August 2019 PMID 31383846

Efficacy of omega-3 PUFAs in depression: A meta-analysis.

Yuhua Liao, Bo Xie, Huimin Zhang, Qian He, Lan Guo, Mehala Subramanieapillai, Beifang Fan, Ciyong Lu, Roger S McIntyre

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Mentions

132

Peak: 8 in Nov 2019

across 5 sources since Aug 2019

Extended reach

976,630

potential audience

Total likes

599

Video views

34,575

Mentions per month

Aug 2019 – Nov 2025

Where it's discussed

News83 articles
X / Twitter34 posts
Facebook8 posts
YouTube4 videos
Blogs3 articles

AI synopsis

What people are saying

The social discussions consistently support the publication's findings, emphasizing EPA's superior efficacy over DHA, with examples like 'EPA-major formulations consistently outperform DHA-major formulations' and references to precise dosages like '1g per day.' Words like 'support' and 'beneficial effects' convey strong agreement and recognition of the study's importance, illustrating moderate to high engagement and impact.

AgreementStrong agreement

Most social discussions support the meta-analysis findings, highlighting EPA's effectiveness in treating depression, with phrases like 'EPA-major formulations outperform DHA' and 'current evidence supports beneficial effects.'

InterestHigh interest

Posts show high interest, referencing specific research results, doses, and clinical implications, such as '1g / day' and 'EPA ≥60%,' indicating engagement with the detailed science.

EngagementModerate engagement

Many discuss study effects and implications, with some referencing multiple studies, emphasizing the importance of EPA, and expressing support, suggesting moderate but meaningful engagement.

ImpactHigh impact

Multiple posts highlight the significance of the research, citing it as a 'game changer' or 'supporting current treatments,' indicating it could influence ongoing debates or clinical practices.

Abstract in brief

This meta-analysis examined the effectiveness of omega-3 fatty acids, especially EPA and DHA, in reducing depression symptoms through reviewing multiple clinical trials, and found that EPA, particularly at a dose of 1 gram per day, has a significant beneficial effect.
The study analyzed data from 26 trials involving 2,160 participants and used various statistical methods to confirm the stability of its findings, showing that EPA formulations were more effective than DHA for treating depression.
Although results support EPA’s benefits, the authors suggest more research is needed to determine how omega-3 supplementation works for different subgroups, especially considering factors like inflammation levels and depression severity.]

Read the full abstract

All mentions

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Omega-3 Fatty Acids and Their Benefits for Eye and Skin Health

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مغالطات علمية · Feb 28, 2022 3,569 views

The Role of Omega-3 in Brain Health and Cognition

Does Omega-3 truly benefit the brain or is it a myth? This video examines recent studies on EPA and DHA related to memory, Alzheimer’s, depression, and anxiety disorders. Discover when Omega-3 is effective and why many…

Dr. Armin Khonsari · Nov 2, 2025 96 views

laden.hl

@eilelemah · X

@jojo_berriz @Chishiki227 ? Suce un arbre toi qui t a dis que tu pouvais venir dans mes mentions https://t.co/kbd3qSrLAy https://t.co/m7jn2VuGoA https://t.co/rVJRjkGT28 https://t.co/ZvMtZ9Sh7l https://t.co/OCid76csIR Je sais pas si tu sais lire l'animal mais au cas où

Sep 13, 2025 · 123 followers View post →

Kille Tölönen

@Neonomide · X

@rps47586 @BrandonLuuMD EPA-major formulations consistently outperform DHA-major formulations in RCTs treating major depression: https://t.co/UYQqkRWEmc Efficacy of omega-3 PUFAs in depression: A meta-analysis - PubMed

Aug 2, 2025 · 1 like · 924 followers View post →

Idealist

@Baltazarland1 · X

@TiredActor https://t.co/kWr8dM6eY6

Jul 9, 2025 · 590 followers View post →

Daniel A. Dourado

@dadourado · X

Peixes e ômega-3: Estudos observacionais sugerem que quem consome mais peixe tem menor risco de depressão. ➡️ Suplementos de ômega-3 mostram efeito modesto em ensaios duplo-cego.

Jun 20, 2025 · 6 likes · 1 share · 108,949 followers View post →

drtakassi

@drtakassi · X

O estudo abaixo mostrou esse impacto diretamente: "Efficacy of omega-3 PUFAs in depression: A meta-analysis" doi: 10.1038/s41398-019-0515-5

Oct 31, 2024 · 7 likes · 13,084 followers View post →

علوم ماجد

@oloommajed · X

@AlasiriMansour أضف إلى ذلك د. منصور أن بعض المواد الغذائية كالأحماض الدهنية للأسماك وَ الزعفران ثبت علمياً أن لها خواص مضادة للإكتئاب .. المصادر : Efficacy of omega-3 PUFAs in depression: A meta-analysis Saffron and major depressive disorder: a meta-analysis of randomized clinical trials

Jul 18, 2023 · 225 followers View post →

علوم ماجد

@oloommajed · X

٣- معظم النتائج الإيجابية على الصحة النفسية ( تحسين المزاج وَ مقاومة الاكتئاب ) كانت عندما بلغت نسبة تركيز ال EPA أكثر من ٦٠٪ و بتركيز يقترب من الجرام الواحد المصدر : Efficacy of omega-3 PUFAs in depression: A meta-analysis https://t.co/icgmrDXaCk

Jun 26, 2023 · 225 followers View post →

علوم ماجد

@oloommajed · X

وجدت الدرسات أن المكملات التي احتوت على تركيز عالي من الحمض الدهني ( EPA ) بنسبة ٦٠٪ فأكثر و بتركيز ١ جم هي التي نجحت في إحداث هذا التأثير الإيجابي المصدر : Efficacy of omega-3 PUFAs in depression: A meta-analysis

Jun 25, 2023 · 225 followers View post →

Milagros Céspedes

@PsicologaMiliCe · X

RT @carlos_arnaud: Cuando un paciente se encuentra diagnosticado con Depresión, puede ser útil en su tratamiento tomar 1 gr de Omega-3 al d…

Sep 8, 2022 · 4 shares · 337 followers View post →

Luis E Zedillo S

@luisezedillo · X

RT @carlos_arnaud: Cuando un paciente se encuentra diagnosticado con Depresión, puede ser útil en su tratamiento tomar 1 gr de Omega-3 al d…

Sep 8, 2022 · 4 shares · 560 followers View post →

Lupita Gonzalez

@lupilloglez03 · X

RT @carlos_arnaud: Cuando un paciente se encuentra diagnosticado con Depresión, puede ser útil en su tratamiento tomar 1 gr de Omega-3 al d…

Sep 8, 2022 · 4 shares · 78 followers View post →

Malkovich

@amvslp · X

RT @carlos_arnaud: Cuando un paciente se encuentra diagnosticado con Depresión, puede ser útil en su tratamiento tomar 1 gr de Omega-3 al d…

Sep 8, 2022 · 4 shares · 550 followers View post →

Dr. Carlos Arnaud

@carlos_arnaud · X

Sep 8, 2022 · 10 likes · 4 shares · 21,243 followers View post →

Simon Hill MSc, BSc

@theproof · X

Efficacy of omega-3 PUFAs in depression: A meta-analysis | Translational Psychiatry https://t.co/zxOa5boGkE

May 9, 2021 · 4 likes · 34,158 followers View post →

Specialist Nutrition Rehab

@SpecialistRD · X

RT @RedPepperNutri: Efficacy of omega-3 PUFAs in depression: A meta-analysis https://t.co/jGy5LIdKxx

Feb 24, 2021 · 2 shares · 534 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @RedPepperNutri: Efficacy of omega-3 PUFAs in depression: A meta-analysis https://t.co/jGy5LIdKxx

Feb 24, 2021 · 2 shares · 6,714 followers View post →

Sian - Red Pepper Nutrition

@RedPepperNutri · X

Efficacy of omega-3 PUFAs in depression: A meta-analysis https://t.co/jGy5LIdKxx

Feb 24, 2021 · 1 like · 2 shares · 830 followers View post →

Chirag Barjatya

@chiragbarjatyaa · X

Nov 18, 2020 · 7 likes · 96,898 followers View post →

Chirag Barjatya

@chiragbarjatyaa · X

https://t.co/cQno6DsaHp

Oct 19, 2020 · 1 like · 96,898 followers View post →

Urvashi Bhagat

@Urvashi_Bhagat · X

Agreed! And at least in part explained by increased conservation (including less loss to lipid per-oxidation) of EPA & DHA, which have benefits against depression https://t.co/BUELisbVo1 https://t.co/Y7E5NN9pKK

Jun 21, 2020 · 1,249 followers View post →

スーツくん

@Suits_loV · X

うつ病にEPAが効くメタ分析より 100%DHAおよび60%以上のDHA製剤はそのような利点を示さなかったが、 1g / 日以下の用量でEPA≥60％のオメガ-3 が、うつ病に対する有益な効果を示した。https://t.co/ES9lNCwalV

May 25, 2020 · 34 followers View post →

Toppform Oslo

@Toppform_gym · X