Physiol Rev January 2020 PMID 31437090

SIRT6, a Mammalian Deacylase with Multitasking Abilities.

Andrew R Chang, Christina M Ferrer, Raul Mostoslavsky

Mentions

25
Peak: 12 in Aug 2019
across 3 sources since Aug 2019

Extended reach

75,596
potential audience

Total likes

504

Video views

17,942

Mentions per month

Aug 2019 – May 2024

Where it's discussed

  • X / Twitter18 posts
  • YouTube4 videos
  • Blogs3 articles

AI synopsis

What people are saying

The discussions highlight the perceived importance of SIRT6's multitasking abilities, with phrases like 'critical modulators' and 'therapeutic insights,' showing appreciation for its potential in disease treatment. The tone and context, such as mentions of 'mechanistic insights' and 'cellular homeostasis,' emphasize a budding recognition of its significance, while references to related diseases imply potential real-world impact.

AgreementModerate agreement

Most posts recognize the significance of SIRT6's multifunctional roles, indicating moderate to strong agreement with its importance in biology.

InterestHigh interest

The discussions reflect a high level of curiosity about SIRT6, especially in contexts related to disease mechanisms and potential therapies.

EngagementModerate engagement

Posts include references to detailed functions of SIRT6, such as its role in chromatin deacylation and implications for diseases like cancer and COVID-19, showing a moderate level of engagement.

ImpactModerate impact

The conversations suggest that the findings may influence future research directions and therapeutic approaches, though they do not explicitly assert immediate high impact.

Abstract in brief

  • SIRT6 is a key enzyme in mammals that helps regulate important biological functions such as metabolism, DNA repair, and gene expression, which are essential for maintaining healthy cell and organism function.
  • It acts as a chromatin deacylase, connecting the control of chromatin structure with metabolic processes and DNA repair, highlighting its multitasking abilities.
  • Understanding SIRT6's diverse roles could lead to new therapeutic approaches for diseases like cancer, neurodegeneration, and aging, though future research is needed to fully explore these possibilities.]

Top posts

Most liked on X and Bluesky
Physiological Reviews
@physiolrev · X

Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important functions in maintaining cellular homeostasis. https://t.co/94XgM7BUQw #APS #Sirtuin #cancer #SIRT6 #epigenetics #chromatin #physiolrev https://t.co/GOKf6ZF8Sp

Aug 26, 2019 · 6 likes · 5 shares · 5,237 followers View post →
Physiological Reviews
@physiolrev · X

Recommended Reading about #SIRT7's next door neighbor #SIRT6, a Mammalian Deacylase with Multitasking Abilities https://t.co/78sSKfQXFK #Sirtuin https://t.co/4VqrhalwIO https://t.co/jK9ZUf4okx

Sep 21, 2023 · 5 likes · 1 share · 5,237 followers View post →
epigenetics_papers
@epigen_papers · X

Pubmed: SIRT6, a Mammalian deacylase with multitasking abilities. https://t.co/r97DbHWtds

Aug 23, 2019 · 1 like · 2 shares · 6,728 followers View post →
APS Publications
@APSPublications · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 7,352 followers View post →
APS Publications
@APSPublications · X

SIRT6, a Mammalian deacylase with multitasking abilities - brand new ~invited~ review in @physiolrev! https://t.co/FSKdFXx7s2 https://t.co/xzkyTTqcQO

Aug 23, 2019 · 7,352 followers View post →
APS Publications
@APSPublications · X

SIRT6, a Mammalian Deacylase with Multitasking Abilities - new in @physiolrev #cancer #epigenetics https://t.co/ke71RulwWn https://t.co/LbuUI5evbl

Nov 1, 2019 · 7,352 followers View post →

All mentions

Dr L Boominathan PhD
@DrLBoominathan · X

RT @DrLBoominathan: Role of SIRT6 in physiological processes https://t.co/s39RbxqDiq To gain mechanistic & therapeutic insights into COVI…

May 21, 2024 · 2 shares · 881 followers View post →
Giovanni E Mann
@mann_ivel · X

RT @physiolrev: Recommended Reading about #SIRT7's next door neighbor #SIRT6, a Mammalian Deacylase with Multitasking Abilities https://t.…

Sep 22, 2023 · 1 share · 1,171 followers View post →
Physiological Reviews
@physiolrev · X

Recommended Reading about #SIRT7's next door neighbor #SIRT6, a Mammalian Deacylase with Multitasking Abilities https://t.co/78sSKfQXFK #Sirtuin https://t.co/4VqrhalwIO https://t.co/jK9ZUf4okx

Sep 21, 2023 · 5 likes · 1 share · 5,237 followers View post →
Dr L Boominathan PhD
@DrLBoominathan · X

RT @DrLBoominathan: Role of SIRT6 in physiological processes https://t.co/s39RbxqDiq To gain mechanistic & therapeutic insights into COVI…

Apr 16, 2023 · 2 shares · 881 followers View post →
Dr L Boominathan PhD
@DrLBoominathan · X

Role of SIRT6 in physiological processes https://t.co/s39RbxqDiq To gain mechanistic & therapeutic insights into COVID-19: https://t.co/6ySOYUZzaD https://t.co/3q3H8aVLyL https://t.co/ZGNRi4lnsW Twitter: @DrLBoominathan https://t.co/3MoUT5ZgJ8

Feb 28, 2022 · 2 shares · 881 followers View post →
APS Publications
@APSPublications · X

SIRT6, a Mammalian Deacylase with Multitasking Abilities - new in @physiolrev #cancer #epigenetics https://t.co/ke71RulwWn https://t.co/LbuUI5evbl

Nov 1, 2019 · 7,352 followers View post →
Dr. Kim E. Barrett
@DrKimEBarrett · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 6,496 followers View post →
Giovanni E Mann
@mann_ivel · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 1,171 followers View post →
Hélène PhD
@HelenePhd · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 247 followers View post →
IHEC_Epigenomes
@IHEC_Epigenomes · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 3,148 followers View post →
APS Publications
@APSPublications · X

RT @physiolrev: Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important fun…

Aug 26, 2019 · 5 shares · 7,352 followers View post →
Physiological Reviews
@physiolrev · X

Our new Articles in Press manuscript describes multiple roles of SIRT6, a chromatin deacylase with unique and important functions in maintaining cellular homeostasis. https://t.co/94XgM7BUQw #APS #Sirtuin #cancer #SIRT6 #epigenetics #chromatin #physiolrev https://t.co/GOKf6ZF8Sp

Aug 26, 2019 · 6 likes · 5 shares · 5,237 followers View post →
Cancer News
@Cancer_bio · X

RT @Cancer_bio: SIRT6 a Mammalian deacylase with multitasking abilities.: Mammalian Sirtuins have emerged in recent years as critical modul…

Aug 25, 2019 · 1 share · 1,237 followers View post →
Cancer News
@Cancer_bio · X

SIRT6 a Mammalian deacylase with multitasking abilities.: Mammalian Sirtuins have emerged in recent years as critical modulators of multiple biological processes regulating cellular metabolism DNA repair gene expression and mitochondrial biology. As such… https://t.co/GWV2SM9Cro

Aug 23, 2019 · 1 share · 1,237 followers View post →
Zzznorks
@Zzznorks · X

RT @epigen_papers: Pubmed: SIRT6, a Mammalian deacylase with multitasking abilities. https://t.co/r97DbHWtds

Aug 23, 2019 · 2 shares · 603 followers View post →
APS Publications
@APSPublications · X

SIRT6, a Mammalian deacylase with multitasking abilities - brand new ~invited~ review in @physiolrev! https://t.co/FSKdFXx7s2 https://t.co/xzkyTTqcQO

Aug 23, 2019 · 7,352 followers View post →
Renata Noronha
@RenataNoronha13 · X

RT @epigen_papers: Pubmed: SIRT6, a Mammalian deacylase with multitasking abilities. https://t.co/r97DbHWtds

Aug 23, 2019 · 2 shares · 352 followers View post →
epigenetics_papers
@epigen_papers · X

Pubmed: SIRT6, a Mammalian deacylase with multitasking abilities. https://t.co/r97DbHWtds

Aug 23, 2019 · 1 like · 2 shares · 6,728 followers View post →