Remotely controlled chemomagnetic modulation of targeted neural circuits.

Siyuan Rao, Ritchie Chen, Ava A LaRocca, Michael G Christiansen, Alexander W Senko, Cindy H Shi, Po-Han Chiang, Georgios Varnavides, Jian Xue, Yang Zhou, Seongjun Park, Ruihua Ding, Junsang Moon, Guoping Feng, Polina Anikeeva

October 2019 Nat Nanotechnol

Synopsis of Social media discussions

The discussions reveal a range of reactions, with some users expressing skepticism about the concept of 'remotely controlled' actions in the brain, as seen in phrases like 'tin-foil worthy stuff' and references to conspiracy theories. The choice of words, such as 'remotely controlled' and 'local delivery of neuromodulators,' introduces doubts rather than excitement, suggesting that many participants are cautious or critical rather than fully optimistic about the publication's potential.

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Engagement appears limited, with several posts simply restating the article title rather than deeply analyzing the content.

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Impact
 Moderate level of impact

While there is acknowledgment of the research, many posts question its implications rather than viewing it as groundbreaking.

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Abstract Synopsis

  • This study introduces a novel technique called chemomagnetic modulation that allows for the precise control of specific neural pathways in freely moving subjects.
  • It uses magnetic nanoparticles to trigger the release of small molecules, enabling timely manipulation of neural circuits with a 20-second delay.
  • The method effectively enhances sociability in mice by activating dopamine receptors, offering new possibilities for studying molecular neuroscience in living organisms.