View post →

SJC

@MyDailySJCnews · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/qqYpkfy0sx

Aug 1, 2019 · 9 followers View post →

Kato

@oxkawaka · X

3D bioprinting of collagen to rebuild components of the human heart 最近チラホラ見るけど、将来的に大きな分野になるんだろうな https://t.co/weRk4Aswfs

Aug 1, 2019 · 5,822 followers View post →

Mahek Shah, MD

@Cardiobro · X

RT @PPibarot: First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https:…

Aug 1, 2019 · 10 shares · 1,829 followers View post →

Philippe Pibarot

@PPibarot · X

First 3D bioprinting of a cardiac valve! 3D bioprinting of collagen to rebuild components of the human heart | Science https://t.co/gKxgdYZSYd

Aug 1, 2019 · 26 likes · 10 shares · 6,843 followers View post →

Laura Moore

@lauramoore017 · X

RT @3DPrinting_Live: 3D bioprinting of collagen to rebuild components of the human heart https://t.co/7EcvVb2m8A

Aug 1, 2019 · 1 share · 143 followers View post →

3D Printing

@3DPrinting_Live · X

3D bioprinting of collagen to rebuild components of the human heart https://t.co/7EcvVb2m8A

Aug 1, 2019 · 1 share · 1,053 followers View post →

manu

@MRuizHerrera · X

RT @emulenews: 3D bioprinting: a FRESH (freeform reversible embedding of suspended hydrogels) SLATE (stereolithographic apparatus for tissu…

Aug 1, 2019 · 1 share · 877 followers View post →

Francis Villatoro

@emulenews · X

3D bioprinting: a FRESH (freeform reversible embedding of suspended hydrogels) SLATE (stereolithographic apparatus for tissue engineering) https://t.co/za20aRVYi3 3D bioprinting of collagen to rebuild components of the human heart https://t.co/TzZJLF4mSW https://t.co/GyteEaEQgE

Aug 1, 2019 · 4 likes · 1 share · 45,153 followers View post →

3D bioprinting of collagen to rebuild components of the human heart.

Mentions per month

Where it's discussed

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Abstract in brief

Top posts

All mentions

Fluorescent Dextran Perfusion in 3D Bioprinted Collagen Tubes

Understanding Bioprinting and Its Impact on Cardiac Tissue Engineering